FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5710, 717 aa 1>>>pF1KB5710 717 - 717 aa - 717 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.2738+/-0.000592; mu= -18.2261+/- 0.036 mean_var=613.8010+/-129.043, 0's: 0 Z-trim(118.8): 222 B-trim: 0 in 0/56 Lambda= 0.051768 statistics sampled from 31854 (32077) to 31854 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.376), width: 16 Scan time: 13.230 The best scores are: opt bits E(85289) NP_001093646 (OMIM: 607824) protein Hook homolog 2 ( 717) 4668 364.7 7.2e-100 NP_037444 (OMIM: 607824) protein Hook homolog 2 is ( 719) 4654 363.6 1.5e-99 XP_005259931 (OMIM: 607824) PREDICTED: protein Hoo ( 716) 4651 363.4 1.7e-99 XP_005259930 (OMIM: 607824) PREDICTED: protein Hoo ( 718) 4637 362.4 3.6e-99 XP_016882210 (OMIM: 607824) PREDICTED: protein Hoo ( 644) 4154 326.3 2.4e-88 XP_011526247 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_005259934 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_011526246 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_016882209 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_011526248 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_005259933 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_011526245 (OMIM: 607824) PREDICTED: protein Hoo ( 646) 4140 325.2 5e-88 XP_011526249 (OMIM: 607824) PREDICTED: protein Hoo ( 584) 3734 294.8 6.3e-79 NP_115786 (OMIM: 607825) protein Hook homolog 3 [H ( 718) 2272 185.7 5.3e-46 NP_056972 (OMIM: 607820) protein Hook homolog 1 [H ( 728) 2119 174.3 1.5e-42 XP_011539864 (OMIM: 607820) PREDICTED: protein Hoo ( 686) 1967 162.9 3.7e-39 XP_011539865 (OMIM: 607820) PREDICTED: protein Hoo ( 559) 1690 142.2 5.5e-33 XP_006710739 (OMIM: 607820) PREDICTED: protein Hoo ( 560) 1690 142.2 5.5e-33 XP_016856913 (OMIM: 607820) PREDICTED: protein Hoo ( 451) 1285 111.8 6e-24 XP_005264483 (OMIM: 260565,609736) PREDICTED: gird (1311) 402 46.4 0.00089 NP_001241872 (OMIM: 260565,609736) girdin isoform (1796) 402 46.5 0.0011 XP_011531270 (OMIM: 260565,609736) PREDICTED: gird (1797) 402 46.5 0.0011 XP_016859970 (OMIM: 260565,609736) PREDICTED: gird (1797) 402 46.5 0.0011 NP_060554 (OMIM: 260565,609736) girdin isoform 2 [ (1843) 402 46.5 0.0011 XP_011531269 (OMIM: 260565,609736) PREDICTED: gird (1843) 402 46.5 0.0011 XP_005264478 (OMIM: 260565,609736) PREDICTED: gird (1844) 402 46.5 0.0011 NP_001129069 (OMIM: 260565,609736) girdin isoform (1870) 402 46.5 0.0011 XP_011531267 (OMIM: 260565,609736) PREDICTED: gird (1871) 402 46.5 0.0011 XP_011531268 (OMIM: 260565,609736) PREDICTED: gird (1871) 402 46.5 0.0011 XP_016859968 (OMIM: 260565,609736) PREDICTED: gird (1972) 402 46.5 0.0012 XP_016859967 (OMIM: 260565,609736) PREDICTED: gird (1999) 402 46.5 0.0012 XP_016859966 (OMIM: 260565,609736) PREDICTED: gird (2000) 402 46.5 0.0012 XP_016859965 (OMIM: 260565,609736) PREDICTED: gird (2026) 402 46.6 0.0012 XP_005264475 (OMIM: 260565,609736) PREDICTED: gird (2027) 402 46.6 0.0012 >>NP_001093646 (OMIM: 607824) protein Hook homolog 2 iso (717 aa) initn: 4668 init1: 4668 opt: 4668 Z-score: 1913.9 bits: 364.7 E(85289): 7.2e-100 Smith-Waterman score: 4668; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KB5 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDSILLKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDSILLKRK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 LEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 YVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKL 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 LISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH 670 680 690 700 710 >>NP_037444 (OMIM: 607824) protein Hook homolog 2 isofor (719 aa) initn: 4830 init1: 3474 opt: 4654 Z-score: 1908.2 bits: 363.6 E(85289): 1.5e-99 Smith-Waterman score: 4654; 99.7% identity (99.7% similar) in 719 aa overlap (1-717:1-719) 10 20 30 40 50 60 pF1KB5 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTED--SILLK ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_037 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDAISILLK 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 RKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 RKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERY 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB5 RRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 RRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB5 KLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 KLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH 670 680 690 700 710 >>XP_005259931 (OMIM: 607824) PREDICTED: protein Hook ho (716 aa) initn: 3893 init1: 3724 opt: 4651 Z-score: 1907.1 bits: 363.4 E(85289): 1.7e-99 Smith-Waterman score: 4651; 99.9% identity (99.9% similar) in 717 aa overlap (1-717:1-716) 10 20 30 40 50 60 pF1KB5 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDSILLKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDSILLKRK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 LEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERYRR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_005 LEEHLQKLHEADLELQRKREYIEELEPPTDSST-RRIEELQHNLQKKDADLRAMEERYRR 550 560 570 580 590 610 620 630 640 650 660 pF1KB5 YVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEEKL 600 610 620 630 640 650 670 680 690 700 710 pF1KB5 LISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH 660 670 680 690 700 710 >>XP_005259930 (OMIM: 607824) PREDICTED: protein Hook ho (718 aa) initn: 4475 init1: 3474 opt: 4637 Z-score: 1901.4 bits: 362.4 E(85289): 3.6e-99 Smith-Waterman score: 4637; 99.6% identity (99.6% similar) in 719 aa overlap (1-717:1-718) 10 20 30 40 50 60 pF1KB5 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWLQGISED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGKLLQLVLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQSRRYYFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTPGLTAKKLLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQEAADRE 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTED--SILLK ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_005 RQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDAISILLK 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 RKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEERY ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: XP_005 RKLEEHLQKLHEADLELQRKREYIEELEPPTDSST-RRIEELQHNLQKKDADLRAMEERY 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 RRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDFEKSRSQREQEE 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 KLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPLGRLASLNLRPTDKH 660 670 680 690 700 710 >>XP_016882210 (OMIM: 607824) PREDICTED: protein Hook ho (644 aa) initn: 4154 init1: 4154 opt: 4154 Z-score: 1707.0 bits: 326.3 E(85289): 2.4e-88 Smith-Waterman score: 4154; 100.0% identity (100.0% similar) in 644 aa overlap (74-717:1-644) 50 60 70 80 90 100 pF1KB5 IDPSWFNEAWLQGISEDPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIG :::::::::::::::::::::::::::::: XP_016 MVLRSLVEYSQDVLAHPVSEEHLPDVSLIG 10 20 30 110 120 130 140 150 160 pF1KB5 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB5 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB5 LQEQGGKTEDSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEQGGKTEDSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHN 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB5 LQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHL 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB5 EMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRGPL 580 590 600 610 620 630 710 pF1KB5 GRLASLNLRPTDKH :::::::::::::: XP_016 GRLASLNLRPTDKH 640 >>XP_011526247 (OMIM: 607824) PREDICTED: protein Hook ho (646 aa) initn: 4316 init1: 2960 opt: 4140 Z-score: 1701.4 bits: 325.2 E(85289): 5e-88 Smith-Waterman score: 4140; 99.7% identity (99.7% similar) in 646 aa overlap (74-717:1-646) 50 60 70 80 90 100 pF1KB5 IDPSWFNEAWLQGISEDPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIG :::::::::::::::::::::::::::::: XP_011 MVLRSLVEYSQDVLAHPVSEEHLPDVSLIG 10 20 30 110 120 130 140 150 160 pF1KB5 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB5 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB5 LQEQGGKTED--SILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB5 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB5 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG 580 590 600 610 620 630 710 pF1KB5 PLGRLASLNLRPTDKH :::::::::::::::: XP_011 PLGRLASLNLRPTDKH 640 >>XP_005259934 (OMIM: 607824) PREDICTED: protein Hook ho (646 aa) initn: 4316 init1: 2960 opt: 4140 Z-score: 1701.4 bits: 325.2 E(85289): 5e-88 Smith-Waterman score: 4140; 99.7% identity (99.7% similar) in 646 aa overlap (74-717:1-646) 50 60 70 80 90 100 pF1KB5 IDPSWFNEAWLQGISEDPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIG :::::::::::::::::::::::::::::: XP_005 MVLRSLVEYSQDVLAHPVSEEHLPDVSLIG 10 20 30 110 120 130 140 150 160 pF1KB5 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB5 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB5 LQEQGGKTED--SILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB5 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB5 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG 580 590 600 610 620 630 710 pF1KB5 PLGRLASLNLRPTDKH :::::::::::::::: XP_005 PLGRLASLNLRPTDKH 640 >>XP_011526246 (OMIM: 607824) PREDICTED: protein Hook ho (646 aa) initn: 4316 init1: 2960 opt: 4140 Z-score: 1701.4 bits: 325.2 E(85289): 5e-88 Smith-Waterman score: 4140; 99.7% identity (99.7% similar) in 646 aa overlap (74-717:1-646) 50 60 70 80 90 100 pF1KB5 IDPSWFNEAWLQGISEDPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIG :::::::::::::::::::::::::::::: XP_011 MVLRSLVEYSQDVLAHPVSEEHLPDVSLIG 10 20 30 110 120 130 140 150 160 pF1KB5 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB5 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB5 LQEQGGKTED--SILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB5 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB5 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG 580 590 600 610 620 630 710 pF1KB5 PLGRLASLNLRPTDKH :::::::::::::::: XP_011 PLGRLASLNLRPTDKH 640 >>XP_016882209 (OMIM: 607824) PREDICTED: protein Hook ho (646 aa) initn: 4316 init1: 2960 opt: 4140 Z-score: 1701.4 bits: 325.2 E(85289): 5e-88 Smith-Waterman score: 4140; 99.7% identity (99.7% similar) in 646 aa overlap (74-717:1-646) 50 60 70 80 90 100 pF1KB5 IDPSWFNEAWLQGISEDPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIG :::::::::::::::::::::::::::::: XP_016 MVLRSLVEYSQDVLAHPVSEEHLPDVSLIG 10 20 30 110 120 130 140 150 160 pF1KB5 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB5 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB5 LQEQGGKTED--SILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB5 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB5 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG 580 590 600 610 620 630 710 pF1KB5 PLGRLASLNLRPTDKH :::::::::::::::: XP_016 PLGRLASLNLRPTDKH 640 >>XP_011526248 (OMIM: 607824) PREDICTED: protein Hook ho (646 aa) initn: 4316 init1: 2960 opt: 4140 Z-score: 1701.4 bits: 325.2 E(85289): 5e-88 Smith-Waterman score: 4140; 99.7% identity (99.7% similar) in 646 aa overlap (74-717:1-646) 50 60 70 80 90 100 pF1KB5 IDPSWFNEAWLQGISEDPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIG :::::::::::::::::::::::::::::: XP_011 MVLRSLVEYSQDVLAHPVSEEHLPDVSLIG 10 20 30 110 120 130 140 150 160 pF1KB5 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFSDPAELGKLLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PETYGNFDSQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPEGEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQAL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVTKE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETLLR 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB5 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDLQKA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB5 LQEQGGKTED--SILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEQGGKTEDAISILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQ 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB5 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIR 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB5 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFLAQQRLATNSRRG 580 590 600 610 620 630 710 pF1KB5 PLGRLASLNLRPTDKH :::::::::::::::: XP_011 PLGRLASLNLRPTDKH 640 717 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:09:43 2016 done: Sat Nov 5 16:09:45 2016 Total Scan time: 13.230 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]