Result of FASTA (omim) for
pF1KB5674
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5674, 435 aa
1>>>pF1KB5674 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3249+/-0.00032; mu= 9.8932+/- 0.020
mean_var=141.5268+/-27.926, 0's: 0 Z-trim(120.7): 412 B-trim: 0 in 0/57
Lambda= 0.107809
statistics sampled from 35915 (36340) to 35915 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.426), width: 16
Scan time: 9.760
The best scores are: opt bits E(85289)
NP_002818 (OMIM: 125853,176885) tyrosine-protein p ( 435) 2995 477.0 4.2e-134
NP_001265547 (OMIM: 125853,176885) tyrosine-protei ( 362) 2495 399.1 9.5e-111
NP_536348 (OMIM: 176887) tyrosine-protein phosphat ( 353) 1493 243.3 7.6e-64
NP_536347 (OMIM: 176887) tyrosine-protein phosphat ( 387) 1493 243.3 8.2e-64
XP_016881373 (OMIM: 176887) PREDICTED: tyrosine-pr ( 397) 1493 243.3 8.3e-64
NP_002819 (OMIM: 176887) tyrosine-protein phosphat ( 415) 1493 243.3 8.6e-64
XP_016881374 (OMIM: 176887) PREDICTED: tyrosine-pr ( 386) 1279 210.0 8.5e-54
NP_001295216 (OMIM: 176887) tyrosine-protein phosp ( 386) 1279 210.0 8.5e-54
XP_016881377 (OMIM: 176887) PREDICTED: tyrosine-pr ( 288) 1026 170.6 4.8e-42
XP_016881376 (OMIM: 176887) PREDICTED: tyrosine-pr ( 298) 1026 170.6 4.9e-42
XP_016881375 (OMIM: 176887) PREDICTED: tyrosine-pr ( 316) 1026 170.6 5.1e-42
XP_005258181 (OMIM: 176887) PREDICTED: tyrosine-pr ( 438) 778 132.1 2.7e-30
NP_001193942 (OMIM: 176887) tyrosine-protein phosp ( 410) 757 128.9 2.5e-29
XP_005258182 (OMIM: 176887) PREDICTED: tyrosine-pr ( 420) 757 128.9 2.5e-29
XP_011524009 (OMIM: 176887) PREDICTED: tyrosine-pr ( 259) 747 127.2 5.1e-29
XP_011524007 (OMIM: 176887) PREDICTED: tyrosine-pr ( 409) 749 127.6 5.8e-29
XP_016873574 (OMIM: 600925) PREDICTED: receptor-ty (1321) 680 117.2 2.5e-25
NP_002834 (OMIM: 600925) receptor-type tyrosine-pr (1337) 680 117.2 2.5e-25
XP_016873573 (OMIM: 600925) PREDICTED: receptor-ty (1344) 680 117.2 2.5e-25
XP_016873572 (OMIM: 600925) PREDICTED: receptor-ty (1363) 680 117.2 2.6e-25
XP_016875213 (OMIM: 176882) PREDICTED: receptor-ty (1446) 678 117.0 3.3e-25
NP_001193900 (OMIM: 176882) receptor-type tyrosine (1907) 678 117.0 4.2e-25
NP_001193901 (OMIM: 176882) receptor-type tyrosine (1907) 678 117.0 4.2e-25
NP_002828 (OMIM: 176882) receptor-type tyrosine-pr (1997) 678 117.0 4.3e-25
XP_006719592 (OMIM: 176882) PREDICTED: receptor-ty (2012) 678 117.1 4.3e-25
NP_001317133 (OMIM: 176882) receptor-type tyrosine (2127) 678 117.1 4.5e-25
XP_011536916 (OMIM: 176882) PREDICTED: receptor-ty (2142) 678 117.1 4.6e-25
NP_001103224 (OMIM: 176882) receptor-type tyrosine (2215) 678 117.1 4.7e-25
XP_006719591 (OMIM: 176882) PREDICTED: receptor-ty (2230) 678 117.1 4.7e-25
NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377) 618 107.2 7.4e-23
NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377) 618 107.2 7.4e-23
NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405) 618 107.2 7.9e-23
NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405) 618 107.2 7.9e-23
XP_016860095 (OMIM: 176878) PREDICTED: tyrosine-pr ( 559) 617 107.2 1.1e-22
XP_016860096 (OMIM: 176878) PREDICTED: tyrosine-pr ( 559) 617 107.2 1.1e-22
XP_016860097 (OMIM: 176878) PREDICTED: tyrosine-pr ( 559) 617 107.2 1.1e-22
XP_016860093 (OMIM: 176878) PREDICTED: tyrosine-pr ( 559) 617 107.2 1.1e-22
XP_016860094 (OMIM: 176878) PREDICTED: tyrosine-pr ( 559) 617 107.2 1.1e-22
XP_011509865 (OMIM: 176878) PREDICTED: tyrosine-pr ( 639) 617 107.2 1.3e-22
XP_006719057 (OMIM: 176883) PREDICTED: tyrosine-pr ( 481) 613 106.5 1.5e-22
XP_016860092 (OMIM: 176878) PREDICTED: tyrosine-pr ( 911) 617 107.3 1.7e-22
XP_011509864 (OMIM: 176878) PREDICTED: tyrosine-pr ( 911) 617 107.3 1.7e-22
XP_016860091 (OMIM: 176878) PREDICTED: tyrosine-pr ( 918) 617 107.3 1.7e-22
XP_016860090 (OMIM: 176878) PREDICTED: tyrosine-pr ( 925) 617 107.3 1.7e-22
XP_016860089 (OMIM: 176878) PREDICTED: tyrosine-pr ( 926) 617 107.3 1.7e-22
NP_002821 (OMIM: 176878) tyrosine-protein phosphat ( 926) 617 107.3 1.7e-22
XP_011509862 (OMIM: 176878) PREDICTED: tyrosine-pr ( 933) 617 107.3 1.7e-22
XP_016860088 (OMIM: 176878) PREDICTED: tyrosine-pr ( 933) 617 107.3 1.7e-22
XP_016860087 (OMIM: 176878) PREDICTED: tyrosine-pr ( 933) 617 107.3 1.7e-22
XP_016860086 (OMIM: 176878) PREDICTED: tyrosine-pr ( 940) 617 107.3 1.7e-22
>>NP_002818 (OMIM: 125853,176885) tyrosine-protein phosp (435 aa)
initn: 2995 init1: 2995 opt: 2995 Z-score: 2528.5 bits: 477.0 E(85289): 4.2e-134
Smith-Waterman score: 2995; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KB5 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 IESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLT
370 380 390 400 410 420
430
pF1KB5 AGAYLCYRFLFNSNT
:::::::::::::::
NP_002 AGAYLCYRFLFNSNT
430
>>NP_001265547 (OMIM: 125853,176885) tyrosine-protein ph (362 aa)
initn: 2495 init1: 2495 opt: 2495 Z-score: 2109.3 bits: 399.1 E(85289): 9.5e-111
Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 362 aa overlap (74-435:1-362)
50 60 70 80 90 100
pF1KB5 NRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQK
::::::::::::::::::::::::::::::
NP_001 MEEAQRSYILTQGPLPNTCGHFWEMVWEQK
10 20 30
110 120 130 140 150 160
pF1KB5 SRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 TTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 TFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 DSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKD
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 CPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHAL
280 290 300 310 320 330
410 420 430
pF1KB5 SYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT
::::::::::::::::::::::::::::::::
NP_001 SYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT
340 350 360
>>NP_536348 (OMIM: 176887) tyrosine-protein phosphatase (353 aa)
initn: 1474 init1: 645 opt: 1493 Z-score: 1267.2 bits: 243.3 E(85289): 7.6e-64
Smith-Waterman score: 1498; 66.6% identity (86.6% similar) in 320 aa overlap (3-322:5-315)
10 20 30 40 50
pF1KB5 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIK
.:.:::..: . : .: .::.:. :.: ::::.:.:.::::::::::.::::.:
NP_536 MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGS
:.. .::::::::. .:::::::::::::::::: ::: :::.::...::::::..:: :
NP_536 LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTT
.::::::: ...::.:..:.... :.:::.::::::. :.:::... ::: : ::::::
NP_536 VKCAQYWPT-DDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTT
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 WPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKR
::::::::::::::::::::::::::.:.:::.:.:::::::::::: :.::::.::.:
NP_536 WPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 KDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
: ..::.:::.:::.::::::: :::::::.:.::::: : ::::.: .:::::.::
NP_536 DD---INIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKED
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 LEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAP
: : .: : : . : .::
NP_536 LSPAFDH-----SPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSERPRLT
300 310 320 330 340 350
>>NP_536347 (OMIM: 176887) tyrosine-protein phosphatase (387 aa)
initn: 1474 init1: 645 opt: 1493 Z-score: 1266.6 bits: 243.3 E(85289): 8.2e-64
Smith-Waterman score: 1498; 66.6% identity (86.6% similar) in 320 aa overlap (3-322:5-315)
10 20 30 40 50
pF1KB5 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIK
.:.:::..: . : .: .::.:. :.: ::::.:.:.::::::::::.::::.:
NP_536 MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGS
:.. .::::::::. .:::::::::::::::::: ::: :::.::...::::::..:: :
NP_536 LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTT
.::::::: ...::.:..:.... :.:::.::::::. :.:::... ::: : ::::::
NP_536 VKCAQYWPT-DDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTT
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 WPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKR
::::::::::::::::::::::::::.:.:::.:.:::::::::::: :.::::.::.:
NP_536 WPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 KDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
: ..::.:::.:::.::::::: :::::::.:.::::: : ::::.: .:::::.::
NP_536 DD---INIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKED
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 LEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAP
: : .: : : . : .::
NP_536 LSPAFDH-----SPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRK
300 310 320 330 340 350
>>XP_016881373 (OMIM: 176887) PREDICTED: tyrosine-protei (397 aa)
initn: 1474 init1: 645 opt: 1493 Z-score: 1266.5 bits: 243.3 E(85289): 8.3e-64
Smith-Waterman score: 1498; 66.6% identity (86.6% similar) in 320 aa overlap (3-322:5-315)
10 20 30 40 50
pF1KB5 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIK
.:.:::..: . : .: .::.:. :.: ::::.:.:.::::::::::.::::.:
XP_016 MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGS
:.. .::::::::. .:::::::::::::::::: ::: :::.::...::::::..:: :
XP_016 LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTT
.::::::: ...::.:..:.... :.:::.::::::. :.:::... ::: : ::::::
XP_016 VKCAQYWPT-DDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTT
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 WPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKR
::::::::::::::::::::::::::.:.:::.:.:::::::::::: :.::::.::.:
XP_016 WPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 KDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
: ..::.:::.:::.::::::: :::::::.:.::::: : ::::.: .:::::.::
XP_016 DD---INIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKED
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 LEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAP
: : .: : : . : .::
XP_016 LSPAFDH-----SPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRK
300 310 320 330 340 350
>>NP_002819 (OMIM: 176887) tyrosine-protein phosphatase (415 aa)
initn: 1543 init1: 645 opt: 1493 Z-score: 1266.2 bits: 243.3 E(85289): 8.6e-64
Smith-Waterman score: 1549; 54.3% identity (77.1% similar) in 433 aa overlap (3-434:5-413)
10 20 30 40 50
pF1KB5 MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIK
.:.:::..: . : .: .::.:. :.: ::::.:.:.::::::::::.::::.:
NP_002 MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGS
:.. .::::::::. .:::::::::::::::::: ::: :::.::...::::::..:: :
NP_002 LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTT
.::::::: ...::.:..:.... :.:::.::::::. :.:::... ::: : ::::::
NP_002 VKCAQYWPT-DDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTT
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 WPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKR
::::::::::::::::::::::::::.:.:::.:.:::::::::::: :.::::.::.:
NP_002 WPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 KDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
: ..::.:::.:::.::::::: :::::::.:.::::: : ::::.: .:::::.::
NP_002 DD---INIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKED
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 LEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAP
: : .: : : . : .:: :. ..:: : . :..
NP_002 LSPAFDH-----SPNKIMTEKYNG-------NRIGLEEEKLTGDRC-------TGLSSKM
300 310 320 330
360 370 380 390 400 410
pF1KB5 YGIESMSQDTEVRSRVVGG-SLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVAT
.... .:.:. . :: .. : . . :. . . : ::.:.:..: .
NP_002 QDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWL-YWQPILTKMGFMS
340 350 360 370 380 390
420 430
pF1KB5 VLTAGAYLCYRFLFNSNT
:. .::.. . ..:..:
NP_002 VILVGAFVGWTLFFQQNAL
400 410
>>XP_016881374 (OMIM: 176887) PREDICTED: tyrosine-protei (386 aa)
initn: 1324 init1: 569 opt: 1279 Z-score: 1086.8 bits: 210.0 E(85289): 8.5e-54
Smith-Waterman score: 1330; 54.0% identity (76.2% similar) in 383 aa overlap (53-434:26-384)
30 40 50 60 70 80
pF1KB5 IRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYI
::::.::.. .::::::::. .::::::::
XP_016 MYGKDGKGTNWMDQGDMECRMQEIDDHSRVKLQNAENDYINASLVDIEEAQRSYI
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 LTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKL
:::::::::: ::: :::.::...::::::..:: :.::::::: ...::.:..:....
XP_016 LTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPT-DDQEMLFKETGFSV
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB5 TLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESG
:.:::.::::::. :.:::... ::: : ::::::::::::::::::::::::::::::
XP_016 KLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESG
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB5 SLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQ
::.:.:::.:.:::::::::::: :.::::.::.: : ..::.:::.:::.::::::
XP_016 SLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDD---INIKQVLLNMRKYRMGLIQ
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB5 TADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNG
: :::::::.:.::::: : ::::.: .:::::.::: : .: : : . : .::
XP_016 TPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDH-----SPNKIMTEKYNG
240 250 260 270 280
330 340 350 360 370 380
pF1KB5 KCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGG-SLRG
:. ..:: : . :.. .... .:.:. .
XP_016 -------NRIGLEEEKLTGDRC-------TGLSSKMQDTMEENSESALRKRIREDRKATT
290 300 310 320 330
390 400 410 420 430
pF1KB5 AQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT
:: .. : . . :. . . : ::.:.:..: .:. .::.. . ..:..:
XP_016 AQKVQQMKQRLNENERKRKRWL-YWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
340 350 360 370 380
>>NP_001295216 (OMIM: 176887) tyrosine-protein phosphata (386 aa)
initn: 1324 init1: 569 opt: 1279 Z-score: 1086.8 bits: 210.0 E(85289): 8.5e-54
Smith-Waterman score: 1330; 54.0% identity (76.2% similar) in 383 aa overlap (53-434:26-384)
30 40 50 60 70 80
pF1KB5 IRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYI
::::.::.. .::::::::. .::::::::
NP_001 MYGKDGKGTNWMDQGDMECRMQEIDDHSRVKLQNAENDYINASLVDIEEAQRSYI
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 LTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKL
:::::::::: ::: :::.::...::::::..:: :.::::::: ...::.:..:....
NP_001 LTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPT-DDQEMLFKETGFSV
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB5 TLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESG
:.:::.::::::. :.:::... ::: : ::::::::::::::::::::::::::::::
NP_001 KLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESG
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB5 SLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQ
::.:.:::.:.:::::::::::: :.::::.::.: : ..::.:::.:::.::::::
NP_001 SLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDD---INIKQVLLNMRKYRMGLIQ
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB5 TADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNG
: :::::::.:.::::: : ::::.: .:::::.::: : .: : : . : .::
NP_001 TPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDH-----SPNKIMTEKYNG
240 250 260 270 280
330 340 350 360 370 380
pF1KB5 KCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGG-SLRG
:. ..:: : . :.. .... .:.:. .
NP_001 -------NRIGLEEEKLTGDRC-------TGLSSKMQDTMEENSESALRKRIREDRKATT
290 300 310 320 330
390 400 410 420 430
pF1KB5 AQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT
:: .. : . . :. . . : ::.:.:..: .:. .::.. . ..:..:
NP_001 AQKVQQMKQRLNENERKRKRWL-YWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
340 350 360 370 380
>>XP_016881377 (OMIM: 176887) PREDICTED: tyrosine-protei (288 aa)
initn: 1002 init1: 569 opt: 1026 Z-score: 875.9 bits: 170.6 E(85289): 4.8e-42
Smith-Waterman score: 1026; 66.7% identity (86.2% similar) in 225 aa overlap (98-322:1-216)
70 80 90 100 110 120
pF1KB5 NASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQ
:::.::...::::::..:: :.:::::::
XP_016 MVWQQKTKAVVMLNRIVEKESVKCAQYWPT
10 20 30
130 140 150 160 170 180
pF1KB5 KEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPES
...::.:..:.... :.:::.::::::. :.:::... ::: : :::::::::::::::
XP_016 -DDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPES
40 50 60 70 80
190 200 210 220 230 240
pF1KB5 PASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIK
:::::::::::::::::.:.:::.:.:::::::::::: :.::::.::.: : ..::
XP_016 PASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDD---INIK
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB5 KVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIP
.:::.:::.::::::: :::::::.:.::::: : ::::.: .:::::.::: : .:
XP_016 QVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDH--
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB5 PPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQD
: : . : .::
XP_016 ---SPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
210 220 230 240 250 260
>>XP_016881376 (OMIM: 176887) PREDICTED: tyrosine-protei (298 aa)
initn: 1002 init1: 569 opt: 1026 Z-score: 875.7 bits: 170.6 E(85289): 4.9e-42
Smith-Waterman score: 1026; 66.7% identity (86.2% similar) in 225 aa overlap (98-322:1-216)
70 80 90 100 110 120
pF1KB5 NASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQ
:::.::...::::::..:: :.:::::::
XP_016 MVWQQKTKAVVMLNRIVEKESVKCAQYWPT
10 20 30
130 140 150 160 170 180
pF1KB5 KEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPES
...::.:..:.... :.:::.::::::. :.:::... ::: : :::::::::::::::
XP_016 -DDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPES
40 50 60 70 80
190 200 210 220 230 240
pF1KB5 PASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIK
:::::::::::::::::.:.:::.:.:::::::::::: :.::::.::.: : ..::
XP_016 PASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDD---INIK
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB5 KVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIP
.:::.:::.::::::: :::::::.:.::::: : ::::.: .:::::.::: : .:
XP_016 QVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDH--
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB5 PPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQD
: : . : .::
XP_016 ---SPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
210 220 230 240 250 260
435 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:56:55 2016 done: Thu Nov 3 17:56:56 2016
Total Scan time: 9.760 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]