Result of FASTA (ccds) for
pF1KB5749
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5749, 808 aa
1>>>pF1KB5749 808 - 808 aa - 808 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8938+/-0.00133; mu= 4.3620+/- 0.080
mean_var=196.8769+/-39.121, 0's: 0 Z-trim(106.8): 30 B-trim: 0 in 0/51
Lambda= 0.091406
statistics sampled from 9173 (9192) to 9173 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.282), width: 16
Scan time: 3.540
The best scores are: opt bits E(32554)
CCDS4940.2 MCM3 gene_id:4172|Hs108|chr6 ( 853) 5211 700.7 2.5e-201
CCDS75468.1 MCM3 gene_id:4172|Hs108|chr6 ( 818) 4808 647.6 2.4e-185
CCDS3043.1 MCM2 gene_id:4171|Hs108|chr3 ( 904) 1064 153.9 1.1e-36
CCDS5683.1 MCM7 gene_id:4176|Hs108|chr7 ( 719) 1020 148.0 5.2e-35
CCDS5684.1 MCM7 gene_id:4176|Hs108|chr7 ( 543) 949 138.6 2.7e-32
CCDS13915.1 MCM5 gene_id:4174|Hs108|chr22 ( 734) 856 126.4 1.7e-28
CCDS56447.1 MCM9 gene_id:254394|Hs108|chr6 (1143) 768 114.9 7.7e-25
CCDS6143.1 MCM4 gene_id:4173|Hs108|chr8 ( 863) 752 112.7 2.6e-24
CCDS2179.1 MCM6 gene_id:4175|Hs108|chr2 ( 821) 750 112.5 3e-24
CCDS13095.1 MCM8 gene_id:84515|Hs108|chr20 ( 824) 704 106.4 2e-22
CCDS13094.1 MCM8 gene_id:84515|Hs108|chr20 ( 840) 588 91.1 8.3e-18
CCDS63227.1 MCM8 gene_id:84515|Hs108|chr20 ( 880) 525 82.8 2.7e-15
CCDS63226.1 MCM8 gene_id:84515|Hs108|chr20 ( 793) 420 68.9 3.7e-11
>>CCDS4940.2 MCM3 gene_id:4172|Hs108|chr6 (853 aa)
initn: 5211 init1: 5211 opt: 5211 Z-score: 3727.8 bits: 700.7 E(32554): 2.5e-201
Smith-Waterman score: 5211; 100.0% identity (100.0% similar) in 808 aa overlap (1-808:46-853)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEEDQG
::::::::::::::::::::::::::::::
CCDS49 REEFGSFRAGVESSWEPPRDFGGGSSLAAGMAGTVVLDDVELREAQRDYLDFLDDEEDQG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDAT
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 YAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 YAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 TKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 TKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPA
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 DAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 DAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLE
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB5 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 NGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGE
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB5 RRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 RRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLA
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB5 AANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 AANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAP
500 510 520 530 540 550
520 530 540 550 560 570
pF1KB5 GEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 GEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKK
560 570 580 590 600 610
580 590 600 610 620 630
pF1KB5 YIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 YIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAK
620 630 640 650 660 670
640 650 660 670 680 690
pF1KB5 ARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 ARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRK
680 690 700 710 720 730
700 710 720 730 740 750
pF1KB5 RRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 RRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVA
740 750 760 770 780 790
760 770 780 790 800
pF1KB5 LLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 LLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
800 810 820 830 840 850
>>CCDS75468.1 MCM3 gene_id:4172|Hs108|chr6 (818 aa)
initn: 4808 init1: 4808 opt: 4808 Z-score: 3440.9 bits: 647.6 E(32554): 2.4e-185
Smith-Waterman score: 4808; 100.0% identity (100.0% similar) in 745 aa overlap (64-808:74-818)
40 50 60 70 80 90
pF1KB5 SKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAK
::::::::::::::::::::::::::::::
CCDS75 LWQRAWRVPWCWTMWSCGRLREITWTSWTTRLLNNAFEELVAFQRALKDFVASIDATYAK
50 60 70 80 90 100
100 110 120 130 140 150
pF1KB5 QYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKK
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB5 TIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 TIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQL
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB5 PRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQ
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB5 PSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGS
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB5 HIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 HIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRL
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB5 EAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 EAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAAN
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 PVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQ
470 480 490 500 510 520
520 530 540 550 560 570
pF1KB5 DGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIH
530 540 550 560 570 580
580 590 600 610 620 630
pF1KB5 VAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 VAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARM
590 600 610 620 630 640
640 650 660 670 680 690
pF1KB5 SKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 SKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRK
650 660 670 680 690 700
700 710 720 730 740 750
pF1KB5 TRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 TRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLD
710 720 730 740 750 760
760 770 780 790 800
pF1KB5 VFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 VFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI
770 780 790 800 810
>>CCDS3043.1 MCM2 gene_id:4171|Hs108|chr3 (904 aa)
initn: 872 init1: 699 opt: 1064 Z-score: 771.9 bits: 153.9 E(32554): 1.1e-36
Smith-Waterman score: 1104; 33.4% identity (64.0% similar) in 677 aa overlap (10-679:193-830)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVREL
.:... ...: : . ..... .. ..
CCDS30 EDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDM
170 180 190 200 210 220
40 50 60 70 80 90
pF1KB5 ISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFY
..:. :.:: .:: ... : : . : : :..: . : .. : . ....
CCDS30 CKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIH
230 240 250 260 270 280
100 110 120 130 140 150
pF1KB5 VGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRY
: . ... :.: . :. .. . :.::.:. : :.. . : . ..
CCDS30 VRISHLPLVEEL--RSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFC
290 300 310 320 330 340
160 170 180 190 200 210
pF1KB5 SDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDV
.. . : :.: : . . .:.:... ..:...: : ::: : :. ::.:::: :.
CCDS30 QSQNQEVK-PGSC--P-ECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDA
350 360 370 380 390
220 230 240 250 260 270
pF1KB5 ILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSG--TFRTVLIACNV-KQMSKDAQPSF
:: ::::. ::::.....: :. . . ..: .: ::..: .: :. .: : .
CCDS30 ILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGEL
400 410 420 430 440 450
280 290 300 310 320 330
pF1KB5 SAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH-I
. ::. : ..:: ...: ... :.::::.::. .:... :.:: .. .:.: .
CCDS30 TDEDVKMITSLSK--DQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKV
460 470 480 490 500 510
340 350 360 370 380 390
pF1KB5 RGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEA
:::::.:: :::..::::.:.:. .. ::: :::.:.:.::::: : . : :::
CCDS30 RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEA
520 530 540 550 560 570
400 410 420 430 440 450
pF1KB5 GAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPV
::.::::::: :::::::.:.:::.:::.::: ..:.:::: . :.:::.:.:::::.
CCDS30 GALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPI
580 590 600 610 620 630
460 470 480 490 500 510
pF1KB5 YGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDG
:::: : ::. : . ..::::.: .. : .:: ::. .. :. : . :....
CCDS30 GGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEE
640 650 660 670 680 690
520 530 540 550 560 570
pF1KB5 DAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVA
... :::.. :: .:.. ... .:::: :
CCDS30 EGLANGSAAEPAM---PN------------------TYGVEPLPQEV-----LKKYIIYA
700 710 720
580 590 600 610 620 630
pF1KB5 KI-IKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMS
: ..: :.: . .:. :: :: ..::.. . :.:.: .:..::.: :::. ..
CCDS30 KERVHPKLNQMDQDKVAKMYSDLR-KESMATGSI---PITVRHIESMIRMAEAHARIHLR
730 740 750 760 770 780
640 650 660 670 680 690
pF1KB5 KTVDLQDAEEAVELVQYAYF--KKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRR
: .:.. :.... ... .: .. :: .. : .:..:
CCDS30 DYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQ
790 800 810 820 830 840
700 710 720 730 740 750
pF1KB5 KTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALL
CCDS30 VTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQ
850 860 870 880 890 900
>>CCDS5683.1 MCM7 gene_id:4176|Hs108|chr7 (719 aa)
initn: 866 init1: 780 opt: 1020 Z-score: 742.0 bits: 148.0 E(32554): 5.2e-35
Smith-Waterman score: 1093; 35.4% identity (62.1% similar) in 676 aa overlap (5-669:50-655)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEEDQ--GIY
: :::: : . . .: . .. . ..
CCDS56 FYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVA--EDDPELVDSICENARRYAKLF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 QSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKD--FVASIDAT
. :.::. . . : .:: . : :.: :. ::. .: .: : .
CCDS56 ADAVQELLPQYKEREVVNKDVLDVYIEHR-----------LMMEQRS-RDPGMVRSPQNQ
80 90 100 110 120
100 110 120 130 140
pF1KB5 Y-AKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCP
: :. ...: . ..: ..: : . . .. .: :.::::. : :.::.: ... :
CCDS56 YPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCD
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB5 AT-KKTIERRYSD-LTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEK
.: . : . :. ::. ... :.:. : : . : . .:: ..
CCDS56 QCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTR-G-SRFIKFQEMKMQEHSDQ
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB5 APAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY---TSGTF-RTVLIAC
.:.:..:::. :... . . :.:::.:.:.: . :: . :. ..: . .: : :
CCDS56 VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLEAH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB5 NVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLG
. .:.:. . .: .... ... . .:....:: :.:: :.::. ::::.: ::.:
CCDS56 RIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVG
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB5 GVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVT
::... : .:::.::: :.:::.::::::: :. :::. :::::::::::::::
CCDS56 GVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVL
370 380 390 400 410
390 400 410 420 430 440
pF1KB5 TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLN
:. .:: ::.::.::::.:: ::::::::.. ::::::::::: ..:::::: . ::
CCDS56 RDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB5 ARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLR
::::.::::::.::::. .. .:: : .::::::::... :. : ..: ....:.
CCDS56 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITY
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 MHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMV
.: :...: . .: : :
CCDS56 VH------------------------------QHSRQPPSQFEPLDMKL-----------
540 550
570 580 590 600 610 620
pF1KB5 SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIR
:..:: . . .:.. . : ::. : ..: . :.:.. :: :::: ...:
CCDS56 ----MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTS---ARTLLAILR
560 570 580 590 600 610
630 640 650 660 670 680
pF1KB5 LATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQE
:.:: :. :: .:. .:..::..:.... : : .: . :..
CCDS56 LSTALARLRMVDVVEKEDVNEAIRLMEMS--KDSLLGDKGQTARTQRPADVIFATVRELV
620 630 640 650 660
690 700 710 720 730 740
pF1KB5 DQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESR
CCDS56 SGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
670 680 690 700 710
>>CCDS5684.1 MCM7 gene_id:4176|Hs108|chr7 (543 aa)
initn: 821 init1: 735 opt: 949 Z-score: 693.2 bits: 138.6 E(32554): 2.7e-32
Smith-Waterman score: 1017; 38.7% identity (65.2% similar) in 509 aa overlap (165-669:27-479)
140 150 160 170 180 190
pF1KB5 SLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK
:. ::. ... :.:. : : .
CCDS56 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTR-G-SRFI
10 20 30 40 50
200 210 220 230 240 250
pF1KB5 DHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY---
: . .:: ...:.:..:::. :... . . :.:::.:.:.: . :: . :.
CCDS56 KFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQV
60 70 80 90 100 110
260 270 280 290 300 310
pF1KB5 TSGTF-RTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGH
..: . .: : : . .:.:. . .: .... ... . .:....:: :.:: :.::
CCDS56 VQGLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGH
120 130 140 150 160 170
320 330 340 350 360 370
pF1KB5 DYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTG
. ::::.: ::.:::... : .:::.::: :.:::.::::::: :. :::. :::
CCDS56 EDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG
180 190 200 210 220 230
380 390 400 410 420 430
pF1KB5 RGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGR
:::::::::::: :. .:: ::.::.::::.:: ::::::::.. :::::::::::
CCDS56 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQT
240 250 260 270 280 290
440 450 460 470 480 490
pF1KB5 VTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMD
..:::::: . ::::::.::::::.::::. .. .:: : .::::::::... :. :
CCDS56 ISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPD
300 310 320 330 340 350
500 510 520 530 540 550
pF1KB5 PEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDN
..: ....:. .: :...: . .: :
CCDS56 RDNDLRLAQHITYVH------------------------------QHSRQPPSQFEPLDM
360 370 380
560 570 580 590 600 610
pF1KB5 LLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART
: :..:: . . .:.. . : ::. : ..: . :.:.. :
CCDS56 KL---------------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYT
390 400 410 420
620 630 640 650 660 670
pF1KB5 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED
: :::: ...::.:: :. :: .:. .:..::..:.... : : .: . :..
CCDS56 S---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS--KDSLLGDKGQTARTQR
430 440 450 460 470 480
680 690 700 710 720 730
pF1KB5 ESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQE
CCDS56 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
490 500 510 520 530 540
>>CCDS13915.1 MCM5 gene_id:4174|Hs108|chr22 (734 aa)
initn: 868 init1: 625 opt: 856 Z-score: 625.0 bits: 126.4 E(32554): 1.7e-28
Smith-Waterman score: 995; 31.3% identity (58.1% similar) in 718 aa overlap (3-690:17-682)
10 20 30 40
pF1KB5 MAGTVVLDDVELREAQ--RDYLDFLDDEE---DQGIYQSKVRELIS
: . :. . :..: : . .:: . . :. . : :. ..
CCDS13 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
10 20 30 40 50 60
50 60 70 80 90
pF1KB5 DN----QYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALK---DFVASIDATYAKQ
. .: . :...:: .: :. : .. :.: ...: : : :. . .
CCDS13 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 YEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKT
... : :... .. : :.: : ..: .: . ::. : :: :..: : . ..:
CCDS13 LQDIQVMLKSD--ASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNT
130 140 150 160 170
160 170 180 190 200 210
pF1KB5 IER-RYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK---DHQTITIQEMPEKAPA
. . :.: . . . ::. . . : ::. .::.:. .:
CCDS13 LTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPH
180 190 200 210 220 230
220 230 240 250 260
pF1KB5 GQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRC----LPGKKG------GYTSGTFRTVL
:..:: ... : : ::. ::.:: ..: : : ..: : :. .:..
CCDS13 GEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 IACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCL
: .. ... . : .. ...... .... ..::.:::: : .:::: ::
CCDS13 IQVDTDGSGRSFAGAVSPQEEEEFRRLAAL--PNVYEVISKSIAPSIFGGTDMKKAIACL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB5 LLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTA
:.:: .. : .: :::::.:..:::..::::::..: .: .. :.:.:::..::::
CCDS13 LFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTA
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB5 AVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHA
.: : . . .:.::::::: ::::::::::: . ::.::::.::: ..:::::: .
CCDS13 SVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITT
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB5 RLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDH
::.::::::::: :.::.:. : .:: .. ..:::::..::. :. . :.: .. :
CCDS13 TLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKH
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB5 VLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKE
:. .: :. :. .:: : . .:
CCDS13 VITLH------------------VSALT------------QTQAVEGEIDL---------
540 550
570 580 590 600 610
pF1KB5 KMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRS---QDSMSSDTARTSPVTAR
: .::.: .. : :. :.: . ..: .:: : .:: . :.:.:
CCDS13 -----AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVR
560 570 580 590 600 610
620 630 640 650 660 670
pF1KB5 TLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETED
::...:.: : .: ... . :.:::..: : . . .: . . : . ::
CCDS13 QLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTLSGVEGFTSQED
620 630 640 650 660
680 690 700 710 720 730
pF1KB5 EEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQK
.: :. ... ::.
CCDS13 QEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRK
670 680 690 700 710 720
>>CCDS56447.1 MCM9 gene_id:254394|Hs108|chr6 (1143 aa)
initn: 593 init1: 278 opt: 768 Z-score: 559.5 bits: 114.9 E(32554): 7.7e-25
Smith-Waterman score: 820; 31.3% identity (57.5% similar) in 638 aa overlap (36-650:29-601)
10 20 30 40 50 60
pF1KB5 VLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRL
..: : .: ..::. : . : . .. .
CCDS56 MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYF
10 20 30 40 50
70 80 90 100 110
pF1KB5 LNNAF--EELVAFQRALKDFVASI-------DATYAKQYEEFYV-GLE--GSFGSKHVSP
: : : :. :. ::. . .: .:. :: . . :: . .:.
CCDS56 --NMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQNLHARISGLPVCPELVREHIPK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 RTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSV
.. ::: : : : . :::. . ..: :... . .:. .: :
CCDS56 TKDVGHFLS----VTGTVIRTSLVKVLEFERDYMCNKCKHVFVIK-ADFEQYYTFCRPSS
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 YPTKDE-ENNPLETEYGLSVY----KDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDK
:. . ... . ::: .:.: : :::. .. .:..:::. :::.:::::.
CCDS56 CPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 AKPGDRVQVVGTY--RCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAK-IK
: :: . . : : : .. . . :: : .. ..... . :.. : ..
CCDS56 CKSGDDLTIYGIVMQRWKPFQQD--VRCEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFE
240 250 260 270 280
290 300 310 320 330 340
pF1KB5 KFSKTRSKDIF---DQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINIL
: . ..: : . . :: :.. : :: :. .: ::..: .:...::. ..:
CCDS56 DFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 LIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLAD
:.:::...:::.:.:. .::.. ::: ::...::: ::. ...:: :::::.::::
CCDS56 LVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLT--VTAVKDSGEWNLEAGALVLAD
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB5 RGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQY
:. :::::..... :::.:::.::: ...::::. .::.: ..:::.:: :.::
CCDS56 AGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPQ
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB5 KTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGS
.. ::.: . :::::::....:: . . :: ::. .:
CCDS56 ESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFIL--------------------
470 480 490 500
530 540 550 560 570 580
pF1KB5 AVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVL
:.. : .:.::. : :: :. . . ..:.:
CCDS56 --------------ENK--------------GYPSKSEKLWSMEKMKTYFCLIRNLQPTL
510 520 530
590 600 610 620 630 640
pF1KB5 TQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDA
.. . . . :. :..: ..::: : : ::.::::: :::. . :: :.::
CCDS56 SDVGNQVLLRYYQMQRQSDC--RNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDA
540 550 560 570 580 590
650 660 670 680 690 700
pF1KB5 EEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDG
.: ...
CCDS56 ITVVSVMESSMQGGALLGGVNALHTSFPENPGEQYQRQCELILEKLELQSLLSEELRRLE
600 610 620 630 640 650
>>CCDS6143.1 MCM4 gene_id:4173|Hs108|chr8 (863 aa)
initn: 994 init1: 595 opt: 752 Z-score: 549.8 bits: 112.7 E(32554): 2.6e-24
Smith-Waterman score: 1005; 33.8% identity (61.0% similar) in 656 aa overlap (13-648:168-764)
10 20 30
pF1KB5 MAGTVVLDDVELREAQRDYLDFL-DDEEDQGI------YQSK
: :: ..: : .::. :: :...
CCDS61 DIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQR-FIDPLAKEEENVGIDITEPLYMQR
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB5 VRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQY
. :. .. : :: . .. ... .:.. : . .:. :.... .: : .
CCDS61 LGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIF--FD-RYPDSI
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB5 EEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTI
: . .. . : . :.:. .. .. . :.: . : . :.. .. : . .:
CCDS61 LEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTT
260 270 280 290 300 310
160 170 180 190 200 210
pF1KB5 ERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPR
: : .: :: . . .. . .. :...:.: : .:: :: :::: :.
CCDS61 -RVEMD-RGRIAEPSVC---GRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPH
320 330 340 350 360
220 230 240 250 260 270
pF1KB5 SVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSK-DAQP
.: .. .:::::..:::::.:.: :: .: . . .:.. . .: .. : ::.
CCDS61 TVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKR
370 380 390 400 410 420
280 290 300 310 320
pF1KB5 SFSAEDIAKIKKFSK---------TRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGV
. .. :. : ::. .:. ::...::..:::::. :. .::.:: :.::.
CCDS61 LHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGT
430 440 450 460 470 480
330 340 350 360 370 380
pF1KB5 ERDLENGSH--IRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVT
..:. . .. .:..::::: :::...:::::.:: .::. :.:.:::.::::: :
CCDS61 RKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVM
490 500 510 520 530 540
390 400 410 420 430 440
pF1KB5 TDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLN
: :: . :..::.::.: :. ::::::::.. :...:::::: ..:::::: .::
CCDS61 KDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLN
550 560 570 580 590 600
450 460 470 480 490 500
pF1KB5 ARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLR
:: ::::::::. .... :: .::: : .:::::::.:..:: .: ::... :..
CCDS61 ARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVA
610 620 630 640 650 660
510 520 530 540 550 560
pF1KB5 MHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMV
.. ...:.: . :...
CCDS61 LY----------------------------YQSEEQAE------------------EELL
670 680
570 580 590 600 610 620
pF1KB5 SAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLI
. : .: :: :. : : :..:.. . : : .:. : : . . : : ::.::
CCDS61 DMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGS-SRGMVSAYP---RQLESLI
690 700 710 720 730
630 640 650 660 670 680
pF1KB5 RLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQ
::: ::::.:.:. :. :.::: .:
CCDS61 RLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRK
740 750 760 770 780 790
>>CCDS2179.1 MCM6 gene_id:4175|Hs108|chr2 (821 aa)
initn: 971 init1: 743 opt: 750 Z-score: 548.7 bits: 112.5 E(32554): 3e-24
Smith-Waterman score: 1002; 31.1% identity (59.3% similar) in 695 aa overlap (8-655:20-658)
10 20 30 40
pF1KB5 MAGTVVLDDVELREAQRDYLDFLDDEE--DQGI-YQSKVRELISDNQY
:.: .. :. .::::.. . : : : . ..::: ..
CCDS21 MDLAAAAEPGAGSQHLEVRDEVA-EKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERN
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGS
:.:. ::.. :.. .. . .. .. . :::: :: : ..:::... .
CCDS21 TLVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVK--DRKEIPLAKDFYVAFQ-D
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 FGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTL
. ..: . : ::: .. .. . : :.. :.:..: .. : . .: : .
CCDS21 LPTRH-KIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVI--RDVEQQFK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 VAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDL
. :. :. .. : . . : . : : . ::: . : :..:::..::: .
CCDS21 YTQPNICRNPVCANRRRFL-LDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEA
180 190 200 210 220 230
230 240 250
pF1KB5 VDKAKPGDRVQVVGTYRCLP-------------------GKKGGYTSG------------
:..:. ::. . .:: .: : : : :
CCDS21 VESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDL
240 250 260 270 280 290
260 270 280 290 300
pF1KB5 TFRTVLIACNV---------KQMSKDAQPSFSAEDIAKIKKFSK----TRSKDIFDQLAK
..: :..:: : :.. . : . : .. .:.. : ...:... .:
CCDS21 SYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCT
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB5 SLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCT
:: :.:::.: ::...: .:.::: . .:. .:::::. ..::::.::::.:..:
CCDS21 SLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEF
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB5 APRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTA
.:::. :.:..::..::::::. :.:. : .::::..::: :: ::::::::. :..:
CCDS21 SPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVA
420 430 440 450 460 470
430 440 450 460 470 480
pF1KB5 IHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDL
:::.::: ..:.:::..: :::: :.::::::. :.::. :. .::.:. ..:::::
CCDS21 IHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDL
480 490 500 510 520 530
490 500 510 520 530 540
pF1KB5 LFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQD
.::..:. . : :. ... .: :. ...
CCDS21 FFILVDECNEVTDYAIARRIVDLH-----------------------------SRIEESI
540 550 560
550 560 570 580 590 600
pF1KB5 TQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQD
..: : ...:. :. .:: ...:: .:.:.:..::..:
CCDS21 DRVYSLDD------------------IRRYLLFARQFKPKISKESEDFIVEQYKHLRQRD
570 580 590 600
610 620 630 640 650 660
pF1KB5 SMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKE
. :. : . .:.: ::..:::. : :. . :. . ..:: .:.. . ..
CCDS21 G-SGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 KKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVH
CCDS21 NLDQEEEIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRIS
670 680 690 700 710 720
>>CCDS13095.1 MCM8 gene_id:84515|Hs108|chr20 (824 aa)
initn: 522 init1: 266 opt: 704 Z-score: 515.9 bits: 106.4 E(32554): 2e-22
Smith-Waterman score: 844; 31.1% identity (62.0% similar) in 547 aa overlap (114-654:208-733)
90 100 110 120 130 140
pF1KB5 VASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVR
... . . . . ..: :.. : ..: ..
CCDS13 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK
180 190 200 210 220 230
150 160 170 180 190 200
pF1KB5 SVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQE
. : : . : ..:.. :. .. :.: : :.: :::
CCDS13 MAFLCAACGEIQSFPLPDGK--YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQE
240 250 260 270 280 290
210 220 230 240 250 260
pF1KB5 M--PEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLI
. .. ::..::... : ::::. ::: : ..: . ..... :.. .
CCDS13 LMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANSISNS-KGQKT
300 310 320 330 340 350
270 280 290 300 310 320
pF1KB5 ACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLL
. .. :: .:. :.... ...: ...:: : : ::. :: .. :
CCDS13 KSSEDGCKHGMLMEFSLKDLYAIQEIQA--EENLFKLIVNSLCPVIFGHELVKAGLALAL
360 370 380 390 400 410
330 340 350 360 370
pF1KB5 LGGVER--DLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLT
.:: .. : .: :::: .::..:::...:::.:. . .:::.. . : .. :::
CCDS13 FGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLT
420 430 440 450 460 470
380 390 400 410 420 430
pF1KB5 AAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIH
.... :. .:. :::::.::.:.:. :::::::... . :. :.::: ...::::.
CCDS13 VTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVV
480 490 500 510 520 530
440 450 460 470 480 490
pF1KB5 ARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISD
: :: :..:::::: :.:.. :: ::. . ..:::::::.::.:: . ..:. .:.
CCDS13 CSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSE
540 550 560 570 580 590
500 510 520 530 540 550
pF1KB5 HVLRMHRYRAPGEQDGDAMPLGSA-VDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKK
::. . :: :.: ..:: : . ..: : : . . . .. ... :
CCDS13 HVIAI---RA-GKQR----TISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETID
600 610 620 630 640
560 570 580 590 600 610
pF1KB5 KEKMVSAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTART
. ...::: :. . : :. :.: . . : .::.: :. .::.:.:
CCDS13 P---IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQ----SQRLNSSPITTRQ
650 660 670 680 690
620 630 640 650 660 670
pF1KB5 LETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDE
::.::::. :.:. .. . . .:::. ::...:...
CCDS13 LESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSN
700 710 720 730 740 750
680 690 700 710 720 730
pF1KB5 EEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKV
CCDS13 RSTAKRFISALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGP
760 770 780 790 800 810
808 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:15:11 2016 done: Sat Nov 5 16:15:11 2016
Total Scan time: 3.540 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]