FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5682, 552 aa 1>>>pF1KB5682 552 - 552 aa - 552 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1059+/-0.000901; mu= 6.8919+/- 0.054 mean_var=180.9090+/-36.388, 0's: 0 Z-trim(111.9): 20 B-trim: 0 in 0/53 Lambda= 0.095355 statistics sampled from 12729 (12744) to 12729 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.391), width: 16 Scan time: 3.770 The best scores are: opt bits E(32554) CCDS11950.1 SMAD4 gene_id:4089|Hs108|chr18 ( 552) 3833 539.7 3.4e-153 CCDS9360.1 SMAD9 gene_id:4093|Hs108|chr13 ( 430) 493 80.2 5.7e-15 CCDS45032.1 SMAD9 gene_id:4093|Hs108|chr13 ( 467) 493 80.2 6.1e-15 CCDS75308.1 SMAD5 gene_id:4090|Hs108|chr5 ( 465) 485 79.1 1.3e-14 CCDS10222.1 SMAD3 gene_id:4088|Hs108|chr15 ( 425) 472 77.3 4.2e-14 CCDS3765.1 SMAD1 gene_id:4086|Hs108|chr4 ( 465) 471 77.2 5e-14 >>CCDS11950.1 SMAD4 gene_id:4089|Hs108|chr18 (552 aa) initn: 3833 init1: 3833 opt: 3833 Z-score: 2863.9 bits: 539.7 E(32554): 3.4e-153 Smith-Waterman score: 3833; 100.0% identity (100.0% similar) in 552 aa overlap (1-552:1-552) 10 20 30 40 50 60 pF1KB5 MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 YWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 AISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL 490 500 510 520 530 540 550 pF1KB5 HTMPIADPQPLD :::::::::::: CCDS11 HTMPIADPQPLD 550 >>CCDS9360.1 SMAD9 gene_id:4093|Hs108|chr13 (430 aa) initn: 860 init1: 231 opt: 493 Z-score: 382.2 bits: 80.2 E(32554): 5.7e-15 Smith-Waterman score: 887; 35.4% identity (55.2% similar) in 542 aa overlap (7-543:3-419) 10 20 30 40 50 pF1KB5 MDNMSITNTPTSNDACLS--IVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLI ..:: :. .. :. :. .:: : : .:..:..:::::::.:: .: : CCDS93 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELE 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKN-ELKHVKYCQY :.. : .::::::: :.:::::::. :::.::::: :.::::::... ::: .. :.. CCDS93 RALSCPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGH : : ::.:::::.:: .: . CCDS93 PFGSKQKEVCINPYHYRRVETPVL------------------------------------ 120 130 180 190 200 210 220 230 pF1KB5 SIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGL :: .:.: .:. . :.. . . . ::. ::: : CCDS93 -------PP-------------VLVPRHSEYN-----PQLSLLAKFRSASL----HSEPL 140 150 160 170 240 250 260 270 280 290 pF1KB5 L-QIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPP . . :. :. :: . :. : : . :.: :..:. : . .. :: CCDS93 MPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASY--PHSPGSPSEPESPYQH------ 180 190 200 210 220 300 310 320 330 340 350 pF1KB5 HPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDP . . :: : :..:::.::.:.. .:::::.. : : .::..:: CCDS93 --SDFRPVCYE-----------EPQHWCSVAYYELNNRVGETFQASSRS--VLIDGFTDP 230 240 250 260 360 370 380 390 400 410 pF1KB5 SGG-DRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLD :.. .::::: ::::.:. .:: .: ::::::.: : :.:...:.:: ..:::: . CCDS93 SNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECVSDSSIFVQSRNCN 270 280 290 300 310 320 420 430 440 450 460 470 pF1KB5 REAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSV . : :. .: :: . .:::. .: : : .. .. : CCDS93 YQHGFHPA-TVCKIPSGCSLKVFN--------NQLFAQLLAQSVHHGFEV---------- 330 340 350 360 480 490 500 510 520 530 pF1KB5 GGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQL : .: ..: .::::::::: .: ::.. :::::::::: :: CCDS93 ----------------VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 370 380 390 400 410 540 550 pF1KB5 LDEVLHTMPIADPQPLD ::.:: : CCDS93 LDKVLTQMGSPHNPISSVS 420 430 >>CCDS45032.1 SMAD9 gene_id:4093|Hs108|chr13 (467 aa) initn: 741 init1: 231 opt: 493 Z-score: 381.7 bits: 80.2 E(32554): 6.1e-15 Smith-Waterman score: 947; 36.4% identity (57.8% similar) in 550 aa overlap (7-543:3-456) 10 20 30 40 50 pF1KB5 MDNMSITNTPTSNDACLS--IVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLI ..:: :. .. :. :. .:: : : .:..:..:::::::.:: .: : CCDS45 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELE 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKN-ELKHVKYCQY :.. : .::::::: :.:::::::. :::.::::: :.::::::... ::: .. :.. CCDS45 RALSCPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 AFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGH : : ::.:::::.:: .: . : .. . ... : :: .. . CCDS45 PFGSKQKEVCINPYHYRRVETPVL-----------PPVLVPRHS---EYNPQLSLLAKFR 120 130 140 150 160 180 190 200 210 220 pF1KB5 SIQTIQHP--PSNRASTETYSTP--ALLAPSESNATS----TANFPNIPVASTSQPASIL : . ..: : : . .... : . : :: :.: : ::..:. : .: :.: : CCDS45 SASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSP-GSPSEPESPY 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 GGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHN-STTTWTGSRTAPYTPNLPHHQNGHL .:: . . : : :: . .. : .:. : .. CCDS45 --QHS-----VDTPPLP-------------YHATEASETQSGQ---PV--------DATA 230 240 290 300 310 320 330 340 pF1KB5 QHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIV ..: . : . :: : :..:::.::.:.. .:::::.. : : CCDS45 DRHVVLSIPNGDFRPVCYE-----------EPQHWCSVAYYELNNRVGETFQASSRS--V 250 260 270 280 290 350 360 370 380 390 400 pF1KB5 TVDGYVDPSGG-DRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAV .::..:::.. .::::: ::::.:. .:: .: ::::::.: : :.:...:.:: .. CCDS45 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECVSDSSI 300 310 320 330 340 350 410 420 430 440 450 460 pF1KB5 FVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAG :::: . . : :. .: :: . .:::. .: : : .. .. : CCDS45 FVQSRNCNYQHGFHPA-TVCKIPSGCSLKVFN--------NQLFAQLLAQSVHHGFEV-- 360 370 380 390 400 470 480 490 500 510 520 pF1KB5 NIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEI : .: ..: .::::::::: .: ::.. ::::::: CCDS45 ------------------------VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 410 420 430 440 530 540 550 pF1KB5 HLHRALQLLDEVLHTMPIADPQPLD ::: :: ::.:: : CCDS45 HLHGPLQWLDKVLTQMGSPHNPISSVS 450 460 >>CCDS75308.1 SMAD5 gene_id:4090|Hs108|chr5 (465 aa) initn: 701 init1: 232 opt: 485 Z-score: 375.8 bits: 79.1 E(32554): 1.3e-14 Smith-Waterman score: 937; 36.9% identity (56.5% similar) in 531 aa overlap (20-543:15-454) 10 20 30 40 50 60 pF1KB5 MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA :. :. .:: : : .:..:...::::::.:: .. : : CCDS75 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKA 10 20 30 40 50 70 80 90 100 110 pF1KB5 ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKN-ELKHVKYCQYAF ... : .::::::: :.:::::::. :::.::::: :.::::::... ::: . :.. : CCDS75 LSSPG-QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 DLKCDSVCVNPYHYERVVSPGID--LSGLTLQSNAPSSMMVK-DEYVHDFEGQPSLSTEG : ::.:::::.:: :: . : . : :..:. . :. .:. .: CCDS75 GSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 HSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEG :. : :.: :: :.:. . .: : ::.. : : CCDS75 DSF----HQPNN--------TPFPLSPN-------SPYPPSP-ASSTYPNS--------- 180 190 200 240 250 260 270 280 290 pF1KB5 LLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPP .::: : . : :: : : : : :. .. :: CCDS75 --PASSGPGSPFQLPADTPPPA-----------------YMP--PDDQMGQ-DNSQPMDT 210 220 230 240 300 310 320 330 340 350 pF1KB5 HPGHYWPVHNELAFQP--PISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYV . . .. . :.. . :..::::.:.:.. .:::.:.. :. : :::.. CCDS75 SNNMIPQIMPSISSRDVQPVA-YEEPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFT 250 260 270 280 290 300 360 370 380 390 400 410 pF1KB5 DPSGG-DRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYY :::.. .::::: ::::.:. .:: .: ::::::.: : :.:...:::: ..:::: CCDS75 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRN 310 320 330 340 350 420 430 440 450 460 470 pF1KB5 LDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPG . . : : .: :: : .:.:. : :. :... : CCDS75 CNFHHGFHP-TTVCKIPSSCSLKIFN-NQEFAQLLAQSVNHGFEA--------------- 360 370 380 390 400 480 490 500 510 520 530 pF1KB5 SVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRAL : .: ..: .::::::::: .: ::.. :::::::::: : CCDS75 ------------------VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPL 410 420 430 440 540 550 pF1KB5 QLLDEVLHTMPIADPQPLD : ::.:: : CCDS75 QWLDKVLTQMGSPLNPISSVS 450 460 >>CCDS10222.1 SMAD3 gene_id:4088|Hs108|chr15 (425 aa) initn: 766 init1: 229 opt: 472 Z-score: 366.6 bits: 77.3 E(32554): 4.2e-14 Smith-Waterman score: 938; 37.7% identity (58.1% similar) in 530 aa overlap (19-543:11-414) 10 20 30 40 50 pF1KB5 MDNMSITNTPTSNDACLSIVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSL ::. :. ..: :. : . ..:..::::::: : .:: : CCDS10 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLK-KTGQLDEL 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 ITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKN-ELKHVKYCQ ::::.... .::.:: :.:::::::. :::.::::: :::::::::.. ::. .. :. CCDS10 EKAITTQNVN-TKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 YAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEG .::..: : ::::::::.:: .: . . ... :. .: : :. . CCDS10 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPA----------EF---PPLDDYS 120 130 140 150 180 190 200 210 220 230 pF1KB5 HSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEG ::: : : .::: . .: : CCDS10 HSI------PEN-----------------------TNFP-----AGIEPQS--------- 160 170 240 250 260 270 280 290 pF1KB5 LLQIASGPQPGQ-QQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMP .: : :: ...: :.. :. . . .:: ::: CCDS10 --NIPETPPPGYLSEDGETSD----HQMNHSMDAGS------PNLS-------------- 180 190 200 300 310 320 330 340 350 pF1KB5 PHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVD :.: :.::.: .:: .:: .::::.:.:.. .:::::. .: : .::::..: CCDS10 PNPMS--PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTD 210 220 230 240 250 260 360 370 380 390 400 410 pF1KB5 PSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLD ::...::::: ::::.:. :.: .: :::.::.: : :.:...:::: :.:::: . CCDS10 PSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCN 270 280 290 300 310 320 420 430 440 450 460 470 pF1KB5 REAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSV .. : :. .: :: :. .:.:. .:. :. : .. : CCDS10 QRYGWHPA-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQ-------------- 330 340 350 480 490 500 510 520 530 pF1KB5 GGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQL :. .: .: :.: .::::::::: .: ::.. ::::::.::. :: CCDS10 -GFE-----------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 360 370 380 390 400 540 550 pF1KB5 LDEVLHTMPIADPQPLD ::.:: : CCDS10 LDKVLTQMGSPSIRCSSVS 410 420 >>CCDS3765.1 SMAD1 gene_id:4086|Hs108|chr4 (465 aa) initn: 696 init1: 225 opt: 471 Z-score: 365.4 bits: 77.2 E(32554): 5e-14 Smith-Waterman score: 938; 36.3% identity (58.0% similar) in 529 aa overlap (20-543:14-454) 10 20 30 40 50 60 pF1KB5 MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA :. :. .:: : : .:..:...::::::.:: .. : : CCDS37 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKA 10 20 30 40 50 70 80 90 100 110 pF1KB5 ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKN-ELKHVKYCQYAF .. : .::.:::: :.:::::::. :::.::::: :.::::::... ::: .. :.. : CCDS37 LSCPG-QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 DLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSI : ::.:::::.:: :: . : .. . ... : :: .. ... CCDS37 GSKQKEVCINPYHYKRVESPVL-----------PPVLVPRHS---EYNPQHSLLAQFRNL 120 130 140 150 180 190 200 210 220 230 pF1KB5 -QTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLL :. : : : . .... : .. ::. : ..: : : :: : CCDS37 GQNEPHMPLNATFPDSFQQP-----------NSHPFPHSP--NSSYPNS--PGSSSSTYP 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 QIASGPQPGQ--QQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPP . .. .::. :. . : :: .. : ::. :. :. ::.: CCDS37 HSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ--PMDTNM---------MAPPLPS 210 220 230 240 250 300 310 320 330 340 350 pF1KB5 HPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDP . :. : . :..::::.:.:.. .:::.:.. :. : :::..:: CCDS37 EI-------NRGDVQA--VAYEEPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDP 260 270 280 290 300 360 370 380 390 400 410 pF1KB5 SGG-DRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLD :.. .::::: ::::.:. .:: .: ::::::.: : :.:...:::: ..:::: . CCDS37 SNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCN 310 320 330 340 350 360 420 430 440 450 460 470 pF1KB5 REAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSV . : : .: :: . .:.:. : :. :... CCDS37 YHHGFHP-TTVCKIPSGCSLKIFN-NQEFAQLLAQSVNH--------------------- 370 380 390 480 490 500 510 520 530 pF1KB5 GGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQL :. : .: ..: .::::::::: .: ::.. :::::::::: :: CCDS37 -GFET-----------VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 400 410 420 430 440 540 550 pF1KB5 LDEVLHTMPIADPQPLD ::.:: : CCDS37 LDKVLTQMGSPHNPISSVS 450 460 552 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:59:39 2016 done: Thu Nov 3 17:59:39 2016 Total Scan time: 3.770 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]