Result of FASTA (omim) for
pF1KB5763
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5763, 816 aa
1>>>pF1KB5763 816 - 816 aa - 816 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.0877+/-0.000541; mu= -22.4788+/- 0.034
mean_var=1109.1789+/-239.374, 0's: 0 Z-trim(125.9): 520 B-trim: 3537 in 2/60
Lambda= 0.038510
statistics sampled from 49778 (50636) to 49778 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.594), width: 16
Scan time: 15.760
The best scores are: opt bits E(85289)
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 5592 326.9 2.3e-88
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 5592 326.9 2.3e-88
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 5592 326.9 2.3e-88
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 5570 325.6 5.3e-88
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 5570 325.6 5.3e-88
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 5570 325.6 5.3e-88
NP_620601 (OMIM: 602521) mitogen-activated protein ( 677) 4708 277.7 1.2e-73
XP_011522259 (OMIM: 602521) PREDICTED: mitogen-act ( 677) 4708 277.7 1.2e-73
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 1158 80.1 2e-14
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 1139 79.0 4.1e-14
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 1139 79.0 4.1e-14
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 1084 76.0 3.4e-13
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 1062 74.7 8e-13
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 1029 72.9 2.8e-12
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 1019 72.4 4.2e-12
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 976 70.0 2.3e-11
NP_057315 (OMIM: 609476) serine/threonine-protein ( 527) 948 68.6 8.1e-11
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 875 64.4 1.1e-09
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 860 63.4 1.6e-09
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297) 859 63.4 1.8e-09
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301) 859 63.4 1.8e-09
XP_016865788 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 859 63.4 1.9e-09
XP_016865789 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 849 62.9 2.7e-09
NP_620708 (OMIM: 602896) mitogen-activated protein ( 382) 843 62.6 3.8e-09
NP_620709 (OMIM: 602896) mitogen-activated protein ( 424) 843 62.7 4e-09
XP_016865127 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 843 62.7 4e-09
XP_011529008 (OMIM: 602898) PREDICTED: mitogen-act ( 256) 830 61.7 4.9e-09
XP_005258045 (OMIM: 609476) PREDICTED: serine/thre ( 498) 834 62.3 6.3e-09
NP_001310257 (OMIM: 601158) mitogen-activated prot ( 427) 829 61.9 7e-09
NP_001310260 (OMIM: 601158) mitogen-activated prot ( 427) 829 61.9 7e-09
NP_001310258 (OMIM: 601158) mitogen-activated prot ( 427) 829 61.9 7e-09
NP_620637 (OMIM: 601158) mitogen-activated protein ( 427) 829 61.9 7e-09
NP_001103361 (OMIM: 601795) mitogen-activated prot ( 335) 825 61.5 7e-09
NP_001310231 (OMIM: 601158) mitogen-activated prot ( 384) 825 61.6 7.6e-09
NP_001310256 (OMIM: 601158) mitogen-activated prot ( 384) 825 61.6 7.6e-09
NP_001310255 (OMIM: 601158) mitogen-activated prot ( 384) 825 61.6 7.6e-09
NP_001310253 (OMIM: 601158) mitogen-activated prot ( 384) 825 61.6 7.6e-09
XP_016865129 (OMIM: 602896) PREDICTED: mitogen-act ( 398) 819 61.3 9.8e-09
XP_016865793 (OMIM: 600289) PREDICTED: mitogen-act ( 258) 810 60.6 1.1e-08
XP_016865130 (OMIM: 602896) PREDICTED: mitogen-act ( 382) 814 61.0 1.2e-08
NP_620707 (OMIM: 602896) mitogen-activated protein ( 382) 814 61.0 1.2e-08
NP_620583 (OMIM: 600289) mitogen-activated protein ( 307) 810 60.7 1.2e-08
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 813 60.9 1.2e-08
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 813 60.9 1.2e-08
XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 813 60.9 1.2e-08
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 813 60.9 1.2e-08
XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 813 60.9 1.2e-08
XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 813 60.9 1.2e-08
XP_006714954 (OMIM: 602896) PREDICTED: mitogen-act ( 424) 814 61.1 1.2e-08
NP_002743 (OMIM: 602896) mitogen-activated protein ( 424) 814 61.1 1.2e-08
>>NP_620603 (OMIM: 602521) mitogen-activated protein kin (816 aa)
initn: 5592 init1: 5592 opt: 5592 Z-score: 1707.5 bits: 326.9 E(85289): 2.3e-88
Smith-Waterman score: 5592; 100.0% identity (100.0% similar) in 816 aa overlap (1-816:1-816)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
730 740 750 760 770 780
790 800 810
pF1KB5 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::
NP_620 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810
>>NP_002740 (OMIM: 602521) mitogen-activated protein kin (816 aa)
initn: 5592 init1: 5592 opt: 5592 Z-score: 1707.5 bits: 326.9 E(85289): 2.3e-88
Smith-Waterman score: 5592; 100.0% identity (100.0% similar) in 816 aa overlap (1-816:1-816)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
730 740 750 760 770 780
790 800 810
pF1KB5 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::
NP_002 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810
>>NP_620602 (OMIM: 602521) mitogen-activated protein kin (816 aa)
initn: 5592 init1: 5592 opt: 5592 Z-score: 1707.5 bits: 326.9 E(85289): 2.3e-88
Smith-Waterman score: 5592; 100.0% identity (100.0% similar) in 816 aa overlap (1-816:1-816)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
730 740 750 760 770 780
790 800 810
pF1KB5 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::
NP_620 WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810
>>XP_006721621 (OMIM: 602521) PREDICTED: mitogen-activat (822 aa)
initn: 5578 init1: 4744 opt: 5570 Z-score: 1700.8 bits: 325.6 E(85289): 5.3e-88
Smith-Waterman score: 5570; 99.3% identity (99.3% similar) in 822 aa overlap (1-816:1-822)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170
pF1KB5 LRPTVPYGEFKSV------YVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMH
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_006 LRPTVPYGEFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 PDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 TKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 PTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 PQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB5 QQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLS
730 740 750 760 770 780
780 790 800 810
pF1KB5 ASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::::::::
XP_006 ASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810 820
>>XP_006721622 (OMIM: 602521) PREDICTED: mitogen-activat (822 aa)
initn: 5578 init1: 4744 opt: 5570 Z-score: 1700.8 bits: 325.6 E(85289): 5.3e-88
Smith-Waterman score: 5570; 99.3% identity (99.3% similar) in 822 aa overlap (1-816:1-822)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170
pF1KB5 LRPTVPYGEFKSV------YVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMH
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_006 LRPTVPYGEFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 PDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 TKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 PTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 PQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB5 QQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLS
730 740 750 760 770 780
780 790 800 810
pF1KB5 ASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::::::::
XP_006 ASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810 820
>>XP_006721620 (OMIM: 602521) PREDICTED: mitogen-activat (822 aa)
initn: 5578 init1: 4744 opt: 5570 Z-score: 1700.8 bits: 325.6 E(85289): 5.3e-88
Smith-Waterman score: 5570; 99.3% identity (99.3% similar) in 822 aa overlap (1-816:1-822)
10 20 30 40 50 60
pF1KB5 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
70 80 90 100 110 120
130 140 150 160 170
pF1KB5 LRPTVPYGEFKSV------YVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMH
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_006 LRPTVPYGEFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 PDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 TKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 PTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 PQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB5 QQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLS
730 740 750 760 770 780
780 790 800 810
pF1KB5 ASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
::::::::::::::::::::::::::::::::::::::::::
XP_006 ASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
790 800 810 820
>>NP_620601 (OMIM: 602521) mitogen-activated protein kin (677 aa)
initn: 4708 init1: 4708 opt: 4708 Z-score: 1443.0 bits: 277.7 E(85289): 1.2e-73
Smith-Waterman score: 4708; 100.0% identity (100.0% similar) in 677 aa overlap (140-816:1-677)
110 120 130 140 150 160
pF1KB5 KHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRG
::::::::::::::::::::::::::::::
NP_620 MESDLHQIIHSSQPLTLEHVRYFLYQLLRG
10 20 30
170 180 190 200 210 220
pF1KB5 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 PELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 GAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 YHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 YHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB5 AISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAK
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB5 EREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 EREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAP
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB5 APAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 APAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPI
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB5 PVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPD
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB5 VNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQAD
580 590 600 610 620 630
770 780 790 800 810
pF1KB5 SASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
:::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
640 650 660 670
>>XP_011522259 (OMIM: 602521) PREDICTED: mitogen-activat (677 aa)
initn: 4708 init1: 4708 opt: 4708 Z-score: 1443.0 bits: 277.7 E(85289): 1.2e-73
Smith-Waterman score: 4708; 100.0% identity (100.0% similar) in 677 aa overlap (140-816:1-677)
110 120 130 140 150 160
pF1KB5 KHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRG
::::::::::::::::::::::::::::::
XP_011 MESDLHQIIHSSQPLTLEHVRYFLYQLLRG
10 20 30
170 180 190 200 210 220
pF1KB5 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 PELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 GAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 YHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 SEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPGCPDVEMPSPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDG
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB5 AISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISDNTKAALKAALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAK
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB5 EREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREKRRQERERKERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAP
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB5 APAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPI
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB5 PVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPD
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB5 VNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNLVTQQLSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQAD
580 590 600 610 620 630
770 780 790 800 810
pF1KB5 SASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
640 650 660 670
>>NP_002737 (OMIM: 601795) mitogen-activated protein kin (379 aa)
initn: 1074 init1: 601 opt: 1158 Z-score: 379.8 bits: 80.1 E(85289): 2e-14
Smith-Waterman score: 1158; 51.0% identity (76.5% similar) in 341 aa overlap (49-389:36-372)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
:::: .: .. ::.::::.:::: ..
NP_002 AQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRK
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLD
.:::::: . :. : .:::::..:: .:.:.:.:.:.:::: .. ...::.: :
NP_002 TRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAST-LEAMRDVYIVQD
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI
:::.::.....:.: :. .:. :::::.::::::.:::.:.::::::::::.: .:.:::
NP_002 LMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKI
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR
:::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
NP_002 CDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB5 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADR
: .::::.:. ::. :. .::.:: .. . ..: :.:::: . : : ..: .:
NP_002 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB5 QALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIK
.::.:: ::: :.:. ::.. :: ::.: .:.:: ::: :: ::.. . : .::.:
NP_002 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB5 EAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPAP
: : : :.
NP_002 ELIFQETARFQPGVLEAP
370
>>NP_002736 (OMIM: 176948) mitogen-activated protein kin (360 aa)
initn: 1043 init1: 590 opt: 1139 Z-score: 374.4 bits: 79.0 E(85289): 4.1e-14
Smith-Waterman score: 1139; 50.9% identity (76.3% similar) in 342 aa overlap (49-389:19-355)
20 30 40 50 60 70
pF1KB5 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
:::: .: . ::.::::.: :: ..
NP_002 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNK
10 20 30 40
80 90 100 110 120 130
pF1KB5 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILR-PTVPYGEFKSVYVVL
.:::::: . :. : .:::::.::: .:.:.:::.:.::.: ::. ..:.::.:
NP_002 VRVAIKKI-SPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIE--QMKDVYIVQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB5 DLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELK
::::.::...... : :. .:. :::::.::::::.:::.:.::::::::::.: .:.::
NP_002 DLMETDLYKLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 IGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA
: :::.:: . .: :.:::::::::::::.::. . ::..::.::::::..:::.
NP_002 ICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB5 RRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD
: .::::.:. ::. :. .::.:: .. . ..: :. ::: .. :::. ..:.::
NP_002 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERI
.::.:: .:: :.: :: . :: ::.: .:.::.::: :: : .. . : .:..
NP_002 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB5 KEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPA
:: : : :.
NP_002 KELIFEETARFQPGYRS
350 360
816 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:17:17 2016 done: Sat Nov 5 16:17:19 2016
Total Scan time: 15.760 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]