FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5654, 331 aa 1>>>pF1KB5654 331 - 331 aa - 331 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2679+/-0.000968; mu= 16.0749+/- 0.058 mean_var=64.1818+/-12.643, 0's: 0 Z-trim(104.6): 28 B-trim: 31 in 1/49 Lambda= 0.160092 statistics sampled from 7963 (7982) to 7963 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.245), width: 16 Scan time: 2.330 The best scores are: opt bits E(32554) CCDS968.1 CTSS gene_id:1520|Hs108|chr1 ( 331) 2292 538.2 3.5e-153 CCDS55634.1 CTSS gene_id:1520|Hs108|chr1 ( 281) 1378 327.1 1.1e-89 CCDS969.1 CTSK gene_id:1513|Hs108|chr1 ( 329) 1241 295.5 4.1e-80 CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 ( 334) 1119 267.3 1.3e-71 CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 ( 333) 1101 263.1 2.2e-70 CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 ( 335) 723 175.8 4.3e-44 CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 ( 484) 561 138.5 1.1e-32 CCDS3794.1 CTSO gene_id:1519|Hs108|chr4 ( 321) 502 124.8 9.6e-29 CCDS8117.1 CTSW gene_id:1521|Hs108|chr11 ( 376) 391 99.2 5.7e-21 CCDS13474.1 CTSZ gene_id:1522|Hs108|chr20 ( 303) 272 71.6 8.9e-13 >>CCDS968.1 CTSS gene_id:1520|Hs108|chr1 (331 aa) initn: 2292 init1: 2292 opt: 2292 Z-score: 2863.7 bits: 538.2 E(32554): 3.5e-153 Smith-Waterman score: 2292; 99.7% identity (99.7% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNWILPDSVD :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS96 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW 250 260 270 280 290 300 310 320 330 pF1KB5 GHNFGEEGYIRMARNKGNHCGIASFPSYPEI ::::::::::::::::::::::::::::::: CCDS96 GHNFGEEGYIRMARNKGNHCGIASFPSYPEI 310 320 330 >>CCDS55634.1 CTSS gene_id:1520|Hs108|chr1 (281 aa) initn: 1377 init1: 1377 opt: 1378 Z-score: 1723.9 bits: 327.1 E(32554): 1.1e-89 Smith-Waterman score: 1853; 84.9% identity (84.9% similar) in 331 aa overlap (1-331:1-281) 10 20 30 40 50 60 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNWILPDSVD ::::::::::::::::::::::: CCDS55 LHNLEHSMGMHSYDLGMNHLGDM------------------------------------- 70 80 130 140 150 160 170 180 pF1KB5 WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC ::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 -------------GSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC 90 100 110 120 130 190 200 210 220 230 240 pF1KB5 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB5 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW 200 210 220 230 240 250 310 320 330 pF1KB5 GHNFGEEGYIRMARNKGNHCGIASFPSYPEI ::::::::::::::::::::::::::::::: CCDS55 GHNFGEEGYIRMARNKGNHCGIASFPSYPEI 260 270 280 >>CCDS969.1 CTSK gene_id:1513|Hs108|chr1 (329 aa) initn: 1097 init1: 467 opt: 1241 Z-score: 1551.8 bits: 295.5 E(32554): 4.1e-80 Smith-Waterman score: 1241; 55.8% identity (79.9% similar) in 328 aa overlap (7-331:6-329) 10 20 30 40 50 60 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM :::. . : :. . :: ::.:::::. :::..: .: ::::::::::.. CCDS96 MWGLKVLLLPVVSFA-LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYIS 10 20 30 40 50 70 80 90 100 110 pF1KB5 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNWI--LPDS .:::: :.:.:.:.:.::::::::::::.. :..:.:: . .:. :.: ::: CCDS96 IHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK ::.:.:: :: :: ::.::.:::::.:::::.::: :::::..:: :::::: .: : CCDS96 VDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---ND 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVL ::.::.::.::::. :.::::. .::: .....:.:. .:: : : :.: : : .: CCDS96 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYWLVK :.::: :::::..:: :: .: .::::. :: ..:.::.::.:::: .:...:..: CCDS96 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 240 250 260 270 280 290 300 310 320 330 pF1KB5 NSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI ::::.:.:..::: :::::.: ::::.. :.:.. CCDS96 NSWGENWGNKGYILMARNKNNACGIANLASFPKM 300 310 320 >>CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 (334 aa) initn: 1056 init1: 363 opt: 1119 Z-score: 1399.5 bits: 267.3 E(32554): 1.3e-71 Smith-Waterman score: 1119; 50.6% identity (78.5% similar) in 326 aa overlap (12-331:15-334) 10 20 30 40 50 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLK .::: .. : .:: .:. :: :. . : :::. :: .::::.: CCDS67 MNLSLVLAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMK 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 FVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNWI-LP .. ::: :.:.: :.. ..:: .::::.:: ..:. .: ...... ... .: .. :: CCDS67 MIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFR-NQKFRKGKVFR-EPLFLDLP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 DSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYG :::::.:: :: :: : .::.::::::.::::.:. ::::::::: ::::::: . : CCDS67 KSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-G 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 NKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRED :.:::::::. ::::. .: :.::. :::: :.:. :.: . .:. . .: . :.: CCDS67 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 VLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYG----DLNGK .: .:::. ::.::..:: : :: .:.::.:.::.:. .:..::::::::: . :.. CCDS67 ALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNS 240 250 260 270 280 290 300 310 320 330 pF1KB5 EYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI .::::::::: ..: .::...:..:.::::::. :::.. CCDS67 KYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 300 310 320 330 >>CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 (333 aa) initn: 937 init1: 293 opt: 1101 Z-score: 1377.0 bits: 263.1 E(32554): 2.2e-70 Smith-Waterman score: 1101; 49.7% identity (75.6% similar) in 328 aa overlap (14-331:15-333) 10 20 30 40 50 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFV : : : : .:. .: :: ... : :::. :: .::::.:.. CCDS66 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGM-NEEGWRRAVWEKNMKMI 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 MLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL--RVPSQ---WQRNITYKSNPNWI ::: :. : ::. ..:: .::::::: ..:... : : . .:. . :.. CCDS66 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA----- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK : :::::::: :: :: ::.::.::::::.::::.:. :::.:.::: ::::::: . CCDS66 -PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR ::.:::::.: ::::. :: :.::. ::::.: ...:.:. :: .:. . ....: . CCDS66 -GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-Q 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYG----DLN : .: .:::. ::.::..:: : ::..:. :.:.::.:. ....::::::::: . . CCDS66 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 240 250 260 270 280 290 290 300 310 320 330 pF1KB5 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI ...:::::::::...: ::..::... ::::::: ::: . CCDS66 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 300 310 320 330 >>CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 (335 aa) initn: 401 init1: 193 opt: 723 Z-score: 905.1 bits: 175.8 E(32554): 4.3e-44 Smith-Waterman score: 723; 37.6% identity (66.1% similar) in 327 aa overlap (10-329:19-331) 10 20 30 40 50 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRL- ::..: .: . :.. : . . : : ..:: .:: CCDS10 MWATLPLLCAGAWLLGVPVCGAA--ELCVNSLEKFHFKSWMSKHRKTY--STEEYHHRLQ 10 20 30 40 50 60 70 80 90 100 pF1KB5 IWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMS--LMSSLRVPSQWQRNITYK . .: . . :: : :.. ...:...::. :. : : . : . : CCDS10 TFASNWRKINAHN----NGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 SNPNWILPDSVDWREKGC-VTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNL ..: : :::::.:: :. :: ::.::.::.::..::::. . . :::..::. :.: CCDS10 TGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQL 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 VDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKY :::. . ..:.::.::. . ::.::. :::: .. .:::.. : :... . . CCDS10 VDCA-QDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDV 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 TELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN---VNHGVLVVG ... :... :::: .::: . .. . .:..::.:.: :: .. :::.::.:: CCDS10 ANITIYDEEAMVEAVALYNPVSFAFEVTQ-DFMMYRTGIYSSTSCHKTPDKVNHAVLAVG 230 240 250 260 270 280 290 300 310 320 330 pF1KB5 YGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI ::. :: ::.:::::: ..: .::. . :.: : ::.:. ::: CCDS10 YGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPIPLV 290 300 310 320 330 >>CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 (484 aa) initn: 380 init1: 222 opt: 561 Z-score: 700.5 bits: 138.5 E(32554): 1.1e-32 Smith-Waterman score: 561; 31.3% identity (65.3% similar) in 326 aa overlap (12-327:164-479) 10 20 30 pF1KB5 MKRLVCVLLVCSSAVAQLHKDP-TLD---HHWHLWKK---T ::... :..:: . : . ..:. : CCDS81 AGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLPVKMASIFKNFVIT 140 150 160 170 180 190 40 50 60 70 80 90 pF1KB5 YGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSS :.. :. :.: : .. .:. : .... .. . . :.....:.: :: ... . CCDS81 YNRTYESKEEARWRLSVFVNNM--VRAQKIQ-ALDRGTAQYGVTKFSDLTEEEFRTIYLN 200 210 220 230 240 250 100 110 120 130 140 150 pF1KB5 LRVPSQWQRNITYKSNPNWILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL . .. .. .. . . : ::: :: ::.:: :: ::.:::::..: .:.: : CCDS81 TLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL 260 270 280 290 300 310 160 170 180 190 200 210 pF1KB5 KTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ . : :.::: :.:.:: .:. .:.: ::. ..:.. : . :.... .: :.. :.:. CCDS81 NQGTLLSLSEQELLDC--DKM-DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCN 320 330 340 350 360 220 230 240 250 260 270 pF1KB5 YDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYY--EPSC .... . . .:: . :. : .:..::.::...: .: :: :. .: : CCDS81 FSAEKAKVYINDSVELSQN-EQKLAAWLAKRGPISVAINAFGMQF--YRHGISRPLRPLC 370 380 390 400 410 420 280 290 300 310 320 330 pF1KB5 TQN-VNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI . ..:.::.::::. . .: .::::: ..::.:: . :..: ::. .. : CCDS81 SPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGA-CGVNTMASSAVV 430 440 450 460 470 480 CCDS81 D >>CCDS3794.1 CTSO gene_id:1519|Hs108|chr4 (321 aa) initn: 398 init1: 241 opt: 502 Z-score: 629.6 bits: 124.8 E(32554): 9.6e-29 Smith-Waterman score: 502; 35.8% identity (64.6% similar) in 254 aa overlap (76-323:68-313) 50 60 70 80 90 100 pF1KB5 AVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRV-PSQWQRN :.:... . :: ... :: ::.. : CCDS37 EREAAAFRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIY--LRSKPSKFPRY 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB5 IT--YKSNPNWILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL . . : :: :: :::.: ::.:. : ::.:::::.:::.:. .: : .: CCDS37 SAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDL 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB5 SAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK-GIDSDASYPYKAMDQKCQYDSKYRA :.:...::: :.: ::::: .:.... . . .:. ::.::.. :.: : .. CCDS37 SVQQVIDCS---YNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSGSHS 160 170 180 190 200 210 230 240 250 260 270 pF1KB5 ATCSK-YTELPYG-REDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHG . : :. .. .:: . .:. . ::. : ::: :. : .:. . . ..::. CCDS37 GFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAV--SWQDYLGGIIQHHCSSGEANHA 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB5 VLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI ::..:. .. ::.:.:::: ..: .:: .. . .: :::: CCDS37 VLITGFDKTGSTPYWIVRNSWGSSWGVDGYAHV-KMGSNVCGIADSVSSIFV 280 290 300 310 320 >>CCDS8117.1 CTSW gene_id:1521|Hs108|chr11 (376 aa) initn: 383 init1: 125 opt: 391 Z-score: 490.0 bits: 99.2 E(32554): 5.7e-21 Smith-Waterman score: 488; 30.6% identity (64.3% similar) in 333 aa overlap (24-326:38-358) 10 20 30 40 50 pF1KB5 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWE : . ..:.. ....: .:.: : :. CCDS81 SCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFA 10 20 30 40 50 60 60 70 80 90 100 pF1KB5 KNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLR----VPSQWQRNITYKS .:: .. . :...: . ..:.. ..:.: :: .:.. : :::. :.: . CCDS81 HNLAQAQ-RLQEEDLG--TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSM-GREIR-SE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 NPNWILPDSVDWRE-KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLV .:. .: : :::. . .. .: : .:. :::..:.: .:. ... .:..:.:.:. CCDS81 EPEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPY--KAMDQKCQYDSKYRAATCSK ::. . :. ::.:::. :: ...:.:. :. .::. :. ..:. . ..: . CCDS81 DCG--RCGD-GCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQD 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 YTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYE-PS-CT-QNVNHGVLVV . : . : . . .:. ::..: .. . : . :::.:: :. : : :.:.::.: CCDS81 FIMLQ-NNEHRIAQYLATYGPITVTINMK-P-LQLYRKGVIKATPTTCDPQLVDHSVLLV 240 250 260 270 280 290 290 300 310 320 pF1KB5 GYGDLNGKE--------------------YWLVKNSWGHNFGEEGYIRMARNKGNHCGIA :.:.....: ::..::::: ..::.::.:. :.. : :::. CCDS81 GFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGS-NTCGIT 300 310 320 330 340 350 330 pF1KB5 SFPSYPEI .:: CCDS81 KFPLTARVQKPDMKPRVSCPP 360 370 >>CCDS13474.1 CTSZ gene_id:1522|Hs108|chr20 (303 aa) initn: 309 init1: 148 opt: 272 Z-score: 342.8 bits: 71.6 E(32554): 8.9e-13 Smith-Waterman score: 370; 33.9% identity (59.4% similar) in 224 aa overlap (115-312:62-275) 90 100 110 120 130 pF1KB5 SEEVMSLMSSLRVPSQWQRNITYKSNPNWILPDSVDWREKGCVTEVKYQGS------CGA :: : :::. :. .. . ::. CCDS13 TCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGS 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 CWAFSAVGALEAQLKLKT-GKLVS--LSAQNLVDCSTEKYGNKG-CNGGFMTTAFQYIID ::: ....:. ....: : : ::.::..:: :: : :.:: ....: CCDS13 CWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDC-----GNAGSCEGGNDLSVWDYA-H 100 110 120 130 140 200 210 220 230 pF1KB5 NKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTEL------------PYG----REDVL ..:: ... :.: ::.: :. . .::... : :: :: .. CCDS13 QHGIPDETCNNYQAKDQEC--DKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMM 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 KEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKN : :: ::.: :. : . . : .:.: : . : .:: : :.:.: .: :::.:.: CCDS13 AEIYAN-GPISCGIMATE-RLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRN 210 220 230 240 250 260 300 310 320 330 pF1KB5 SWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI :::. .::.:..:. CCDS13 SWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV 270 280 290 300 331 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:10:23 2016 done: Sat Nov 5 13:10:24 2016 Total Scan time: 2.330 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]