FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5768, 760 aa 1>>>pF1KB5768 760 - 760 aa - 760 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6836+/-0.000469; mu= 17.6688+/- 0.029 mean_var=74.1488+/-14.891, 0's: 0 Z-trim(109.3): 90 B-trim: 97 in 1/49 Lambda= 0.148944 statistics sampled from 17345 (17435) to 17345 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.554), E-opt: 0.2 (0.204), width: 16 Scan time: 11.090 The best scores are: opt bits E(85289) NP_004451 (OMIM: 600403) prolyl endopeptidase FAP ( 760) 5173 1121.9 0 XP_011509098 (OMIM: 600403) PREDICTED: prolyl endo ( 750) 4998 1084.3 0 NP_001278736 (OMIM: 600403) prolyl endopeptidase F ( 735) 4411 958.2 0 XP_011509099 (OMIM: 600403) PREDICTED: prolyl endo ( 491) 3334 726.7 5.6e-209 XP_016859074 (OMIM: 600403) PREDICTED: prolyl endo ( 475) 3220 702.2 1.3e-201 XP_005246428 (OMIM: 102720) PREDICTED: dipeptidyl ( 765) 2833 619.1 2.1e-176 NP_001926 (OMIM: 102720) dipeptidyl peptidase 4 [H ( 766) 2829 618.3 3.8e-176 NP_001308835 (OMIM: 608209) inactive dipeptidyl pe ( 789) 1620 358.5 6.2e-98 NP_001004360 (OMIM: 608209) inactive dipeptidyl pe ( 789) 1620 358.5 6.2e-98 NP_001171508 (OMIM: 608209) inactive dipeptidyl pe ( 792) 1620 358.5 6.3e-98 NP_065919 (OMIM: 608209) inactive dipeptidyl pepti ( 796) 1620 358.5 6.3e-98 NP_001171505 (OMIM: 608209) inactive dipeptidyl pe ( 800) 1620 358.5 6.3e-98 NP_001308834 (OMIM: 608209) inactive dipeptidyl pe ( 813) 1620 358.5 6.4e-98 NP_001308840 (OMIM: 608209) inactive dipeptidyl pe ( 746) 1603 354.8 7.5e-97 NP_001171507 (OMIM: 608209) inactive dipeptidyl pe ( 746) 1603 354.8 7.5e-97 NP_001308839 (OMIM: 608209) inactive dipeptidyl pe ( 746) 1603 354.8 7.5e-97 NP_001308837 (OMIM: 608209) inactive dipeptidyl pe ( 766) 1590 352.0 5.3e-96 XP_016860055 (OMIM: 608209) PREDICTED: inactive di ( 755) 1583 350.5 1.5e-95 NP_001308838 (OMIM: 608209) inactive dipeptidyl pe ( 757) 1550 343.4 2e-93 NP_001034439 (OMIM: 126141,612956,616311) dipeptid ( 801) 1536 340.4 1.7e-92 NP_001927 (OMIM: 126141,612956,616311) dipeptidyl ( 803) 1536 340.4 1.7e-92 XP_016867298 (OMIM: 126141,612956,616311) PREDICTE ( 804) 1536 340.4 1.7e-92 XP_016867297 (OMIM: 126141,612956,616311) PREDICTE ( 804) 1536 340.4 1.7e-92 XP_016867300 (OMIM: 126141,612956,616311) PREDICTE ( 804) 1536 340.4 1.7e-92 XP_016867299 (OMIM: 126141,612956,616311) PREDICTE ( 804) 1536 340.4 1.7e-92 NP_570629 (OMIM: 126141,612956,616311) dipeptidyl ( 865) 1536 340.4 1.8e-92 NP_001308841 (OMIM: 608209) inactive dipeptidyl pe ( 681) 1462 324.5 9.2e-88 XP_016867301 (OMIM: 126141,612956,616311) PREDICTE ( 657) 1369 304.5 9.2e-82 NP_001277181 (OMIM: 126141,612956,616311) dipeptid ( 758) 1326 295.3 6.3e-79 NP_001308843 (OMIM: 608209) inactive dipeptidyl pe ( 542) 1156 258.7 4.7e-68 NP_001308842 (OMIM: 608209) inactive dipeptidyl pe ( 542) 1156 258.7 4.7e-68 NP_001308836 (OMIM: 608209) inactive dipeptidyl pe ( 783) 944 213.2 3.3e-54 XP_016860054 (OMIM: 608209) PREDICTED: inactive di ( 776) 943 213.0 3.8e-54 XP_005254562 (OMIM: 606819) PREDICTED: dipeptidyl ( 479) 515 120.9 1.2e-26 XP_016877872 (OMIM: 606819) PREDICTED: dipeptidyl ( 514) 515 120.9 1.3e-26 XP_016877871 (OMIM: 606819) PREDICTED: dipeptidyl ( 514) 515 120.9 1.3e-26 XP_016877866 (OMIM: 606819) PREDICTED: dipeptidyl ( 781) 515 121.0 1.9e-26 XP_011520035 (OMIM: 606819) PREDICTED: dipeptidyl ( 824) 515 121.0 1.9e-26 XP_016877864 (OMIM: 606819) PREDICTED: dipeptidyl ( 839) 515 121.1 2e-26 XP_011520033 (OMIM: 606819) PREDICTED: dipeptidyl ( 840) 515 121.1 2e-26 XP_011520032 (OMIM: 606819) PREDICTED: dipeptidyl ( 855) 515 121.1 2e-26 NP_001307805 (OMIM: 606819) dipeptidyl peptidase 8 ( 882) 515 121.1 2.1e-26 NP_569118 (OMIM: 606819) dipeptidyl peptidase 8 is ( 882) 515 121.1 2.1e-26 XP_016877862 (OMIM: 606819) PREDICTED: dipeptidyl ( 898) 515 121.1 2.1e-26 NP_001307804 (OMIM: 606819) dipeptidyl peptidase 8 ( 898) 515 121.1 2.1e-26 NP_932064 (OMIM: 606819) dipeptidyl peptidase 8 is ( 898) 515 121.1 2.1e-26 XP_011526712 (OMIM: 608258) PREDICTED: dipeptidyl ( 863) 499 117.6 2.2e-25 XP_011526710 (OMIM: 608258) PREDICTED: dipeptidyl ( 892) 499 117.6 2.3e-25 XP_005259730 (OMIM: 608258) PREDICTED: dipeptidyl ( 892) 499 117.6 2.3e-25 NP_631898 (OMIM: 608258) dipeptidyl peptidase 9 [H ( 892) 499 117.6 2.3e-25 >>NP_004451 (OMIM: 600403) prolyl endopeptidase FAP isof (760 aa) initn: 5173 init1: 5173 opt: 5173 Z-score: 6005.5 bits: 1121.9 E(85289): 0 Smith-Waterman score: 5173; 100.0% identity (100.0% similar) in 760 aa overlap (1-760:1-760) 10 20 30 40 50 60 pF1KB5 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA 670 680 690 700 710 720 730 740 750 760 pF1KB5 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD :::::::::::::::::::::::::::::::::::::::: NP_004 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD 730 740 750 760 >>XP_011509098 (OMIM: 600403) PREDICTED: prolyl endopept (750 aa) initn: 4991 init1: 4991 opt: 4998 Z-score: 5802.4 bits: 1084.3 E(85289): 0 Smith-Waterman score: 4998; 98.8% identity (99.3% similar) in 740 aa overlap (21-760:11-750) 10 20 30 40 50 60 pF1KB5 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN ..: :. .::::::::::::::::::::::::::::: XP_011 MWNLFSMTYGLLCRPASPTYLHNSEENTMRALTLKDILNGTFSYKTFFPN 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB5 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB5 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB5 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA 660 670 680 690 700 710 730 740 750 760 pF1KB5 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD :::::::::::::::::::::::::::::::::::::::: XP_011 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD 720 730 740 750 >>NP_001278736 (OMIM: 600403) prolyl endopeptidase FAP i (735 aa) initn: 4406 init1: 4406 opt: 4411 Z-score: 5120.8 bits: 958.2 E(85289): 0 Smith-Waterman score: 4951; 96.7% identity (96.7% similar) in 760 aa overlap (1-760:1-735) 10 20 30 40 50 60 pF1KB5 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK ::::::::::::::::::::::::::::::::::: NP_001 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTM------------------------- 70 80 90 130 140 150 160 170 180 pF1KB5 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB5 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB5 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB5 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA 640 650 660 670 680 690 730 740 750 760 pF1KB5 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD :::::::::::::::::::::::::::::::::::::::: NP_001 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD 700 710 720 730 >>XP_011509099 (OMIM: 600403) PREDICTED: prolyl endopept (491 aa) initn: 3334 init1: 3334 opt: 3334 Z-score: 3872.8 bits: 726.7 E(85289): 5.6e-209 Smith-Waterman score: 3334; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KB5 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV ::: XP_011 TDQATSHCCHV 490 >>XP_016859074 (OMIM: 600403) PREDICTED: prolyl endopept (475 aa) initn: 3220 init1: 3220 opt: 3220 Z-score: 3740.6 bits: 702.2 E(85289): 1.3e-201 Smith-Waterman score: 3220; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467) 10 20 30 40 50 60 pF1KB5 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYVAEALKIS 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV >>XP_005246428 (OMIM: 102720) PREDICTED: dipeptidyl pept (765 aa) initn: 2516 init1: 1387 opt: 2833 Z-score: 3288.0 bits: 619.1 E(85289): 2.1e-176 Smith-Waterman score: 2833; 51.6% identity (80.7% similar) in 766 aa overlap (1-758:1-764) 10 20 30 40 50 60 pF1KB5 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPN ::: :...:. .:.:. .. :. .. ... .. .. :: : :..:. : . XP_005 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGNDATADSRKTYTLTDYLKNTYRLKLYSLR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 WISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNAS--NYGLSPDRQFVYLESDY ::: .:::... .:::...: : :.: ..: : :. . : .:..::: ::. :: .: XP_005 WISDHEYLYKQ-ENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGD : ::.::::.: ::::.. ... ...: :.. ::::: :::::..:.::.: .:. XP_005 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 PPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSY : ..::..:.:. :.::: :::::::.... :::::::: :::::.::::..:.: ::. XP_005 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YGDE--QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ---EVPVPAMIASSDYYF :.:: :::.:. .::::::: ::.:..:...: . : .. .:: . .:.:. XP_005 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 SWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVS .::.:.::. ::::.:.:: ::..:::. :. :.: ...::: : :::.: : : XP_005 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 TPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSN : :. :. :.:::.:...::.:: :.. .. ::.: ::.:.: .:.: :.: :: XP_005 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 EFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPI :.. .:: ::.:.:....: . :..:.: ::::::..::: :::: : : :::.:. XP_005 EYKGMPGGRNLYKIQLSDYT-KVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPL 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 STLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKK :::.. .:. ...::.:. :.. :.:.:.:.... . ..: .::.:::::.::.::: XP_005 YTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKK 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 YPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLG ::::..::.:::::.. .:: .:: .:::: :....: ::::...::::...:. :.:: XP_005 YPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLG 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 VYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSW ..:::::: :.:.: .:::.:.::::::::::::::.:..:.::.:.::::::::::: : XP_005 TFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 EYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQI ::: ::::::.::::: .:::.::.:::::.::: :..:.:::::::::::::::.:::: XP_005 EYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQI 660 670 680 690 700 710 720 730 740 750 760 pF1KB5 AKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHMTHFLKQCFSLSD .::::.. ::::::::.:..::. :. . .:.::::.::.:::::: XP_005 SKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 720 730 740 750 760 >>NP_001926 (OMIM: 102720) dipeptidyl peptidase 4 [Homo (766 aa) initn: 2522 init1: 1387 opt: 2829 Z-score: 3283.4 bits: 618.3 E(85289): 3.8e-176 Smith-Waterman score: 2829; 51.6% identity (80.6% similar) in 767 aa overlap (1-758:1-765) 10 20 30 40 50 pF1KB5 MKTWVKIVFGVATSAVLALLVMC-IVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFP ::: :...:. .:.:. .. .:: . . .. .. .. :: : :..:. : . NP_001 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 NWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNAS--NYGLSPDRQFVYLESD ::: .:::... .:::...: : :.: ..: : :. . : .:..::: ::. :: . NP_001 RWISDHEYLYKQ-ENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYN 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 YSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPG : : ::.::::.: ::::.. ... ...: :.. ::::: :::::..:.::.: .:. NP_001 YVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 DPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYS : ..::..:.:. :.::: :::::::.... :::::::: :::::.::::..:.: :: NP_001 LPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ---EVPVPAMIASSDYY .:.:: :::.:. .::::::: ::.:..:...: . : .. .:: . .:.: NP_001 FYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 FSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFV . .::.:.::. ::::.:.:: ::..:::. :. :.: ...::: : :::.: : NP_001 LCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 STPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSS : : :. :. :.:::.:...::.:: :.. .. ::.: ::.:.: .:.: :.: : NP_001 SEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYIS 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 NEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP ::.. .:: ::.:.:....: . :..:.: ::::::..::: :::: : : :::.: NP_001 NEYKGMPGGRNLYKIQLSDYT-KVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLP 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 ISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSK . :::.. .:. ...::.:. :.. :.:.:.:.... . ..: .::.:::::.::.:: NP_001 LYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSK 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 KYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKL :::::..::.:::::.. .:: .:: .:::: :....: ::::...::::...:. :.: NP_001 KYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRL 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 GVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS :..:::::: :.:.: .:::.:.::::::::::::::.:..:.::.:.::::::::::: NP_001 GTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 WEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQ :::: ::::::.::::: .:::.::.:::::.::: :..:.:::::::::::::::.::: NP_001 WEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQ 660 670 680 690 700 710 720 730 740 750 760 pF1KB5 IAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHMTHFLKQCFSLSD :.::::.. ::::::::.:..::. :. . .:.::::.::.:::::: NP_001 ISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 720 730 740 750 760 >>NP_001308835 (OMIM: 608209) inactive dipeptidyl peptid (789 aa) initn: 1490 init1: 632 opt: 1620 Z-score: 1879.2 bits: 358.5 E(85289): 6.2e-98 Smith-Waterman score: 1620; 34.1% identity (66.1% similar) in 768 aa overlap (10-756:27-774) 10 20 30 pF1KB5 MKTWVKIVFGVATSAVLALLVMC-------IVLRPSRVHNSEE :.: :.:..::.: :.: :... :: : NP_001 MRKVESRGEGGREELGSNSPPQRNWKGIAI-ALLVILVVCSLITMSVILLTPDELTNSSE 10 20 30 40 50 40 50 60 70 80 90 pF1KB5 NTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMK . :.:.:.. : . ::. . ...: ..... ::::. . .: : :. NP_001 TR---LSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFV 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB5 SVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGN--ELPRPI-QYL . .:: ...::: ..: : : .....:::::.: ::.. . : . : :. . :: NP_001 TFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB5 CWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALW :. :..: :...:::: . . ...: .:.:. ::::: ::.::::.: .. : : NP_001 AWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAHW 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 WSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPA :::.:. ::. .::. .:... . ::. . :::::: ::........ :. NP_001 WSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPT 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 YVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCP .. :. : . : .::.. . ::.. .. ..::.:.::.:.:..:. : : NP_001 HT--LELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETT----TGACS 300 310 320 330 340 350 340 350 360 370 380 pF1KB5 KTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDG----YKHIHY--IKDTVENA : : .. : . :::: :. ... :.: ..:: . :.. :. NP_001 KKYEMTSDT---WLSQQ-NEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKSEQI 360 370 380 390 400 390 400 410 420 430 440 pF1KB5 I--QITSGKWEAINIF---RVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCH ..:::.::.:.:. ..:: : :. : : :..: : . ...:..:. NP_001 TVRHLTSGNWEVIKILAYDETTQKIYFLST---ESSPRGRQLYSASTEGLL-NRQCISCN 410 420 430 440 450 460 450 460 470 480 490 500 pF1KB5 LRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQ . ::.: :. :::: . ... : : :: .:. .::. . . ::: :. :..:. . . NP_001 FMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKK 470 480 490 500 510 520 510 520 530 540 550 560 pF1KB5 LPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLA . : ::: :..:. : .. :: .: ..: ::. . : .: : . : ..: : : NP_001 IGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLI 530 540 550 560 570 580 570 580 590 600 610 620 pF1KB5 SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWG . .....: ::::..::: :.: ..:.:: ::.::::::. .... .:: ::..:.: NP_001 DMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFG 590 600 610 620 630 640 630 640 650 660 670 680 pF1KB5 WSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTV .::::..:. : : ::::: .:::... . :::...::..:.:.:... :. ..: NP_001 KGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQAASV 650 660 670 680 690 700 690 700 710 720 730 740 pF1KB5 MARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTN . .. ... . :.:::::: .::::.::.. : :..: :.. . : :..:..: : NP_001 LHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKY 710 720 730 740 750 760 750 760 pF1KB5 HLYTHMTHFLKQCFSLSD :::. . .:...:. NP_001 HLYSTILKFFSDCLKEEISVLPQEPEEDE 770 780 >>NP_001004360 (OMIM: 608209) inactive dipeptidyl peptid (789 aa) initn: 1490 init1: 632 opt: 1620 Z-score: 1879.2 bits: 358.5 E(85289): 6.2e-98 Smith-Waterman score: 1620; 34.1% identity (66.1% similar) in 768 aa overlap (10-756:27-774) 10 20 30 pF1KB5 MKTWVKIVFGVATSAVLALLVMC-------IVLRPSRVHNSEE :.: :.:..::.: :.: :... :: : NP_001 MRKVESRGEGGREELGSNSPPQRNWKGIAI-ALLVILVVCSLITMSVILLTPDELTNSSE 10 20 30 40 50 40 50 60 70 80 90 pF1KB5 NTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMK . :.:.:.. : . ::. . ...: ..... ::::. . .: : :. NP_001 TR---LSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFV 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB5 SVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGN--ELPRPI-QYL . .:: ...::: ..: : : .....:::::.: ::.. . : . : :. . :: NP_001 TFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB5 CWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALW :. :..: :...:::: . . ...: .:.:. ::::: ::.::::.: .. : : NP_001 AWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAHW 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 WSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPA :::.:. ::. .::. .:... . ::. . :::::: ::........ :. NP_001 WSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPT 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 YVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCP .. :. : . : .::.. . ::.. .. ..::.:.::.:.:..:. : : NP_001 HT--LELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETT----TGACS 300 310 320 330 340 350 340 350 360 370 380 pF1KB5 KTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDG----YKHIHY--IKDTVENA : : .. : . :::: :. ... :.: ..:: . :.. :. NP_001 KKYEMTSDT---WLSQQ-NEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKSEQI 360 370 380 390 400 390 400 410 420 430 440 pF1KB5 I--QITSGKWEAINIF---RVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCH ..:::.::.:.:. ..:: : :. : : :..: : . ...:..:. NP_001 TVRHLTSGNWEVIKILAYDETTQKIYFLST---ESSPRGRQLYSASTEGLL-NRQCISCN 410 420 430 440 450 460 450 460 470 480 490 500 pF1KB5 LRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQ . ::.: :. :::: . ... : : :: .:. .::. . . ::: :. :..:. . . NP_001 FMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKK 470 480 490 500 510 520 510 520 530 540 550 560 pF1KB5 LPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLA . : ::: :..:. : .. :: .: ..: ::. . : .: : . : ..: : : NP_001 IGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLI 530 540 550 560 570 580 570 580 590 600 610 620 pF1KB5 SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWG . .....: ::::..::: :.: ..:.:: ::.::::::. .... .:: ::..:.: NP_001 DMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFG 590 600 610 620 630 640 630 640 650 660 670 680 pF1KB5 WSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTV .::::..:. : : ::::: .:::... . :::...::..:.:.:... :. ..: NP_001 KGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQAASV 650 660 670 680 690 700 690 700 710 720 730 740 pF1KB5 MARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTN . .. ... . :.:::::: .::::.::.. : :..: :.. . : :..:..: : NP_001 LHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKY 710 720 730 740 750 760 750 760 pF1KB5 HLYTHMTHFLKQCFSLSD :::. . .:...:. NP_001 HLYSTILKFFSDCLKEEISVLPQEPEEDE 770 780 >>NP_001171508 (OMIM: 608209) inactive dipeptidyl peptid (792 aa) initn: 1490 init1: 632 opt: 1620 Z-score: 1879.1 bits: 358.5 E(85289): 6.3e-98 Smith-Waterman score: 1620; 34.1% identity (66.1% similar) in 768 aa overlap (10-756:30-777) 10 20 30 pF1KB5 MKTWVKIVFGVATSAVLALLVMC-------IVLRPSRVHN :.: :.:..::.: :.: :... : NP_001 MVITEVAEGPVDGSEKELGSNSPPQRNWKGIAI-ALLVILVVCSLITMSVILLTPDELTN 10 20 30 40 50 40 50 60 70 80 90 pF1KB5 SEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNR : :. :.:.:.. : . ::. . ...: ..... ::::. . .: : NP_001 SSETR---LSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB5 TMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGN--ELPRPI- :. . .:: ...::: ..: : : .....:::::.: ::.. . : . : :. . NP_001 TFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB5 QYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKY :: :. :..: :...:::: . . ...: .:.:. ::::: ::.::::.: .. NP_001 QYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHI 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 ALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTT : ::::.:. ::. .::. .:... . ::. . :::::: ::........ NP_001 AHWWSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLY 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 YPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTW :... :. : . : .::.. . ::.. .. ..::.:.::.:.:..:. : NP_001 GPTHT--LELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETT----TG 300 310 320 330 340 350 340 350 360 370 380 pF1KB5 DCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDG----YKHIHY--IKDTV : : : .. : . :::: :. ... :.: ..:: . :.. NP_001 ACSKKYEMTSDT---WLSQQ-NEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKS 360 370 380 390 400 390 400 410 420 430 pF1KB5 ENAI--QITSGKWEAINIF---RVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCV :. ..:::.::.:.:. ..:: : :. : : :..: : . ...:. NP_001 EQITVRHLTSGNWEVIKILAYDETTQKIYFLST---ESSPRGRQLYSASTEGLL-NRQCI 410 420 430 440 450 460 440 450 460 470 480 490 pF1KB5 TCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALK .:.. ::.: :. :::: . ... : : :: .:. .::. . . ::: :. :..:. NP_001 SCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAIL 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB5 NIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWIS . .. : ::: :..:. : .. :: .: ..: ::. . : .: : . : ..: : NP_001 KKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDS 530 540 550 560 570 580 560 570 580 590 600 610 pF1KB5 YLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIA : . .....: ::::..::: :.: ..:.:: ::.::::::. .... .:: ::.. NP_001 VLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLS 590 600 610 620 630 640 620 630 640 650 660 670 pF1KB5 IWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKN :.: .::::..:. : : ::::: .:::... . :::...::..:.:.:... :. NP_001 IFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQA 650 660 670 680 690 700 680 690 700 710 720 730 pF1KB5 STVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGL ..:. .. ... . :.:::::: .::::.::.. : :..: :.. . : :..:..: NP_001 ASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEK 710 720 730 740 750 760 740 750 760 pF1KB5 STNHLYTHMTHFLKQCFSLSD : :::. . .:...:. NP_001 SKYHLYSTILKFFSDCLKEEISVLPQEPEEDE 770 780 790 760 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:57:51 2016 done: Sat Nov 5 07:57:53 2016 Total Scan time: 11.090 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]