FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5687, 244 aa 1>>>pF1KB5687 244 - 244 aa - 244 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9869+/-0.00102; mu= 16.3679+/- 0.062 mean_var=84.9046+/-17.683, 0's: 0 Z-trim(105.2): 165 B-trim: 260 in 1/52 Lambda= 0.139190 statistics sampled from 8115 (8308) to 8115 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.255), width: 16 Scan time: 1.930 The best scores are: opt bits E(32554) CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 1615 334.2 4.9e-92 CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 1021 214.9 3.8e-56 CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 988 208.2 3.8e-54 CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 661 142.5 1.9e-34 CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 658 141.9 2.9e-34 CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 643 138.9 2.4e-33 CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 577 125.7 2.5e-29 CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 569 124.0 7e-29 CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 568 123.9 8.6e-29 CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 565 123.2 1.2e-28 CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 555 121.2 4.9e-28 CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 548 119.8 1.3e-27 CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 544 119.0 2.4e-27 CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 543 118.8 2.6e-27 CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 513 112.8 1.7e-25 CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 508 111.8 3.4e-25 CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 500 110.2 1.1e-24 CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 495 109.3 2.6e-24 CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 454 101.0 7.3e-22 CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 429 95.9 2e-20 CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 323 74.7 5.6e-14 >>CCDS2190.1 RND3 gene_id:390|Hs108|chr2 (244 aa) initn: 1615 init1: 1615 opt: 1615 Z-score: 1765.8 bits: 334.2 E(32554): 4.9e-92 Smith-Waterman score: 1615; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS 190 200 210 220 230 240 pF1KB5 CTVM :::: CCDS21 CTVM >>CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 (227 aa) initn: 1015 init1: 975 opt: 1021 Z-score: 1121.6 bits: 214.9 E(32554): 3.8e-56 Smith-Waterman score: 1021; 64.0% identity (89.3% similar) in 225 aa overlap (20-244:4-227) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY :. .::::::::..:::::::.::::: .: .::::::::: CCDS11 MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENY 10 20 30 40 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE ::::::: .::::..:::::: ::::::::.::::::::::::::::::::::::::.:: CCDS11 TASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL ::::::.:..::::: :.:::..:: :::..: ::...::. .:::.::..:.:::. CCDS11 TQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSR 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS .:: ::::.:::::.: ... .....:. :.:. .: ... .::. . ...::.::: CCDS11 SSERSVRDVFHVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPD-RGNEGEIHKDRAKS 170 180 190 200 210 220 pF1KB5 CTVM :..: CCDS11 CNLM >>CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 (232 aa) initn: 970 init1: 936 opt: 988 Z-score: 1085.6 bits: 208.2 E(32554): 3.8e-54 Smith-Waterman score: 1001; 58.2% identity (83.2% similar) in 244 aa overlap (1-244:1-232) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY :::::: : . .. ::.:.::: ::::::.:.:.::::.::.::::::::: CCDS87 MKERRAPQPVVAR----------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENY 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE :: .: . ::.::::::::::::::::::: : ::::::.:::::::::.::.::::. : CCDS87 TACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL : ..::.:..::.:::.:::::.:::.:::...:.:.::.:: .:::.:: :.: ::. CCDS87 ILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS ::.:...::..:.. :.:: . ... . .::. :.::: :: ... ..:.:::: CCDS87 TSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSEL--ISSTFKKEKAKS 180 190 200 210 220 pF1KB5 CTVM :..: CCDS87 CSIM 230 >>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa) initn: 627 init1: 627 opt: 661 Z-score: 731.8 bits: 142.5 E(32554): 1.9e-34 Smith-Waterman score: 661; 52.0% identity (84.0% similar) in 175 aa overlap (22-196:4-177) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY .. :.:.:::. :::: :: ::.:: ::: ::::::::: CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY 10 20 30 40 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE .:..:.: ...::.::::.:. :: .:::::::.:..:.::.:. :..:... .:: : CCDS27 VADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL ...::::. ..::: :.:::.: : ::.. .: ::. ..: .::..::: :.:::: CCDS27 VKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSA- 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS .....::..:..:: : CCDS27 KTKDGVREVFEMATRAALQARRGKKKSGCLVL 170 180 190 >>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa) initn: 619 init1: 619 opt: 658 Z-score: 728.5 bits: 141.9 E(32554): 2.9e-34 Smith-Waterman score: 658; 48.7% identity (80.6% similar) in 191 aa overlap (22-212:4-188) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY .. :.:.:::. :::: :: ::.:: ::: ::::::::: CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY 10 20 30 40 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE :..:.: ...::.::::.:. :: .:::::::.:..:.::.:. :..:... .:: : CCDS85 IADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL ...::::. ..::: :.::: : : ::.. .: :: ..: .::..:.: :.:::: CCDS85 VKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSA- 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS .....::..:..:: ... .:..:: .: CCDS85 KTKEGVREVFEMAT-----RAGLQVRKNKRRRGCPIL 170 180 190 pF1KB5 CTVM >>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa) initn: 619 init1: 596 opt: 643 Z-score: 712.1 bits: 138.9 E(32554): 2.4e-33 Smith-Waterman score: 643; 50.3% identity (81.6% similar) in 179 aa overlap (22-200:4-181) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY .. :.:::::. :::: :: ::.:: ::: ::::::::: CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENY 10 20 30 40 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE .:..:.: ...::.::::.:. :: .:::::::.:..:.::... :..:... .:: : CCDS16 VADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL ...::::. ..::. :.:::.: . .::. .: :: :.: :: .: : :.:::: CCDS16 VKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSA- 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS .....::..:..:: : ..: CCDS16 KTKEGVREVFETATRAALQKRYGSQNGCINCCKVL 170 180 190 >>CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 (210 aa) initn: 553 init1: 553 opt: 577 Z-score: 640.1 bits: 125.7 E(32554): 2.5e-29 Smith-Waterman score: 577; 41.2% identity (76.5% similar) in 187 aa overlap (25-211:19-204) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY :.:.:::. ::::.:: ::: :::.:.::::: : CCDS81 MTAAQAAGEEAPPGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERY 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE ..... . ..: .:::.:. :: .::: :::....:.:::.. :...:.....: : CCDS81 MVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL ...:: .. ...::::.::: : : . .: . ::.: .: .::...::..:.:::: CCDS81 VNHFCKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSAR 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS .: :. .:. :. . ... ..: : .: CCDS81 LHDN-VHAVFQEAAEVALSSRGRNFWRRITQGFCVVT 180 190 200 210 pF1KB5 CTVM >>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa) initn: 549 init1: 549 opt: 569 Z-score: 631.9 bits: 124.0 E(32554): 7e-29 Smith-Waterman score: 569; 44.2% identity (72.6% similar) in 190 aa overlap (20-207:2-188) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY : .:: :::::. ::: :: .. . :: .:.::::.:: CCDS53 MQAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY 10 20 30 40 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE .:. .: . ..:.::::.:. :: .::::::..:. ::::.. : ....: :: : CCDS53 SANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL ... :::: ..::: : ::: : .:. .:.... ::..: :: :::.:::. :.::::: CCDS53 VRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL 110 120 130 140 150 160 190 200 210 220 230 pF1KB5 QSENSVRDIFHVATLA--CVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKA .. ... .: : : : ..: .. CCDS53 -TQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 170 180 190 >>CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 (211 aa) initn: 558 init1: 540 opt: 568 Z-score: 630.3 bits: 123.9 E(32554): 8.6e-29 Smith-Waterman score: 568; 45.2% identity (72.9% similar) in 188 aa overlap (25-212:21-206) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY :::.:::. ::::.:: :... :::.:.:.:::.: CCDS92 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKY 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE ::: . .... :.:.::.:. :: .::::: .. ::::.:. : . :.:: :: : CCDS92 TASVTVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL . .:: . :.:.:::.::: : : .: . :..: :: . .:: :: :.:::: CCDS92 VTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS :: :.:.:. :. . .. .: ..:.:..: CCDS92 FREN-VEDVFREAAKVALSALKK-AQRQKKRRLCLLL 180 190 200 210 pF1KB5 CTVM >>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa) initn: 537 init1: 514 opt: 565 Z-score: 627.6 bits: 123.2 E(32554): 1.2e-28 Smith-Waterman score: 565; 44.0% identity (77.0% similar) in 191 aa overlap (20-210:2-187) 10 20 30 40 50 60 pF1KB5 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY :..:: :::::. ::: :: .. . ::..:.::::.:: CCDS77 MQSIKC--VVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNY 10 20 30 40 70 80 90 100 110 120 pF1KB5 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE .:. .: . ..:.::::.:. :: .: ::::.... .:::.:. : . ..: .::. : CCDS77 SAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL . . ::.. .:::: :.:::.. .:: .:... :.:.. .:: .:::: :. :.::::: CCDS77 VCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSAL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS : ...:...: :. : .: : .::..: CCDS77 Q-QDGVKEVFAEAVRAVLNPTP--IKRGRSCILL 170 180 190 244 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:12:52 2016 done: Sat Nov 5 13:12:52 2016 Total Scan time: 1.930 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]