FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5747, 807 aa 1>>>pF1KB5747 807 - 807 aa - 807 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5970+/-0.000368; mu= 10.0217+/- 0.023 mean_var=134.5792+/-27.467, 0's: 0 Z-trim(117.3): 415 B-trim: 0 in 0/57 Lambda= 0.110557 statistics sampled from 28818 (29248) to 28818 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.343), width: 16 Scan time: 11.960 The best scores are: opt bits E(85289) NP_057051 (OMIM: 152700,180300,222100,600716) tyro ( 807) 5377 869.6 0 XP_016856493 (OMIM: 152700,180300,222100,600716) P ( 771) 5022 813.0 0 XP_011539524 (OMIM: 152700,180300,222100,600716) P ( 773) 4969 804.5 0 XP_016856494 (OMIM: 152700,180300,222100,600716) P ( 692) 4629 750.3 6.7e-216 XP_011539525 (OMIM: 152700,180300,222100,600716) P ( 715) 4532 734.8 3.1e-211 NP_001295226 (OMIM: 152700,180300,222100,600716) t ( 783) 4313 699.9 1.1e-200 NP_001180360 (OMIM: 152700,180300,222100,600716) t ( 779) 4296 697.2 7.2e-200 XP_011539527 (OMIM: 152700,180300,222100,600716) P ( 749) 3905 634.8 4.1e-181 XP_011539523 (OMIM: 152700,180300,222100,600716) P ( 781) 3497 569.7 1.7e-161 NP_036543 (OMIM: 152700,180300,222100,600716) tyro ( 752) 3316 540.9 7.9e-153 XP_016856495 (OMIM: 152700,180300,222100,600716) P ( 311) 2061 340.5 6.8e-93 NP_002826 (OMIM: 600079) tyrosine-protein phosphat ( 780) 1355 228.1 1.2e-58 NP_055184 (OMIM: 606587) tyrosine-protein phosphat ( 460) 954 164.0 1.3e-39 XP_006712480 (OMIM: 606587) PREDICTED: tyrosine-pr ( 464) 954 164.0 1.4e-39 NP_001124480 (OMIM: 600079) tyrosine-protein phosp ( 661) 867 150.2 2.7e-35 XP_006716136 (OMIM: 600079) PREDICTED: tyrosine-pr ( 748) 820 142.8 5.5e-33 XP_005250575 (OMIM: 600079) PREDICTED: tyrosine-pr ( 665) 819 142.6 5.5e-33 XP_016867963 (OMIM: 600079) PREDICTED: tyrosine-pr ( 665) 819 142.6 5.5e-33 NP_001124481 (OMIM: 600079) tyrosine-protein phosp ( 650) 804 140.2 2.9e-32 NP_563578 (OMIM: 151460,608971,609532) receptor-ty (1145) 690 122.1 1.4e-26 XP_006711537 (OMIM: 151460,608971,609532) PREDICTE (1192) 690 122.1 1.4e-26 XP_006711536 (OMIM: 151460,608971,609532) PREDICTE (1240) 690 122.1 1.5e-26 XP_006711535 (OMIM: 151460,608971,609532) PREDICTE (1258) 690 122.1 1.5e-26 NP_002829 (OMIM: 151460,608971,609532) receptor-ty (1306) 690 122.1 1.5e-26 XP_016873574 (OMIM: 600925) PREDICTED: receptor-ty (1321) 666 118.3 2.2e-25 NP_002834 (OMIM: 600925) receptor-type tyrosine-pr (1337) 666 118.3 2.2e-25 XP_016873573 (OMIM: 600925) PREDICTED: receptor-ty (1344) 666 118.3 2.2e-25 XP_016873572 (OMIM: 600925) PREDICTED: receptor-ty (1363) 666 118.3 2.2e-25 XP_006719057 (OMIM: 176883) PREDICTED: tyrosine-pr ( 481) 657 116.7 2.5e-25 NP_002822 (OMIM: 176883) tyrosine-protein phosphat ( 595) 657 116.7 3e-25 XP_011519290 (OMIM: 176883) PREDICTED: tyrosine-pr ( 597) 657 116.7 3e-25 NP_536858 (OMIM: 176883) tyrosine-protein phosphat ( 597) 657 116.7 3e-25 NP_536859 (OMIM: 176883) tyrosine-protein phosphat ( 624) 646 115.0 1.1e-24 XP_016883102 (OMIM: 608712) PREDICTED: receptor-ty (1436) 649 115.6 1.5e-24 NP_008981 (OMIM: 608712) receptor-type tyrosine-pr (1441) 649 115.6 1.5e-24 XP_016883101 (OMIM: 608712) PREDICTED: receptor-ty (1455) 649 115.6 1.6e-24 NP_573400 (OMIM: 608712) receptor-type tyrosine-pr (1460) 649 115.6 1.6e-24 XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368) 647 115.3 1.8e-24 NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439) 647 115.3 1.9e-24 NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440) 647 115.3 1.9e-24 XP_011534318 (OMIM: 602545) PREDICTED: receptor-ty (1456) 647 115.3 1.9e-24 XP_011524018 (OMIM: 176888) PREDICTED: receptor-ty (1239) 642 114.5 2.9e-24 XP_016881398 (OMIM: 176888) PREDICTED: receptor-ty (1248) 642 114.5 3e-24 XP_011524024 (OMIM: 176888) PREDICTED: receptor-ty (1252) 642 114.5 3e-24 XP_016881397 (OMIM: 176888) PREDICTED: receptor-ty (1264) 642 114.5 3e-24 XP_016881395 (OMIM: 176888) PREDICTED: receptor-ty (1277) 642 114.5 3e-24 XP_016881394 (OMIM: 176888) PREDICTED: receptor-ty (1428) 642 114.5 3.3e-24 XP_016881393 (OMIM: 176888) PREDICTED: receptor-ty (1447) 642 114.5 3.4e-24 NP_002836 (OMIM: 176888) receptor-type tyrosine-pr (1452) 642 114.5 3.4e-24 XP_016881392 (OMIM: 176888) PREDICTED: receptor-ty (1456) 642 114.5 3.4e-24 >>NP_057051 (OMIM: 152700,180300,222100,600716) tyrosine (807 aa) initn: 5377 init1: 5377 opt: 5377 Z-score: 4640.9 bits: 869.6 E(85289): 0 Smith-Waterman score: 5377; 100.0% identity (100.0% similar) in 807 aa overlap (1-807:1-807) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS 730 740 750 760 770 780 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI ::::::::::::::::::::::::::: NP_057 SSFLNFGFANRFSKPKGPRNPPPTWNI 790 800 >>XP_016856493 (OMIM: 152700,180300,222100,600716) PREDI (771 aa) initn: 5022 init1: 5022 opt: 5022 Z-score: 4335.2 bits: 813.0 E(85289): 0 Smith-Waterman score: 5022; 99.9% identity (99.9% similar) in 760 aa overlap (1-760:1-760) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 AVLATAPRIDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::::::::::::: XP_016 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKITLILWSFAVK 730 740 750 760 770 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI >>XP_011539524 (OMIM: 152700,180300,222100,600716) PREDI (773 aa) initn: 4965 init1: 4965 opt: 4969 Z-score: 4289.5 bits: 804.5 E(85289): 0 Smith-Waterman score: 4969; 97.5% identity (98.3% similar) in 772 aa overlap (1-772:1-771) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 AVLATAPRIDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::: .... . :. : :: XP_011 YSTSYPDTMENSTSSKQTLKTPGKSFTRSK-VSVILAHQTSLQNLFSQITPAHF 730 740 750 760 770 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI >>XP_016856494 (OMIM: 152700,180300,222100,600716) PREDI (692 aa) initn: 4629 init1: 4629 opt: 4629 Z-score: 3997.1 bits: 750.3 E(85289): 6.7e-216 Smith-Waterman score: 4629; 99.9% identity (99.9% similar) in 692 aa overlap (116-807:1-692) 90 100 110 120 130 140 pF1KB5 NANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAE :::::::::::::::::::::::::::::: XP_016 MIWEYSVLIIVMACMEYEMGKKKCERYWAE 10 20 30 150 160 170 180 190 200 pF1KB5 PGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPI 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB5 LELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREM 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB5 RTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSGTESQAKHCIPEKNHTLQADSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDKHSGTESQAKHCIPEKNHTLQADSYS 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB5 PNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNY 220 230 240 250 260 270 390 400 410 420 430 440 pF1KB5 SFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPIT 280 290 300 310 320 330 450 460 470 480 490 500 pF1KB5 RTKSTPFELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTKSTPFELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDS 340 350 360 370 380 390 510 520 530 540 550 560 pF1KB5 KHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSS 400 410 420 430 440 450 570 580 590 600 610 620 pF1KB5 LLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVRTPESF :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 LLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVWTPESF 460 470 480 490 500 510 630 640 650 660 670 680 pF1KB5 IVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSE 520 530 540 550 560 570 690 700 710 720 730 740 pF1KB5 LHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKS 580 590 600 610 620 630 750 760 770 780 790 800 pF1KB5 FTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKPKGPRNPPPTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKPKGPRNPPPTW 640 650 660 670 680 690 pF1KB5 NI :: XP_016 NI >>XP_011539525 (OMIM: 152700,180300,222100,600716) PREDI (715 aa) initn: 4579 init1: 4527 opt: 4532 Z-score: 3913.3 bits: 734.8 E(85289): 3.1e-211 Smith-Waterman score: 4532; 96.1% identity (97.4% similar) in 717 aa overlap (1-714:1-713) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 AVLATAPRIDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQ---DRSSPPPPLPERTLESFFLADEDCMQAQS ::::::::::::::::::::::::. .. . :: : . .: .. ::. XP_011 EPKKFDDSVILRPSKSVKLRSPKSDREKKGGNSSSRDQPTNDSKVEMSMM----CMEKW 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 IETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQS >>NP_001295226 (OMIM: 152700,180300,222100,600716) tyros (783 aa) initn: 4313 init1: 4313 opt: 4313 Z-score: 3723.9 bits: 699.9 E(85289): 1.1e-200 Smith-Waterman score: 5136; 97.0% identity (97.0% similar) in 807 aa overlap (1-807:1-783) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::: :::::::::::::::::::: NP_001 SVLIIVMACMEYEMGK------------------------EAEKRKSDYIIRTLKVKFNS 130 140 150 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS 700 710 720 730 740 750 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI ::::::::::::::::::::::::::: NP_001 SSFLNFGFANRFSKPKGPRNPPPTWNI 760 770 780 >>NP_001180360 (OMIM: 152700,180300,222100,600716) tyros (779 aa) initn: 4295 init1: 4295 opt: 4296 Z-score: 3709.3 bits: 697.2 E(85289): 7.2e-200 Smith-Waterman score: 5125; 96.5% identity (96.5% similar) in 807 aa overlap (1-807:1-779) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVK------------- 610 620 630 640 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------------SVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 650 660 670 680 690 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS 700 710 720 730 740 750 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI ::::::::::::::::::::::::::: NP_001 SSFLNFGFANRFSKPKGPRNPPPTWNI 760 770 >>XP_011539527 (OMIM: 152700,180300,222100,600716) PREDI (749 aa) initn: 3901 init1: 3901 opt: 3905 Z-score: 3372.5 bits: 634.8 E(85289): 4.1e-181 Smith-Waterman score: 4728; 94.4% identity (95.2% similar) in 772 aa overlap (1-772:1-747) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::: :::::::::::::::::::: XP_011 SVLIIVMACMEYEMGK------------------------EAEKRKSDYIIRTLKVKFNS 130 140 150 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 AVLATAPRIDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::: .... . :. : :: XP_011 YSTSYPDTMENSTSSKQTLKTPGKSFTRSK-VSVILAHQTSLQNLFSQITPAHF 700 710 720 730 740 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI >>XP_011539523 (OMIM: 152700,180300,222100,600716) PREDI (781 aa) initn: 3497 init1: 3497 opt: 3497 Z-score: 3020.5 bits: 569.7 E(85289): 1.7e-161 Smith-Waterman score: 5141; 96.7% identity (96.7% similar) in 807 aa overlap (1-807:1-781) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::: :::::::::::::::::::::::: XP_011 DYTWMLLKDG--------------------------EQYELVYNAVLELFKRQMDVIRDK 250 260 270 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 AVLATAPRIDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS 700 710 720 730 740 750 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI ::::::::::::::::::::::::::: XP_011 SSFLNFGFANRFSKPKGPRNPPPTWNI 760 770 780 >>NP_036543 (OMIM: 152700,180300,222100,600716) tyrosine (752 aa) initn: 5013 init1: 3316 opt: 3316 Z-score: 2864.8 bits: 540.9 E(85289): 7.9e-153 Smith-Waterman score: 4907; 93.2% identity (93.2% similar) in 807 aa overlap (1-807:1-752) 10 20 30 40 50 60 pF1KB5 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK :::::::::: NP_036 DYTWMLLKDG-------------------------------------------------- 250 310 320 330 340 350 360 pF1KB5 HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 -----SQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE 260 270 280 290 300 370 380 390 400 410 420 pF1KB5 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB5 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC 370 380 390 400 410 420 490 500 510 520 530 540 pF1KB5 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW 430 440 450 460 470 480 550 560 570 580 590 600 pF1KB5 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES 490 500 510 520 530 540 610 620 630 640 650 660 pF1KB5 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB5 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET 610 620 630 640 650 660 730 740 750 760 770 780 pF1KB5 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS 670 680 690 700 710 720 790 800 pF1KB5 SSFLNFGFANRFSKPKGPRNPPPTWNI ::::::::::::::::::::::::::: NP_036 SSFLNFGFANRFSKPKGPRNPPPTWNI 730 740 750 807 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:38:47 2016 done: Sat Nov 5 20:38:49 2016 Total Scan time: 11.960 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]