Result of FASTA (ccds) for
pF1KB5763
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5763, 816 aa
1>>>pF1KB5763 816 - 816 aa - 816 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.5533+/-0.00125; mu= -21.2258+/- 0.076
mean_var=850.4534+/-176.852, 0's: 0 Z-trim(117.7): 334 B-trim: 61 in 1/54
Lambda= 0.043979
statistics sampled from 18112 (18472) to 18112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.567), width: 16
Scan time: 5.490
The best scores are: opt bits E(32554)
CCDS11206.1 MAPK7 gene_id:5598|Hs108|chr17 ( 816) 5592 370.5 6.2e-102
CCDS11207.1 MAPK7 gene_id:5598|Hs108|chr17 ( 677) 4708 314.4 4.2e-85
CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 ( 379) 1158 88.8 1.8e-17
CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 ( 360) 1139 87.6 4e-17
CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 ( 357) 1084 84.1 4.5e-16
CCDS14090.1 MAPK11 gene_id:5600|Hs108|chr22 ( 364) 1062 82.7 1.2e-15
CCDS4816.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 1029 80.6 5.1e-15
CCDS4815.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 1019 80.0 7.9e-15
CCDS11224.2 NLK gene_id:51701|Hs108|chr17 ( 527) 948 75.7 2.3e-13
CCDS14089.1 MAPK12 gene_id:6300|Hs108|chr22 ( 367) 875 70.9 4.5e-12
CCDS6409.2 MAPK15 gene_id:225689|Hs108|chr8 ( 544) 859 70.0 1.2e-11
CCDS43410.1 MAPK9 gene_id:5601|Hs108|chr5 ( 382) 843 68.9 1.9e-11
CCDS4454.1 MAPK9 gene_id:5601|Hs108|chr5 ( 424) 843 68.9 2e-11
CCDS7224.1 MAPK8 gene_id:5599|Hs108|chr10 ( 427) 829 68.0 3.8e-11
CCDS42148.1 MAPK3 gene_id:5595|Hs108|chr16 ( 335) 825 67.7 3.8e-11
CCDS7225.1 MAPK8 gene_id:5599|Hs108|chr10 ( 384) 825 67.7 4.2e-11
CCDS43409.1 MAPK9 gene_id:5601|Hs108|chr5 ( 382) 814 67.0 6.7e-11
CCDS4817.1 MAPK14 gene_id:1432|Hs108|chr6 ( 307) 810 66.7 6.9e-11
CCDS4453.1 MAPK9 gene_id:5601|Hs108|chr5 ( 424) 814 67.1 7.2e-11
CCDS43247.1 MAPK10 gene_id:5602|Hs108|chr4 ( 422) 813 67.0 7.5e-11
CCDS3612.1 MAPK10 gene_id:5602|Hs108|chr4 ( 426) 813 67.0 7.6e-11
CCDS34026.1 MAPK10 gene_id:5602|Hs108|chr4 ( 464) 813 67.1 8.1e-11
CCDS7223.1 MAPK8 gene_id:5599|Hs108|chr10 ( 427) 808 66.7 9.5e-11
>>CCDS11206.1 MAPK7 gene_id:5598|Hs108|chr17 (816 aa)
initn: 5592 init1: 5592 opt: 5592 Z-score: 1943.5 bits: 370.5 E(32554): 6.2e-102
Smith-Waterman score: 5592; 100.0% identity (100.0% similar) in 816 aa overlap (1-816:1-816)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
730 740 750 760 770 780
790 800 810
pF1KB5 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::
CCDS11 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810
>>CCDS11207.1 MAPK7 gene_id:5598|Hs108|chr17 (677 aa)
initn: 4708 init1: 4708 opt: 4708 Z-score: 1641.3 bits: 314.4 E(32554): 4.2e-85
Smith-Waterman score: 4708; 100.0% identity (100.0% similar) in 677 aa overlap (140-816:1-677)
110 120 130 140 150 160
pF1KB5 KHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRG
::::::::::::::::::::::::::::::
CCDS11 MESDLHQIIHSSQPLTLEHVRYFLYQLLRG
10 20 30
170 180 190 200 210 220
pF1KB5 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 PELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 GAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 YHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB5 AISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAK
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB5 EREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAP
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB5 APAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 APAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPI
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB5 PVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPD
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB5 VNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQAD
580 590 600 610 620 630
770 780 790 800 810
pF1KB5 SASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
640 650 660 670
>>CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 (379 aa)
initn: 1074 init1: 601 opt: 1158 Z-score: 427.1 bits: 88.8 E(32554): 1.8e-17
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (49-389:36-372)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
:::: .: .. ::.::::.:::: ..
CCDS10 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
.:::::: . :. : .:::::..:: .:.:.:.:.:.:::: .. ...::.: :
CCDS10 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
:::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
CCDS10 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
:::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
CCDS10 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB5 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
: .::::.:. ::. :. .::.:: .. . ..: :.:::: . : : ..: .:
CCDS10 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB5 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
.::.:: ::: :.:. ::.. :: ::.: .:.:: ::: :: ::.. . : .::.:
CCDS10 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB5 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
: : : :.
CCDS10 ELIFQETARFQPGVLEAP
370
>>CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 (360 aa)
initn: 1043 init1: 590 opt: 1139 Z-score: 420.9 bits: 87.6 E(32554): 4e-17
Smith-Waterman score: 1139; 50.9% identity (76.3% similar) in 342 aa overlap (49-389:19-355)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
:::: .: . ::.::::.: :: ..
CCDS13 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNK
10 20 30 40
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILR-PTVPYGEFKSVYVVL
.:::::: . :. : .:::::.::: .:.:.:::.:.::.: ::. ..:.::.:
CCDS13 VRVAIKKI-SPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIE--QMKDVYIVQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB5 DLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELK
::::.::...... : :. .:. :::::.::::::.:::.:.::::::::::.: .:.::
CCDS13 DLMETDLYKLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 IGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA
: :::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
CCDS13 ICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB5 RRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD
: .::::.:. ::. :. .::.:: .. . ..: :. ::: .. :::. ..:.::
CCDS13 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERI
.::.:: .:: :.: :: . :: ::.: .:.::.::: :: : .. . : .:..
CCDS13 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB5 KEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPA
:: : : :.
CCDS13 KELIFEETARFQPGYRS
350 360
>>CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 (357 aa)
initn: 1015 init1: 542 opt: 1084 Z-score: 402.1 bits: 84.1 E(32554): 4.5e-16
Smith-Waterman score: 1084; 51.8% identity (78.0% similar) in 313 aa overlap (49-361:36-344)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
:::: .: .. ::.::::.:::: ..
CCDS42 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
.:::::: . :. : .:::::..:: .:.:.:.:.:.:::: .. ...::.: :
CCDS42 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
:::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
CCDS42 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
:::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
CCDS42 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB5 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
: .::::.:. ::. :. .::.:: .. . ..: :.:::: . : : ..: .:
CCDS42 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB5 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
.::.:: ::: :.:. ::.. :: ::.: .:.:: :: .:
CCDS42 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSPAAVGLGAGEQGGT
310 320 330 340 350
380 390 400 410 420 430
pF1KB5 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
>>CCDS14090.1 MAPK11 gene_id:5600|Hs108|chr22 (364 aa)
initn: 1081 init1: 545 opt: 1062 Z-score: 394.4 bits: 82.7 E(32554): 1.2e-15
Smith-Waterman score: 1062; 47.4% identity (75.3% similar) in 340 aa overlap (49-388:18-348)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
..: .. . .. .:.:::: : ::
CCDS14 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLR
10 20 30 40
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
:.::.::. :. . .:.:: :::..:::.::.:.:.. :.. :.. .:. ::.:
CCDS14 QKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTT
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB5 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
:: .::..:.. : :. :::....:::::::::.::: .:::::::::. :::.:::.:
CCDS14 LMGADLNNIVKC-QALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
:::.:: :... :: :::::::::::.::. .:.:..:.::::::..:.:
CCDS14 LDFGLAR-----QADEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQG
170 180 190 200 210
260 270 280 290 300 310
pF1KB5 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
. ::::..:. ::. :: :.::::: :. ...:..:.::::::: ... ::.
CCDS14 KALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
:..:::::: .. . :.::: :: : ....::::.:::. : :.: . . . : :. :
CCDS14 LAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE-AEPYDESVEAKERTLEEWK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
: :. .:
CCDS14 ELTYQEVLSFKPPEPPKPPGSLEIEQ
340 350 360
>>CCDS4816.1 MAPK14 gene_id:1432|Hs108|chr6 (360 aa)
initn: 783 init1: 489 opt: 1029 Z-score: 383.2 bits: 80.6 E(32554): 5.1e-15
Smith-Waterman score: 1029; 46.8% identity (74.4% similar) in 340 aa overlap (49-388:18-348)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
..: ..:. . .:.:::: : .: ::
CCDS48 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTG
10 20 30 40
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
.::.::. :. . .:::: :::..:::.::.:.:.. :.. :. ::..::.:
CCDS48 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB5 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
:: .::..:.. : :: .::....::.::::::.:::..:::::::::: :::.:::::
CCDS48 LMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
:::.:: . : :: :::::::::::.::. .:.:..:.::::::..:.:.
CCDS48 LDFGLARH---TDDE----MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTG
170 180 190 200 210
260 270 280 290 300 310
pF1KB5 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
: :::: ... ::.::. ..:::. ... ...: .: ::::: . . .:. ::.
CCDS48 RTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
:..:: .:: .. . ::.:: :: : ..:.:::::::: : :.: .:. . : .. :
CCDS48 LAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
:. .:
CCDS48 SLTYDEVISFVPPPLDQEEMES
340 350 360
>>CCDS4815.1 MAPK14 gene_id:1432|Hs108|chr6 (360 aa)
initn: 773 init1: 479 opt: 1019 Z-score: 379.7 bits: 80.0 E(32554): 7.9e-15
Smith-Waterman score: 1019; 47.1% identity (73.8% similar) in 340 aa overlap (49-388:18-348)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
..: ..:. . .:.:::: : .: ::
CCDS48 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTG
10 20 30 40
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
.::.::. :. . .:::: :::..:::.::.:.:.. :.. :. ::..::.:
CCDS48 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTH
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB5 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
:: .::..:.. : :: .::....::.::::::.:::..:::::::::: :::.:::::
CCDS48 LMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
:::.:: . : :: :::::::::::.::. .:.:..:.::::::..:.:.
CCDS48 LDFGLARH---TDDE----MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTG
170 180 190 200 210
260 270 280 290 300 310
pF1KB5 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
: :::: ....::: :: . ::: .:. . ....: ::::: . . .:. ::.
CCDS48 RTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
:..:: .:: .. . ::.:: :: : ..:.:::::::: : :.: .:. . : .. :
CCDS48 LAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP-VADPYDQSFESRDLLIDEWK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
:. .:
CCDS48 SLTYDEVISFVPPPLDQEEMES
340 350 360
>>CCDS11224.2 NLK gene_id:51701|Hs108|chr17 (527 aa)
initn: 928 init1: 361 opt: 948 Z-score: 353.3 bits: 75.7 E(32554): 2.3e-13
Smith-Waterman score: 968; 41.7% identity (66.6% similar) in 434 aa overlap (16-426:101-522)
10 20 30 40
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSF
. :::. : ::.. :..:: : . .:
CCDS11 AAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSH
80 90 100 110 120 130
50 60 70 80 90 100
pF1KB5 DVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKI
.. . : . :: ::.::: :. :..::.::.::.:. ... ::..::::.
CCDS11 HPQQQL--DIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKM
140 150 160 170 180
110 120 130 140 150 160
pF1KB5 LKHFKHDNIIAIKDILRPTVPYGE-FKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLY
: :::::... :::.: :. . :. .::: .::.::::.:: : :::. .::. :::
CCDS11 LCFFKHDNVLSALDILQP--PHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLY
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB5 QLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVAT
:.::::::.::: ..:::.::.::::: :: ::: :::.:: . ..: ::. :.:
CCDS11 QILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRH---MTQEVVT
250 260 270 280 290 300
230 240 250 260 270 280
pF1KB5 RWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPA
..:::::.... ..:..:::.:::::::.:.:.:: :: ... ..::.:: .:::::
CCDS11 QYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLE
310 320 330 340 350 360
290 300 310 320 330 340
pF1KB5 VIQAVGAERVRAYIQSLPPRQP-VP-WETVYPGADRQALSLLGRMLRFEPSARISAAAAL
..... : ..:.: : .:: .: :. : ..:. :: ::: :.:: :::: ::
CCDS11 AMRTA-CEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDAL
370 380 390 400 410 420
350 360 370 380
pF1KB5 RHPFLA----KYHD----------------PDDEPDCAPPFDFAFDREALTRERIKEAIV
::.: .:: : :: : :: .:... . ...:: :
CCDS11 AHPYLDEGRLRYHTCMCKCCFSTSTGRVYTSDFEPVTNPKFDDTFEKNLSSVRQVKEIIH
430 440 450 460 470 480
390 400 410 420 430 440
pF1KB5 AEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCP
: . ...: : . ..:. : . : .:: ::
CCDS11 QFILE---QQKGNRVPLCINPQSAAFKSFISST-VAQPSEMPPSPLVWE
490 500 510 520
450 460 470 480 490 500
pF1KB5 GPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAALLKSLRSRLRDGPSAPLEAP
>>CCDS14089.1 MAPK12 gene_id:6300|Hs108|chr22 (367 aa)
initn: 840 init1: 412 opt: 875 Z-score: 330.2 bits: 70.9 E(32554): 4.5e-12
Smith-Waterman score: 875; 39.7% identity (70.8% similar) in 343 aa overlap (55-396:27-360)
30 40 50 60 70 80
pF1KB5 PAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIK
:. .. .:.::::.: :: :: .::::
CCDS14 MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIK
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 KIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDL
:. :. :::. :::..:::..:.:.:.. :.. : .: . :.:. .: .::
CCDS14 KLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB5 HQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMA
.... . : .......::.:.::.:.:.: .:::::::.:: :::.::::: :::.:
CCDS14 GKLMKH-EKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLA
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB5 RGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPG
: :. . :: ::.::::::::..:. .:::..:.::::::..::.. . :: :
CCDS14 R-----QADSE--MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKG
180 190 200 210 220
270 280 290 300 310 320
pF1KB5 KNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLL
.... ::. :: : ::: .: . ..... :...:: . . .. .:. :..::
CCDS14 SDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLL
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB5 GRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAE
.:: .. :..:. :: ::.. . :: .:::. . .: .:: : .. :.. :
CCDS14 EKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQ-VQKYDDSFDDVDRTLDEWKRVTYKE
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB5 IEDFHARRE-GIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPG
. .:. :. : :
CCDS14 VLSFKPPRQLGARVSKETPL
350 360
816 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:17:16 2016 done: Sat Nov 5 16:17:17 2016
Total Scan time: 5.490 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]