FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5659, 308 aa 1>>>pF1KB5659 308 - 308 aa - 308 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1800+/-0.000836; mu= 17.3670+/- 0.051 mean_var=89.7140+/-17.057, 0's: 0 Z-trim(109.4): 58 B-trim: 22 in 1/50 Lambda= 0.135408 statistics sampled from 10801 (10859) to 10801 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.334), width: 16 Scan time: 2.610 The best scores are: opt bits E(32554) CCDS2998.1 FSTL1 gene_id:11167|Hs108|chr3 ( 308) 2146 429.0 2.3e-120 CCDS47157.1 FSTL5 gene_id:56884|Hs108|chr4 ( 837) 304 69.6 9.5e-12 CCDS47158.1 FSTL5 gene_id:56884|Hs108|chr4 ( 846) 304 69.6 9.6e-12 CCDS3802.1 FSTL5 gene_id:56884|Hs108|chr4 ( 847) 304 69.6 9.6e-12 CCDS34238.1 FSTL4 gene_id:23105|Hs108|chr5 ( 842) 299 68.6 1.9e-11 >>CCDS2998.1 FSTL1 gene_id:11167|Hs108|chr3 (308 aa) initn: 2146 init1: 2146 opt: 2146 Z-score: 2274.6 bits: 429.0 E(32554): 2.3e-120 Smith-Waterman score: 2146; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS29 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT 250 260 270 280 290 300 pF1KB5 KRVSTKEI :::::::: CCDS29 KRVSTKEI >>CCDS47157.1 FSTL5 gene_id:56884|Hs108|chr4 (837 aa) initn: 280 init1: 216 opt: 304 Z-score: 324.4 bits: 69.6 E(32554): 9.5e-12 Smith-Waterman score: 322; 30.5% identity (60.0% similar) in 220 aa overlap (31-244:64-265) 10 20 30 40 50 pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVT-EKGEPTCLCIEQCK : : .:: ::.:... : :. : :.. :: CCDS47 QPLMRLRHKEKNQESSRVKGFMIQDGPFGSCENKYCGLGRHCVTSRETGQAECACMDLCK 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB5 PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC--KEKKSVSPSASPVVCYQSN : .:::::.:. : ::::.:: ::: .:: . .. : : : . : . . . CCDS47 RHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKCKTTEYSKMKNMLLD 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB5 RDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFD-NGDSRLDSSEFLKFVEQNE .. .. :.: : : :.: . : . ..:..:: :: .... .: .:. . ..:.: CCDS47 LQN-QKYIMQ--ENEN-PNG--DDISRKKLLVDQMFKYFDADSNGLVDINELTQVIKQEE 160 170 180 190 200 180 190 200 210 220 230 pF1KB5 TAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNP-SFNPPE-KKCA . : : . .:.. .: ::: .:...:: . .. ... :: .: . CCDS47 LG------------KDLFDCTLYVLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQKLS 210 220 230 240 250 240 250 260 270 280 290 pF1KB5 LEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQ . : ...: CCDS47 ITAATVGQSAVLSCAIQGTLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHV 260 270 280 290 300 310 >>CCDS47158.1 FSTL5 gene_id:56884|Hs108|chr4 (846 aa) initn: 280 init1: 216 opt: 304 Z-score: 324.3 bits: 69.6 E(32554): 9.6e-12 Smith-Waterman score: 322; 30.5% identity (60.0% similar) in 220 aa overlap (31-244:64-265) 10 20 30 40 50 pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVT-EKGEPTCLCIEQCK : : .:: ::.:... : :. : :.. :: CCDS47 QPLMRLRHKEKNQESSRVKGFMIQDGPFGSCENKYCGLGRHCVTSRETGQAECACMDLCK 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB5 PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC--KEKKSVSPSASPVVCYQSN : .:::::.:. : ::::.:: ::: .:: . .. : : : . : . . . CCDS47 RHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKCKTTEYSKMKNMLLD 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB5 RDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFD-NGDSRLDSSEFLKFVEQNE .. .. :.: : : :.: . : . ..:..:: :: .... .: .:. . ..:.: CCDS47 LQN-QKYIMQ--ENEN-PNG--DDISRKKLLVDQMFKYFDADSNGLVDINELTQVIKQEE 160 170 180 190 200 180 190 200 210 220 230 pF1KB5 TAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNP-SFNPPE-KKCA . : : . .:.. .: ::: .:...:: . .. ... :: .: . CCDS47 LG------------KDLFDCTLYVLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQKLS 210 220 230 240 250 240 250 260 270 280 290 pF1KB5 LEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQ . : ...: CCDS47 ITAATVGQSAVLSCAIQGTLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHV 260 270 280 290 300 310 >>CCDS3802.1 FSTL5 gene_id:56884|Hs108|chr4 (847 aa) initn: 280 init1: 216 opt: 304 Z-score: 324.3 bits: 69.6 E(32554): 9.6e-12 Smith-Waterman score: 322; 30.5% identity (60.0% similar) in 220 aa overlap (31-244:65-266) 10 20 30 40 50 pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVT-EKGEPTCLCIEQCK : : .:: ::.:... : :. : :.. :: CCDS38 PLMRLRHKQEKNQESSRVKGFMIQDGPFGSCENKYCGLGRHCVTSRETGQAECACMDLCK 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB5 PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC--KEKKSVSPSASPVVCYQSN : .:::::.:. : ::::.:: ::: .:: . .. : : : . : . . . CCDS38 RHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKCKTTEYSKMKNMLLD 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB5 RDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFD-NGDSRLDSSEFLKFVEQNE .. .. :.: : : :.: . : . ..:..:: :: .... .: .:. . ..:.: CCDS38 LQN-QKYIMQ--ENEN-PNG--DDISRKKLLVDQMFKYFDADSNGLVDINELTQVIKQEE 160 170 180 190 200 180 190 200 210 220 230 pF1KB5 TAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNP-SFNPPE-KKCA . : : . .:.. .: ::: .:...:: . .. ... :: .: . CCDS38 LG------------KDLFDCTLYVLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQKLS 210 220 230 240 250 240 250 260 270 280 290 pF1KB5 LEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQ . : ...: CCDS38 ITAATVGQSAVLSCAIQGTLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHV 260 270 280 290 300 310 >>CCDS34238.1 FSTL4 gene_id:23105|Hs108|chr5 (842 aa) initn: 232 init1: 232 opt: 299 Z-score: 319.1 bits: 68.6 E(32554): 1.9e-11 Smith-Waterman score: 328; 28.8% identity (61.5% similar) in 226 aa overlap (18-231:49-254) 10 20 30 40 pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKI---CANVFCGAGRECAV : .: : :.... :.. ::. : .:.. CCDS34 AALGWMDPGTSRGPDVGVGESQAEEPRSFEVTRREGLSSHNELLASCGKKFCSRGSRCVL 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB5 TEK-GEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKS ..: ::: : :.: :.: :::::.:. : :::.::: ::: :..: : .. : : . CCDS34 SRKTGEPECQCLEACRPSYVPVCGSDGRFYENHCKLHRAACLLGKRITVIHSKDCFLKGD 80 90 100 110 120 130 110 120 130 140 150 pF1KB5 VSPSASPVVCYQSNRDELRRRIIQWLEAEIIP----DGWFSKGSNYSEILDKYFKNFD-N . : ... .:. .. :.... : :. . .:. .... :...: . CCDS34 T--------CTMAGYARLKN-VLLALQTRLQPLQEGDSRQDPASQKRLLVESLFRDLDAD 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 GDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEF :...:.:::. . : .. :. .. : : :....: :.: .:...:: CCDS34 GNGHLSSSELAQHVLKK-----------QDLDEDLLGCSPGDLLRFDDYNSDSSLTLREF 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 ---LKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGA .. .. :. : .. CCDS34 YMAFQVVQLSLAPEDRVSVTTVTVGLSTVLTCAVHGDLRPPIIWKRNGLTLNFLDLEDIN 240 250 260 270 280 290 308 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:11:01 2016 done: Sat Nov 5 13:11:01 2016 Total Scan time: 2.610 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]