FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5714, 721 aa 1>>>pF1KB5714 721 - 721 aa - 721 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7199+/-0.000475; mu= 17.6176+/- 0.029 mean_var=67.1157+/-13.429, 0's: 0 Z-trim(107.7): 46 B-trim: 114 in 1/53 Lambda= 0.156553 statistics sampled from 15793 (15813) to 15793 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.521), E-opt: 0.2 (0.185), width: 16 Scan time: 11.230 The best scores are: opt bits E(85289) NP_114091 (OMIM: 606151,615981,616562) Bardet-Bied ( 721) 4711 1073.8 0 XP_005256137 (OMIM: 606151,615981,616562) PREDICTE ( 721) 4705 1072.4 0 >>NP_114091 (OMIM: 606151,615981,616562) Bardet-Biedl sy (721 aa) initn: 4711 init1: 4711 opt: 4711 Z-score: 5746.1 bits: 1073.8 E(85289): 0 Smith-Waterman score: 4711; 100.0% identity (100.0% similar) in 721 aa overlap (1-721:1-721) 10 20 30 40 50 60 pF1KB5 MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 PLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS 670 680 690 700 710 720 pF1KB5 S : NP_114 S >>XP_005256137 (OMIM: 606151,615981,616562) PREDICTED: B (721 aa) initn: 4705 init1: 4705 opt: 4705 Z-score: 5738.8 bits: 1072.4 E(85289): 0 Smith-Waterman score: 4705; 99.9% identity (100.0% similar) in 721 aa overlap (1-721:1-721) 10 20 30 40 50 60 pF1KB5 MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLESDVSLLSINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTAS 670 680 690 700 710 720 pF1KB5 S : XP_005 S 721 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:10:18 2016 done: Sat Nov 5 16:10:20 2016 Total Scan time: 11.230 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]