FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5655, 1228 aa 1>>>pF1KB5655 1228 - 1228 aa - 1228 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2925+/-0.00063; mu= 9.8926+/- 0.039 mean_var=258.2140+/-51.714, 0's: 0 Z-trim(112.0): 222 B-trim: 934 in 1/57 Lambda= 0.079815 statistics sampled from 20487 (20711) to 20487 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.243), width: 16 Scan time: 14.720 The best scores are: opt bits E(85289) NP_031377 (OMIM: 601456) multimerin-1 precursor [H (1228) 7936 929.3 0 XP_016863382 (OMIM: 601456) PREDICTED: multimerin- (1228) 7936 929.3 0 XP_005262913 (OMIM: 601456) PREDICTED: multimerin- (1193) 5845 688.5 6.9e-197 NP_079032 (OMIM: 608925) multimerin-2 precursor [H ( 949) 313 51.4 3.4e-05 NP_008977 (OMIM: 130660) EMILIN-1 precursor [Homo (1016) 311 51.2 4.2e-05 >>NP_031377 (OMIM: 601456) multimerin-1 precursor [Homo (1228 aa) initn: 7936 init1: 7936 opt: 7936 Z-score: 4956.9 bits: 929.3 E(85289): 0 Smith-Waterman score: 7936; 100.0% identity (100.0% similar) in 1228 aa overlap (1-1228:1-1228) 10 20 30 40 50 60 pF1KB5 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE 1150 1160 1170 1180 1190 1200 1210 1220 pF1KB5 VWLRLAKGTIPAKFPPVTTFSGYLLYRT :::::::::::::::::::::::::::: NP_031 VWLRLAKGTIPAKFPPVTTFSGYLLYRT 1210 1220 >>XP_016863382 (OMIM: 601456) PREDICTED: multimerin-1 is (1228 aa) initn: 7936 init1: 7936 opt: 7936 Z-score: 4956.9 bits: 929.3 E(85289): 0 Smith-Waterman score: 7936; 100.0% identity (100.0% similar) in 1228 aa overlap (1-1228:1-1228) 10 20 30 40 50 60 pF1KB5 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE 1150 1160 1170 1180 1190 1200 1210 1220 pF1KB5 VWLRLAKGTIPAKFPPVTTFSGYLLYRT :::::::::::::::::::::::::::: XP_016 VWLRLAKGTIPAKFPPVTTFSGYLLYRT 1210 1220 >>XP_005262913 (OMIM: 601456) PREDICTED: multimerin-1 is (1193 aa) initn: 5811 init1: 5811 opt: 5845 Z-score: 3655.8 bits: 688.5 E(85289): 6.9e-197 Smith-Waterman score: 7618; 97.1% identity (97.1% similar) in 1228 aa overlap (1-1228:1-1193) 10 20 30 40 50 60 pF1KB5 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT ::::::::::::::::::::::::::::::::::::::::::: XP_005 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLR----------------- 250 260 270 280 310 320 330 340 350 360 pF1KB5 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE :::::::::::::::::::::::::::::::::::::::::: XP_005 ------------------EVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE 290 300 310 320 370 380 390 400 410 420 pF1KB5 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB5 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB5 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB5 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB5 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB5 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB5 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH 690 700 710 720 730 740 790 800 810 820 830 840 pF1KB5 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN 750 760 770 780 790 800 850 860 870 880 890 900 pF1KB5 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN 810 820 830 840 850 860 910 920 930 940 950 960 pF1KB5 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ 870 880 890 900 910 920 970 980 990 1000 1010 1020 pF1KB5 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN 930 940 950 960 970 980 1030 1040 1050 1060 1070 1080 pF1KB5 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL 990 1000 1010 1020 1030 1040 1090 1100 1110 1120 1130 1140 pF1KB5 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP 1050 1060 1070 1080 1090 1100 1150 1160 1170 1180 1190 1200 pF1KB5 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE 1110 1120 1130 1140 1150 1160 1210 1220 pF1KB5 VWLRLAKGTIPAKFPPVTTFSGYLLYRT :::::::::::::::::::::::::::: XP_005 VWLRLAKGTIPAKFPPVTTFSGYLLYRT 1170 1180 1190 >>NP_079032 (OMIM: 608925) multimerin-2 precursor [Homo (949 aa) initn: 360 init1: 161 opt: 313 Z-score: 214.3 bits: 51.4 E(85289): 3.4e-05 Smith-Waterman score: 444; 21.9% identity (50.5% similar) in 1092 aa overlap (165-1228:9-949) 140 150 160 170 180 190 pF1KB5 SNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPRETYLSRGDSSSSQR .:: : : .: : . . : .: .::. NP_079 MILSLLFSLGGPLGWGLLGAWA-QASSTSLSDLQSSRT 10 20 30 200 210 220 230 240 pF1KB5 TDYQKSNFETTR----GKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGWTGGSCPQRS- :.. : : :.::: : ..: . : . .. .. :: . .: . . NP_079 PGVWKAEAEDTGKDPVGRNWCPYPMSKLVTLLALCKTEKFLIHSQQPCPQGAPDCQKVKV 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB5 --QKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHTAVGRGVA . .:::....:..::: :::::::.::.: ....:. . :. : . NP_079 MYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNC----EHHDSMAIPEPADP------GDS 100 110 120 130 140 310 320 330 340 350 360 pF1KB5 EQQQQQG--CGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVND-VRNTYSSLEGKVS .:. :.: : . . ..:. : . : ..: : : . . ...: :... NP_079 HQEPQDGPVSFKPGHLAAVINEVEVQQEQQEHLLGDLQNDVHRVADSLPGLWKALPGNLT 150 160 170 180 190 200 370 380 390 400 410 420 pF1KB5 EDKSREFQSLLKGLKSKSIN-VLIRDI---VREQFKIFQNDMQETVAQLFKTVSSLSEDL . :. . . ..:.. ::. . .. .:. . ...... .: ... .:: :. NP_079 AAVMEANQTGHE-FPDRSLEQVLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDV 210 220 230 240 250 260 430 440 450 460 470 pF1KB5 ESTRQIIQKVNESVVSIAAQQ----KF-VLVQENRPTLTDIVELRNHIVNVRQEMTLTCE :..:: :..:..:.:. : : :: . :::: . .::. . . . . .: . NP_079 EANRQAISRVQDSAVARADFQELGAKFEAKVQENTQR---VGQLRQDVEDRLHAQHFTLH 270 280 290 300 310 320 480 490 500 510 520 530 pF1KB5 KPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAA . :.:: :. .. :.. :. . . : .: .:.: .. . . . NP_079 RSISEL---QADVDTKLKRLHKAQ--EAPGTNGSL---------VLATPGAGARPEPDSL 330 340 350 360 540 550 560 570 580 590 pF1KB5 ESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESK-INNLTVSLEMEKESLRGECED .. ... . .: :: . .. . .::.. .. .... :. .:: : : NP_079 QARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIK---ELYSES--DETFD 370 380 390 400 410 420 600 610 620 630 640 650 pF1KB5 MLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQP-LL ..:: . . . .:. .. :. : : : . :... ... .:: .:. .. :: NP_079 QISKVERQVE-ELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHA 430 440 450 460 470 480 660 670 680 690 700 710 pF1KB5 EQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDAL . ... . . :::. .. : :.. . . : . . . .:. ::. NP_079 DLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAV 490 500 510 520 530 540 720 730 740 750 760 770 pF1KB5 ERRINEYALEMEDGLNKTMTIINNAIDFIQDNY-ALKETLSTIKDNSEIHHKCTSDMETI .. . : : . : . . . .. ..:. ::: . .: .:. NP_079 SLAVDAHKAEGERARAAT-SRLRSQVQALDDEVGALKAA------AAEARHE-------- 550 560 570 580 780 790 800 810 820 830 pF1KB5 LTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTS . :.: ... .:..: :.. :: :.. .: :.. . : . . NP_079 ---VRQLH---SAFAALLEDALRHEAVL------AALFGEEVLEEMSEQTPGPL-PLSYE 590 600 610 620 630 840 850 860 870 880 890 pF1KB5 QVR-KYQQNMSHLEEKLLLTTKISKNFETRLQDIES-KVTQTLIPYYISVKKGSVVTNER :.: :. : :.:. : ... . : : . .. : : . . .. ...: NP_079 QIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPSHDAGREEAATTALA 640 650 660 670 680 690 900 910 920 930 940 pF1KB5 DQALQLQVLNSRFKAL-EAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWI : .:: :.. : . . . . . ::: .:: . ::: : :: NP_079 GLARELQSLSNDVKNVGRCCEAEAGAGAASLNASLHGL----HNA------LFAT----- 700 710 720 730 740 950 960 970 980 990 1000 pF1KB5 KHSLPDIQLLQKGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSL-- ..:: . : : ..: . ... ... :..: ..: :..:: :.: NP_079 QRSLEQHQRLFHSLFGNFQGLMEANVSLDLGKLQTMLSR----------KGKKQQKDLEA 750 760 770 780 790 1010 1020 1030 1040 1050 1060 pF1KB5 PKKINALKKPTVNLTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCAC :.: : ..... .. . ..: NP_079 PRK-----------------RDKKEAEPLVDIR----------------VTG-------- 800 1070 1080 1090 1100 1110 1120 pF1KB5 RHPFTGDNCTIKLVEENAL-APDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNY : : :: : . :: : :::.:: . : . . ::. .: NP_079 --PVPG-----------ALGAALWEAGS----P-VAFYASFSEGTAALQTVKFNTTYINI 810 820 830 840 850 1130 1140 1150 1160 1170 1180 pF1KB5 GASYTPRTGKFRIPYLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRV :.:: :. : :: : :::.: ..: . .: :: : . . . .: . NP_079 GSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTGQLVFGGHHRTPVCTTGQGS----GST 860 870 880 890 900 1190 1200 1210 1220 pF1KB5 LTGDALLELNYGQEVWLRLAKGTIPAKFPPVTTFSGYLLYRT : :. ::. :..::..:..:.: . :.:.:.:...: NP_079 ATVFAMAELQKGERVWFELTQGSITKRSLSGTAFGGFLMFKT 910 920 930 940 >>NP_008977 (OMIM: 130660) EMILIN-1 precursor [Homo sapi (1016 aa) initn: 277 init1: 189 opt: 311 Z-score: 212.7 bits: 51.2 E(85289): 4.2e-05 Smith-Waterman score: 311; 25.5% identity (58.3% similar) in 235 aa overlap (173-403:20-245) 150 160 170 180 190 200 pF1KB5 QSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPRETYLSRGDSS--SSQRTDYQKS :... :: : :.:. : . : . NP_008 MAPRTLWSCYLCCLLTAAAGAASYPPRGFSLYTGSSGALSPGGPQAQIA 10 20 30 40 210 220 230 240 250 pF1KB5 NFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGWTGGSCPQR--SQKISNPVYR ..: .:::::: :: :. :. ::: ::.: .::: ... : :: NP_008 PRPASRHRNWCAYVVTRTVSCVLEDGVETYVK--YQPCAWGQPQCPQSIMYRRFLRPRYR 50 60 70 80 90 100 260 270 280 290 300 310 pF1KB5 MQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDP . .: ::...:::: ::.: : :. . . . ..: . . . .. :.: NP_008 VAYKTVTDMEWRCCQGYGGDDCA----ESPAPALGPASSTPRPLARPARPNLSGSSAGSP 110 120 130 140 150 160 320 330 340 350 360 370 pF1KB5 EVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGL .. . . .. :. :........ .. .:.. ..: :...:: .: .. ..: NP_008 --LSGLGGEGPGESEKVQQLEEQVQSLTKELQGLRGVLQGLSGRLAEDVQRAVETAFNG- 170 180 190 200 210 220 380 390 400 410 420 430 pF1KB5 KSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIA ... .. : :.: .. .:...: NP_008 RQQPADAAARPGVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGGSRAPAPA 230 240 250 260 270 280 1228 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:52:31 2016 done: Thu Nov 3 17:52:33 2016 Total Scan time: 14.720 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]