FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5687, 244 aa
1>>>pF1KB5687 244 - 244 aa - 244 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9869+/-0.00102; mu= 16.3679+/- 0.062
mean_var=84.9046+/-17.683, 0's: 0 Z-trim(105.2): 165 B-trim: 260 in 1/52
Lambda= 0.139190
statistics sampled from 8115 (8308) to 8115 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.255), width: 16
Scan time: 1.930
The best scores are: opt bits E(32554)
CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 1615 334.2 4.9e-92
CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 1021 214.9 3.8e-56
CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 988 208.2 3.8e-54
CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 661 142.5 1.9e-34
CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 658 141.9 2.9e-34
CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 643 138.9 2.4e-33
CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 577 125.7 2.5e-29
CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 569 124.0 7e-29
CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 568 123.9 8.6e-29
CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 565 123.2 1.2e-28
CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 555 121.2 4.9e-28
CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 548 119.8 1.3e-27
CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 544 119.0 2.4e-27
CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 543 118.8 2.6e-27
CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 513 112.8 1.7e-25
CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 508 111.8 3.4e-25
CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 500 110.2 1.1e-24
CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 495 109.3 2.6e-24
CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 454 101.0 7.3e-22
CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 429 95.9 2e-20
CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 323 74.7 5.6e-14
>>CCDS2190.1 RND3 gene_id:390|Hs108|chr2 (244 aa)
initn: 1615 init1: 1615 opt: 1615 Z-score: 1765.8 bits: 334.2 E(32554): 4.9e-92
Smith-Waterman score: 1615; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
190 200 210 220 230 240
pF1KB5 CTVM
::::
CCDS21 CTVM
>>CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 (227 aa)
initn: 1015 init1: 975 opt: 1021 Z-score: 1121.6 bits: 214.9 E(32554): 3.8e-56
Smith-Waterman score: 1021; 64.0% identity (89.3% similar) in 225 aa overlap (20-244:4-227)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
:. .::::::::..:::::::.::::: .: .:::::::::
CCDS11 MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENY
10 20 30 40
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
::::::: .::::..:::::: ::::::::.::::::::::::::::::::::::::.::
CCDS11 TASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
::::::.:..::::: :.:::..:: :::..: ::...::. .:::.::..:.:::.
CCDS11 TQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSR
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
.:: ::::.:::::.: ... .....:. :.:. .: ... .::. . ...::.:::
CCDS11 SSERSVRDVFHVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPD-RGNEGEIHKDRAKS
170 180 190 200 210 220
pF1KB5 CTVM
:..:
CCDS11 CNLM
>>CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 (232 aa)
initn: 970 init1: 936 opt: 988 Z-score: 1085.6 bits: 208.2 E(32554): 3.8e-54
Smith-Waterman score: 1001; 58.2% identity (83.2% similar) in 244 aa overlap (1-244:1-232)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
:::::: : . .. ::.:.::: ::::::.:.:.::::.::.:::::::::
CCDS87 MKERRAPQPVVAR----------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENY
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
:: .: . ::.::::::::::::::::::: : ::::::.:::::::::.::.::::. :
CCDS87 TACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
: ..::.:..::.:::.:::::.:::.:::...:.:.::.:: .:::.:: :.: ::.
CCDS87 ILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
::.:...::..:.. :.:: . ... . .::. :.::: :: ... ..:.::::
CCDS87 TSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSEL--ISSTFKKEKAKS
180 190 200 210 220
pF1KB5 CTVM
:..:
CCDS87 CSIM
230
>>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa)
initn: 627 init1: 627 opt: 661 Z-score: 731.8 bits: 142.5 E(32554): 1.9e-34
Smith-Waterman score: 661; 52.0% identity (84.0% similar) in 175 aa overlap (22-196:4-177)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
.. :.:.:::. :::: :: ::.:: ::: :::::::::
CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY
10 20 30 40
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
.:..:.: ...::.::::.:. :: .:::::::.:..:.::.:. :..:... .:: :
CCDS27 VADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
...::::. ..::: :.:::.: : ::.. .: ::. ..: .::..::: :.::::
CCDS27 VKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSA-
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
.....::..:..:: :
CCDS27 KTKDGVREVFEMATRAALQARRGKKKSGCLVL
170 180 190
>>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa)
initn: 619 init1: 619 opt: 658 Z-score: 728.5 bits: 141.9 E(32554): 2.9e-34
Smith-Waterman score: 658; 48.7% identity (80.6% similar) in 191 aa overlap (22-212:4-188)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
.. :.:.:::. :::: :: ::.:: ::: :::::::::
CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY
10 20 30 40
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
:..:.: ...::.::::.:. :: .:::::::.:..:.::.:. :..:... .:: :
CCDS85 IADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
...::::. ..::: :.::: : : ::.. .: :: ..: .::..:.: :.::::
CCDS85 VKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSA-
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
.....::..:..:: ... .:..:: .:
CCDS85 KTKEGVREVFEMAT-----RAGLQVRKNKRRRGCPIL
170 180 190
pF1KB5 CTVM
>>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa)
initn: 619 init1: 596 opt: 643 Z-score: 712.1 bits: 138.9 E(32554): 2.4e-33
Smith-Waterman score: 643; 50.3% identity (81.6% similar) in 179 aa overlap (22-200:4-181)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
.. :.:::::. :::: :: ::.:: ::: :::::::::
CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENY
10 20 30 40
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
.:..:.: ...::.::::.:. :: .:::::::.:..:.::... :..:... .:: :
CCDS16 VADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
...::::. ..::. :.:::.: . .::. .: :: :.: :: .: : :.::::
CCDS16 VKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSA-
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
.....::..:..:: : ..:
CCDS16 KTKEGVREVFETATRAALQKRYGSQNGCINCCKVL
170 180 190
>>CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 (210 aa)
initn: 553 init1: 553 opt: 577 Z-score: 640.1 bits: 125.7 E(32554): 2.5e-29
Smith-Waterman score: 577; 41.2% identity (76.5% similar) in 187 aa overlap (25-211:19-204)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
:.:.:::. ::::.:: ::: :::.:.::::: :
CCDS81 MTAAQAAGEEAPPGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERY
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
..... . ..: .:::.:. :: .::: :::....:.:::.. :...:.....: :
CCDS81 MVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
...:: .. ...::::.::: : : . .: . ::.: .: .::...::..:.::::
CCDS81 VNHFCKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSAR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
.: :. .:. :. . ... ..: : .:
CCDS81 LHDN-VHAVFQEAAEVALSSRGRNFWRRITQGFCVVT
180 190 200 210
pF1KB5 CTVM
>>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa)
initn: 549 init1: 549 opt: 569 Z-score: 631.9 bits: 124.0 E(32554): 7e-29
Smith-Waterman score: 569; 44.2% identity (72.6% similar) in 190 aa overlap (20-207:2-188)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
: .:: :::::. ::: :: .. . :: .:.::::.::
CCDS53 MQAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY
10 20 30 40
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
.:. .: . ..:.::::.:. :: .::::::..:. ::::.. : ....: :: :
CCDS53 SANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
... :::: ..::: : ::: : .:. .:.... ::..: :: :::.:::. :.:::::
CCDS53 VRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL
110 120 130 140 150 160
190 200 210 220 230
pF1KB5 QSENSVRDIFHVATLA--CVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKA
.. ... .: : : : ..: ..
CCDS53 -TQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
170 180 190
>>CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 (211 aa)
initn: 558 init1: 540 opt: 568 Z-score: 630.3 bits: 123.9 E(32554): 8.6e-29
Smith-Waterman score: 568; 45.2% identity (72.9% similar) in 188 aa overlap (25-212:21-206)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
:::.:::. ::::.:: :... :::.:.:.:::.:
CCDS92 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKY
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
::: . .... :.:.::.:. :: .::::: .. ::::.:. : . :.:: :: :
CCDS92 TASVTVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
. .:: . :.:.:::.::: : : .: . :..: :: . .:: :: :.::::
CCDS92 VTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
:: :.:.:. :. . .. .: ..:.:..:
CCDS92 FREN-VEDVFREAAKVALSALKK-AQRQKKRRLCLLL
180 190 200 210
pF1KB5 CTVM
>>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa)
initn: 537 init1: 514 opt: 565 Z-score: 627.6 bits: 123.2 E(32554): 1.2e-28
Smith-Waterman score: 565; 44.0% identity (77.0% similar) in 191 aa overlap (20-210:2-187)
10 20 30 40 50 60
pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
:..:: :::::. ::: :: .. . ::..:.::::.::
CCDS77 MQSIKC--VVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNY
10 20 30 40
70 80 90 100 110 120
pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
.:. .: . ..:.::::.:. :: .: ::::.... .:::.:. : . ..: .::. :
CCDS77 SAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
. . ::.. .:::: :.:::.. .:: .:... :.:.. .:: .:::: :. :.:::::
CCDS77 VCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSAL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
: ...:...: :. : .: : .::..:
CCDS77 Q-QDGVKEVFAEAVRAVLNPTP--IKRGRSCILL
170 180 190
244 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:12:52 2016 done: Sat Nov 5 13:12:52 2016
Total Scan time: 1.930 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]