FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5769, 750 aa 1>>>pF1KB5769 750 - 750 aa - 750 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6637+/-0.000851; mu= 5.8203+/- 0.051 mean_var=193.8504+/-38.948, 0's: 0 Z-trim(114.4): 120 B-trim: 82 in 2/49 Lambda= 0.092117 statistics sampled from 14831 (14960) to 14831 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.46), width: 16 Scan time: 5.010 The best scores are: opt bits E(32554) CCDS81705.1 ARHGAP9 gene_id:64333|Hs108|chr12 ( 821) 5135 695.1 1.1e-199 CCDS44929.1 ARHGAP9 gene_id:64333|Hs108|chr12 ( 640) 3056 418.7 1.4e-116 CCDS8941.2 ARHGAP9 gene_id:64333|Hs108|chr12 ( 731) 3056 418.8 1.5e-116 CCDS44928.1 ARHGAP9 gene_id:64333|Hs108|chr12 ( 547) 1954 272.2 1.5e-72 CCDS11498.1 ARHGAP27 gene_id:201176|Hs108|chr17 ( 548) 463 74.1 6.6e-13 CCDS74082.1 ARHGAP27 gene_id:201176|Hs108|chr17 ( 889) 463 74.2 9.7e-13 CCDS2184.1 ARHGAP15 gene_id:55843|Hs108|chr2 ( 475) 445 71.7 3.1e-12 >>CCDS81705.1 ARHGAP9 gene_id:64333|Hs108|chr12 (821 aa) initn: 5135 init1: 5135 opt: 5135 Z-score: 3698.3 bits: 695.1 E(32554): 1.1e-199 Smith-Waterman score: 5135; 99.9% identity (100.0% similar) in 750 aa overlap (1-750:72-821) 10 20 30 pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCAL :::::::::::::::::::::::::::::: CCDS81 EEWPDSHHYPGPTPAPESSDGPHKVTVLATMLSSRWWPSSWGILGLGPRSPPRGSQLCAL 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB5 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPS 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB5 QSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSP 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB5 SFLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPAC :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPAC 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB5 PLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVL 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB5 QPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLN 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB5 MTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAAL 410 420 430 440 450 460 400 410 420 430 440 450 pF1KB5 AHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 AHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTG 470 480 490 500 510 520 460 470 480 490 500 510 pF1KB5 RDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN 530 540 550 560 570 580 520 530 540 550 560 570 pF1KB5 RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRG 590 600 610 620 630 640 580 590 600 610 620 630 pF1KB5 LDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVV 650 660 670 680 690 700 640 650 660 670 680 690 pF1KB5 TGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLE 710 720 730 740 750 760 700 710 720 730 740 750 pF1KB5 HLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 HLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP 770 780 790 800 810 820 >>CCDS44929.1 ARHGAP9 gene_id:64333|Hs108|chr12 (640 aa) initn: 3050 init1: 3050 opt: 3056 Z-score: 2206.6 bits: 418.7 E(32554): 1.4e-116 Smith-Waterman score: 4331; 97.0% identity (97.1% similar) in 658 aa overlap (1-658:1-639) 10 20 30 40 50 60 pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS44 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE ::::::::::::::::: :::::::::::::::::::::::: CCDS44 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE 430 440 450 460 490 500 510 520 530 540 pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP >>CCDS8941.2 ARHGAP9 gene_id:64333|Hs108|chr12 (731 aa) initn: 3050 init1: 3050 opt: 3056 Z-score: 2205.8 bits: 418.8 E(32554): 1.5e-116 Smith-Waterman score: 4953; 97.3% identity (97.5% similar) in 750 aa overlap (1-750:1-731) 10 20 30 40 50 60 pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: CCDS89 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE ::::::::::::::::: :::::::::::::::::::::::: CCDS89 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE 430 440 450 460 490 500 510 520 530 540 pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP 650 660 670 680 690 700 730 740 750 pF1KB5 EQETSDPAAHALYPGQLVQLMLTNFTSLFP :::::::::::::::::::::::::::::: CCDS89 EQETSDPAAHALYPGQLVQLMLTNFTSLFP 710 720 730 >>CCDS44928.1 ARHGAP9 gene_id:64333|Hs108|chr12 (547 aa) initn: 1954 init1: 1954 opt: 1954 Z-score: 1416.1 bits: 272.2 E(32554): 1.5e-72 Smith-Waterman score: 3693; 96.6% identity (96.6% similar) in 566 aa overlap (185-750:1-547) 160 170 180 190 200 210 pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ :::::::::::::::::::::::::::::: CCDS44 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ 10 20 30 220 230 240 250 260 270 pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA 40 50 60 70 80 90 280 290 300 310 320 330 pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG ::::::::::::::::::::::::::::::::::::::::::: CCDS44 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERL----------------- 220 230 240 250 460 470 480 490 500 510 pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 --DRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN 260 270 280 290 300 310 520 530 540 550 560 570 pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD 320 330 340 350 360 370 580 590 600 610 620 630 pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL 380 390 400 410 420 430 640 650 660 670 680 690 pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR 440 450 460 470 480 490 700 710 720 730 740 750 pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP 500 510 520 530 540 >>CCDS11498.1 ARHGAP27 gene_id:201176|Hs108|chr17 (548 aa) initn: 999 init1: 461 opt: 463 Z-score: 345.2 bits: 74.1 E(32554): 6.6e-13 Smith-Waterman score: 1095; 36.3% identity (59.9% similar) in 604 aa overlap (171-750:13-546) 150 160 170 180 190 pF1KB5 RSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEP-----PVYCNLV : . : :. : : : :: CCDS11 MQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGE 10 20 30 40 200 210 220 230 240 pF1KB5 DLRRCPRSPPPGPACPLLQ----------RLDAWEQHLDPNSGRCFYINSLTGCKSWKPP : . ::: .: . : . : . ::. :. .. : . :. : CCDS11 PGPTSPLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPH-GKPYFYNPEDSSVRWELP 50 60 70 80 90 100 250 260 270 280 290 300 pF1KB5 RRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPP . : :.. : ..: : :.. . .: :: :: ...: : CCDS11 QVPVP--APRSIH-----KSSQDGDTP-AQASPPEEKVPAELDEVGSW---EEVS----P 110 120 130 140 310 320 330 340 350 360 pF1KB5 ALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRK-NWGPSWVVLTGNSLVFYREPP : : : . :: :.:.:. :: :. :..::: .:. ::.:: :. :.:... CCDS11 ATAAVRT--KTLD------KAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSK 150 160 170 180 190 370 380 390 400 410 420 pF1KB5 PTAPSSGWGPAG-SRPESSVDLRGAALAHG-RHLSSRRNVLHIRTIPGHEFLLQSDHETE .: .. :. : :: .:.::::.:. . . :::.:::..:. : :.:.: : :. CCDS11 TSAAGGLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAI 200 210 220 230 240 250 430 440 450 460 470 480 pF1KB5 LRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDEEE . .::.:. :..: . .. . : ::..: . : : ::. CCDS11 ISTWHKAIAQGIQELSAELPPEESESSRVDFGSSERLG--------------SWQEKEED 260 270 280 290 300 490 500 510 520 530 540 pF1KB5 ESELVSKPLLRLSSRRSSIRGPEGTEQN--RVRNKLKRLIAKRPPLQSLQERGLLRDQVF .. : : :: : :.. .::.::.... .:: ::::.:.: ..:::: CCDS11 ARPNAAAPAL----------GPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVF 310 320 330 340 350 550 560 570 580 590 600 pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT :: : .::.:: . :: :.. :: ::. ::::.::.::.:::::..::::. ::... CCDS11 GCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDE--- 360 370 380 390 400 410 610 620 630 640 650 pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFR---AA :::::. .:.:.::.:::::::.::::.:: : . ::: :: CCDS11 ---------------RLDLDDGRWEDVHVITGALKLFFRELPEPLFP---FSHFRQFIAA 420 430 440 450 660 670 680 690 700 710 pF1KB5 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL . :... . ...:. :.: :::::::.:..:::::: :...:::. ....::::::: CCDS11 IKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTL 460 470 480 490 500 510 720 730 740 750 pF1KB5 FRPE-QETSDPAAHALYPGQLVQLMLTNFTSLFP .::: .::: : . .. .:.:.:.: . ...:: CCDS11 LRPEVEETSMPMTM-VFQNQVVELILQQCADIFPPH 520 530 540 >>CCDS74082.1 ARHGAP27 gene_id:201176|Hs108|chr17 (889 aa) initn: 1168 init1: 461 opt: 463 Z-score: 342.2 bits: 74.2 E(32554): 9.7e-13 Smith-Waterman score: 1096; 35.8% identity (59.6% similar) in 614 aa overlap (158-750:341-887) 130 140 150 160 170 180 pF1KB5 SSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSE : : : .. : . : :. : : CCDS74 EESRRVFFYNPLTGETAWEDEAENEPEEELEMQPGLSPGSPGDPRPPTPETDYPESLTSY 320 330 340 350 360 370 190 200 210 220 230 pF1KB5 P-----PVYCNLVDLRRCPRSPPPGPACPLLQ----------RLDAWEQHLDPNSGRCFY : :: : . ::: .: . : . : . ::. :. .. CCDS74 PEEDYSPVGSFGEPGPTSPLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPH-GKPYF 380 390 400 410 420 240 250 260 270 280 290 pF1KB5 INSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGS : . :. :. : :.. : ..: : :.. . .: :: :: CCDS74 YNPEDSSVRWELPQVPVPA--PRSIH-----KSSQDGDTP-AQASPPEEKVPAELDEVGS 430 440 450 460 470 480 300 310 320 330 340 350 pF1KB5 LSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRK-NWGPSWVV ...: :: : : . :: :.:.:. :: :. :..::: .:. ::.: CCDS74 W---EEVS----PATAAVR--TKTLD------KAGVLHRTKTADKGKRLRKKHWSASWTV 490 500 510 520 360 370 380 390 400 pF1KB5 LTGNSLVFYREPPPTAPSSGWGPAG-SRPESSVDLRGAALAHG-RHLSSRRNVLHIRTIP : :. :.:... .: .. :. : :: .:.::::.:. . . :::.:::..:. CCDS74 LEGGVLTFFKDSKTSAAGGLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRD 530 540 550 560 570 580 410 420 430 440 450 460 pF1KB5 GHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGS : :.:.: : :. . .::.:. :..: . .. . : ::..: . CCDS74 GSEYLIQHDSEAIISTWHKAIAQGIQELSAELPPEESESSRVDFGSSERLG--------- 590 600 610 620 630 470 480 490 500 510 520 pF1KB5 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN--RVRNKLKRLIAKRPPLQ : : ::. .. : : :: : :.. .::.::.... .:: :: CCDS74 -----SWQEKEEDARPNAAAPAL----------GPVGLESDLSKVRHKLRKFLQRRPTLQ 640 650 660 670 680 530 540 550 560 570 580 pF1KB5 SLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQ ::.:.: ..:::::: : .::.:: . :: :.. :: ::. ::::.::.::.:::::..: CCDS74 SLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQ 690 700 710 720 730 740 590 600 610 620 630 640 pF1KB5 KLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVP :::. ::... :::::. .:.:.::.:::::::.::::.:: : CCDS74 KLRYKVDHDE------------------RLDLDDGRWEDVHVITGALKLFFRELPEPLFP 750 760 770 780 650 660 670 680 690 700 pF1KB5 PLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPH . .: ::. :... . ...:. :.: :::::::.:..:::::: :...:::. . CCDS74 FSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQ 790 800 810 820 830 840 710 720 730 740 750 pF1KB5 NLGIVFGPTLFRPE-QETSDPAAHALYPGQLVQLMLTNFTSLFP ...:::::::.::: .::: : . .. .:.:.:.: . ...:: CCDS74 SVAIVFGPTLLRPEVEETSMPMTM-VFQNQVVELILQQCADIFPPH 850 860 870 880 >>CCDS2184.1 ARHGAP15 gene_id:55843|Hs108|chr2 (475 aa) initn: 1134 init1: 445 opt: 445 Z-score: 333.1 bits: 71.7 E(32554): 3.1e-12 Smith-Waterman score: 1104; 42.1% identity (71.7% similar) in 442 aa overlap (312-749:74-470) 290 300 310 320 330 340 pF1KB5 GTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKL :: ::. ::: : :. .:::.::.:: CCDS21 MILTDVGKVTEPISRHRRNHSQHILKDVIPPLEQLM-----VEKEGYLQKAKIADGGKKL 50 60 70 80 90 350 360 370 380 390 400 pF1KB5 RKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRN ::::. ::.::.. . ::.: : :. .: .::: ::: :: . ... :::.: CCDS21 RKNWSTSWIVLSSRRIEFYKESKQQALSNM--KTGHKPES-VDLCGAHIEWAKEKSSRKN 100 110 120 130 140 150 410 420 430 440 450 460 pF1KB5 VLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENP :..: :. :.::::::: . . : .:....:.:: : .:.. .:. CCDS21 VFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRL----------P--KDSSCPSRN-- 160 170 180 190 200 470 480 490 500 510 pF1KB5 LEL-RLSGSGPAELSAGED---EEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLK ::: ... :. .:: . : .:.. : .. ..:: : . ...:::...:: CCDS21 LELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSAS-----DTSDKNRVKSRLK 210 220 230 240 250 520 530 540 550 560 570 pF1KB5 RLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIY ..:..:: :..:::.::..::.:: .:...:.::..::: :.. :: ::.:::::::::: CCDS21 KFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIY 260 270 280 290 300 310 580 590 600 610 620 630 pF1KB5 RVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLF :::::::..:::::.:. :: .:.::...:.::::::::::.: CCDS21 RVSGNLATIQKLRFIVN------------------QEEKLNLDDSQWEDIHVVTGALKMF 320 330 340 350 640 650 660 670 680 690 pF1KB5 LRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIA .::::.:: : .. .: :. .... . .. :. ..: ::.::.. :. :: ...: CCDS21 FRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVA 360 370 380 390 400 410 700 710 720 730 740 750 pF1KB5 HSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP ...:: :. ..:::::::::.: :.::.. : : .: .:...:::......: CCDS21 KASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSEYSKIFGSEED 420 430 440 450 460 470 750 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:36:41 2016 done: Sat Nov 5 07:36:42 2016 Total Scan time: 5.010 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]