FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5678, 778 aa 1>>>pF1KB5678 778 - 778 aa - 778 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.2397+/-0.000551; mu= -11.8684+/- 0.034 mean_var=467.8871+/-98.742, 0's: 0 Z-trim(119.4): 179 B-trim: 653 in 1/55 Lambda= 0.059293 statistics sampled from 33122 (33312) to 33122 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.391), width: 16 Scan time: 13.130 The best scores are: opt bits E(85289) NP_008917 (OMIM: 300224) melanoma-associated antig ( 778) 5454 482.0 4.2e-135 XP_016885469 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 5454 482.0 4.2e-135 XP_011529137 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 5454 482.0 4.2e-135 NP_001005332 (OMIM: 300224) melanoma-associated an ( 778) 5454 482.0 4.2e-135 XP_016885467 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 5454 482.0 4.2e-135 XP_016885468 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 5454 482.0 4.2e-135 NP_001005333 (OMIM: 300224) melanoma-associated an ( 834) 5347 472.9 2.5e-132 NP_001092270 (OMIM: 300702) melanoma-associated an ( 739) 1493 143.1 4e-33 XP_016885365 (OMIM: 300765) PREDICTED: melanoma-as ( 739) 1493 143.1 4e-33 NP_803881 (OMIM: 300765) melanoma-associated antig ( 739) 1493 143.1 4e-33 XP_011529124 (OMIM: 300765) PREDICTED: melanoma-as ( 739) 1493 143.1 4e-33 NP_110428 (OMIM: 300765) melanoma-associated antig ( 741) 1493 143.1 4e-33 NP_001258992 (OMIM: 300702) melanoma-associated an ( 741) 1493 143.1 4e-33 NP_001258991 (OMIM: 300702) melanoma-associated an ( 741) 1493 143.1 4e-33 XP_006724671 (OMIM: 300765) PREDICTED: melanoma-as ( 741) 1493 143.1 4e-33 NP_803879 (OMIM: 300765) melanoma-associated antig ( 741) 1493 143.1 4e-33 XP_006724670 (OMIM: 300765) PREDICTED: melanoma-as ( 741) 1493 143.1 4e-33 NP_001258113 (OMIM: 300132) trophinin isoform 7 [H (1034) 1331 129.4 7.6e-29 XP_016885257 (OMIM: 300132) PREDICTED: trophinin i (1387) 1331 129.5 9.4e-29 XP_011529116 (OMIM: 300132) PREDICTED: trophinin i (1387) 1331 129.5 9.4e-29 XP_011529113 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 XP_006724663 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 XP_011529115 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 XP_016885256 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 XP_011529111 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 NP_001034794 (OMIM: 300132) trophinin isoform 5 [H (1431) 1331 129.5 9.6e-29 XP_011529110 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 XP_011529114 (OMIM: 300132) PREDICTED: trophinin i (1431) 1331 129.5 9.6e-29 NP_803182 (OMIM: 300470,300971) melanoma-associate ( 606) 1208 118.7 7.6e-26 NP_957516 (OMIM: 300470,300971) melanoma-associate ( 606) 1208 118.7 7.6e-26 NP_055414 (OMIM: 300470,300971) melanoma-associate ( 606) 1208 118.7 7.6e-26 NP_001258112 (OMIM: 300132) trophinin isoform 6 [H ( 962) 1147 113.6 3.9e-24 NP_808225 (OMIM: 300132) trophinin isoform 4 [Homo ( 309) 1120 110.9 8.6e-24 XP_016885262 (OMIM: 300132) PREDICTED: trophinin i ( 662) 1120 111.2 1.5e-23 XP_016885261 (OMIM: 300132) PREDICTED: trophinin i ( 662) 1120 111.2 1.5e-23 NP_808224 (OMIM: 300132) trophinin isoform 2 [Homo ( 706) 1120 111.2 1.6e-23 XP_016885258 (OMIM: 300132) PREDICTED: trophinin i ( 706) 1120 111.2 1.6e-23 NP_057241 (OMIM: 300132) trophinin isoform 2 [Homo ( 706) 1120 111.2 1.6e-23 XP_016885259 (OMIM: 300132) PREDICTED: trophinin i ( 706) 1120 111.2 1.6e-23 XP_016885260 (OMIM: 300132) PREDICTED: trophinin i ( 706) 1120 111.2 1.6e-23 NP_001258990 (OMIM: 300702) melanoma-associated an ( 757) 830 86.4 4.8e-16 NP_001229291 (OMIM: 300765) melanoma-associated an ( 757) 830 86.4 4.8e-16 XP_011529125 (OMIM: 300765) PREDICTED: melanoma-as ( 647) 821 85.6 7.3e-16 NP_061939 (OMIM: 176270,605283,615547) MAGE-like p (1249) 741 79.0 1.4e-13 NP_065983 (OMIM: 300759) melanoma-associated antig ( 957) 704 75.7 1e-12 NP_619649 (OMIM: 608243) non-structural maintenanc ( 304) 689 74.0 1.1e-12 XP_006726908 (OMIM: 300765) PREDICTED: melanoma-as ( 185) 675 72.6 1.7e-12 XP_005276770 (OMIM: 300765) PREDICTED: melanoma-as ( 187) 675 72.6 1.7e-12 NP_071432 (OMIM: 609267) melanoma-associated antig ( 307) 676 72.9 2.3e-12 NP_002478 (OMIM: 176270,602117) necdin [Homo sapie ( 321) 602 66.6 1.9e-10 >>NP_008917 (OMIM: 300224) melanoma-associated antigen D (778 aa) initn: 5454 init1: 5454 opt: 5454 Z-score: 2546.6 bits: 482.0 E(85289): 4.2e-135 Smith-Waterman score: 5454; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778) 10 20 30 40 50 60 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 730 740 750 760 770 >>XP_016885469 (OMIM: 300224) PREDICTED: melanoma-associ (778 aa) initn: 5454 init1: 5454 opt: 5454 Z-score: 2546.6 bits: 482.0 E(85289): 4.2e-135 Smith-Waterman score: 5454; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778) 10 20 30 40 50 60 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 730 740 750 760 770 >>XP_011529137 (OMIM: 300224) PREDICTED: melanoma-associ (778 aa) initn: 5454 init1: 5454 opt: 5454 Z-score: 2546.6 bits: 482.0 E(85289): 4.2e-135 Smith-Waterman score: 5454; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778) 10 20 30 40 50 60 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 730 740 750 760 770 >>NP_001005332 (OMIM: 300224) melanoma-associated antige (778 aa) initn: 5454 init1: 5454 opt: 5454 Z-score: 2546.6 bits: 482.0 E(85289): 4.2e-135 Smith-Waterman score: 5454; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778) 10 20 30 40 50 60 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 730 740 750 760 770 >>XP_016885467 (OMIM: 300224) PREDICTED: melanoma-associ (778 aa) initn: 5454 init1: 5454 opt: 5454 Z-score: 2546.6 bits: 482.0 E(85289): 4.2e-135 Smith-Waterman score: 5454; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778) 10 20 30 40 50 60 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 730 740 750 760 770 >>XP_016885468 (OMIM: 300224) PREDICTED: melanoma-associ (778 aa) initn: 5454 init1: 5454 opt: 5454 Z-score: 2546.6 bits: 482.0 E(85289): 4.2e-135 Smith-Waterman score: 5454; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778) 10 20 30 40 50 60 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYIL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEE 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE 730 740 750 760 770 >>NP_001005333 (OMIM: 300224) melanoma-associated antige (834 aa) initn: 5347 init1: 5347 opt: 5347 Z-score: 2496.7 bits: 472.9 E(85289): 2.5e-132 Smith-Waterman score: 5347; 100.0% identity (100.0% similar) in 763 aa overlap (16-778:72-834) 10 20 30 40 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQA :::::::::::::::::::::::::::::: NP_001 TLCDPPYSQLRDPPAVLSCYCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQA 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB5 TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPN 110 120 130 140 150 160 110 120 130 140 150 160 pF1KB5 TQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQ 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB5 SLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGAT 230 240 250 260 270 280 230 240 250 260 270 280 pF1KB5 AQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQ 290 300 310 320 330 340 290 300 310 320 330 340 pF1KB5 NPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWP 350 360 370 380 390 400 350 360 370 380 390 400 pF1KB5 NPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWP 410 420 430 440 450 460 410 420 430 440 450 460 pF1KB5 LPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQP 470 480 490 500 510 520 470 480 490 500 510 520 pF1KB5 RDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFG 530 540 550 560 570 580 530 540 550 560 570 580 pF1KB5 IQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEA 590 600 610 620 630 640 590 600 610 620 630 640 pF1KB5 LRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKM 650 660 670 680 690 700 650 660 670 680 690 700 pF1KB5 KVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPW 710 720 730 740 750 760 710 720 730 740 750 760 pF1KB5 SWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANF 770 780 790 800 810 820 770 pF1KB5 AANFGAIGFFWVE ::::::::::::: NP_001 AANFGAIGFFWVE 830 >>NP_001092270 (OMIM: 300702) melanoma-associated antige (739 aa) initn: 1781 init1: 1457 opt: 1493 Z-score: 715.7 bits: 143.1 E(85289): 4e-33 Smith-Waterman score: 1516; 41.1% identity (60.6% similar) in 771 aa overlap (8-764:63-711) 10 20 30 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQIS : :: .. : .. .: :::.::.:.. NP_001 GNDYEEFGAFGGYGTLTSFDIHILRAFGSLGPGLRILSNEPWELENPVLAQTLVEALQLD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB5 EAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQA .:. ::: . . .. ..:. : ...::::: .::. :. . : NP_001 PETLANE-TAARAANVARAAASNRAA--RAAAAAAR--TAFSQVVASHR---------VA 100 110 120 130 100 110 120 130 140 pF1KB5 HNAKDVPNTQPKA-AFKSQNATPKGPNAAYDFSQAATTGELAA-------NKSEMAFKAQ . .::: . : ..:. ::. : :. . :: .:...:: .:. . :: NP_001 TPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQ 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB5 NATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQ .:.:. ::... :::. : .. .::.: : . ::. :: .. . :: NP_001 EAATE-GPSSACAFSQAPCAREVDANRPSTAFLGQNDVFDF------TQPAGVSGMAF-- 200 210 220 230 240 210 220 230 240 250 260 pF1KB5 ADIETDPGISEPDGATAQTSA-DGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRA : ..: : :: .: .: .: .:: . . NP_001 ------PRPKRP--APAQEAATEGPSA-------------------------ASGVPQTG 250 260 270 270 280 290 300 310 320 pF1KB5 PLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQT : : .: : ::.. ..: .: : .: :: .: . :... NP_001 P---GREVAATRPKTTKSG-----KALAKT--RWVEP---QNVVAAAAAKAKMATSI--- 280 290 300 310 320 330 340 350 360 370 380 pF1KB5 PPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQT :.: : .. : .. : : .: NP_001 ----------------PEP---------------EGAAA---ATAQHSAEPWARMGGKRT 330 340 390 400 410 420 430 440 pF1KB5 PPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNL . . .... . : .:: : :. : .: : : . NP_001 KKSKHLDDEYESSEEERETP--AVPPTWR-------------ASQPSLTVRAQLAPRPPM 350 360 370 380 390 450 460 470 480 490 500 pF1KB5 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV : .. :.. ::.:.::::::::::::::.::: :.::::..::.:.:::: . NP_001 APR-SQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEH 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB5 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILG .::::::: ..:::::::.:::::::::::::. : .: : .:: :::::.:.::::::: NP_001 FPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSARLLGKTKDTPRLSLLLVILG 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB5 VIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPP ::::::::::::::::::::::::::::::.:::::::.: .:::::::.:...:::::: NP_001 VIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPP 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB5 EYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARA :::::::::. ::::::.::::::. :.::::.: :.:.::.:.:. ..:. :: .::: NP_001 EYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARA 580 590 600 610 620 630 690 700 710 720 730 740 pF1KB5 EARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQ-----NAR . :..:.:::::. : ::::::. :::::::.::::: :.::::.::::::: : NP_001 QMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRA 640 650 660 670 680 690 750 760 770 pF1KB5 SRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE .: :: : .: ::.. NP_001 NRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNAARAGASFFSWIQ 700 710 720 730 >>XP_016885365 (OMIM: 300765) PREDICTED: melanoma-associ (739 aa) initn: 1781 init1: 1457 opt: 1493 Z-score: 715.7 bits: 143.1 E(85289): 4e-33 Smith-Waterman score: 1516; 41.1% identity (60.6% similar) in 771 aa overlap (8-764:63-711) 10 20 30 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQIS : :: .. : .. .: :::.::.:.. XP_016 GNDYEEFGAFGGYGTLTSFDIHILRAFGSLGPGLRILSNEPWELENPVLAQTLVEALQLD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB5 EAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQA .:. ::: . . .. ..:. : ...::::: .::. :. . : XP_016 PETLANE-TAARAANVARAAASNRAA--RAAAAAAR--TAFSQVVASHR---------VA 100 110 120 130 100 110 120 130 140 pF1KB5 HNAKDVPNTQPKA-AFKSQNATPKGPNAAYDFSQAATTGELAA-------NKSEMAFKAQ . .::: . : ..:. ::. : :. . :: .:...:: .:. . :: XP_016 TPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQ 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB5 NATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQ .:.:. ::... :::. : .. .::.: : . ::. :: .. . :: XP_016 EAATE-GPSSACAFSQAPCAREVDANRPSTAFLGQNDVFDF------TQPAGVSGMAF-- 200 210 220 230 240 210 220 230 240 250 260 pF1KB5 ADIETDPGISEPDGATAQTSA-DGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRA : ..: : :: .: .: .: .:: . . XP_016 ------PRPKRP--APAQEAATEGPSA-------------------------ASGVPQTG 250 260 270 270 280 290 300 310 320 pF1KB5 PLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQT : : .: : ::.. ..: .: : .: :: .: . :... XP_016 P---GREVAATRPKTTKSG-----KALAKT--RWVEP---QNVVAAAAAKAKMATSI--- 280 290 300 310 320 330 340 350 360 370 380 pF1KB5 PPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQT :.: : .. : .. : : .: XP_016 ----------------PEP---------------EGAAA---ATAQHSAEPWARMGGKRT 330 340 390 400 410 420 430 440 pF1KB5 PPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNL . . .... . : .:: : :. : .: : : . XP_016 KKSKHLDDEYESSEEERETP--AVPPTWR-------------ASQPSLTVRAQLAPRPPM 350 360 370 380 390 450 460 470 480 490 500 pF1KB5 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV : .. :.. ::.:.::::::::::::::.::: :.::::..::.:.:::: . XP_016 APR-SQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEH 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB5 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILG .::::::: ..:::::::.:::::::::::::. : .: : .:: :::::.:.::::::: XP_016 FPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSARLLGKTKDTPRLSLLLVILG 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB5 VIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPP ::::::::::::::::::::::::::::::.:::::::.: .:::::::.:...:::::: XP_016 VIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPP 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB5 EYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARA :::::::::. ::::::.::::::. :.::::.: :.:.::.:.:. ..:. :: .::: XP_016 EYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARA 580 590 600 610 620 630 690 700 710 720 730 740 pF1KB5 EARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQ-----NAR . :..:.:::::. : ::::::. :::::::.::::: :.::::.::::::: : XP_016 QMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRA 640 650 660 670 680 690 750 760 770 pF1KB5 SRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE .: :: : .: ::.. XP_016 NRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNAARAGASFFSWIQ 700 710 720 730 >>NP_803881 (OMIM: 300765) melanoma-associated antigen D (739 aa) initn: 1781 init1: 1457 opt: 1493 Z-score: 715.7 bits: 143.1 E(85289): 4e-33 Smith-Waterman score: 1516; 41.1% identity (60.6% similar) in 771 aa overlap (8-764:63-711) 10 20 30 pF1KB5 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQIS : :: .. : .. .: :::.::.:.. NP_803 GNDYEEFGAFGGYGTLTSFDIHILRAFGSLGPGLRILSNEPWELENPVLAQTLVEALQLD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB5 EAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQA .:. ::: . . .. ..:. : ...::::: .::. :. . : NP_803 PETLANE-TAARAANVARAAASNRAA--RAAAAAAR--TAFSQVVASHR---------VA 100 110 120 130 100 110 120 130 140 pF1KB5 HNAKDVPNTQPKA-AFKSQNATPKGPNAAYDFSQAATTGELAA-------NKSEMAFKAQ . .::: . : ..:. ::. : :. . :: .:...:: .:. . :: NP_803 TPQVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQ 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB5 NATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQ .:.:. ::... :::. : .. .::.: : . ::. :: .. . :: NP_803 EAATE-GPSSACAFSQAPCAREVDANRPSTAFLGQNDVFDF------TQPAGVSGMAF-- 200 210 220 230 240 210 220 230 240 250 260 pF1KB5 ADIETDPGISEPDGATAQTSA-DGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRA : ..: : :: .: .: .: .:: . . NP_803 ------PRPKRP--APAQEAATEGPSA-------------------------ASGVPQTG 250 260 270 270 280 290 300 310 320 pF1KB5 PLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQT : : .: : ::.. ..: .: : .: :: .: . :... NP_803 P---GREVAATRPKTTKSG-----KALAKT--RWVEP---QNVVAAAAAKAKMATSI--- 280 290 300 310 320 330 340 350 360 370 380 pF1KB5 PPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQT :.: : .. : .. : : .: NP_803 ----------------PEP---------------EGAAA---ATAQHSAEPWARMGGKRT 330 340 390 400 410 420 430 440 pF1KB5 PPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNL . . .... . : .:: : :. : .: : : . NP_803 KKSKHLDDEYESSEEERETP--AVPPTWR-------------ASQPSLTVRAQLAPRPPM 350 360 370 380 390 450 460 470 480 490 500 pF1KB5 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV : .. :.. ::.:.::::::::::::::.::: :.::::..::.:.:::: . NP_803 APR-SQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEH 400 410 420 430 440 450 510 520 530 540 550 560 pF1KB5 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILG .::::::: ..:::::::.:::::::::::::. : .: : .:: :::::.:.::::::: NP_803 FPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRDSSARLLGKTKDTPRLSLLLVILG 460 470 480 490 500 510 570 580 590 600 610 620 pF1KB5 VIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPP ::::::::::::::::::::::::::::::.:::::::.: .:::::::.:...:::::: NP_803 VIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPP 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB5 EYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARA :::::::::. ::::::.::::::. :.::::.: :.:.::.:.:. ..:. :: .::: NP_803 EYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARA 580 590 600 610 620 630 690 700 710 720 730 740 pF1KB5 EARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQ-----NAR . :..:.:::::. : ::::::. :::::::.::::: :.::::.::::::: : NP_803 QMRAQMNIGDEALIGRWSWDDIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRA 640 650 660 670 680 690 750 760 770 pF1KB5 SRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE .: :: : .: ::.. NP_803 NRRATWRAGVSSGTNGGASTSVLDGPSTSSTIRTRNAARAGASFFSWIQ 700 710 720 730 778 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:45:41 2016 done: Thu Nov 3 22:45:43 2016 Total Scan time: 13.130 Total Display time: 0.250 Function used was FASTA [36.3.4 Apr, 2011]