FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5738, 740 aa 1>>>pF1KB5738 740 - 740 aa - 740 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7154+/-0.000453; mu= 17.9150+/- 0.028 mean_var=84.9051+/-16.896, 0's: 0 Z-trim(110.5): 190 B-trim: 17 in 1/50 Lambda= 0.139190 statistics sampled from 18589 (18815) to 18589 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.221), width: 16 Scan time: 10.870 The best scores are: opt bits E(85289) NP_004930 (OMIM: 601257) ATP-dependent RNA helicas ( 740) 5029 1020.8 0 NP_001309271 (OMIM: 616533) probable ATP-dependent ( 674) 374 86.0 5.6e-16 XP_006717299 (OMIM: 616533) PREDICTED: probable AT ( 691) 374 86.0 5.7e-16 XP_011517224 (OMIM: 616533) PREDICTED: probable AT ( 691) 374 86.0 5.7e-16 NP_001309272 (OMIM: 616533) probable ATP-dependent ( 722) 374 86.0 5.9e-16 NP_001309270 (OMIM: 616533) probable ATP-dependent ( 755) 374 86.0 6.1e-16 XP_005272264 (OMIM: 616533) PREDICTED: probable AT ( 755) 374 86.0 6.1e-16 XP_011517223 (OMIM: 616533) PREDICTED: probable AT ( 787) 374 86.0 6.3e-16 NP_073616 (OMIM: 616533) probable ATP-dependent RN ( 851) 374 86.0 6.8e-16 NP_653333 (OMIM: 605800) heterogeneous nuclear rib ( 756) 349 81.0 2e-14 NP_001308140 (OMIM: 605800) heterogeneous nuclear ( 756) 349 81.0 2e-14 NP_001308137 (OMIM: 605800) heterogeneous nuclear ( 756) 349 81.0 2e-14 XP_011524697 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 349 81.0 2e-14 XP_005258520 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 349 81.0 2e-14 XP_011524696 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 349 81.0 2e-14 XP_011524695 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 349 81.0 2e-14 XP_005258521 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 349 81.0 2e-14 XP_005258522 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 349 81.0 2e-14 NP_001287945 (OMIM: 605800) heterogeneous nuclear ( 767) 349 81.0 2e-14 XP_005258518 (OMIM: 605800) PREDICTED: heterogeneo ( 777) 349 81.0 2e-14 XP_011524694 (OMIM: 605800) PREDICTED: heterogeneo ( 792) 349 81.0 2.1e-14 NP_008971 (OMIM: 605800) heterogeneous nuclear rib ( 856) 349 81.0 2.2e-14 XP_005258516 (OMIM: 605800) PREDICTED: heterogeneo ( 866) 349 81.0 2.2e-14 XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 306 72.3 6.2e-12 NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 306 72.3 6.3e-12 XP_005245576 (OMIM: 174300,615464) PREDICTED: prob ( 576) 306 72.3 6.4e-12 NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 306 72.3 6.8e-12 XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 306 72.3 6.8e-12 XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 306 72.3 6.8e-12 XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 306 72.3 6.8e-12 NP_004492 (OMIM: 602869) heterogeneous nuclear rib ( 806) 280 67.1 3.1e-10 XP_016856606 (OMIM: 602869) PREDICTED: heterogeneo ( 806) 280 67.1 3.1e-10 XP_016856604 (OMIM: 602869) PREDICTED: heterogeneo ( 825) 280 67.2 3.2e-10 NP_114032 (OMIM: 602869) heterogeneous nuclear rib ( 825) 280 67.2 3.2e-10 XP_016856605 (OMIM: 602869) PREDICTED: heterogeneo ( 825) 280 67.2 3.2e-10 XP_016862507 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314) 282 67.7 3.5e-10 NP_071347 (OMIM: 614472) E3 ubiquitin-protein liga (1314) 282 67.7 3.5e-10 XP_011532297 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314) 282 67.7 3.5e-10 XP_006713348 (OMIM: 614472) PREDICTED: E3 ubiquiti (1314) 282 67.7 3.5e-10 XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 274 65.8 4.4e-10 XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 274 65.8 5.1e-10 XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 274 65.8 5.1e-10 XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 274 65.9 5.7e-10 NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 274 65.9 6e-10 XP_016884803 (OMIM: 300160,300958) PREDICTED: ATP- ( 475) 270 65.0 8.2e-10 XP_016884802 (OMIM: 300160,300958) PREDICTED: ATP- ( 476) 270 65.0 8.2e-10 XP_011542194 (OMIM: 300160,300958) PREDICTED: ATP- ( 598) 270 65.1 9.9e-10 NP_001180346 (OMIM: 300160,300958) ATP-dependent R ( 646) 270 65.1 1e-09 NP_001180345 (OMIM: 300160,300958) ATP-dependent R ( 661) 270 65.1 1.1e-09 NP_001347 (OMIM: 300160,300958) ATP-dependent RNA ( 662) 270 65.1 1.1e-09 >>NP_004930 (OMIM: 601257) ATP-dependent RNA helicase DD (740 aa) initn: 5029 init1: 5029 opt: 5029 Z-score: 5459.1 bits: 1020.8 E(85289): 0 Smith-Waterman score: 5029; 100.0% identity (100.0% similar) in 740 aa overlap (1-740:1-740) 10 20 30 40 50 60 pF1KB5 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEK 670 680 690 700 710 720 730 740 pF1KB5 EAQTSFLHLGYLPNQLFRTF :::::::::::::::::::: NP_004 EAQTSFLHLGYLPNQLFRTF 730 740 >>NP_001309271 (OMIM: 616533) probable ATP-dependent RNA (674 aa) initn: 431 init1: 175 opt: 374 Z-score: 407.8 bits: 86.0 E(85289): 5.6e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:112-463) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. NP_001 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 90 100 110 120 130 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . NP_001 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 140 150 160 170 180 190 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . NP_001 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 200 210 220 230 240 250 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . NP_001 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 260 270 280 290 300 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . NP_001 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 310 320 330 340 350 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. NP_001 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 360 370 380 390 400 410 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : NP_001 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIK 420 430 440 450 460 470 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS NP_001 MEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKA 480 490 500 510 520 530 >>XP_006717299 (OMIM: 616533) PREDICTED: probable ATP-de (691 aa) initn: 485 init1: 175 opt: 374 Z-score: 407.7 bits: 86.0 E(85289): 5.7e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:289-640) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. XP_006 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . XP_006 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . XP_006 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . XP_006 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 430 440 450 460 470 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . XP_006 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. XP_006 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 540 550 560 570 580 590 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : XP_006 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINSAVLH 600 610 620 630 640 650 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS XP_006 PSLRHLPQGAEAHLPRPIPPPWACGEELRTKRCPQES 660 670 680 690 >>XP_011517224 (OMIM: 616533) PREDICTED: probable ATP-de (691 aa) initn: 485 init1: 175 opt: 374 Z-score: 407.7 bits: 86.0 E(85289): 5.7e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:289-640) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. XP_011 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . XP_011 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . XP_011 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . XP_011 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 430 440 450 460 470 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . XP_011 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. XP_011 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 540 550 560 570 580 590 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : XP_011 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINSAVLH 600 610 620 630 640 650 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS XP_011 PSLRHLPQGAEAHLPRPIPPPWACGEELRTKRCPQES 660 670 680 690 >>NP_001309272 (OMIM: 616533) probable ATP-dependent RNA (722 aa) initn: 485 init1: 175 opt: 374 Z-score: 407.4 bits: 86.0 E(85289): 5.9e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:160-511) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. NP_001 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 130 140 150 160 170 180 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . NP_001 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 190 200 210 220 230 240 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . NP_001 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 250 260 270 280 290 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . NP_001 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 300 310 320 330 340 350 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . NP_001 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 360 370 380 390 400 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. NP_001 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 410 420 430 440 450 460 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : NP_001 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIK 470 480 490 500 510 520 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS NP_001 MEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKA 530 540 550 560 570 580 >>NP_001309270 (OMIM: 616533) probable ATP-dependent RNA (755 aa) initn: 485 init1: 175 opt: 374 Z-score: 407.1 bits: 86.0 E(85289): 6.1e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:193-544) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. NP_001 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . NP_001 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . NP_001 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . NP_001 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 340 350 360 370 380 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . NP_001 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 390 400 410 420 430 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. NP_001 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 440 450 460 470 480 490 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : NP_001 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIK 500 510 520 530 540 550 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS NP_001 MEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKA 560 570 580 590 600 610 >>XP_005272264 (OMIM: 616533) PREDICTED: probable ATP-de (755 aa) initn: 485 init1: 175 opt: 374 Z-score: 407.1 bits: 86.0 E(85289): 6.1e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:193-544) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. XP_005 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . XP_005 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . XP_005 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . XP_005 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 340 350 360 370 380 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . XP_005 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 390 400 410 420 430 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. XP_005 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 440 450 460 470 480 490 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : XP_005 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIK 500 510 520 530 540 550 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS XP_005 MEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKA 560 570 580 590 600 610 >>XP_011517223 (OMIM: 616533) PREDICTED: probable ATP-de (787 aa) initn: 431 init1: 175 opt: 374 Z-score: 406.9 bits: 86.0 E(85289): 6.3e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:289-640) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. XP_011 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . XP_011 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . XP_011 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . XP_011 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 430 440 450 460 470 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . XP_011 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. XP_011 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 540 550 560 570 580 590 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : XP_011 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIK 600 610 620 630 640 650 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS XP_011 MEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKA 660 670 680 690 700 710 >>NP_073616 (OMIM: 616533) probable ATP-dependent RNA he (851 aa) initn: 431 init1: 175 opt: 374 Z-score: 406.4 bits: 86.0 E(85289): 6.8e-16 Smith-Waterman score: 382; 25.0% identity (59.8% similar) in 376 aa overlap (266-626:289-640) 240 250 260 270 280 290 pF1KB5 AELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPS .:.: .. .... .. ..: ::.. :. NP_073 KQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRS----DGPYALVLVPT 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 RELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRL-DDLV :::: :........ : . . ...:: ... . :..:..:...::::: : . NP_073 RELALQSFDTVQKLLKPFT--WIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIK 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFD :: ....:..:.::.:::: .:. :. :. . : :... .. : .. :::: . NP_073 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA---VNAECQKRQNVLLSATL-TEG 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 VKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGK-SHIRTDDVHAKD : .:.. .: :. . :: : : .::: . : . . :. . NP_073 VTRLADISLHDPVSI------SVLDKSHD---QLNPKDKAVQEVCPPPAGDKLDSFAIPE 430 440 450 460 470 480 490 500 510 520 pF1KB5 NTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE-------QYF . . .. . :. . . . .. : .. .. ..: . :. .: : . NP_073 SLKQHVTV--VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSS---CELVEFHYSLFLQTL 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB5 IQQGGGP-----DKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDI ....:.: . . ... . ::: . .:: ...:... :.::::::::.:. NP_073 LSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDL 540 550 560 570 580 590 590 600 610 620 630 640 pF1KB5 HGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA-TEKEKVWYHVCSSRGKGCYN : .... . :. .:.:::::..: : .. ..: .: : : NP_073 PQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIK 600 610 620 630 640 650 650 660 670 680 690 700 pF1KB5 TRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGS NP_073 MEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKA 660 670 680 690 700 710 >>NP_653333 (OMIM: 605800) heterogeneous nuclear ribonuc (756 aa) initn: 350 init1: 210 opt: 349 Z-score: 380.0 bits: 81.0 E(85289): 2e-14 Smith-Waterman score: 385; 25.4% identity (57.7% similar) in 366 aa overlap (97-439:127-469) 70 80 90 100 110 120 pF1KB5 TLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATK ::.:.. . .:. . : : ::. NP_653 PPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGF------AYLWSGARASY 100 110 120 130 140 150 130 140 150 160 170 pF1KB5 GLMKGKHYYEVSCH-------------DQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKK :. .:. .:.. . : . :.::: . : .:: . :..:.:::::: NP_653 GVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKK 160 170 180 190 200 210 180 190 200 210 220 pF1KB5 SHNKQFDNYGEEFTMHDTIGCYLDIDKGH---VKFSKNGKDLGLAFEIPPH-MKNQALFP : :..:.:::..:. .:.:::. :.. :. ..:.:::: .:.::.: . . .:::.: NP_653 STNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYP 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB5 ACVLKNAELKFNFGEEEFKF-PPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPK ..:: ..::::.. . ::. ... : . ... : . .. ..: NP_653 HVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGT-VGPKSKAECEIL----- 280 290 300 310 320 290 300 310 320 330 340 pF1KB5 ALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPG .. :. : .: ::. .::. .. :.: : :.. :. :. . : NP_653 MMVGLPA---AGKTTWAIKH---AASNPS-KKYNILGTNAIMDKMRVM--GLRRQRNYAG 330 340 350 360 370 350 360 370 380 390 400 pF1KB5 RLDDLVSTGKLNLSQ-VRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCS : : :.. . :.. ... . . . .:.: .. . . . . .: ...: NP_653 RWDVLIQQATQCLNRLIQIAARKKRNYILDQ--TNVYGSAQRRKMRPFEGFQRKAIVICP 380 390 400 410 420 430 410 420 430 440 450 460 pF1KB5 AT--LHSFDVKKLSEKIMHFP--TWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSH . :.. .:. .:. : . ...:.. ..:: NP_653 TDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQ 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB5 IRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE NP_653 YNEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGG 500 510 520 530 540 550 740 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:24:11 2016 done: Sat Nov 5 15:24:13 2016 Total Scan time: 10.870 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]