Result of FASTA (omim) for
pF1KB5737
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5737, 795 aa
1>>>pF1KB5737 795 - 795 aa - 795 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5285+/-0.000357; mu= 17.3119+/- 0.022
mean_var=133.1566+/-27.021, 0's: 0 Z-trim(118.4): 178 B-trim: 673 in 2/54
Lambda= 0.111146
statistics sampled from 31158 (31336) to 31158 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.367), width: 16
Scan time: 14.040
The best scores are: opt bits E(85289)
NP_003110 (OMIM: 602783,607259) paraplegin isoform ( 795) 5236 851.4 0
XP_006721327 (OMIM: 602783,607259) PREDICTED: para ( 809) 4764 775.7 0
XP_016879087 (OMIM: 602783,607259) PREDICTED: para ( 561) 3634 594.4 4.6e-169
XP_016879086 (OMIM: 602783,607259) PREDICTED: para ( 618) 3634 594.4 4.9e-169
XP_016879088 (OMIM: 602783,607259) PREDICTED: para ( 489) 2916 479.2 1.9e-134
NP_955399 (OMIM: 602783,607259) paraplegin isoform ( 489) 2916 479.2 1.9e-134
XP_005256378 (OMIM: 602783,607259) PREDICTED: para ( 463) 2908 477.9 4.4e-134
NP_006787 (OMIM: 604581,610246,614487) AFG3-like p ( 797) 1792 299.1 4.9e-80
XP_011523903 (OMIM: 604581,610246,614487) PREDICTE ( 730) 1302 220.5 2e-56
NP_001240795 (OMIM: 607472) ATP-dependent zinc met ( 683) 1015 174.5 1.4e-42
NP_055078 (OMIM: 607472) ATP-dependent zinc metall ( 716) 1015 174.5 1.4e-42
XP_011517602 (OMIM: 607472) PREDICTED: ATP-depende ( 740) 1015 174.5 1.5e-42
NP_647473 (OMIM: 607472) ATP-dependent zinc metall ( 773) 1015 174.5 1.5e-42
NP_009057 (OMIM: 167320,601023,613954,616687) tran ( 806) 641 114.6 1.8e-24
NP_001186092 (OMIM: 601681) 26S protease regulator ( 398) 634 113.2 2.3e-24
NP_002796 (OMIM: 601681) 26S protease regulatory s ( 406) 634 113.2 2.3e-24
XP_016876961 (OMIM: 602708) PREDICTED: 26S proteas ( 288) 627 111.9 4e-24
NP_002797 (OMIM: 602708) 26S protease regulatory s ( 403) 627 112.0 5.1e-24
NP_002794 (OMIM: 154365) 26S protease regulatory s ( 433) 622 111.3 9.3e-24
XP_016863318 (OMIM: 613940,616577) PREDICTED: sper ( 765) 620 111.2 1.8e-23
XP_016863317 (OMIM: 613940,616577) PREDICTED: sper ( 819) 620 111.2 1.9e-23
NP_001332785 (OMIM: 613940,616577) spermatogenesis ( 892) 620 111.2 2e-23
NP_660208 (OMIM: 613940,616577) spermatogenesis-as ( 893) 620 111.2 2e-23
XP_011529980 (OMIM: 613940,616577) PREDICTED: sper ( 916) 620 111.3 2e-23
XP_016863314 (OMIM: 613940,616577) PREDICTED: sper ( 917) 620 111.3 2e-23
XP_016876959 (OMIM: 602706) PREDICTED: 26S proteas ( 367) 598 107.4 1.2e-22
NP_001317141 (OMIM: 602706) 26S protease regulator ( 367) 598 107.4 1.2e-22
NP_002793 (OMIM: 602706) 26S protease regulatory s ( 440) 598 107.4 1.4e-22
NP_694546 (OMIM: 602707) 26S protease regulatory s ( 387) 584 105.1 5.9e-22
NP_006494 (OMIM: 602707) 26S protease regulatory s ( 418) 584 105.2 6.2e-22
XP_016856875 (OMIM: 602426) PREDICTED: nuclear val ( 738) 578 104.4 1.8e-21
NP_996671 (OMIM: 602426) nuclear valosin-containin ( 750) 578 104.4 1.8e-21
NP_001230076 (OMIM: 602426) nuclear valosin-contai ( 765) 578 104.4 1.9e-21
XP_016856872 (OMIM: 602426) PREDICTED: nuclear val ( 812) 578 104.5 2e-21
NP_002524 (OMIM: 602426) nuclear valosin-containin ( 856) 578 104.5 2e-21
XP_016856868 (OMIM: 602426) PREDICTED: nuclear val ( 890) 578 104.5 2.1e-21
NP_002795 (OMIM: 186852) 26S protease regulatory s ( 439) 571 103.1 2.7e-21
XP_016863315 (OMIM: 613940,616577) PREDICTED: sper ( 859) 573 103.7 3.6e-21
NP_001303242 (OMIM: 601498,614862,614863,616617) p ( 892) 543 98.9 1e-19
XP_011512963 (OMIM: 601498,614862,614863,616617) P ( 952) 543 98.9 1.1e-19
NP_000278 (OMIM: 601498,614862,614863,616617) pero ( 980) 543 98.9 1.1e-19
XP_016873515 (OMIM: 186852) PREDICTED: 26S proteas ( 461) 538 97.8 1.1e-19
NP_001230075 (OMIM: 602426) nuclear valosin-contai ( 667) 526 96.1 5.5e-19
XP_011542502 (OMIM: 602426) PREDICTED: nuclear val ( 765) 526 96.1 6.1e-19
XP_011542501 (OMIM: 602426) PREDICTED: nuclear val ( 765) 526 96.1 6.1e-19
XP_011542500 (OMIM: 602426) PREDICTED: nuclear val ( 777) 526 96.1 6.1e-19
XP_016856871 (OMIM: 602426) PREDICTED: nuclear val ( 839) 526 96.1 6.5e-19
XP_016856870 (OMIM: 602426) PREDICTED: nuclear val ( 839) 526 96.1 6.5e-19
XP_011542498 (OMIM: 602426) PREDICTED: nuclear val ( 883) 526 96.2 6.7e-19
XP_016856869 (OMIM: 602426) PREDICTED: nuclear val ( 889) 526 96.2 6.8e-19
>>NP_003110 (OMIM: 602783,607259) paraplegin isoform 1 p (795 aa)
initn: 5236 init1: 5236 opt: 5236 Z-score: 4542.5 bits: 851.4 E(85289): 0
Smith-Waterman score: 5236; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 NAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 MVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 NLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEE
730 740 750 760 770 780
790
pF1KB5 TQQPPLGGEEPTWPK
:::::::::::::::
NP_003 TQQPPLGGEEPTWPK
790
>>XP_006721327 (OMIM: 602783,607259) PREDICTED: parapleg (809 aa)
initn: 4939 init1: 4764 opt: 4764 Z-score: 4133.4 bits: 775.7 E(85289): 0
Smith-Waterman score: 4764; 99.9% identity (99.9% similar) in 729 aa overlap (1-729:1-729)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 NAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 MVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 NLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEE
::::::: :
XP_006 NLDKLQARALCVTWGSCLGPLDCRPQPAAAASGQVWAVPSPAEAGLPVDPCSSRLTKQLC
730 740 750 760 770 780
>>XP_016879087 (OMIM: 602783,607259) PREDICTED: parapleg (561 aa)
initn: 3634 init1: 3634 opt: 3634 Z-score: 3156.2 bits: 594.4 E(85289): 4.6e-169
Smith-Waterman score: 3634; 100.0% identity (100.0% similar) in 554 aa overlap (1-554:1-554)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
::::::::::::::
XP_016 HTLNFEYAVERVLAVWGLRRL
550 560
>>XP_016879086 (OMIM: 602783,607259) PREDICTED: parapleg (618 aa)
initn: 3634 init1: 3634 opt: 3634 Z-score: 3155.7 bits: 594.4 E(85289): 4.9e-169
Smith-Waterman score: 3634; 100.0% identity (100.0% similar) in 554 aa overlap (1-554:1-554)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
::::::::::::::
XP_016 HTLNFEYAVERVLAAWVWWAQPSPSLMGAELQPLTVGRRAAAARGCGGTAVLSAQQGLCG
550 560 570 580 590 600
>>XP_016879088 (OMIM: 602783,607259) PREDICTED: parapleg (489 aa)
initn: 2916 init1: 2916 opt: 2916 Z-score: 2534.8 bits: 479.2 E(85289): 1.9e-134
Smith-Waterman score: 2916; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
::::::::::::::::::::::
XP_016 MSGFSNTEEEQTLNQLLVEMDGASLDQLPSQGTMRKLRGKTPACSCLTEPTGSRRAMEGH
430 440 450 460 470 480
>>NP_955399 (OMIM: 602783,607259) paraplegin isoform 2 p (489 aa)
initn: 2916 init1: 2916 opt: 2916 Z-score: 2534.8 bits: 479.2 E(85289): 1.9e-134
Smith-Waterman score: 2916; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
::::::::::::::::::::::
NP_955 MSGFSNTEEEQTLNQLLVEMDGASLDQLPSQGTMRKLRGKTPACSCLTEPTGSRRAMEGH
430 440 450 460 470 480
>>XP_005256378 (OMIM: 602783,607259) PREDICTED: parapleg (463 aa)
initn: 2908 init1: 2908 opt: 2908 Z-score: 2528.2 bits: 477.9 E(85289): 4.4e-134
Smith-Waterman score: 2908; 100.0% identity (100.0% similar) in 441 aa overlap (1-441:1-441)
10 20 30 40 50 60
pF1KB5 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
:::::::::::::::::::::
XP_005 MSGFSNTEEEQTLNQLLVEMDVFYAEIEELKLVYPYHGVLHSD
430 440 450 460
>>NP_006787 (OMIM: 604581,610246,614487) AFG3-like prote (797 aa)
initn: 826 init1: 663 opt: 1792 Z-score: 1558.0 bits: 299.1 E(85289): 4.9e-80
Smith-Waterman score: 1792; 45.6% identity (74.5% similar) in 671 aa overlap (134-790:139-794)
110 120 130 140 150 160
pF1KB5 SRLKQKNKEKDKSKGKAPEEDEEERRRRERDDQMYRER-LRTLLVIAVVMSLLNALSTSG
::. .: : : : . :: : :. ::
NP_006 GGGGGGGGKRGGKKDDSHWWSRFQKGDIPWDDKDFRMFFLWTALFWGGVMFYL-LLKRSG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 GSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKF
:.:.:::...:.:: :.:..:: . :.: . :: . : . . ......: :
NP_006 REITWKDFVNNYLSKGVVDRLEVVNKR-FVRVTFTPGKT----PVDGQYVWFNIGSVDTF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 EEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRL--AGMTGR
:..:.. ..::.::...:.:: : . :. : :. :.. .:.: :..: ::. ::
NP_006 ERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRGPAGI-GR
230 240 250 260 270 280
290 300 310 320 330
pF1KB5 EG-GFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGA
: :.... .. . .. .. :.:::::: .:::::. :::..::.:... .:::
NP_006 TGRGMGGLFSVGETTAKVLKDEI--DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGA
290 300 310 320 330
340 350 360 370 380 390
pF1KB5 KVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARA
:.::::.: :::: ::::::::.: ::.:::....: ::.:.. :.: ::::.:: ::
NP_006 KIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARK
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB5 RAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRAD
::::..::::::::.::. : ...:.:.:::::::::::..:: .:..::.::: :
NP_006 NAPCILFIDEIDAVGRKRGRGNFG-GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPD
400 410 420 430 440 450
460 470 480 490 500 510
pF1KB5 ILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKL--TQSSTFYSQRLAELTPGFS
::: ::.::::.::..:: : .. : ::. ::. ::: : . ...:: ::::::
NP_006 ILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFS
460 470 480 490 500 510
520 530 540 550 560 570
pF1KB5 GADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESG
:::.::.:::::: :::. :.. .:: :.:::..: ::...:. ::.:.::.::.:
NP_006 GADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAG
520 530 540 550 560 570
580 590 600 610 620 630
pF1KB5 HALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEA
::..::.:::.. ..:::: :: . .::.::.::..:.:.:::::..::::.::::.::
NP_006 HAVAGWYLEHADPLLKVSIIPR-GKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEE
580 590 600 610 620 630
640 650 660 670 680 690
pF1KB5 LSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQ
. :...:.::::::::::. ::... :::: .: ::: ..: : . ..:.:.. .
NP_006 IFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDM-VLEKPYSEATAR
640 650 660 670 680 690
700 710 720 730 740 750
pF1KB5 MMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPK--
..: :.:.:. ::..: .: .. .. .: ::::::.. .:. :.:: : . :
NP_006 LIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKST
700 710 720 730 740 750
760 770 780 790
pF1KB5 --KMIAPQRWIDAQREK----QDLGEEETEETQQPPLGGEEPTWPK
... .: . .: ..:. .: ..:: ::.
NP_006 YEEFVEGTGSLDEDTSLPEGLKDWNKEREKEKEEPP--GEKVAN
760 770 780 790
>>XP_011523903 (OMIM: 604581,610246,614487) PREDICTED: A (730 aa)
initn: 1351 init1: 500 opt: 1302 Z-score: 1133.8 bits: 220.5 E(85289): 2e-56
Smith-Waterman score: 1364; 39.3% identity (65.3% similar) in 671 aa overlap (134-790:139-727)
110 120 130 140 150 160
pF1KB5 SRLKQKNKEKDKSKGKAPEEDEEERRRRERDDQMYRER-LRTLLVIAVVMSLLNALSTSG
::. .: : : : . :: : :. ::
XP_011 GGGGGGGGKRGGKKDDSHWWSRFQKGDIPWDDKDFRMFFLWTALFWGGVMFYL-LLKRSG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 GSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKF
:.:.:::...:.:: :.:..:: . :.: . :: . : . . ......: :
XP_011 REITWKDFVNNYLSKGVVDRLEVVNKR-FVRVTFTPGKT----PVDGQYVWFNIGSVDTF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 EEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRL--AGMTGR
:..:.. ..::.::...:.:: : . :. : :. :.. .:.: :..: ::. ::
XP_011 ERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRGPAGI-GR
230 240 250 260 270 280
290 300 310 320 330
pF1KB5 EG-GFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGA
: :.... .. . .. .. :.:::::: .:::::. :::..::.:... .:::
XP_011 TGRGMGGLFSVGETTAKVLKDEI--DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGA
290 300 310 320 330
340 350 360 370 380 390
pF1KB5 KVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARA
:.::::.: :::: ::::::::.: ::.:::....: ::.:.. :.: ::::.:: ::
XP_011 KIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARK
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB5 RAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRAD
::::..::::::::.::. : ...:.:.:::::::::::..:: .:..::.::: :
XP_011 NAPCILFIDEIDAVGRKRGRGNFG-GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPD
400 410 420 430 440 450
460 470 480 490 500 510
pF1KB5 ILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKL--TQSSTFYSQRLAELTPGFS
::: ::.::::.::..:: : .. : ::. ::. ::: : . ...:: ::::::
XP_011 ILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFS
460 470 480 490 500 510
520 530 540 550 560 570
pF1KB5 GADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESG
:::.::.:::::: :::. :.. .:: :.:::..: ::...:. ::.:.::.::.:
XP_011 GADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAG
520 530 540 550 560 570
580 590 600 610 620 630
pF1KB5 HALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEA
::..::.:::.. ..:.
XP_011 HAVAGWYLEHADPLLKIV------------------------------------------
580 590
640 650 660 670 680 690
pF1KB5 LSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQ
:::: .: ::: ..: : . ..:.:.. .
XP_011 --------------------------QFGMNEKVGQISFDLPRQGDM-VLEKPYSEATAR
600 610 620
700 710 720 730 740 750
pF1KB5 MMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPK--
..: :.:.:. ::..: .: .. .. .: ::::::.. .:. :.:: : . :
XP_011 LIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKST
630 640 650 660 670 680
760 770 780 790
pF1KB5 --KMIAPQRWIDAQREK----QDLGEEETEETQQPPLGGEEPTWPK
... .: . .: ..:. .: ..:: ::.
XP_011 YEEFVEGTGSLDEDTSLPEGLKDWNKEREKEKEEPP--GEKVAN
690 700 710 720 730
>>NP_001240795 (OMIM: 607472) ATP-dependent zinc metallo (683 aa)
initn: 913 init1: 470 opt: 1015 Z-score: 885.5 bits: 174.5 E(85289): 1.4e-42
Smith-Waterman score: 1076; 38.6% identity (73.5% similar) in 456 aa overlap (296-747:236-675)
270 280 290 300 310 320
pF1KB5 AILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFV
. :: . :.:.:. : :..::: :..: :
NP_001 ILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVV
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB5 DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGL
..::.:..: ::.:.::: ::.:::: ::::::.::: ::.::: .: :: :.. :.
NP_001 EFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGV
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB5 GAARVRSLFKEARARAPCIVYIDEIDAVGKKR-STTMSGFSNTEEEQTLNQLLVEMDGMG
::.:.:.::.::.: :::...:::.:.:: :: . : .: .::.::::.::::.
NP_001 GASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYS----RQTINQLLAEMDGFK
330 340 350 360 370 380
450 460 470 480 490 500
pF1KB5 TTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTF
.. ::....:: . ::.::.::::.: .: . : .. : ::.. .:...:. ::
NP_001 PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVD-
390 400 410 420 430 440
510 520 530 540 550 560
pF1KB5 YSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILS
. .:. : :::::.. :. :.:::.:: .:. : ..:.. ...: : ..: ..
NP_001 -PEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEID
450 460 470 480 490
570 580 590 600 610 620
pF1KB5 KEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPR-DQHLFTKEQLF
.... ..:.::::::..... . . . :..: :: . .:: ...::. :. :. ::.
NP_001 NKNKTITAYHESGHAIIAYYTKDAMPINKATIMPR-GPTLGHVSLLPENDRWNETRAQLL
500 510 520 530 540 550
630 640 650 660 670 680
pF1KB5 ERMCMALGGRASEALSF--NEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQE
.: ...:::..: : : ...:.::..:. ..:.:: :: .:::. .: ... ..
NP_001 AQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDT--
560 570 580 590 600 610
690 700 710 720 730 740
pF1KB5 GLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYE
:. .: :. ...: :.:. .:......:. . . . ::.::: :... .
NP_001 -----GK--LSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAK
620 630 640 650 660
750 760 770 780 790
pF1KB5 DIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEETQQPPLGGEEPTWPK
.:. ..
NP_001 EIQIVLEGKKLEVR
670 680
795 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:21:42 2016 done: Sat Nov 5 15:21:44 2016
Total Scan time: 14.040 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]