Result of FASTA (omim) for pF1KB5662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5662, 372 aa
  1>>>pF1KB5662 372 - 372 aa - 372 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.3808+/-0.000364; mu= 1.4572+/- 0.023
 mean_var=369.3764+/-78.452, 0's: 0 Z-trim(124.0): 916  B-trim: 2412 in 1/61
 Lambda= 0.066733
 statistics sampled from 43536 (44740) to 43536 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.525), width:  16
 Scan time:  9.250

The best scores are:                                      opt bits E(85289)
NP_079471 (OMIM: 609461) tribbles homolog 1 isofor ( 372) 2529 256.8 5.7e-68
NP_001269914 (OMIM: 609461) tribbles homolog 1 iso ( 206) 1378 145.7   9e-35
NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo  ( 343) 1266 135.2 2.2e-31
XP_016883478 (OMIM: 607898) PREDICTED: tribbles ho ( 385)  992 108.9   2e-23
NP_001288130 (OMIM: 607898) tribbles homolog 3 iso ( 385)  992 108.9   2e-23
NP_001288122 (OMIM: 607898) tribbles homolog 3 iso ( 358)  988 108.5 2.6e-23
NP_001288125 (OMIM: 607898) tribbles homolog 3 iso ( 358)  988 108.5 2.6e-23
NP_001288119 (OMIM: 607898) tribbles homolog 3 iso ( 358)  988 108.5 2.6e-23
NP_001288117 (OMIM: 607898) tribbles homolog 3 iso ( 358)  988 108.5 2.6e-23
NP_066981 (OMIM: 607898) tribbles homolog 3 isofor ( 358)  988 108.5 2.6e-23
NP_001269476 (OMIM: 609437) serine/threonine-prote ( 435)  421 54.0 7.8e-07
NP_114406 (OMIM: 609437) serine/threonine-protein  ( 435)  421 54.0 7.8e-07
NP_001269475 (OMIM: 609437) serine/threonine-prote ( 440)  421 54.0 7.9e-07
NP_115806 (OMIM: 609235) serine/threonine-protein  ( 778)  422 54.4 1.1e-06
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373)  407 52.5 1.8e-06
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765)  413 53.5 1.9e-06
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765)  413 53.5 1.9e-06
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765)  413 53.5 1.9e-06
NP_006243 (OMIM: 600497) 5'-AMP-activated protein  ( 552)  409 52.9   2e-06
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610)  407 52.8 2.5e-06
NP_001243618 (OMIM: 607025) maternal embryonic leu ( 619)  407 52.8 2.5e-06
XP_011516385 (OMIM: 607025) PREDICTED: maternal em ( 619)  407 52.8 2.5e-06
XP_011516386 (OMIM: 607025) PREDICTED: maternal em ( 619)  407 52.8 2.5e-06
XP_011516384 (OMIM: 607025) PREDICTED: maternal em ( 619)  407 52.8 2.5e-06
XP_011516383 (OMIM: 607025) PREDICTED: maternal em ( 619)  407 52.8 2.5e-06
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622)  407 52.8 2.5e-06
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651)  407 52.8 2.6e-06
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651)  407 52.8 2.6e-06
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651)  407 52.8 2.6e-06
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651)  407 52.8 2.6e-06
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651)  407 52.8 2.6e-06
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660)  402 52.4 3.6e-06
XP_005259384 (OMIM: 609235) PREDICTED: serine/thre ( 688)  402 52.4 3.7e-06
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643)  400 52.2 4.1e-06
NP_742081 (OMIM: 607707) calcium/calmodulin-depend ( 449)  396 51.6 4.2e-06
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708)  400 52.2 4.3e-06
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713)  400 52.2 4.3e-06
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722)  400 52.2 4.4e-06
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728)  400 52.2 4.4e-06
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729)  400 52.2 4.4e-06
NP_742080 (OMIM: 607707) calcium/calmodulin-depend ( 479)  396 51.6 4.4e-06
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737)  400 52.2 4.4e-06
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738)  400 52.2 4.4e-06
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739)  400 52.2 4.4e-06
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744)  400 52.2 4.4e-06
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753)  400 52.2 4.5e-06
NP_742079 (OMIM: 607707) calcium/calmodulin-depend ( 492)  396 51.6 4.5e-06
XP_016868154 (OMIM: 607707) PREDICTED: calcium/cal ( 493)  396 51.6 4.5e-06
XP_005249921 (OMIM: 607707) PREDICTED: calcium/cal ( 494)  396 51.6 4.5e-06
XP_016868153 (OMIM: 607707) PREDICTED: calcium/cal ( 502)  396 51.6 4.5e-06


>>NP_079471 (OMIM: 609461) tribbles homolog 1 isoform 1   (372 aa)
 initn: 2529 init1: 2529 opt: 2529  Z-score: 1341.3  bits: 256.8 E(85289): 5.7e-68
Smith-Waterman score: 2529; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)

               10        20        30        40        50        60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 FCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE
              310       320       330       340       350       360

              370  
pF1KB5 YQEDSDISSFFC
       ::::::::::::
NP_079 YQEDSDISSFFC
              370  

>>NP_001269914 (OMIM: 609461) tribbles homolog 1 isoform  (206 aa)
 initn: 1378 init1: 1378 opt: 1378  Z-score: 745.3  bits: 145.7 E(85289): 9e-35
Smith-Waterman score: 1378; 100.0% identity (100.0% similar) in 206 aa overlap (167-372:1-206)

        140       150       160       170       180       190      
pF1KB5 LPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHC
                                     ::::::::::::::::::::::::::::::
NP_001                               MHSYVRSRKRLREEEAARLFKQIVSAVAHC
                                             10        20        30

        200       210       220       230       240       250      
pF1KB5 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
               40        50        60        70        80        90

        260       270       280       290       300       310      
pF1KB5 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
              100       110       120       130       140       150

        320       330       340       350       360       370  
pF1KB5 SLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
              160       170       180       190       200      

>>NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo sapi  (343 aa)
 initn: 1283 init1: 1215 opt: 1266  Z-score: 684.5  bits: 135.2 E(85289): 2.2e-31
Smith-Waterman score: 1275; 61.9% identity (81.2% similar) in 320 aa overlap (56-371:35-342)

          30        40        50        60         70        80    
pF1KB5 TRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPP-GSPCSPQPPPAAPGAGGGSGS
                                     : . .::  :::  :. :  .  .      
NP_067 RSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCV------
           10        20        30        40        50              

           90       100       110       120       130       140    
pF1KB5 APGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNIT
           : :. ::::   : .:: ::. .:.:.:: :::: :. ::... : . : .::::.
NP_067 ----SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNIN
           60        70        80        90       100       110    

          150       160       170       180       190       200    
pF1KB5 GIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLG
        :.:.::::::::::::...:::::.::. :.:::::::::: ::.:::::::....:: 
NP_067 QITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLR
          120       130       140       150       160       170    

          210       220       230       240       250       260    
pF1KB5 DLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKA
       :::::::.:. ::::...::::::..:..:.::.::::::::::::::::::.:.:::::
NP_067 DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKA
          180       190       200       210       220       230    

          270       280       290       300       310       320    
pF1KB5 ADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPS
       ::::::::::::.::::::::: .::.:::::::::: ::: .::::.:::::.::::::
NP_067 ADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPS
          240       250       260       270       280       290    

          330          340       350       360       370  
pF1KB5 ERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
       ::::. ::: ::::    :: . .:  .:.  :::.::. . . ... :: 
NP_067 ERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
          300       310       320         330       340   

>>XP_016883478 (OMIM: 607898) PREDICTED: tribbles homolo  (385 aa)
 initn: 1019 init1: 928 opt: 992  Z-score: 541.4  bits: 108.9 E(85289): 2e-23
Smith-Waterman score: 992; 46.6% identity (70.1% similar) in 348 aa overlap (15-360:27-365)

                           10        20        30        40        
pF1KB5             MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCP
                                 : :.  :  ::  ..  :. :. ::   . .. :
XP_016 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAG-SLSRKKRLELDDN--LDTERP
               10        20        30         40        50         

       50        60         70        80        90       100       
pF1KB5 RLSECSSPPDYLSPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSR
         ..  : :.   :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .
XP_016 VQKRARSGPQ---PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQ
        60           70        80        90          100       110 

       110       120       130       140       150       160       
pF1KB5 ALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDM
       ::   :: :  :::.:...    ..:: .:: :....  .::. :    :.:: .  :::
XP_016 ALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDM
             120       130       140       150       160       170 

       170       180       190       200       210       220       
pF1KB5 HSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLE
       :: ::::.:. : ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.::
XP_016 HSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLE
             180       190       200       210       220       230 

       230       240       250       260       270       280       
pF1KB5 DTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDS
       :. .. : ::.: :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::
XP_016 DSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDS
             240       250       260       270       280       290 

       290       300       310       320       330       340       
pF1KB5 DPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GY
       .:  ::.::::: . .:  .:  ::::.: ::::::.:::::  ::::::...   : . 
XP_016 EPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAP
             300       310       320       330       340       350 

        350       360       370          
pF1KB5 IDSEIGTSDQIVPEYQEDSDISSFFC        
         :..  . :.::.                    
XP_016 TRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
             360       370       380     

>>NP_001288130 (OMIM: 607898) tribbles homolog 3 isoform  (385 aa)
 initn: 1019 init1: 928 opt: 992  Z-score: 541.4  bits: 108.9 E(85289): 2e-23
Smith-Waterman score: 992; 46.6% identity (70.1% similar) in 348 aa overlap (15-360:27-365)

                           10        20        30        40        
pF1KB5             MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCP
                                 : :.  :  ::  ..  :. :. ::   . .. :
NP_001 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAG-SLSRKKRLELDDN--LDTERP
               10        20        30         40        50         

       50        60         70        80        90       100       
pF1KB5 RLSECSSPPDYLSPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSR
         ..  : :.   :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .
NP_001 VQKRARSGPQ---PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQ
        60           70        80        90          100       110 

       110       120       130       140       150       160       
pF1KB5 ALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDM
       ::   :: :  :::.:...    ..:: .:: :....  .::. :    :.:: .  :::
NP_001 ALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDM
             120       130       140       150       160       170 

       170       180       190       200       210       220       
pF1KB5 HSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLE
       :: ::::.:. : ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.::
NP_001 HSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLE
             180       190       200       210       220       230 

       230       240       250       260       270       280       
pF1KB5 DTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDS
       :. .. : ::.: :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::
NP_001 DSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDS
             240       250       260       270       280       290 

       290       300       310       320       330       340       
pF1KB5 DPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GY
       .:  ::.::::: . .:  .:  ::::.: ::::::.:::::  ::::::...   : . 
NP_001 EPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAP
             300       310       320       330       340       350 

        350       360       370          
pF1KB5 IDSEIGTSDQIVPEYQEDSDISSFFC        
         :..  . :.::.                    
NP_001 TRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
             360       370       380     

>>NP_001288122 (OMIM: 607898) tribbles homolog 3 isoform  (358 aa)
 initn: 1019 init1: 928 opt: 988  Z-score: 539.6  bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)

               10        20        30        40        50        60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
                       :.  :  ::  ..  :. :. ::   . .. :  ..  : :.  
NP_001                MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
                              10         20          30        40  

                70        80        90       100       110         
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
        :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .::   :: :  :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
                50        60           70        80        90      

     120       130       140       150       160       170         
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
       ::.:...    ..:: .:: :....  .::. :    :.:: .  ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
        100       110       120       130       140       150      

     180       190       200       210       220       230         
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
        ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
        160       170       180       190       200       210      

     240       250       260       270       280       290         
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
        :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.:  ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
        220       230       240       250       260       270      

     300       310       320       330       340        350        
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
        . .:  .:  ::::.: ::::::.:::::  ::::::...   : .   :..  . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
        280       290       300       310       320       330      

      360       370          
pF1KB5 PEYQEDSDISSFFC        
       :.                    
NP_001 PDGLGLDEAREEEGDREVVLYG
        340       350        

>>NP_001288125 (OMIM: 607898) tribbles homolog 3 isoform  (358 aa)
 initn: 1019 init1: 928 opt: 988  Z-score: 539.6  bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)

               10        20        30        40        50        60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
                       :.  :  ::  ..  :. :. ::   . .. :  ..  : :.  
NP_001                MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
                              10         20          30        40  

                70        80        90       100       110         
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
        :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .::   :: :  :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
                50        60           70        80        90      

     120       130       140       150       160       170         
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
       ::.:...    ..:: .:: :....  .::. :    :.:: .  ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
        100       110       120       130       140       150      

     180       190       200       210       220       230         
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
        ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
        160       170       180       190       200       210      

     240       250       260       270       280       290         
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
        :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.:  ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
        220       230       240       250       260       270      

     300       310       320       330       340        350        
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
        . .:  .:  ::::.: ::::::.:::::  ::::::...   : .   :..  . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
        280       290       300       310       320       330      

      360       370          
pF1KB5 PEYQEDSDISSFFC        
       :.                    
NP_001 PDGLGLDEAREEEGDREVVLYG
        340       350        

>>NP_001288119 (OMIM: 607898) tribbles homolog 3 isoform  (358 aa)
 initn: 1019 init1: 928 opt: 988  Z-score: 539.6  bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)

               10        20        30        40        50        60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
                       :.  :  ::  ..  :. :. ::   . .. :  ..  : :.  
NP_001                MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
                              10         20          30        40  

                70        80        90       100       110         
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
        :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .::   :: :  :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
                50        60           70        80        90      

     120       130       140       150       160       170         
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
       ::.:...    ..:: .:: :....  .::. :    :.:: .  ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
        100       110       120       130       140       150      

     180       190       200       210       220       230         
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
        ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
        160       170       180       190       200       210      

     240       250       260       270       280       290         
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
        :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.:  ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
        220       230       240       250       260       270      

     300       310       320       330       340        350        
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
        . .:  .:  ::::.: ::::::.:::::  ::::::...   : .   :..  . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
        280       290       300       310       320       330      

      360       370          
pF1KB5 PEYQEDSDISSFFC        
       :.                    
NP_001 PDGLGLDEAREEEGDREVVLYG
        340       350        

>>NP_001288117 (OMIM: 607898) tribbles homolog 3 isoform  (358 aa)
 initn: 1019 init1: 928 opt: 988  Z-score: 539.6  bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)

               10        20        30        40        50        60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
                       :.  :  ::  ..  :. :. ::   . .. :  ..  : :.  
NP_001                MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
                              10         20          30        40  

                70        80        90       100       110         
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
        :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .::   :: :  :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
                50        60           70        80        90      

     120       130       140       150       160       170         
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
       ::.:...    ..:: .:: :....  .::. :    :.:: .  ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
        100       110       120       130       140       150      

     180       190       200       210       220       230         
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
        ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
        160       170       180       190       200       210      

     240       250       260       270       280       290         
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
        :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.:  ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
        220       230       240       250       260       270      

     300       310       320       330       340        350        
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
        . .:  .:  ::::.: ::::::.:::::  ::::::...   : .   :..  . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
        280       290       300       310       320       330      

      360       370          
pF1KB5 PEYQEDSDISSFFC        
       :.                    
NP_001 PDGLGLDEAREEEGDREVVLYG
        340       350        

>>NP_066981 (OMIM: 607898) tribbles homolog 3 isoform 1   (358 aa)
 initn: 1019 init1: 928 opt: 988  Z-score: 539.6  bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)

               10        20        30        40        50        60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
                       :.  :  ::  ..  :. :. ::   . .. :  ..  : :.  
NP_066                MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
                              10         20          30        40  

                70        80        90       100       110         
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
        :   ::  :  ::.::  . . ..:   ::.. :.::   :  .. .::   :: :  :
NP_066 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
                50        60           70        80        90      

     120       130       140       150       160       170         
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
       ::.:...    ..:: .:: :....  .::. :    :.:: .  ::::: ::::.:. :
NP_066 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
        100       110       120       130       140       150      

     180       190       200       210       220       230         
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
        ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_066 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
        160       170       180       190       200       210      

     240       250       260       270       280       290         
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
        :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.:  ::.:::::
NP_066 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
        220       230       240       250       260       270      

     300       310       320       330       340        350        
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
        . .:  .:  ::::.: ::::::.:::::  ::::::...   : .   :..  . :.:
NP_066 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
        280       290       300       310       320       330      

      360       370          
pF1KB5 PEYQEDSDISSFFC        
       :.                    
NP_066 PDGLGLDEAREEEGDREVVLYG
        340       350        




372 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 17:53:43 2016 done: Thu Nov  3 17:53:45 2016
 Total Scan time:  9.250 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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