FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5786, 729 aa 1>>>pF1KB5786 729 - 729 aa - 729 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.1640+/-0.000604; mu= -14.2964+/- 0.037 mean_var=512.3939+/-116.650, 0's: 0 Z-trim(116.0): 2175 B-trim: 1865 in 2/52 Lambda= 0.056659 statistics sampled from 24157 (26901) to 24157 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.315), width: 16 Scan time: 13.190 The best scores are: opt bits E(85289) NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 4762 405.4 4.2e-112 XP_016876787 (OMIM: 602678) PREDICTED: MAP/microtu ( 665) 4225 361.5 6.4e-99 NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 4007 343.7 1.6e-93 XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 4003 343.4 2e-93 NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 3997 342.9 2.8e-93 XP_016876793 (OMIM: 602678) PREDICTED: MAP/microtu ( 598) 3922 336.6 1.7e-91 XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 3897 334.7 8.2e-91 XP_016876799 (OMIM: 602678) PREDICTED: MAP/microtu ( 572) 3726 320.6 1.1e-86 XP_016876800 (OMIM: 602678) PREDICTED: MAP/microtu ( 572) 3726 320.6 1.1e-86 XP_011535071 (OMIM: 602678) PREDICTED: MAP/microtu ( 673) 3470 299.7 2.5e-80 XP_016876783 (OMIM: 602678) PREDICTED: MAP/microtu ( 689) 3470 299.8 2.5e-80 XP_016876785 (OMIM: 602678) PREDICTED: MAP/microtu ( 674) 3466 299.4 3.1e-80 XP_016876784 (OMIM: 602678) PREDICTED: MAP/microtu ( 680) 3460 298.9 4.4e-80 XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 3455 298.5 5.6e-80 XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 3209 278.4 6.8e-74 XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 3201 277.8 1.1e-73 XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 3196 277.4 1.4e-73 XP_016876790 (OMIM: 602678) PREDICTED: MAP/microtu ( 622) 3167 274.9 6.6e-73 XP_016876789 (OMIM: 602678) PREDICTED: MAP/microtu ( 622) 3167 274.9 6.6e-73 XP_016876792 (OMIM: 602678) PREDICTED: MAP/microtu ( 607) 3163 274.6 8.2e-73 XP_016876791 (OMIM: 602678) PREDICTED: MAP/microtu ( 613) 3157 274.1 1.2e-72 XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 3099 269.4 3.4e-71 XP_016876795 (OMIM: 602678) PREDICTED: MAP/microtu ( 596) 2971 258.9 4.3e-68 XP_016876796 (OMIM: 602678) PREDICTED: MAP/microtu ( 596) 2971 258.9 4.3e-68 XP_016876798 (OMIM: 602678) PREDICTED: MAP/microtu ( 587) 2961 258.1 7.5e-68 NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 2805 245.4 6e-64 NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 2791 244.3 1.3e-63 XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 2735 239.7 3.2e-62 XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 2732 239.5 3.8e-62 XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 2730 239.3 4.2e-62 XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 2720 238.5 7.5e-62 XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 2718 238.3 8.4e-62 NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 2709 237.5 1.3e-61 NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752) 2709 237.6 1.4e-61 XP_016876788 (OMIM: 602678) PREDICTED: MAP/microtu ( 664) 2664 233.9 1.7e-60 XP_016876786 (OMIM: 602678) PREDICTED: MAP/microtu ( 673) 2659 233.4 2.2e-60 NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 2574 226.6 3e-58 NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 2574 226.6 3.1e-58 XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 2569 226.2 4e-58 NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 2569 226.2 4.1e-58 XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 2465 217.7 1.5e-55 NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 2453 216.6 2.7e-55 XP_016876797 (OMIM: 602678) PREDICTED: MAP/microtu ( 591) 2369 209.7 2.8e-53 XP_016876794 (OMIM: 602678) PREDICTED: MAP/microtu ( 597) 2361 209.0 4.4e-53 XP_006723370 (OMIM: 606495) PREDICTED: MAP/microtu ( 685) 2351 208.3 8.5e-53 NP_001122393 (OMIM: 602678) MAP/microtubule affini ( 659) 2314 205.2 6.8e-52 XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 2277 202.3 6.1e-51 NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 2272 201.8 7.7e-51 NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 2265 201.3 1.2e-50 XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 2204 196.3 3.9e-49 >>NP_002367 (OMIM: 602678) MAP/microtubule affinity-regu (729 aa) initn: 4762 init1: 4762 opt: 4762 Z-score: 2133.6 bits: 405.4 E(85289): 4.2e-112 Smith-Waterman score: 4762; 100.0% identity (100.0% similar) in 729 aa overlap (1-729:1-729) 10 20 30 40 50 60 pF1KB5 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 STNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 STNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 ANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA 670 680 690 700 710 720 pF1KB5 SKIANELKL ::::::::: NP_002 SKIANELKL >>XP_016876787 (OMIM: 602678) PREDICTED: MAP/microtubule (665 aa) initn: 4321 init1: 4225 opt: 4225 Z-score: 1896.9 bits: 361.5 E(85289): 6.4e-99 Smith-Waterman score: 4225; 100.0% identity (100.0% similar) in 648 aa overlap (82-729:18-665) 60 70 80 90 100 110 pF1KB5 HIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILN :::::::::::::::::::::::::::::: XP_016 MSTRTPLPTVNERDTENVAIKIIDKTQLNPTSLQKLFREVRIMKILN 10 20 30 40 120 130 140 150 160 170 pF1KB5 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQ 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB5 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB5 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 170 180 190 200 210 220 300 310 320 330 340 350 pF1KB5 PIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSK 230 240 250 260 270 280 360 370 380 390 400 410 pF1KB5 MKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSS 290 300 310 320 330 340 420 430 440 450 460 470 pF1KB5 SQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPM 350 360 370 380 390 400 480 490 500 510 520 530 pF1KB5 LGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTI 410 420 430 440 450 460 540 550 560 570 580 590 pF1KB5 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEAT 470 480 490 500 510 520 600 610 620 630 640 650 pF1KB5 PLSQTRSRGSTNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSQTRSRGSTNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDM 530 540 550 560 570 580 660 670 680 690 700 710 pF1KB5 MREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISG 590 600 610 620 630 640 720 pF1KB5 TSIAFKNIASKIANELKL :::::::::::::::::: XP_016 TSIAFKNIASKIANELKL 650 660 >>NP_001122390 (OMIM: 602678) MAP/microtubule affinity-r (753 aa) initn: 4748 init1: 3995 opt: 4007 Z-score: 1799.9 bits: 343.7 E(85289): 1.6e-93 Smith-Waterman score: 4704; 96.8% identity (96.8% similar) in 753 aa overlap (1-729:1-753) 10 20 30 40 50 60 pF1KB5 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 550 560 570 580 590 600 610 620 630 pF1KB5 STNLFSKLTSKLTR------------------------SRNVSAEQKDENKEAKPRSLRF :::::::::::::: :::::::::::::::::::::: NP_001 STNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRF 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB5 TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL 670 680 690 700 710 720 700 710 720 pF1KB5 PRLSLNGVRFKRISGTSIAFKNIASKIANELKL ::::::::::::::::::::::::::::::::: NP_001 PRLSLNGVRFKRISGTSIAFKNIASKIANELKL 730 740 750 >>XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtubule (738 aa) initn: 3995 init1: 3995 opt: 4003 Z-score: 1798.2 bits: 343.4 E(85289): 2e-93 Smith-Waterman score: 4734; 98.8% identity (98.8% similar) in 738 aa overlap (1-729:1-738) 10 20 30 40 50 60 pF1KB5 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 STNLFSKLTSKLTR---------SRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDM :::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_005 STNLFSKLTSKLTRRNMSFRFIKSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDM 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB5 MREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISG 670 680 690 700 710 720 720 pF1KB5 TSIAFKNIASKIANELKL :::::::::::::::::: XP_005 TSIAFKNIASKIANELKL 730 >>NP_001122391 (OMIM: 602678) MAP/microtubule affinity-r (744 aa) initn: 4748 init1: 3995 opt: 3997 Z-score: 1795.5 bits: 342.9 E(85289): 2.8e-93 Smith-Waterman score: 4722; 98.0% identity (98.0% similar) in 744 aa overlap (1-729:1-744) 10 20 30 40 50 60 pF1KB5 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 550 560 570 580 590 600 610 620 630 640 pF1KB5 STNLFSKLTSKLTR---------------SRNVSAEQKDENKEAKPRSLRFTWSMKTTSS :::::::::::::: ::::::::::::::::::::::::::::::: NP_001 STNLFSKLTSKLTRRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRFTWSMKTTSS 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB5 MDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVR 670 680 690 700 710 720 710 720 pF1KB5 FKRISGTSIAFKNIASKIANELKL :::::::::::::::::::::::: NP_001 FKRISGTSIAFKNIASKIANELKL 730 740 >>XP_016876793 (OMIM: 602678) PREDICTED: MAP/microtubule (598 aa) initn: 3922 init1: 3922 opt: 3922 Z-score: 1763.6 bits: 336.6 E(85289): 1.7e-91 Smith-Waterman score: 3922; 100.0% identity (100.0% similar) in 598 aa overlap (132-729:1-598) 110 120 130 140 150 160 pF1KB5 REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ :::::::::::::::::::::::::::::: XP_016 MEYASGGEVFDYLVAHGRMKEKEARSKFRQ 10 20 30 170 180 190 200 210 220 pF1KB5 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAP 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB5 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB5 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYS 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB5 QEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSP 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB5 HHKVQRSVSSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHKVQRSVSSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVG 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB5 GKGIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSV 340 350 360 370 380 390 530 540 550 560 570 580 pF1KB5 IQNGKENSTIPDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQNGKENSTIPDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPP 400 410 420 430 440 450 590 600 610 620 630 640 pF1KB5 ASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASPSLSHEATPLSQTRSRGSTNLFSKLTSKLTRSRNVSAEQKDENKEAKPRSLRFTWSMK 460 470 480 490 500 510 650 660 670 680 690 700 pF1KB5 TTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSL 520 530 540 550 560 570 710 720 pF1KB5 NGVRFKRISGTSIAFKNIASKIANELKL :::::::::::::::::::::::::::: XP_016 NGVRFKRISGTSIAFKNIASKIANELKL 580 590 >>XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtubule (739 aa) initn: 4638 init1: 3885 opt: 3897 Z-score: 1751.4 bits: 334.7 E(85289): 8.2e-91 Smith-Waterman score: 4594; 96.7% identity (96.7% similar) in 736 aa overlap (18-729:4-739) 10 20 30 40 50 60 pF1KB5 MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK ::::::::::::::::::::::::::::::::::::::::::: XP_006 MWEHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLK 10 20 30 40 70 80 90 100 110 120 pF1KB5 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITAT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSD 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNK 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB5 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVAS 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB5 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 THSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRG 530 540 550 560 570 580 610 620 630 pF1KB5 STNLFSKLTSKLTR------------------------SRNVSAEQKDENKEAKPRSLRF :::::::::::::: :::::::::::::::::::::: XP_006 STNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENKEAKPRSLRF 590 600 610 620 630 640 640 650 660 670 680 690 pF1KB5 TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKL 650 660 670 680 690 700 700 710 720 pF1KB5 PRLSLNGVRFKRISGTSIAFKNIASKIANELKL ::::::::::::::::::::::::::::::::: XP_006 PRLSLNGVRFKRISGTSIAFKNIASKIANELKL 710 720 730 >>XP_016876799 (OMIM: 602678) PREDICTED: MAP/microtubule (572 aa) initn: 3726 init1: 3726 opt: 3726 Z-score: 1677.2 bits: 320.6 E(85289): 1.1e-86 Smith-Waterman score: 3726; 99.8% identity (100.0% similar) in 569 aa overlap (161-729:4-572) 140 150 160 170 180 190 pF1KB5 IMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADM .::::::::::::::::::::::::::::: XP_016 MQVEIVSAVQYCHQKRIVHRDLKAENLLLDADM 10 20 30 200 210 220 230 240 250 pF1KB5 NIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB5 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB5 HEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB5 LDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVV 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB5 AYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSS 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB5 TVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATP 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB5 DRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTS 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB5 KLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRE 460 470 480 490 500 510 680 690 700 710 720 pF1KB5 RFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 520 530 540 550 560 570 >>XP_016876800 (OMIM: 602678) PREDICTED: MAP/microtubule (572 aa) initn: 3726 init1: 3726 opt: 3726 Z-score: 1677.2 bits: 320.6 E(85289): 1.1e-86 Smith-Waterman score: 3726; 99.8% identity (100.0% similar) in 569 aa overlap (161-729:4-572) 140 150 160 170 180 190 pF1KB5 IMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADM .::::::::::::::::::::::::::::: XP_016 MQVEIVSAVQYCHQKRIVHRDLKAENLLLDADM 10 20 30 200 210 220 230 240 250 pF1KB5 NIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB5 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB5 HEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSE 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB5 LDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVV 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB5 AYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSS 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB5 TVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATP 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB5 DRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEATPLSQTRSRGSTNLFSKLTS 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB5 KLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTRSRNVSAEQKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRE 460 470 480 490 500 510 680 690 700 710 720 pF1KB5 RFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 520 530 540 550 560 570 >>XP_011535071 (OMIM: 602678) PREDICTED: MAP/microtubule (673 aa) initn: 4211 init1: 3458 opt: 3470 Z-score: 1563.3 bits: 299.7 E(85289): 2.5e-80 Smith-Waterman score: 4167; 96.4% identity (96.4% similar) in 672 aa overlap (82-729:2-673) 60 70 80 90 100 110 pF1KB5 HIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILN :::::::::::::::::::::::::::::: XP_011 MVAIKIIDKTQLNPTSLQKLFREVRIMKILN 10 20 30 120 130 140 150 160 170 pF1KB5 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQ 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 PIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSK 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 MKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKYDEITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSS 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 SQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPM 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB5 LGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTI 400 410 420 430 440 450 540 550 560 570 580 590 pF1KB5 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTFHGQPRERRTATYNGPPASPSLSHEAT 460 470 480 490 500 510 600 610 620 pF1KB5 PLSQTRSRGSTNLFSKLTSKLTR------------------------SRNVSAEQKDENK ::::::::::::::::::::::: ::::::::::::: XP_011 PLSQTRSRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAEQKDENK 520 530 540 550 560 570 630 640 650 660 670 680 pF1KB5 EAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLV 580 590 600 610 620 630 690 700 710 720 pF1KB5 QWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL :::::::::::::::::::::::::::::::::::::::::: XP_011 QWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 640 650 660 670 729 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:21:51 2016 done: Sat Nov 5 16:21:53 2016 Total Scan time: 13.190 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]