FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5647, 317 aa 1>>>pF1KB5647 317 - 317 aa - 317 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9891+/-0.000385; mu= 17.2739+/- 0.024 mean_var=59.1581+/-12.111, 0's: 0 Z-trim(111.1): 50 B-trim: 706 in 1/50 Lambda= 0.166750 statistics sampled from 19597 (19647) to 19597 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.23), width: 16 Scan time: 7.230 The best scores are: opt bits E(85289) NP_963837 (OMIM: 606099) galectin-8 isoform b [Hom ( 317) 2075 507.7 1.3e-143 NP_963838 (OMIM: 606099) galectin-8 isoform b [Hom ( 317) 2075 507.7 1.3e-143 XP_016856763 (OMIM: 606099) PREDICTED: galectin-8 ( 287) 1751 429.7 3.4e-120 XP_016856764 (OMIM: 606099) PREDICTED: galectin-8 ( 226) 1198 296.6 3.1e-80 XP_011542490 (OMIM: 606099) PREDICTED: galectin-8 ( 329) 1198 296.7 4.3e-80 NP_963839 (OMIM: 606099) galectin-8 isoform a [Hom ( 359) 1198 296.7 4.6e-80 NP_006490 (OMIM: 606099) galectin-8 isoform a [Hom ( 359) 1198 296.7 4.6e-80 XP_011525275 (OMIM: 602518) PREDICTED: galectin-4 ( 310) 722 182.2 1.2e-45 XP_006721955 (OMIM: 601879) PREDICTED: galectin-9 ( 311) 680 172.1 1.3e-42 NP_149092 (OMIM: 606096) galectin-12 isoform 2 [Ho ( 336) 452 117.3 4.6e-26 NP_001136007 (OMIM: 606096) galectin-12 isoform 1 ( 337) 441 114.6 2.9e-25 XP_016873947 (OMIM: 606096) PREDICTED: galectin-12 ( 252) 424 110.4 3.9e-24 NP_006140 (OMIM: 602518) galectin-4 [Homo sapiens] ( 323) 424 110.5 4.7e-24 NP_001136008 (OMIM: 606096) galectin-12 isoform 3 ( 327) 414 108.1 2.5e-23 XP_011525276 (OMIM: 602518) PREDICTED: galectin-4 ( 192) 403 105.3 1e-22 XP_006721958 (OMIM: 601879) PREDICTED: galectin-9 ( 234) 390 102.2 1.1e-21 NP_001136009 (OMIM: 606096) galectin-12 isoform 4 ( 275) 383 100.6 3.9e-21 NP_001136010 (OMIM: 606096) galectin-12 isoform 5 ( 266) 345 91.5 2.1e-18 XP_011523098 (OMIM: 601879) PREDICTED: galectin-9 ( 221) 342 90.7 3e-18 NP_001317092 (OMIM: 601879) galectin-9 isoform 3 [ ( 246) 342 90.7 3.3e-18 NP_002297 (OMIM: 153619) galectin-3 isoform 1 [Hom ( 250) 342 90.7 3.3e-18 XP_011535061 (OMIM: 153619) PREDICTED: galectin-3 ( 264) 342 90.7 3.5e-18 XP_006721956 (OMIM: 601879) PREDICTED: galectin-9 ( 278) 342 90.7 3.6e-18 NP_002299 (OMIM: 601879) galectin-9 isoform short ( 323) 342 90.8 4.1e-18 XP_016880112 (OMIM: 601879) PREDICTED: galectin-9 ( 343) 342 90.8 4.3e-18 NP_033665 (OMIM: 601879) galectin-9 isoform long [ ( 355) 342 90.8 4.4e-18 NP_001035972 (OMIM: 617139) galectin-7 [Homo sapie ( 136) 277 74.9 1e-13 NP_002298 (OMIM: 600615) galectin-7 [Homo sapiens] ( 136) 277 74.9 1e-13 NP_001819 (OMIM: 153310) galectin-10 [Homo sapiens ( 142) 214 59.8 3.9e-09 NP_002296 (OMIM: 150570) galectin-1 [Homo sapiens] ( 135) 205 57.6 1.7e-08 NP_982297 (OMIM: 607260) placental protein 13-like ( 168) 194 55.0 1.2e-07 NP_006489 (OMIM: 150571,608446) galectin-2 [Homo s ( 132) 192 54.5 1.4e-07 NP_064514 (OMIM: 607260) placental protein 13-like ( 139) 189 53.8 2.5e-07 NP_037400 (OMIM: 608717) galactoside-binding solub ( 139) 171 49.4 4.9e-06 NP_001170859 (OMIM: 153619) galectin-3 isoform 2 [ ( 200) 154 45.4 0.00011 XP_011525176 (OMIM: 608717) PREDICTED: galactoside ( 132) 143 42.7 0.0005 XP_016882204 (OMIM: 608717) PREDICTED: galactoside ( 170) 143 42.8 0.00062 >>NP_963837 (OMIM: 606099) galectin-8 isoform b [Homo sa (317 aa) initn: 2075 init1: 2075 opt: 2075 Z-score: 2699.4 bits: 507.7 E(85289): 1.3e-143 Smith-Waterman score: 2075; 98.7% identity (99.4% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: NP_963 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PQLSLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 PQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI 250 260 270 280 290 300 310 pF1KB5 DTLEINGDIHLLEVRSW ::::::::::::::::: NP_963 DTLEINGDIHLLEVRSW 310 >>NP_963838 (OMIM: 606099) galectin-8 isoform b [Homo sa (317 aa) initn: 2075 init1: 2075 opt: 2075 Z-score: 2699.4 bits: 507.7 E(85289): 1.3e-143 Smith-Waterman score: 2075; 98.7% identity (99.4% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: NP_963 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PQLSLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 PQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI 250 260 270 280 290 300 310 pF1KB5 DTLEINGDIHLLEVRSW ::::::::::::::::: NP_963 DTLEINGDIHLLEVRSW 310 >>XP_016856763 (OMIM: 606099) PREDICTED: galectin-8 isof (287 aa) initn: 1750 init1: 1750 opt: 1751 Z-score: 2278.8 bits: 429.7 E(85289): 3.4e-120 Smith-Waterman score: 1751; 93.7% identity (95.8% similar) in 287 aa overlap (1-287:1-285) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: XP_016 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PQLSLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI :::::::::::::::::::::::::::: : : . :.:..: XP_016 RNSFLQESWGEEERNITSFPFSPGMYFEPHI--DRNLTRKLVSGLESHI 250 260 270 280 310 pF1KB5 DTLEINGDIHLLEVRSW >>XP_016856764 (OMIM: 606099) PREDICTED: galectin-8 isof (226 aa) initn: 1195 init1: 1195 opt: 1198 Z-score: 1561.4 bits: 296.6 E(85289): 3.1e-80 Smith-Waterman score: 1198; 89.8% identity (95.1% similar) in 206 aa overlap (1-206:1-204) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: XP_016 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PQLSLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV ::: .. . . ..: ::: .:.. XP_016 PQLPSNRGGDI-SKIAP-RTVYTKSKDSTVNHTLTCTKIPPMNYVSKV 190 200 210 220 >>XP_011542490 (OMIM: 606099) PREDICTED: galectin-8 isof (329 aa) initn: 1737 init1: 1195 opt: 1198 Z-score: 1559.0 bits: 296.7 E(85289): 4.3e-80 Smith-Waterman score: 1657; 81.8% identity (83.6% similar) in 329 aa overlap (1-287:1-327) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: XP_011 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 pF1KB5 PQLS------------------------------------------LPFAARLNTPMGPG ::: :::::::::::::: XP_011 PQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTKIPPMNYVSKRLPFAARLNTPMGPG 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB5 RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB5 FPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW :::::::::: : : . :.:..: XP_011 FPFSPGMYFEPHI--DRNLTRKLVSGLESHI 310 320 >>NP_963839 (OMIM: 606099) galectin-8 isoform a [Homo sa (359 aa) initn: 2062 init1: 1195 opt: 1198 Z-score: 1558.4 bits: 296.7 E(85289): 4.6e-80 Smith-Waterman score: 1910; 86.8% identity (87.4% similar) in 349 aa overlap (1-307:1-349) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: NP_963 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 pF1KB5 PQLS------------------------------------------LPFAARLNTPMGPG ::: :::::::::::::: NP_963 PQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTKIPPMNYVSKRLPFAARLNTPMGPG 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB5 RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB5 FPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW ::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 FPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW 310 320 330 340 350 >>NP_006490 (OMIM: 606099) galectin-8 isoform a [Homo sa (359 aa) initn: 2062 init1: 1195 opt: 1198 Z-score: 1558.4 bits: 296.7 E(85289): 4.6e-80 Smith-Waterman score: 1910; 86.8% identity (87.4% similar) in 349 aa overlap (1-307:1-349) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA ::::::::::::::::::.:::::::::::::::: :::::::::::::::::::.:::: NP_006 MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT 130 140 150 160 170 180 190 pF1KB5 PQLS------------------------------------------LPFAARLNTPMGPG ::: :::::::::::::: NP_006 PQLPSNRGGDISKIAPRTVYTKSKDSTVNHTLTCTKIPPMNYVSKRLPFAARLNTPMGPG 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB5 RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB5 FPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW ::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW 310 320 330 340 350 >>XP_011525275 (OMIM: 602518) PREDICTED: galectin-4 isof (310 aa) initn: 702 init1: 386 opt: 722 Z-score: 940.5 bits: 182.2 E(85289): 1.2e-45 Smith-Waterman score: 722; 38.9% identity (66.3% similar) in 303 aa overlap (13-315:13-309) 10 20 30 40 50 60 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHVPSDADRFQVDLQNGSSVKPRA :::..:: :: :. : . : : . :: :.. :.. : . XP_011 MAYVPAPGYQPTYNPTLPYYQPIPGGLNVGMSVYIQGVASEHMKRFFVNFVVGQD--PGS 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG :::::::::: .: ::: . ::: :: . :::. .::.:..:: ....:.::: XP_011 DVAFHFNPRFDGWDKVVFNTLQGGKWGSEERKRSMPFKKGAAFELVFIVLAEHYKVVVNG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT . ::::. . . : . : ....::.: .. :. :. . . :. : . XP_011 NPFYEYGHRLPLQMVTHLQVDGDLQLQSINFIGGQPLRP-QGPPMMPPYPTMEGPPTFNP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 PQLSLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV : .:. .::. . ::...:: : ..::: ... .:.: :::::.:::.. . : XP_011 P---VPYFGRLQGGLTARRTIIIKGYVPPTGKSFAINFKVGSSGDIALHINPRMGNGTVV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI :::.:. ::: ::..:: ::.::..:.. : : . .::: .:: : ... ::.. .. . XP_011 RNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHRLSAFQRV 240 250 260 270 280 290 310 pF1KB5 DTLEINGDIHLLEVRSW :::::.::. : :. XP_011 DTLEIQGDVTLSYVQI 300 310 >>XP_006721955 (OMIM: 601879) PREDICTED: galectin-9 isof (311 aa) initn: 538 init1: 271 opt: 680 Z-score: 885.9 bits: 172.1 E(85289): 1.3e-42 Smith-Waterman score: 680; 34.6% identity (68.2% similar) in 318 aa overlap (3-316:1-311) 10 20 30 40 50 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICGHV-PSDADRFQVDLQNGSSVKPR ..... : .:..:. ::: :. : :.. : : :.. :: :..:.: : . XP_006 MAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGN-- 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 ADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVN :.::::::::. .: .:::: : .:: :: ::.. :.. ..: .. :.: :: XP_006 -DIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 GKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSG : . : ::. ...::... :.:.. :.:. .. ....:.. .. .: .: XP_006 GILFVQYFHRVPFHRVDTISVNGSVQLSYISFQTQTVIHTVQSAPGQM--FSTPAIPPMM 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 TPQ--LSLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIK :. .:: . . . :.......: : .:. :...: .:. ::.:::::.. . XP_006 YPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGN--HIAFHLNPRFDEN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AFVRNSFLQESWGEEERNIT-SFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKE : :::. ...::: :::.. ..:: :. : . : :... .::::.: : .:: ::... XP_006 AVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRN 240 250 260 270 280 290 300 310 pF1KB5 LSSIDTLEINGDIHLLEVRSW : .:. ::..:::.: .:.. XP_006 LPTINRLEVGGDIQLTHVQT 300 310 >>NP_149092 (OMIM: 606096) galectin-12 isoform 2 [Homo s (336 aa) initn: 499 init1: 246 opt: 452 Z-score: 588.9 bits: 117.3 E(85289): 4.6e-26 Smith-Waterman score: 529; 32.9% identity (60.1% similar) in 316 aa overlap (8-316:38-336) 10 20 30 pF1KB5 MMLSLNNLQNIIYNPVIPYVGTIPDQLDPGTLIVICG :: ...::.::: :: : : .... : NP_149 RAPGTRIYSWSCPTVMSPGEKLDPIPDSFILQPPVFHPVVPYVTTIFGGLHAGKMVMLQG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 HVPSDADRFQVDLQNGSSVKPRADVAFHFNPRFKRAG-CIVCNTLINEKWGREEITYDTP :: :: :::::.: : :. :: :.::::::::. . ..:::: . .: :: NP_149 VVPLDAHRFQVDFQCGCSLCPRPDIAFHFNPRFHTTKPHVICNTLHGGRWQREARWPHLA 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 FKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSD ..: .:: :... ... .:.:::.: : . .:. ..:::::.: . ....:: NP_149 LRRGSSFLILFLFGNEEVKVSVNGQHFLHFRYRLPLSHVDTLGIFGDILVEAVGF----- 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 LQSTQASSLELTEISRENVPKSG-----TPQLSLPFAARLNTPMGPGRTVVVKGEVNANA :. . ..: ::: : . .:.: .: . : ..::....:.: : . NP_149 LNINP-----FVEGSRE-YPAGHPFLLMSPRLEVPCSHALPQGLSPGQVIIVRGLVLQEP 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 KSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQES-WGEEERNITSFPFSPGMYFEMI : :.:.: .: : : : .:. .. : ::... . : : : .::.. NP_149 KHFTVSL-----RDQAAH-APVTLRASFADRTLAWISRWGQKKLISAPFLFYPQRFFEVL 240 250 260 270 280 290 280 290 300 310 pF1KB5 IYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW . . .:.:.:: . . : .. :.:.:...: :.: NP_149 LLFQEGGLKLALNGQGLGATSMNQQALEQLRELRISGSVQLYCVHS 300 310 320 330 317 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:00:53 2016 done: Fri Nov 4 04:00:54 2016 Total Scan time: 7.230 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]