FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5705, 744 aa 1>>>pF1KB5705 744 - 744 aa - 744 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4392+/-0.000446; mu= 11.2583+/- 0.028 mean_var=211.9656+/-44.702, 0's: 0 Z-trim(116.7): 208 B-trim: 140 in 1/54 Lambda= 0.088093 statistics sampled from 27895 (28164) to 27895 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.33), width: 16 Scan time: 13.300 The best scores are: opt bits E(85289) NP_150594 (OMIM: 605493) tripartite motif-containi ( 744) 4991 648.1 3.7e-185 XP_011518146 (OMIM: 605493) PREDICTED: tripartite ( 744) 4991 648.1 3.7e-185 NP_006449 (OMIM: 605493) tripartite motif-containi ( 744) 4991 648.1 3.7e-185 XP_016872587 (OMIM: 605493) PREDICTED: tripartite ( 744) 4991 648.1 3.7e-185 NP_001234935 (OMIM: 605493) tripartite motif-conta ( 744) 4991 648.1 3.7e-185 NP_001234936 (OMIM: 605493) tripartite motif-conta ( 625) 4122 537.6 5.8e-152 XP_011518147 (OMIM: 605493) PREDICTED: tripartite ( 625) 4122 537.6 5.8e-152 XP_016872588 (OMIM: 605493) PREDICTED: tripartite ( 625) 4122 537.6 5.8e-152 XP_016863437 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 XP_016863439 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 XP_016863440 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 NP_001123539 (OMIM: 614141,615490) tripartite moti ( 744) 3470 454.8 5.7e-127 XP_016863438 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 XP_016863441 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 XP_016863434 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 XP_016863433 (OMIM: 614141,615490) PREDICTED: trip ( 744) 3470 454.8 5.7e-127 XP_016863436 (OMIM: 614141,615490) PREDICTED: trip ( 761) 3470 454.8 5.8e-127 XP_016863435 (OMIM: 614141,615490) PREDICTED: trip ( 762) 3470 454.8 5.8e-127 XP_016863432 (OMIM: 614141,615490) PREDICTED: trip ( 770) 3470 454.9 5.8e-127 NP_056086 (OMIM: 614141,615490) tripartite motif-c ( 771) 3470 454.9 5.8e-127 XP_006714224 (OMIM: 614141,615490) PREDICTED: trip ( 748) 3452 452.5 2.8e-126 XP_006714225 (OMIM: 614141,615490) PREDICTED: trip ( 748) 3452 452.5 2.8e-126 XP_011530097 (OMIM: 614141,615490) PREDICTED: trip ( 748) 3452 452.5 2.8e-126 XP_006714223 (OMIM: 614141,615490) PREDICTED: trip ( 748) 3452 452.5 2.8e-126 XP_011530098 (OMIM: 614141,615490) PREDICTED: trip ( 748) 3452 452.5 2.8e-126 XP_011530100 (OMIM: 614141,615490) PREDICTED: trip ( 748) 3452 452.5 2.8e-126 XP_011530096 (OMIM: 614141,615490) PREDICTED: trip ( 765) 3452 452.6 2.8e-126 XP_006714222 (OMIM: 614141,615490) PREDICTED: trip ( 766) 3452 452.6 2.8e-126 XP_006714221 (OMIM: 614141,615490) PREDICTED: trip ( 774) 3452 452.6 2.9e-126 XP_006714220 (OMIM: 614141,615490) PREDICTED: trip ( 775) 3452 452.6 2.9e-126 XP_016863444 (OMIM: 614141,615490) PREDICTED: trip ( 619) 2894 381.5 5.5e-105 XP_016863443 (OMIM: 614141,615490) PREDICTED: trip ( 619) 2894 381.5 5.5e-105 XP_016863442 (OMIM: 614141,615490) PREDICTED: trip ( 623) 2876 379.3 2.7e-104 XP_006714228 (OMIM: 614141,615490) PREDICTED: trip ( 623) 2876 379.3 2.7e-104 NP_001289623 (OMIM: 614141,615490) tripartite moti ( 154) 579 86.6 8.2e-17 NP_001289622 (OMIM: 614141,615490) tripartite moti ( 162) 579 86.7 8.4e-17 NP_001289621 (OMIM: 614141,615490) tripartite moti ( 163) 579 86.7 8.5e-17 NP_079464 (OMIM: 609318) tripartite motif-containi ( 580) 514 79.0 6e-14 XP_011540501 (OMIM: 609318) PREDICTED: tripartite ( 476) 493 76.3 3.3e-13 NP_912730 (OMIM: 606474) tripartite motif-containi ( 358) 374 61.0 9.9e-09 NP_001139107 (OMIM: 609318) tripartite motif-conta ( 562) 365 60.1 2.9e-08 XP_011514891 (OMIM: 616996) PREDICTED: E3 ubiquiti ( 755) 329 55.6 8.5e-07 NP_112223 (OMIM: 616996) E3 ubiquitin-protein liga ( 755) 329 55.6 8.5e-07 NP_115935 (OMIM: 606474) tripartite motif-containi ( 400) 289 50.2 1.9e-05 NP_001007279 (OMIM: 605661) E3 ubiquitin-protein l ( 410) 288 50.1 2.1e-05 NP_434698 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 285 49.7 2.7e-05 NP_998755 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 285 49.7 2.7e-05 NP_005789 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 285 49.7 2.7e-05 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 263 47.1 0.00023 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 263 47.1 0.00024 >>NP_150594 (OMIM: 605493) tripartite motif-containing p (744 aa) initn: 4991 init1: 4991 opt: 4991 Z-score: 3445.2 bits: 648.1 E(85289): 3.7e-185 Smith-Waterman score: 4991; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA 670 680 690 700 710 720 730 740 pF1KB5 LTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::: NP_150 LTSDGHVVVADAGNHCFKAYRYLQ 730 740 >>XP_011518146 (OMIM: 605493) PREDICTED: tripartite moti (744 aa) initn: 4991 init1: 4991 opt: 4991 Z-score: 3445.2 bits: 648.1 E(85289): 3.7e-185 Smith-Waterman score: 4991; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA 670 680 690 700 710 720 730 740 pF1KB5 LTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::: XP_011 LTSDGHVVVADAGNHCFKAYRYLQ 730 740 >>NP_006449 (OMIM: 605493) tripartite motif-containing p (744 aa) initn: 4991 init1: 4991 opt: 4991 Z-score: 3445.2 bits: 648.1 E(85289): 3.7e-185 Smith-Waterman score: 4991; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA 670 680 690 700 710 720 730 740 pF1KB5 LTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::: NP_006 LTSDGHVVVADAGNHCFKAYRYLQ 730 740 >>XP_016872587 (OMIM: 605493) PREDICTED: tripartite moti (744 aa) initn: 4991 init1: 4991 opt: 4991 Z-score: 3445.2 bits: 648.1 E(85289): 3.7e-185 Smith-Waterman score: 4991; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA 670 680 690 700 710 720 730 740 pF1KB5 LTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::: XP_016 LTSDGHVVVADAGNHCFKAYRYLQ 730 740 >>NP_001234935 (OMIM: 605493) tripartite motif-containin (744 aa) initn: 4991 init1: 4991 opt: 4991 Z-score: 3445.2 bits: 648.1 E(85289): 3.7e-185 Smith-Waterman score: 4991; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLA 670 680 690 700 710 720 730 740 pF1KB5 LTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::: NP_001 LTSDGHVVVADAGNHCFKAYRYLQ 730 740 >>NP_001234936 (OMIM: 605493) tripartite motif-containin (625 aa) initn: 4122 init1: 4122 opt: 4122 Z-score: 2849.2 bits: 537.6 E(85289): 5.8e-152 Smith-Waterman score: 4122; 100.0% identity (100.0% similar) in 624 aa overlap (121-744:2-625) 100 110 120 130 140 150 pF1KB5 QAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVL :::::::::::::::::::::::::::::: NP_001 MKTMEFYCEACETAMCGECRAGEHREHGTVL 10 20 30 160 170 180 190 200 210 pF1KB5 LRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQ 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB5 ALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLV 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB5 RKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGE 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB5 GLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVY 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB5 TARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAV 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB5 RRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCI 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB5 QVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKI 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB5 GAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAV 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB5 NNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGN 520 530 540 550 560 570 700 710 720 730 740 pF1KB5 SRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ 580 590 600 610 620 >>XP_011518147 (OMIM: 605493) PREDICTED: tripartite moti (625 aa) initn: 4122 init1: 4122 opt: 4122 Z-score: 2849.2 bits: 537.6 E(85289): 5.8e-152 Smith-Waterman score: 4122; 100.0% identity (100.0% similar) in 624 aa overlap (121-744:2-625) 100 110 120 130 140 150 pF1KB5 QAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVL :::::::::::::::::::::::::::::: XP_011 MKTMEFYCEACETAMCGECRAGEHREHGTVL 10 20 30 160 170 180 190 200 210 pF1KB5 LRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQ 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB5 ALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLV 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB5 RKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGE 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB5 GLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVY 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB5 TARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAV 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB5 RRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCI 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB5 QVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKI 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB5 GAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAV 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB5 NNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGN 520 530 540 550 560 570 700 710 720 730 740 pF1KB5 SRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ 580 590 600 610 620 >>XP_016872588 (OMIM: 605493) PREDICTED: tripartite moti (625 aa) initn: 4122 init1: 4122 opt: 4122 Z-score: 2849.2 bits: 537.6 E(85289): 5.8e-152 Smith-Waterman score: 4122; 100.0% identity (100.0% similar) in 624 aa overlap (121-744:2-625) 100 110 120 130 140 150 pF1KB5 QAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVL :::::::::::::::::::::::::::::: XP_016 MKTMEFYCEACETAMCGECRAGEHREHGTVL 10 20 30 160 170 180 190 200 210 pF1KB5 LRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQ 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB5 ALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLV 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB5 RKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGE 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB5 GLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVY 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB5 TARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAV 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB5 RRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCI 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB5 QVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKI 400 410 420 430 440 450 580 590 600 610 620 630 pF1KB5 GAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAV 460 470 480 490 500 510 640 650 660 670 680 690 pF1KB5 NNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGN 520 530 540 550 560 570 700 710 720 730 740 pF1KB5 SRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ 580 590 600 610 620 >>XP_016863437 (OMIM: 614141,615490) PREDICTED: triparti (744 aa) initn: 2184 init1: 1692 opt: 3470 Z-score: 2400.5 bits: 454.8 E(85289): 5.7e-127 Smith-Waterman score: 3470; 67.3% identity (88.5% similar) in 740 aa overlap (8-744:9-744) 10 20 30 40 50 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSC :.: :. .:::::.:::::.::. :::::::::::::::::::::.:::::: XP_016 MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 PVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDP---HPLSVVAGRPLSCP :::::::::::.::.::::::::..::...:..: :.. :. .:.::.::::: XP_016 PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTP-GSNAEESSILETVTAVAAGKPLSCP 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 NHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQL ::.:..:::::..:::::: :: ::: :: :: :.::::::::.:: ::.:: :::.. XP_016 NHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQS ..:. ... : .:: ..:: . .: ..:..:...:. ::..:. .::. : :.::::: XP_016 DSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 QLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL ::::: :::: : : .:. ::: :. :::::.:.: :.: :: : :: .:.:: :: XP_016 QLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVR ....:..::..:. :::..:::.:.: :::::::::::...::: :.:.:::::::.: . XP_016 DFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCK 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 TGSAELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRV ::.: : ::.. :::. ..:.::::::..::.. ::.. ::. :: : .:::::.. XP_016 TGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 RALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRV ...: .:. :. . ::::::::: ..::.::::.::.:::::: :::.:::::.:.::: XP_016 KVIRSADVSPTTEGVKRRVKSPG--SGHVKQKAVKRPASMYSTG-KRKENPIEDDLIFRV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 GSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRP :..::.::::::::::.:...:.:..:::::::.:.:::.:::: :::.::::::::::: XP_016 GTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 TGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKS ::::: .::::.:::::.:::::: .::::::::.:.:::::::.:::::::::::::. XP_016 TGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 CCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFL :::: ::::::.: :::.:: ::.::::::.:::..:::..::::::::::.. .:::. XP_016 CCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFM 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 FKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGP .::::.:::::::::::::::::::::::::::::::::::.::::::::::::.::::: XP_016 LKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGP 660 670 680 690 700 710 720 730 740 pF1KB5 QGLALTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::.::::::.::::: XP_016 QGLALTSDGHVVVADSGNHCFKVYRYLQ 720 730 740 >>XP_016863439 (OMIM: 614141,615490) PREDICTED: triparti (744 aa) initn: 2184 init1: 1692 opt: 3470 Z-score: 2400.5 bits: 454.8 E(85289): 5.7e-127 Smith-Waterman score: 3470; 67.3% identity (88.5% similar) in 740 aa overlap (8-744:9-744) 10 20 30 40 50 pF1KB5 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSC :.: :. .:::::.:::::.::. :::::::::::::::::::::.:::::: XP_016 MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 PVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDP---HPLSVVAGRPLSCP :::::::::::.::.::::::::..::...:..: :.. :. .:.::.::::: XP_016 PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTP-GSNAEESSILETVTAVAAGKPLSCP 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 NHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQL ::.:..:::::..:::::: :: ::: :: :: :.::::::::.:: ::.:: :::.. XP_016 NHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQS ..:. ... : .:: ..:: . .: ..:..:...:. ::..:. .::. : :.::::: XP_016 DSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 QLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL ::::: :::: : : .:. ::: :. :::::.:.: :.: :: : :: .:.:: :: XP_016 QLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVR ....:..::..:. :::..:::.:.: :::::::::::...::: :.:.:::::::.: . XP_016 DFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCK 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 TGSAELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRV ::.: : ::.. :::. ..:.::::::..::.. ::.. ::. :: : .:::::.. XP_016 TGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 RALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRV ...: .:. :. . ::::::::: ..::.::::.::.:::::: :::.:::::.:.::: XP_016 KVIRSADVSPTTEGVKRRVKSPG--SGHVKQKAVKRPASMYSTG-KRKENPIEDDLIFRV 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 GSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRP :..::.::::::::::.:...:.:..:::::::.:.:::.:::: :::.::::::::::: XP_016 GTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 TGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKS ::::: .::::.:::::.:::::: .::::::::.:.:::::::.:::::::::::::. XP_016 TGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 CCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFL :::: ::::::.: :::.:: ::.::::::.:::..:::..::::::::::.. .:::. XP_016 CCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFM 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 FKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGP .::::.:::::::::::::::::::::::::::::::::::.::::::::::::.::::: XP_016 LKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGP 660 670 680 690 700 710 720 730 740 pF1KB5 QGLALTSDGHVVVADAGNHCFKAYRYLQ :::::::::::::::.::::::.::::: XP_016 QGLALTSDGHVVVADSGNHCFKVYRYLQ 720 730 740 744 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:46:55 2016 done: Thu Nov 3 22:46:57 2016 Total Scan time: 13.300 Total Display time: 0.230 Function used was FASTA [36.3.4 Apr, 2011]