FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5706, 717 aa 1>>>pF1KB5706 717 - 717 aa - 717 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4208+/-0.000428; mu= 10.4102+/- 0.027 mean_var=137.5047+/-27.745, 0's: 0 Z-trim(115.0): 22 B-trim: 208 in 1/53 Lambda= 0.109374 statistics sampled from 25223 (25237) to 25223 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.296), width: 16 Scan time: 10.390 The best scores are: opt bits E(85289) NP_001317 (OMIM: 600367) cleavage stimulation fact ( 717) 4774 765.5 0 NP_001028677 (OMIM: 600367) cleavage stimulation f ( 103) 502 90.9 2.7e-18 NP_001028678 (OMIM: 600367) cleavage stimulation f ( 44) 278 55.3 6e-08 >>NP_001317 (OMIM: 600367) cleavage stimulation factor s (717 aa) initn: 4774 init1: 4774 opt: 4774 Z-score: 4080.2 bits: 765.5 E(85289): 0 Smith-Waterman score: 4774; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KB5 MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 INIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVPPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 NTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYVTAALMEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYVTAALMEY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 YCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SGEIWARFLAFESNIGDLASILKVEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGEIWARFLAFESNIGDLASILKVEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 LKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQPRHLAPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 GLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIIT 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 GGAPELAVEGNGPVESNAVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGAPELAVEGNGPVESNAVLTKAVKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR 670 680 690 700 710 >>NP_001028677 (OMIM: 600367) cleavage stimulation facto (103 aa) initn: 498 init1: 498 opt: 502 Z-score: 449.4 bits: 90.9 E(85289): 2.7e-18 Smith-Waterman score: 502; 86.8% identity (89.0% similar) in 91 aa overlap (1-91:1-88) 10 20 30 40 50 60 pF1KB5 MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKE :::::::::::::::. : :.: : NP_001 FPSSGRFWKLYIEAEVTILFY---FFLYQYCSIHCSDRKQVRNIAN 70 80 90 100 130 140 150 160 170 180 pF1KB5 KMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPM >>NP_001028678 (OMIM: 600367) cleavage stimulation facto (44 aa) initn: 278 init1: 278 opt: 278 Z-score: 263.7 bits: 55.3 E(85289): 6e-08 Smith-Waterman score: 278; 100.0% identity (100.0% similar) in 43 aa overlap (1-43:1-43) 10 20 30 40 50 60 pF1KB5 MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQ ::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSILIREAQV 10 20 30 40 70 80 90 100 110 120 pF1KB5 FPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKE 717 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:04:42 2016 done: Sat Nov 5 15:04:43 2016 Total Scan time: 10.390 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]