FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5696, 245 aa 1>>>pF1KB5696 245 - 245 aa - 245 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9643+/-0.000994; mu= 11.7661+/- 0.060 mean_var=79.1119+/-15.389, 0's: 0 Z-trim(104.6): 16 B-trim: 9 in 1/49 Lambda= 0.144196 statistics sampled from 7992 (8003) to 7992 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.246), width: 16 Scan time: 2.220 The best scores are: opt bits E(32554) CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1557 333.4 8.7e-92 CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1368 294.0 6e-80 CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1289 277.6 5.3e-75 CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1157 250.1 9.8e-67 CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1153 249.3 1.7e-66 CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1100 238.3 3.7e-63 CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 1060 230.0 1.2e-60 >>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa) initn: 1557 init1: 1557 opt: 1557 Z-score: 1761.3 bits: 333.4 E(32554): 8.7e-92 Smith-Waterman score: 1557; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 190 200 210 220 230 240 pF1KB5 EGGEN ::::: CCDS62 EGGEN >>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa) initn: 1367 init1: 1367 opt: 1368 Z-score: 1548.8 bits: 294.0 E(32554): 6e-80 Smith-Waterman score: 1368; 87.3% identity (96.3% similar) in 245 aa overlap (1-245:3-246) 10 20 30 40 50 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSS :::.:::::::::::::::::::: ::.::::: :::::::::::::::::::::::: CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 WRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFY :::.:::::::: ::::::..:::::::.::.::::::: ::.:.:::::.: :::::: CCDS13 WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY :::::::.:::.:::.::.:. :..:::::::::::::::::::::::::::::::::: CCDS13 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE ::::::::::::::::::::::::::::.:::::::::::::::::::::::..::::.. CCDS13 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 190 200 210 220 230 240 240 pF1KB5 AGEGGEN :::: :: CCDS13 AGEG-EN >>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa) initn: 1289 init1: 1289 opt: 1289 Z-score: 1460.0 bits: 277.6 E(32554): 5.3e-75 Smith-Waterman score: 1289; 79.6% identity (94.3% similar) in 245 aa overlap (1-245:1-245) 10 20 30 40 50 60 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR :.:.::.::::::::::::::::.:::.:::::::::::::::::::::::::.:::.:: CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK :.:::::::. ..:: :. ..::::.:.:::.::. :: ::.:.:: ::.. :::::::: CCDS16 VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE :::::.::::::: :::.: .:.:: ::::::.:::::::::::::::::::::::::: CCDS16 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG :::.:: ::.::::::::::::::::.:.::::::::::::::::::::::. :.: .:. CCDS16 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA 190 200 210 220 230 240 pF1KB5 EGGEN ::.:: CCDS16 EGAEN >>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa) initn: 1019 init1: 668 opt: 1157 Z-score: 1311.6 bits: 250.1 E(32554): 9.8e-67 Smith-Waterman score: 1157; 75.5% identity (89.4% similar) in 245 aa overlap (2-242:3-245) 10 20 30 40 50 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW :...:.:.:.::::::::::::. ::.::: . ::::.::::::::::::::::::: CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESK ::.::::::: .: ::: . .. :::::: ::. .::::::::.:::: : . : ::: CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 VFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFS ::::::::::::::::::.:. :...:. :. ::.:::::::..:::::::::::::::: CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 VFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGD :::::: :.::.:: ::: :::.::::::::.:.:::::::::::::::::::::: : : CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQ-D 190 200 210 220 230 240 pF1KB5 EAEAGEGGEN : ::::: CCDS13 E-EAGEGN 240 >>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa) initn: 998 init1: 653 opt: 1153 Z-score: 1307.1 bits: 249.3 E(32554): 1.7e-66 Smith-Waterman score: 1153; 74.8% identity (89.4% similar) in 246 aa overlap (1-242:2-245) 10 20 30 40 50 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW .:...:::::.::::::::::::: ::.::: . :::::::::::::::::::::::: CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESK ::.::::::: .: ::: .:.: :::::: ::. .:.::::::...:: : : : ::: CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 VFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFS ::::::::::::::::::.:. . .:..:..::.:: ::::..::::::::::::::.: CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 VFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGD :::::: :.::.:: :::::::.::::::::.:.:::::::::::::::::::::: : : CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD 190 200 210 220 230 240 240 pF1KB5 EAEAGEGGEN . .::: CCDS55 D--GGEGNN >>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa) initn: 1098 init1: 789 opt: 1100 Z-score: 1247.5 bits: 238.3 E(32554): 3.7e-63 Smith-Waterman score: 1100; 71.1% identity (89.8% similar) in 246 aa overlap (1-244:1-241) 10 20 30 40 50 60 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR :.. :.::::::::::::.:::: ::...:.: ::: :::::::::::::::..:..:: CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 VVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFY :.::::::. ::.:.: .::::::.::::. .:. ::.::.. :: .:..:::.::: CCDS28 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY :::::::::::::::.::::: :.:....:::::..:::::: ::.:::::::::::::. CCDS28 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE ::: ::::.: :::::.::::.:.: ::::.::::::::::::::::::::.:. :.: CCDS28 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEE-- 190 200 210 220 230 240 pF1KB5 AGEGGEN ::: CCDS28 ---GGEAPQEPQS 240 >>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa) initn: 1040 init1: 743 opt: 1060 Z-score: 1202.3 bits: 230.0 E(32554): 1.2e-60 Smith-Waterman score: 1060; 69.0% identity (86.2% similar) in 239 aa overlap (2-238:3-241) 10 20 30 40 50 pF1KB5 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW :...:: .:::::::::::.:. ::.:. . .::. :::::::::::::.::::.:: CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RVVSSIEQKTE--GAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVF :..:::::: : :.: : .: ::::. .::::. :: :.:..:.: ::: :. .::::: CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 YLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVF : ::::::.::::: :.:.:.: ...: ::. : .:. :. :::::::::::::::: CCDS11 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 YYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEA ::::::::..:: :::.:::.::::::::::::::::::::::::::::::::: ::: CCDS11 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGE 190 200 210 220 230 240 240 pF1KB5 EAGEGGEN : CCDS11 EQNKEALQDVEDENQ 250 245 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:30:26 2016 done: Sat Nov 5 01:30:27 2016 Total Scan time: 2.220 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]