FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5696, 245 aa
1>>>pF1KB5696 245 - 245 aa - 245 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9643+/-0.000994; mu= 11.7661+/- 0.060
mean_var=79.1119+/-15.389, 0's: 0 Z-trim(104.6): 16 B-trim: 9 in 1/49
Lambda= 0.144196
statistics sampled from 7992 (8003) to 7992 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.246), width: 16
Scan time: 2.220
The best scores are: opt bits E(32554)
CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1557 333.4 8.7e-92
CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1368 294.0 6e-80
CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1289 277.6 5.3e-75
CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1157 250.1 9.8e-67
CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1153 249.3 1.7e-66
CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1100 238.3 3.7e-63
CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 1060 230.0 1.2e-60
>>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa)
initn: 1557 init1: 1557 opt: 1557 Z-score: 1761.3 bits: 333.4 E(32554): 8.7e-92
Smith-Waterman score: 1557; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG
190 200 210 220 230 240
pF1KB5 EGGEN
:::::
CCDS62 EGGEN
>>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa)
initn: 1367 init1: 1367 opt: 1368 Z-score: 1548.8 bits: 294.0 E(32554): 6e-80
Smith-Waterman score: 1368; 87.3% identity (96.3% similar) in 245 aa overlap (1-245:3-246)
10 20 30 40 50
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSS
:::.:::::::::::::::::::: ::.::::: ::::::::::::::::::::::::
CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 WRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFY
:::.:::::::: ::::::..:::::::.::.::::::: ::.:.:::::.: ::::::
CCDS13 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
:::::::.:::.:::.::.:. :..::::::::::::::::::::::::::::::::::
CCDS13 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE
::::::::::::::::::::::::::::.:::::::::::::::::::::::..::::..
CCDS13 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
190 200 210 220 230 240
240
pF1KB5 AGEGGEN
:::: ::
CCDS13 AGEG-EN
>>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa)
initn: 1289 init1: 1289 opt: 1289 Z-score: 1460.0 bits: 277.6 E(32554): 5.3e-75
Smith-Waterman score: 1289; 79.6% identity (94.3% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR
:.:.::.::::::::::::::::.:::.:::::::::::::::::::::::::.:::.::
CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK
:.:::::::. ..:: :. ..::::.:.:::.::. :: ::.:.:: ::.. ::::::::
CCDS16 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
:::::.::::::: :::.: .:.:: ::::::.::::::::::::::::::::::::::
CCDS16 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG
:::.:: ::.::::::::::::::::.:.::::::::::::::::::::::. :.: .:.
CCDS16 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA
190 200 210 220 230 240
pF1KB5 EGGEN
::.::
CCDS16 EGAEN
>>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa)
initn: 1019 init1: 668 opt: 1157 Z-score: 1311.6 bits: 250.1 E(32554): 9.8e-67
Smith-Waterman score: 1157; 75.5% identity (89.4% similar) in 245 aa overlap (2-242:3-245)
10 20 30 40 50
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW
:...:.:.:.::::::::::::. ::.::: . ::::.:::::::::::::::::::
CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 RVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESK
::.::::::: .: ::: . .. :::::: ::. .::::::::.:::: : . : :::
CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 VFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFS
::::::::::::::::::.:. :...:. :. ::.:::::::..::::::::::::::::
CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 VFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGD
:::::: :.::.:: ::: :::.::::::::.:.:::::::::::::::::::::: : :
CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQ-D
190 200 210 220 230
240
pF1KB5 EAEAGEGGEN
: :::::
CCDS13 E-EAGEGN
240
>>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa)
initn: 998 init1: 653 opt: 1153 Z-score: 1307.1 bits: 249.3 E(32554): 1.7e-66
Smith-Waterman score: 1153; 74.8% identity (89.4% similar) in 246 aa overlap (1-242:2-245)
10 20 30 40 50
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW
.:...:::::.::::::::::::: ::.::: . ::::::::::::::::::::::::
CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 RVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESK
::.::::::: .: ::: .:.: :::::: ::. .:.::::::...:: : : : :::
CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 VFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFS
::::::::::::::::::.:. . .:..:..::.:: ::::..::::::::::::::.:
CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 VFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGD
:::::: :.::.:: :::::::.::::::::.:.:::::::::::::::::::::: : :
CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD
190 200 210 220 230 240
240
pF1KB5 EAEAGEGGEN
. .:::
CCDS55 D--GGEGNN
>>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa)
initn: 1098 init1: 789 opt: 1100 Z-score: 1247.5 bits: 238.3 E(32554): 3.7e-63
Smith-Waterman score: 1100; 71.1% identity (89.8% similar) in 246 aa overlap (1-244:1-241)
10 20 30 40 50 60
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR
:.. :.::::::::::::.:::: ::...:.: ::: :::::::::::::::..:..::
CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 VVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFY
:.::::::. ::.:.: .::::::.::::. .:. ::.::.. :: .:..:::.:::
CCDS28 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
:::::::::::::::.::::: :.:....:::::..:::::: ::.:::::::::::::.
CCDS28 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE
::: ::::.: :::::.::::.:.: ::::.::::::::::::::::::::.:. :.:
CCDS28 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEE--
190 200 210 220 230
240
pF1KB5 AGEGGEN
:::
CCDS28 ---GGEAPQEPQS
240
>>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa)
initn: 1040 init1: 743 opt: 1060 Z-score: 1202.3 bits: 230.0 E(32554): 1.2e-60
Smith-Waterman score: 1060; 69.0% identity (86.2% similar) in 239 aa overlap (2-238:3-241)
10 20 30 40 50
pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW
:...:: .:::::::::::.:. ::.:. . .::. :::::::::::::.::::.::
CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 RVVSSIEQKTE--GAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVF
:..:::::: : :.: : .: ::::. .::::. :: :.:..:.: ::: :. .:::::
CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 YLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVF
: ::::::.::::: :.:.:.: ...: ::. : .:. :. ::::::::::::::::
CCDS11 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 YYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEA
::::::::..:: :::.:::.::::::::::::::::::::::::::::::::: :::
CCDS11 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGE
190 200 210 220 230 240
240
pF1KB5 EAGEGGEN
:
CCDS11 EQNKEALQDVEDENQ
250
245 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:30:26 2016 done: Sat Nov 5 01:30:27 2016
Total Scan time: 2.220 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]