Result of FASTA (omim) for
pF1KB5708
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5708, 718 aa
1>>>pF1KB5708 718 - 718 aa - 718 aa
Library: /omim/omim.rfq.tfa
61718354 residues in 86699 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4323+/-0.00044; mu= 1.4082+/- 0.027
mean_var=263.0134+/-55.372, 0's: 0 Z-trim(119.4): 255 B-trim: 1110 in 1/53
Lambda= 0.079083
statistics sampled from 33460 (33734) to 33460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.389), width: 16
Scan time: 13.740
The best scores are: opt bits E(86699)
NP_113607 (OMIM: 608004) NF-kappa-B inhibitor zeta ( 718) 4825 564.4 5.5e-160
NP_001005474 (OMIM: 608004) NF-kappa-B inhibitor z ( 618) 4143 486.6 1.3e-136
NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein ( 454) 301 48.1 9.3e-05
XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymp ( 539) 301 48.2 0.00011
XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymp ( 356) 290 46.8 0.00019
XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymp ( 434) 290 46.8 0.00022
XP_016865986 (OMIM: 610583) PREDICTED: ankyrin rep ( 689) 290 47.0 0.0003
XP_016865984 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 290 47.0 0.00031
XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymp ( 696) 290 47.0 0.00031
XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymp ( 378) 284 46.1 0.00031
XP_011533901 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 281 46.0 0.00062
XP_016865993 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 279 45.7 0.0007
XP_016865994 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 270 44.7 0.0014
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 277 45.9 0.0017
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 277 45.9 0.0017
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 277 45.9 0.0018
XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846) 277 45.9 0.0018
XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858) 277 45.9 0.0018
XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879) 277 45.9 0.0018
XP_016863601 (OMIM: 106410,600919) PREDICTED: anky (1689) 275 45.6 0.0019
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755) 275 45.6 0.002
XP_016863599 (OMIM: 106410,600919) PREDICTED: anky (1763) 275 45.6 0.002
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 275 45.6 0.002
XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772) 275 45.6 0.002
XP_016863594 (OMIM: 106410,600919) PREDICTED: anky (1810) 275 45.6 0.002
XP_016863592 (OMIM: 106410,600919) PREDICTED: anky (1816) 275 45.6 0.0021
XP_016863593 (OMIM: 106410,600919) PREDICTED: anky (1818) 275 45.6 0.0021
XP_016863590 (OMIM: 106410,600919) PREDICTED: anky (1839) 275 45.7 0.0021
XP_016863588 (OMIM: 106410,600919) PREDICTED: anky (1850) 275 45.7 0.0021
XP_016863587 (OMIM: 106410,600919) PREDICTED: anky (1851) 275 45.7 0.0021
XP_016863585 (OMIM: 106410,600919) PREDICTED: anky (1862) 275 45.7 0.0021
NP_001120965 (OMIM: 106410,600919) ankyrin-2 isofo (1863) 275 45.7 0.0021
XP_016863583 (OMIM: 106410,600919) PREDICTED: anky (1871) 275 45.7 0.0021
XP_016863584 (OMIM: 106410,600919) PREDICTED: anky (1871) 275 45.7 0.0021
NP_066187 (OMIM: 106410,600919) ankyrin-2 isoform (1872) 275 45.7 0.0021
XP_016863582 (OMIM: 106410,600919) PREDICTED: anky (1881) 275 45.7 0.0021
XP_016863581 (OMIM: 106410,600919) PREDICTED: anky (1882) 275 45.7 0.0021
XP_016863579 (OMIM: 106410,600919) PREDICTED: anky (1886) 275 45.7 0.0021
XP_016863578 (OMIM: 106410,600919) PREDICTED: anky (1887) 275 45.7 0.0021
XP_016863577 (OMIM: 106410,600919) PREDICTED: anky (1893) 275 45.7 0.0021
XP_016863576 (OMIM: 106410,600919) PREDICTED: anky (1898) 275 45.7 0.0021
XP_016863575 (OMIM: 106410,600919) PREDICTED: anky (1899) 275 45.7 0.0021
XP_016863574 (OMIM: 106410,600919) PREDICTED: anky (1902) 275 45.7 0.0021
XP_016863573 (OMIM: 106410,600919) PREDICTED: anky (1915) 275 45.7 0.0021
XP_016863572 (OMIM: 106410,600919) PREDICTED: anky (1917) 275 45.7 0.0021
XP_016863571 (OMIM: 106410,600919) PREDICTED: anky (1926) 275 45.7 0.0021
XP_016863570 (OMIM: 106410,600919) PREDICTED: anky (1931) 275 45.7 0.0021
XP_016863569 (OMIM: 106410,600919) PREDICTED: anky (1970) 275 45.7 0.0022
XP_016863568 (OMIM: 106410,600919) PREDICTED: anky (2006) 275 45.7 0.0022
XP_016863567 (OMIM: 106410,600919) PREDICTED: anky (2020) 275 45.7 0.0022
>>NP_113607 (OMIM: 608004) NF-kappa-B inhibitor zeta iso (718 aa)
initn: 4825 init1: 4825 opt: 4825 Z-score: 2993.4 bits: 564.4 E(86699): 5.5e-160
Smith-Waterman score: 4825; 100.0% identity (100.0% similar) in 718 aa overlap (1-718:1-718)
10 20 30 40 50 60
pF1KB5 MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 GSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 KELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 ALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 NPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 HYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 HYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 SSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 QVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 QSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 QSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 QFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 MGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQ
610 620 630 640 650 660
670 680 690 700 710
pF1KB5 YRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 YRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
670 680 690 700 710
>>NP_001005474 (OMIM: 608004) NF-kappa-B inhibitor zeta (618 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 2573.7 bits: 486.6 E(86699): 1.3e-136
Smith-Waterman score: 4143; 100.0% identity (100.0% similar) in 618 aa overlap (101-718:1-618)
80 90 100 110 120 130
pF1KB5 SSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSH
::::::::::::::::::::::::::::::
NP_001 MGVGRQQRGPFQGVRVKNSVKELLLHIRSH
10 20 30
140 150 160 170 180 190
pF1KB5 KQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 PQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSP
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 AEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEY
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 SPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAH
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 LHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLA
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 NISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 NQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNY
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 DGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDR
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR
520 530 540 550 560 570
680 690 700 710
pF1KB5 LLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
580 590 600 610
>>NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein [Ho (454 aa)
initn: 176 init1: 88 opt: 301 Z-score: 206.5 bits: 48.1 E(86699): 9.3e-05
Smith-Waterman score: 376; 31.7% identity (57.1% similar) in 312 aa overlap (400-710:93-362)
370 380 390 400 410 420
pF1KB5 HLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKL
: ::.:. ..: :. . .:.
NP_005 GCDLPAVPGPPHGLARPEALYYPGALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLS
70 80 90 100 110 120
430 440 450 460 470 480
pF1KB5 ANISQDQFLSKDADGDTFLHIAVAQGRR-ALSYVLARKMNALHMLDIKEHNGQSAFQVAV
:.:.. : :::: :::::.:: :. .. ... . ::: .. :. ...::
NP_005 ADIAMA--TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAV
130 140 150 160 170 180
490 500 510 520 530 540
pF1KB5 AANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEAT
.. .:. ::. ::. . : :.: :. :. :.:. .:. .. .::::
NP_005 ITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGT--LDLEAR
190 200 210 220 230
550 560 570 580 590 600
pF1KB5 NYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAK
:::::: :: :: . : :: :.. :.. :: ..:
NP_005 NYDGLTALHVAV-----------------NTECQE----------TVQLLLERGADIDAV
240 250 260 270
610 620 630 640 650 660
pF1KB5 DRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDA
: ::::. : :.:. .: ...:.:. . :::. :.:..::: :.. :
NP_005 DIKSGRSPLIHAVENNSLSMVQLLLQHGAN---VNAQMYSGSSALHSASGRGL----LPL
280 290 300 310 320
670 680 690 700 710
pF1KB5 VRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
:: :.:.::: : .: .:. :. .. . ... ::.::.
NP_005 VRTLVRSGADSSLKNCHNDTPLMVARS----RRVIDILRGKATRPASTSQPDPSPDRSAN
330 340 350 360 370 380
NP_005 TSPESSSRLSSNGLLSASPSSSPSQSPPRDPPGFPMAPPNFFLPSPSPPAFLPFAGVLRG
390 400 410 420 430 440
>>XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymphoma (539 aa)
initn: 176 init1: 88 opt: 301 Z-score: 205.5 bits: 48.2 E(86699): 0.00011
Smith-Waterman score: 376; 31.7% identity (57.1% similar) in 312 aa overlap (400-710:178-447)
370 380 390 400 410 420
pF1KB5 HLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKL
: ::.:. ..: :. . .:.
XP_011 GCDLPAVPGPPHGLARPEALYYPGALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLS
150 160 170 180 190 200
430 440 450 460 470 480
pF1KB5 ANISQDQFLSKDADGDTFLHIAVAQGRR-ALSYVLARKMNALHMLDIKEHNGQSAFQVAV
:.:.. : :::: :::::.:: :. .. ... . ::: .. :. ...::
XP_011 ADIAMA--TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAV
210 220 230 240 250 260
490 500 510 520 530 540
pF1KB5 AANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEAT
.. .:. ::. ::. . : :.: :. :. :.:. .:. .. .::::
XP_011 ITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGT--LDLEAR
270 280 290 300 310 320
550 560 570 580 590 600
pF1KB5 NYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAK
:::::: :: :: . : :: :.. :.. :: ..:
XP_011 NYDGLTALHVAV-----------------NTECQE----------TVQLLLERGADIDAV
330 340 350
610 620 630 640 650 660
pF1KB5 DRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDA
: ::::. : :.:. .: ...:.:. . :::. :.:..::: :.. :
XP_011 DIKSGRSPLIHAVENNSLSMVQLLLQHGAN---VNAQMYSGSSALHSASGRGL----LPL
360 370 380 390 400
670 680 690 700 710
pF1KB5 VRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
:: :.:.::: : .: .:. :. .. . ... ::.::.
XP_011 VRTLVRSGADSSLKNCHNDTPLMVARS----RRVIDILRGKATRPASTSQPDPSPDRSAN
410 420 430 440 450 460
XP_011 TSPESSSRLSSNGLLSASPSSSPSQSPPRDPPGFPMAPPNFFLPSPSPPAFLPFAGVLRG
470 480 490 500 510 520
>>XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymphoma (356 aa)
initn: 233 init1: 88 opt: 290 Z-score: 201.1 bits: 46.8 E(86699): 0.00019
Smith-Waterman score: 370; 32.5% identity (56.8% similar) in 292 aa overlap (400-690:53-306)
370 380 390 400 410 420
pF1KB5 HLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKL
: ::.:. ..: :. . .:.
XP_016 RLFTPTKEETAQRGEVFGQGHPARALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLS
30 40 50 60 70 80
430 440 450 460 470 480
pF1KB5 ANISQDQFLSKDADGDTFLHIAVAQGRR-ALSYVLARKMNALHMLDIKEHNGQSAFQVAV
:.:.. : :::: :::::.:: :. .. ... . ::: .. :. ...::
XP_016 ADIAMA--TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAV
90 100 110 120 130 140
490 500 510 520 530 540
pF1KB5 AANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEAT
.. .:. ::. ::. . : :.: :. :. :.:. .:. .. .::::
XP_016 ITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGT--LDLEAR
150 160 170 180 190
550 560 570 580 590 600
pF1KB5 NYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAK
:::::: :: :: . : :: :.. :.. :: ..:
XP_016 NYDGLTALHVAV-----------------NTECQE----------TVQLLLERGADIDAV
200 210 220 230
610 620 630 640 650 660
pF1KB5 DRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDA
: ::::. : :.:. .: ...:.:. . :::. :.:..::: :.. :
XP_016 DIKSGRSPLIHAVENNSLSMVQLLLQHGAN---VNAQMYSGSSALHSASGRGL----LPL
240 250 260 270 280
670 680 690 700 710
pF1KB5 VRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
:: :.:.::: : .: .:. :.
XP_016 VRTLVRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPCTRVSAGWLQASVPERRGVRV
290 300 310 320 330 340
>>XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymphoma (434 aa)
initn: 151 init1: 88 opt: 290 Z-score: 200.0 bits: 46.8 E(86699): 0.00022
Smith-Waterman score: 370; 32.5% identity (56.8% similar) in 292 aa overlap (400-690:53-306)
370 380 390 400 410 420
pF1KB5 HLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKL
: ::.:. ..: :. . .:.
XP_016 RLFTPTKEETAQRGEVFGQGHPARALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLS
30 40 50 60 70 80
430 440 450 460 470 480
pF1KB5 ANISQDQFLSKDADGDTFLHIAVAQGRR-ALSYVLARKMNALHMLDIKEHNGQSAFQVAV
:.:.. : :::: :::::.:: :. .. ... . ::: .. :. ...::
XP_016 ADIAMA--TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAV
90 100 110 120 130 140
490 500 510 520 530 540
pF1KB5 AANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEAT
.. .:. ::. ::. . : :.: :. :. :.:. .:. .. .::::
XP_016 ITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGT--LDLEAR
150 160 170 180 190
550 560 570 580 590 600
pF1KB5 NYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAK
:::::: :: :: . : :: :.. :.. :: ..:
XP_016 NYDGLTALHVAV-----------------NTECQE----------TVQLLLERGADIDAV
200 210 220 230
610 620 630 640 650 660
pF1KB5 DRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDA
: ::::. : :.:. .: ...:.:. . :::. :.:..::: :.. :
XP_016 DIKSGRSPLIHAVENNSLSMVQLLLQHGAN---VNAQMYSGSSALHSASGRGL----LPL
240 250 260 270 280
670 680 690 700 710
pF1KB5 VRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
:: :.:.::: : .: .:. :.
XP_016 VRTLVRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPCTRVSAGWLQVIDILRGKATR
290 300 310 320 330 340
>>XP_016865986 (OMIM: 610583) PREDICTED: ankyrin repeat (689 aa)
initn: 174 init1: 98 opt: 290 Z-score: 197.3 bits: 47.0 E(86699): 0.0003
Smith-Waterman score: 290; 32.1% identity (60.6% similar) in 246 aa overlap (486-714:16-244)
460 470 480 490 500 510
pF1KB5 RRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRT
::. .: : .:.: ::.: .: :::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKH-GRT
10 20 30 40
520 530 540 550 560
pF1KB5 PLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHN-----AVVHE-
:::. :.::: :.: . :.. ::.. . : :: :... : :..::
XP_016 PLHLAANKGHLPVVQILLKAG------CDLDVQDDGDQTALHRATVVGNTEIIAALIHEG
50 60 70 80 90
570 580 590 600 610 620
pF1KB5 --LQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLE
:.:... . ..: .. : .. : ::. :: : ::. :.: :::::: .... .
XP_016 CALDRQDKDGNTALHEASWHGFS--QSAKLLIKAGANVLAKN-KAGNTALHLACQNSHSQ
100 110 120 130 140 150
630 640 650 660 670 680
pF1KB5 LIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENE
:..: : . : .. : :.:::::::.:... ....:.. ::: . : ..
XP_016 STRVLL-LAG--SRADLKNNAGDTALHVAAALNHK----KVAKILLEAGADTTIVNNAGQ
160 170 180 190 200
690 700 710
pF1KB5 QPV-----HLVPDGPV----GEQIRRILKGKSIQQRAPPY
:. : :. . . :. :. .:.:....
XP_016 TPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGS
210 220 230 240 250 260
XP_016 VSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGH
270 280 290 300 310 320
>>XP_016865984 (OMIM: 610583) PREDICTED: ankyrin repeat (694 aa)
initn: 174 init1: 98 opt: 290 Z-score: 197.3 bits: 47.0 E(86699): 0.00031
Smith-Waterman score: 290; 32.1% identity (60.6% similar) in 246 aa overlap (486-714:16-244)
460 470 480 490 500 510
pF1KB5 RRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRT
::. .: : .:.: ::.: .: :::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKH-GRT
10 20 30 40
520 530 540 550 560
pF1KB5 PLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHN-----AVVHE-
:::. :.::: :.: . :.. ::.. . : :: :... : :..::
XP_016 PLHLAANKGHLPVVQILLKAG------CDLDVQDDGDQTALHRATVVGNTEIIAALIHEG
50 60 70 80 90
570 580 590 600 610 620
pF1KB5 --LQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLE
:.:... . ..: .. : .. : ::. :: : ::. :.: :::::: .... .
XP_016 CALDRQDKDGNTALHEASWHGFS--QSAKLLIKAGANVLAKN-KAGNTALHLACQNSHSQ
100 110 120 130 140 150
630 640 650 660 670 680
pF1KB5 LIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENE
:..: : . : .. : :.:::::::.:... ....:.. ::: . : ..
XP_016 STRVLL-LAG--SRADLKNNAGDTALHVAAALNHK----KVAKILLEAGADTTIVNNAGQ
160 170 180 190 200
690 700 710
pF1KB5 QPV-----HLVPDGPV----GEQIRRILKGKSIQQRAPPY
:. : :. . . :. :. .:.:....
XP_016 TPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKGS
210 220 230 240 250 260
XP_016 VSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGH
270 280 290 300 310 320
>>XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymphoma (696 aa)
initn: 151 init1: 88 opt: 290 Z-score: 197.2 bits: 47.0 E(86699): 0.00031
Smith-Waterman score: 370; 32.5% identity (56.8% similar) in 292 aa overlap (400-690:315-568)
370 380 390 400 410 420
pF1KB5 HLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKL
: ::.:. ..: :. . .:.
XP_011 GCDLPAVPGPPHGLARPEALYYPGALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLS
290 300 310 320 330 340
430 440 450 460 470 480
pF1KB5 ANISQDQFLSKDADGDTFLHIAVAQGRR-ALSYVLARKMNALHMLDIKEHNGQSAFQVAV
:.:.. : :::: :::::.:: :. .. ... . ::: .. :. ...::
XP_011 ADIAMA--TRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAV
350 360 370 380 390 400
490 500 510 520 530 540
pF1KB5 AANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEAT
.. .:. ::. ::. . : :.: :. :. :.:. .:. .. .::::
XP_011 ITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGT--LDLEAR
410 420 430 440 450 460
550 560 570 580 590 600
pF1KB5 NYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAK
:::::: :: :: . : :: :.. :.. :: ..:
XP_011 NYDGLTALHVAV-----------------NTECQE----------TVQLLLERGADIDAV
470 480 490
610 620 630 640 650 660
pF1KB5 DRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDA
: ::::. : :.:. .: ...:.:. . :::. :.:..::: :.. :
XP_011 DIKSGRSPLIHAVENNSLSMVQLLLQHGAN---VNAQMYSGSSALHSASGRGL----LPL
500 510 520 530 540
670 680 690 700 710
pF1KB5 VRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
:: :.:.::: : .: .:. :.
XP_011 VRTLVRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPCTRVSAGWLQVIDILRGKATR
550 560 570 580 590 600
>>XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymphoma (378 aa)
initn: 151 init1: 88 opt: 284 Z-score: 197.1 bits: 46.1 E(86699): 0.00031
Smith-Waterman score: 364; 32.6% identity (57.3% similar) in 288 aa overlap (404-690:1-250)
380 390 400 410 420 430
pF1KB5 FSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLANIS
::.:. ..: :. . .:. :.:.
XP_011 MGSPFPLVNLPTPLYPMMCPMEHPLSADIA
10 20 30
440 450 460 470 480 490
pF1KB5 QDQFLSKDADGDTFLHIAVAQGRR-ALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQ
. : :::: :::::.:: :. .. ... . ::: .. :. ...:: ..
XP_011 MAT--RADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTL
40 50 60 70 80
500 510 520 530 540 550
pF1KB5 HLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDG
.:. ::. ::. . : :.: :. :. :.:. .:. .. .:::: ::::
XP_011 PSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGT--LDLEARNYDG
90 100 110 120 130 140
560 570 580 590 600 610
pF1KB5 LTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKS
:: :: :: . : :: :.. :.. :: ..: : ::
XP_011 LTALHVAV-----------------NTECQE----------TVQLLLERGADIDAVDIKS
150 160 170
620 630 640 650 660 670
pF1KB5 GRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLL
::. : :.:. .: ...:.:. . :::. :.:..::: :.. : :: :
XP_011 GRSPLIHAVENNSLSMVQLLLQHGAN---VNAQMYSGSSALHSASGRGL----LPLVRTL
180 190 200 210 220 230
680 690 700 710
pF1KB5 MRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
.:.::: : .: .:. :.
XP_011 VRSGADSSLKNCHNDTPLMVARSRRVSRGSCGHAPCTRVSAGWLQVIDILRGKATRPAST
240 250 260 270 280 290
718 residues in 1 query sequences
61718354 residues in 86699 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Apr 6 11:39:20 2017 done: Thu Apr 6 11:39:22 2017
Total Scan time: 13.740 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]