Result of FASTA (omim) for
pF1KB5685
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5685, 402 aa
1>>>pF1KB5685 402 - 402 aa - 402 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7487+/-0.0005; mu= 14.1980+/- 0.031
mean_var=61.0926+/-12.838, 0's: 0 Z-trim(109.3): 148 B-trim: 994 in 2/46
Lambda= 0.164089
statistics sampled from 17294 (17442) to 17294 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.567), E-opt: 0.2 (0.205), width: 16
Scan time: 8.110
The best scores are: opt bits E(85289)
NP_000593 (OMIM: 173360,613329) plasminogen activa ( 402) 2644 634.8 1.1e-181
XP_016867749 (OMIM: 173360,613329) PREDICTED: plas ( 440) 2380 572.3 7.8e-163
NP_001130000 (OMIM: 177010) glia-derived nexin iso ( 397) 1012 248.5 2.2e-65
XP_016859821 (OMIM: 177010) PREDICTED: glia-derive ( 397) 1012 248.5 2.2e-65
XP_016859820 (OMIM: 177010) PREDICTED: glia-derive ( 397) 1012 248.5 2.2e-65
NP_001130002 (OMIM: 177010) glia-derived nexin iso ( 409) 1012 248.5 2.2e-65
XP_016859819 (OMIM: 177010) PREDICTED: glia-derive ( 398) 1001 245.9 1.3e-64
NP_006207 (OMIM: 177010) glia-derived nexin isofor ( 398) 1001 245.9 1.3e-64
XP_016859818 (OMIM: 177010) PREDICTED: glia-derive ( 398) 1001 245.9 1.3e-64
XP_005246698 (OMIM: 177010) PREDICTED: glia-derive ( 410) 1001 245.9 1.4e-64
XP_016862107 (OMIM: 602445,604218) PREDICTED: neur ( 410) 786 195.0 2.8e-49
NP_001116224 (OMIM: 602445,604218) neuroserpin pre ( 410) 786 195.0 2.8e-49
NP_005016 (OMIM: 602445,604218) neuroserpin precur ( 410) 786 195.0 2.8e-49
NP_006208 (OMIM: 605587) serpin I2 isoform 2 precu ( 405) 724 180.3 7.4e-45
NP_001012303 (OMIM: 605587) serpin I2 isoform 1 pr ( 415) 724 180.3 7.5e-45
XP_005245255 (OMIM: 107300,613118) PREDICTED: anti ( 416) 640 160.4 7.3e-39
NP_000479 (OMIM: 107300,613118) antithrombin-III p ( 464) 640 160.4 8.1e-39
NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 632 158.5 2.5e-38
NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 632 158.5 2.5e-38
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 615 154.5 4.2e-37
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 614 154.3 4.7e-37
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 614 154.3 4.7e-37
NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 614 154.3 4.7e-37
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 614 154.3 4.7e-37
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 614 154.3 4.7e-37
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 614 154.3 4.7e-37
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 614 154.3 4.7e-37
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 614 154.3 4.8e-37
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 614 154.3 4.8e-37
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 614 154.3 5e-37
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 614 154.3 5.7e-37
NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 612 153.8 6.6e-37
XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 612 153.8 6.6e-37
XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 612 153.8 6.6e-37
XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 594 149.5 1.4e-35
XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 594 149.5 1.4e-35
NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo ( 435) 594 149.5 1.4e-35
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 591 148.8 2.1e-35
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 591 148.8 2.1e-35
XP_011524440 (OMIM: 600518) PREDICTED: serpin B4 i ( 390) 582 146.7 9.4e-35
NP_002965 (OMIM: 600518) serpin B4 isoform 1 [Homo ( 390) 582 146.7 9.4e-35
NP_006206 (OMIM: 147935) kallistatin isoform 2 pre ( 427) 570 143.8 7.3e-34
NP_001275962 (OMIM: 147935) kallistatin isoform 2 ( 427) 570 143.8 7.3e-34
NP_001275961 (OMIM: 147935) kallistatin isoform 1 ( 464) 570 143.9 7.9e-34
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin ( 423) 569 143.6 8.5e-34
NP_000615 (OMIM: 601841) plasma serine protease in ( 406) 567 143.1 1.1e-33
XP_005267790 (OMIM: 605271) PREDICTED: protein Z-d ( 444) 567 143.1 1.2e-33
NP_057270 (OMIM: 605271) protein Z-dependent prote ( 444) 567 143.1 1.2e-33
NP_001094077 (OMIM: 605271) protein Z-dependent pr ( 444) 567 143.1 1.2e-33
XP_016876842 (OMIM: 605271) PREDICTED: protein Z-d ( 484) 567 143.1 1.3e-33
>>NP_000593 (OMIM: 173360,613329) plasminogen activator (402 aa)
initn: 2644 init1: 2644 opt: 2644 Z-score: 3382.8 bits: 634.8 E(85289): 1.1e-181
Smith-Waterman score: 2644; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS
310 320 330 340 350 360
370 380 390 400
pF1KB5 STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
::::::::::::::::::::::::::::::::::::::::::
NP_000 STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
370 380 390 400
>>XP_016867749 (OMIM: 173360,613329) PREDICTED: plasmino (440 aa)
initn: 2380 init1: 2380 opt: 2380 Z-score: 3044.4 bits: 572.3 E(85289): 7.8e-163
Smith-Waterman score: 2380; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS
310 320 330 340 350 360
370 380 390 400
pF1KB5 STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
::
XP_016 STGESGSGEAPRVSPPSPFRITGPQTRKGPRSPLGTEQLCLCSAITHSPPVSQPGKRAWD
370 380 390 400 410 420
>>NP_001130000 (OMIM: 177010) glia-derived nexin isoform (397 aa)
initn: 986 init1: 706 opt: 1012 Z-score: 1295.0 bits: 248.5 E(85289): 2.2e-65
Smith-Waterman score: 1012; 41.4% identity (73.9% similar) in 379 aa overlap (25-402:21-397)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
: : . .:.:. :..::.:.... :.:.::.
NP_001 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPH
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .....:.
NP_001 GIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::. .. :. . .:. :..:.: . : :: :::..:. ::.:::. .
NP_001 FVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLI
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 DQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTP
: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . : ..:
NP_001 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLP
. .:...::::::...::.:: : :. .::::. .:.. :. : . :. ..::
NP_001 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVAS
::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:.:: ::
NP_001 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS
300 310 320 330 340 350
360 370 380 390 400
pF1KB5 SSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
..:..:. :: .: .:.:::::: .::::::.::::::. .:
NP_001 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
360 370 380 390
>>XP_016859821 (OMIM: 177010) PREDICTED: glia-derived ne (397 aa)
initn: 986 init1: 706 opt: 1012 Z-score: 1295.0 bits: 248.5 E(85289): 2.2e-65
Smith-Waterman score: 1012; 41.4% identity (73.9% similar) in 379 aa overlap (25-402:21-397)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
: : . .:.:. :..::.:.... :.:.::.
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPH
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .....:.
XP_016 GIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::. .. :. . .:. :..:.: . : :: :::..:. ::.:::. .
XP_016 FVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLI
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 DQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTP
: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . : ..:
XP_016 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLP
. .:...::::::...::.:: : :. .::::. .:.. :. : . :. ..::
XP_016 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVAS
::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:.:: ::
XP_016 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS
300 310 320 330 340 350
360 370 380 390 400
pF1KB5 SSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
..:..:. :: .: .:.:::::: .::::::.::::::. .:
XP_016 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
360 370 380 390
>>XP_016859820 (OMIM: 177010) PREDICTED: glia-derived ne (397 aa)
initn: 986 init1: 706 opt: 1012 Z-score: 1295.0 bits: 248.5 E(85289): 2.2e-65
Smith-Waterman score: 1012; 41.4% identity (73.9% similar) in 379 aa overlap (25-402:21-397)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
: : . .:.:. :..::.:.... :.:.::.
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPH
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .....:.
XP_016 GIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::. .. :. . .:. :..:.: . : :: :::..:. ::.:::. .
XP_016 FVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLI
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 DQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTP
: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . : ..:
XP_016 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLP
. .:...::::::...::.:: : :. .::::. .:.. :. : . :. ..::
XP_016 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVAS
::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:.:: ::
XP_016 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS
300 310 320 330 340 350
360 370 380 390 400
pF1KB5 SSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
..:..:. :: .: .:.:::::: .::::::.::::::. .:
XP_016 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
360 370 380 390
>>NP_001130002 (OMIM: 177010) glia-derived nexin isoform (409 aa)
initn: 986 init1: 706 opt: 1012 Z-score: 1294.7 bits: 248.5 E(85289): 2.2e-65
Smith-Waterman score: 1012; 41.4% identity (73.9% similar) in 379 aa overlap (25-402:33-409)
10 20 30 40 50
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRN
: : . .:.:. :..::.:.... :
NP_001 DCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 VVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEI
.:.::.:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .
NP_001 IVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 STTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNL
....:.::. .. :. . .:. :..:.: . : :: :::..:. ::.::
NP_001 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 LGKGAVDQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNY
:. .: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . :
NP_001 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 TEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLP
..:. .:...::::::...::.:: : :. .::::. .:.. :. : . :.
NP_001 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 RLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNE
..::::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:
NP_001 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSE
310 320 330 340 350 360
360 370 380 390 400
pF1KB5 SGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
.:: ::..:..:. :: .: .:.:::::: .::::::.::::::. .:
NP_001 DGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
370 380 390 400
>>XP_016859819 (OMIM: 177010) PREDICTED: glia-derived ne (398 aa)
initn: 954 init1: 418 opt: 1001 Z-score: 1280.9 bits: 245.9 E(85289): 1.3e-64
Smith-Waterman score: 1001; 41.3% identity (73.7% similar) in 380 aa overlap (25-402:21-398)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
: : . .:.:. :..::.:.... :.:.::.
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPH
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .....:.
XP_016 GIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::. .. :. . .:. :..:.: . : :: :::..:. ::.:::. .
XP_016 FVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLI
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 DQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTP
: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . : ..:
XP_016 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLP
. .:...::::::...::.:: : :. .::::. .:.. :. : . :. ..::
XP_016 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD-QEPLHVAQALQKVKIEVNESGTVA
::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:.:: :
XP_016 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKA
300 310 320 330 340 350
360 370 380 390 400
pF1KB5 SSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
:..:..:. :: .: .:.:::::: .::::::.::::::. .:
XP_016 SAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
360 370 380 390
>>NP_006207 (OMIM: 177010) glia-derived nexin isoform a (398 aa)
initn: 954 init1: 418 opt: 1001 Z-score: 1280.9 bits: 245.9 E(85289): 1.3e-64
Smith-Waterman score: 1001; 41.3% identity (73.7% similar) in 380 aa overlap (25-402:21-398)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
: : . .:.:. :..::.:.... :.:.::.
NP_006 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPH
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .....:.
NP_006 GIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::. .. :. . .:. :..:.: . : :: :::..:. ::.:::. .
NP_006 FVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLI
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 DQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTP
: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . : ..:
NP_006 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLP
. .:...::::::...::.:: : :. .::::. .:.. :. : . :. ..::
NP_006 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD-QEPLHVAQALQKVKIEVNESGTVA
::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:.:: :
NP_006 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKA
300 310 320 330 340 350
360 370 380 390 400
pF1KB5 SSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
:..:..:. :: .: .:.:::::: .::::::.::::::. .:
NP_006 SAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
360 370 380 390
>>XP_016859818 (OMIM: 177010) PREDICTED: glia-derived ne (398 aa)
initn: 954 init1: 418 opt: 1001 Z-score: 1280.9 bits: 245.9 E(85289): 1.3e-64
Smith-Waterman score: 1001; 41.3% identity (73.7% similar) in 380 aa overlap (25-402:21-398)
10 20 30 40 50 60
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
: : . .:.:. :..::.:.... :.:.::.
XP_016 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPH
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .....:.
XP_016 GIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
::. .. :. . .:. :..:.: . : :: :::..:. ::.:::. .
XP_016 FVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLI
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 DQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTP
: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . : ..:
XP_016 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 DGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLP
. .:...::::::...::.:: : :. .::::. .:.. :. : . :. ..::
XP_016 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 KFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD-QEPLHVAQALQKVKIEVNESGTVA
::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.:.:: :
XP_016 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKA
300 310 320 330 340 350
360 370 380 390 400
pF1KB5 SSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
:..:..:. :: .: .:.:::::: .::::::.::::::. .:
XP_016 SAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
360 370 380 390
>>XP_005246698 (OMIM: 177010) PREDICTED: glia-derived ne (410 aa)
initn: 954 init1: 418 opt: 1001 Z-score: 1280.6 bits: 245.9 E(85289): 1.4e-64
Smith-Waterman score: 1001; 41.3% identity (73.7% similar) in 380 aa overlap (25-402:33-410)
10 20 30 40 50
pF1KB5 MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRN
: : . .:.:. :..::.:.... :
XP_005 DCRSSLVEGTMNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 VVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEI
.:.::.:.::::.:::: . :.:..:. .: . .. :.. :... : ... ::: .
XP_005 IVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN--GVGKILKKINKAIVSKKNKDIV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 STTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNL
....:.::. .. :. . .:. :..:.: . : :: :::..:. ::.::
XP_005 TVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 LGKGAVDQ-LTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNY
:. .: :::::::::.::.: ::. : .:..: : .::.. .:::.:: . :
XP_005 LSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 TEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLP
..:. .:...::::::...::.:: : :. .::::. .:.. :. : . :.
XP_005 GSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 RLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD-QEPLHVAQALQKVKIEVN
..::::. ...::..::. ::.:::: . .:.:.... .: :::.. :::.::::.
XP_005 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVS
310 320 330 340 350 360
360 370 380 390 400
pF1KB5 ESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
:.:: ::..:..:. :: .: .:.:::::: .::::::.::::::. .:
XP_005 EDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
370 380 390 400 410
402 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:04:00 2016 done: Fri Nov 4 04:04:01 2016
Total Scan time: 8.110 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]