FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5789, 829 aa 1>>>pF1KB5789 829 - 829 aa - 829 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7720+/-0.00084; mu= 14.1463+/- 0.051 mean_var=107.4561+/-21.059, 0's: 0 Z-trim(110.2): 189 B-trim: 62 in 1/51 Lambda= 0.123725 statistics sampled from 11232 (11425) to 11232 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.351), width: 16 Scan time: 4.460 The best scores are: opt bits E(32554) CCDS10823.1 CDH16 gene_id:1014|Hs108|chr16 ( 829) 5583 1007.6 0 CCDS58471.1 CDH16 gene_id:1014|Hs108|chr16 ( 790) 4313 780.9 0 CCDS56002.1 CDH16 gene_id:1014|Hs108|chr16 ( 807) 4293 777.4 0 CCDS58472.1 CDH16 gene_id:1014|Hs108|chr16 ( 732) 4148 751.5 1.2e-216 CCDS6260.1 CDH17 gene_id:1015|Hs108|chr8 ( 832) 1290 241.3 5e-63 CCDS9586.1 CDH24 gene_id:64403|Hs108|chr14 ( 781) 613 120.5 1.1e-26 CCDS11993.1 CDH7 gene_id:1005|Hs108|chr18 ( 785) 599 118.0 6.4e-26 CCDS3890.1 CDH12 gene_id:1010|Hs108|chr5 ( 794) 573 113.4 1.6e-24 CCDS3892.1 CDH10 gene_id:1008|Hs108|chr5 ( 788) 569 112.6 2.6e-24 CCDS3894.1 CDH6 gene_id:1004|Hs108|chr5 ( 790) 564 111.7 4.9e-24 CCDS82259.1 CDH7 gene_id:1005|Hs108|chr18 ( 630) 562 111.3 5.2e-24 CCDS2775.1 CELSR3 gene_id:1951|Hs108|chr3 (3312) 570 113.2 7.7e-24 CCDS3889.1 CDH18 gene_id:1016|Hs108|chr5 ( 790) 549 109.1 3.1e-23 CCDS11977.1 CDH20 gene_id:28316|Hs108|chr18 ( 801) 545 108.4 5.2e-23 CCDS3893.1 CDH9 gene_id:1007|Hs108|chr5 ( 789) 542 107.8 7.4e-23 CCDS10802.1 CDH8 gene_id:1006|Hs108|chr16 ( 799) 539 107.3 1.1e-22 CCDS9585.1 CDH24 gene_id:64403|Hs108|chr14 ( 819) 533 106.2 2.3e-22 CCDS10804.1 CDH5 gene_id:1003|Hs108|chr16 ( 784) 516 103.2 1.8e-21 CCDS54835.1 CDH18 gene_id:1016|Hs108|chr5 ( 574) 501 100.4 9.1e-21 CCDS75229.1 CDH18 gene_id:1016|Hs108|chr5 ( 575) 501 100.4 9.1e-21 CCDS11897.1 DSG4 gene_id:147409|Hs108|chr18 (1040) 479 96.6 2.3e-19 CCDS45845.1 DSG4 gene_id:147409|Hs108|chr18 (1059) 479 96.6 2.3e-19 CCDS10869.1 CDH1 gene_id:999|Hs108|chr16 ( 882) 461 93.4 1.8e-18 CCDS75342.1 PCDHGB6 gene_id:56100|Hs108|chr5 ( 820) 460 93.2 2e-18 CCDS54929.1 PCDHGB6 gene_id:56100|Hs108|chr5 ( 930) 460 93.2 2.2e-18 CCDS54923.1 PCDHGB1 gene_id:56104|Hs108|chr5 ( 927) 457 92.7 3.1e-18 CCDS75330.1 PCDHGB1 gene_id:56104|Hs108|chr5 ( 810) 448 91.0 8.5e-18 CCDS64269.1 PCDHA2 gene_id:56146|Hs108|chr5 ( 808) 438 89.3 2.9e-17 CCDS54914.1 PCDHA2 gene_id:56146|Hs108|chr5 ( 948) 438 89.3 3.4e-17 CCDS75348.1 PCDHGC3 gene_id:5098|Hs108|chr5 ( 863) 433 88.4 5.8e-17 CCDS4261.1 PCDHGC3 gene_id:5098|Hs108|chr5 ( 934) 433 88.4 6.2e-17 CCDS75332.1 PCDHGB2 gene_id:56103|Hs108|chr5 ( 811) 430 87.8 7.9e-17 CCDS54924.1 PCDHGB2 gene_id:56103|Hs108|chr5 ( 931) 430 87.9 8.9e-17 CCDS75349.1 PCDHGC4 gene_id:56098|Hs108|chr5 ( 871) 420 86.1 2.9e-16 CCDS4262.1 PCDHGC4 gene_id:56098|Hs108|chr5 ( 938) 420 86.1 3.1e-16 CCDS75331.1 PCDHGA4 gene_id:56111|Hs108|chr5 ( 851) 419 85.9 3.2e-16 CCDS58979.2 PCDHGA4 gene_id:56111|Hs108|chr5 ( 962) 419 85.9 3.6e-16 CCDS59325.1 CDH19 gene_id:28513|Hs108|chr18 ( 490) 414 84.9 3.8e-16 CCDS75346.1 PCDHGA12 gene_id:26025|Hs108|chr5 ( 820) 416 85.3 4.5e-16 CCDS4260.1 PCDHGA12 gene_id:26025|Hs108|chr5 ( 932) 416 85.4 5e-16 CCDS4243.1 PCDHB1 gene_id:29930|Hs108|chr5 ( 818) 415 85.2 5.1e-16 CCDS11994.1 CDH19 gene_id:28513|Hs108|chr18 ( 772) 414 85.0 5.5e-16 CCDS75341.1 PCDHGA9 gene_id:56107|Hs108|chr5 ( 828) 407 83.7 1.4e-15 CCDS58981.1 PCDHGA9 gene_id:56107|Hs108|chr5 ( 932) 407 83.8 1.5e-15 CCDS54922.1 PCDHGA1 gene_id:56114|Hs108|chr5 ( 931) 401 82.7 3.2e-15 CCDS11898.1 DSG3 gene_id:1830|Hs108|chr18 ( 999) 401 82.7 3.4e-15 CCDS75329.1 PCDHGA3 gene_id:56112|Hs108|chr5 ( 829) 397 81.9 4.8e-15 CCDS4242.1 PCDHAC2 gene_id:56134|Hs108|chr5 (1007) 398 82.2 5e-15 CCDS47290.1 PCDHGA3 gene_id:56112|Hs108|chr5 ( 932) 397 82.0 5.3e-15 CCDS47289.1 PCDHGA2 gene_id:56113|Hs108|chr5 ( 932) 393 81.3 8.7e-15 >>CCDS10823.1 CDH16 gene_id:1014|Hs108|chr16 (829 aa) initn: 5583 init1: 5583 opt: 5583 Z-score: 5386.4 bits: 1007.6 E(32554): 0 Smith-Waterman score: 5583; 100.0% identity (100.0% similar) in 829 aa overlap (1-829:1-829) 10 20 30 40 50 60 pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM 730 740 750 760 770 780 790 800 810 820 pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV 790 800 810 820 >>CCDS58471.1 CDH16 gene_id:1014|Hs108|chr16 (790 aa) initn: 4297 init1: 4297 opt: 4313 Z-score: 4161.6 bits: 780.9 E(32554): 0 Smith-Waterman score: 5228; 95.3% identity (95.3% similar) in 829 aa overlap (1-829:1-790) 10 20 30 40 50 60 pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP :::::::::::::::::::::::::::::::::::::::::: CCDS58 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTD------------------ 610 620 630 640 670 680 690 700 710 720 pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT ::::::::::::::::::::::::::::::::::::::: CCDS58 ---------------------HGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT 650 660 670 680 730 740 750 760 770 780 pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM 690 700 710 720 730 740 790 800 810 820 pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV 750 760 770 780 790 >>CCDS56002.1 CDH16 gene_id:1014|Hs108|chr16 (807 aa) initn: 5419 init1: 4289 opt: 4293 Z-score: 4142.2 bits: 777.4 E(32554): 0 Smith-Waterman score: 5379; 97.3% identity (97.3% similar) in 829 aa overlap (1-829:1-807) 10 20 30 40 50 60 pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP ::::::::::::::::::::::::::::::::::::::::: CCDS56 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDT------------------- 610 620 630 640 670 680 690 700 710 720 pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ---ALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT 650 660 670 680 690 730 740 750 760 770 780 pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM 700 710 720 730 740 750 790 800 810 820 pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV 760 770 780 790 800 >>CCDS58472.1 CDH16 gene_id:1014|Hs108|chr16 (732 aa) initn: 4142 init1: 4142 opt: 4148 Z-score: 4002.9 bits: 751.5 E(32554): 1.2e-216 Smith-Waterman score: 4732; 88.3% identity (88.3% similar) in 829 aa overlap (1-829:1-732) 10 20 30 40 50 60 pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF :: CCDS58 DQ---------------------------------------------------------- 190 200 210 220 230 240 pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS ::::::::::::::::::::: CCDS58 ---------------------------------------ASGHQATATVEVSIIESTWVS 130 140 250 260 270 280 290 300 pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA 150 160 170 180 190 200 310 320 330 340 350 360 pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA 210 220 230 240 250 260 370 380 390 400 410 420 pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM 270 280 290 300 310 320 430 440 450 460 470 480 pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE 330 340 350 360 370 380 490 500 510 520 530 540 pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG 390 400 410 420 430 440 550 560 570 580 590 600 pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL 450 460 470 480 490 500 610 620 630 640 650 660 pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP 510 520 530 540 550 560 670 680 690 700 710 720 pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT 570 580 590 600 610 620 730 740 750 760 770 780 pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM 630 640 650 660 670 680 790 800 810 820 pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV 690 700 710 720 730 >>CCDS6260.1 CDH17 gene_id:1015|Hs108|chr8 (832 aa) initn: 810 init1: 376 opt: 1290 Z-score: 1245.0 bits: 241.3 E(32554): 5e-63 Smith-Waterman score: 1290; 30.5% identity (63.0% similar) in 776 aa overlap (65-826:66-828) 40 50 60 70 80 90 pF1KB5 GNFPLYLTKLPLPREGAEGQIVLSGDSGKATEGPFAMDPDSGFLLVTRALDREEQAEYQL :.. :... . :.: .:::::: .. ..: CCDS62 FSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIERE-GLLYYNRALDRETRSTHNL 40 50 60 70 80 90 100 110 120 130 140 150 pF1KB5 QVTLEMQDGHVLWGPQPVLVHVKDENDQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRD ::. .: .. :: :. ..::: ::. : : :. :.. . ...::: :::...:.: : CCDS62 QVAALDANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLD 100 110 120 130 140 150 160 170 180 190 200 210 pF1KB5 EPGTANSDLRFHILSQAPAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQLLVQVK .:.: :..: ..:. : : . .::.. . ::..:. .:: :. : . .:.:...:: CCDS62 DPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVK 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB5 DMGDQA-SGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHL- ::: :. .. . :..:.. . :. : . .:....:: .: ...::.:. ..: : CCDS62 DMGGQSENSFSDTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLV 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB5 --ESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMDEN :. : :: .. ::..:::. :::: . :.. . :.. .:. . :::.:: : : : CCDS62 DKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDIN 280 290 300 310 320 330 340 350 360 370 380 390 pF1KB5 DNVPICPPRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNSHVVYQLLSPEPEDGVEGRA :: : :: . . : :. . :.:.: : .. :: . :... :. ..: CCDS62 DNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDG-L 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB5 FQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFI : .. .: . :. :. :. :..... . :.. : :.. : ::::. : : CCDS62 FLIQTYAGMLQLAKQSLKK-QDTPQYNLTIEVSDKD--FKTLCFVQINVIDINDQIPIFE 400 410 420 430 440 450 460 470 480 490 500 pF1KB5 TSQIGPISLPEDVEPGTLVAMLTAIDADLEP---AFRLMDFAIERGDTEGTFGLDWEP-- :. : ..: ::.. :. . . : ::: :: . ... . : .::.:: .:.: .: CCDS62 KSDYGNLTLAEDTNIGSTILTIQATDAD-EPFTGSSKIL-YHIIKGDSEGRLGVDTDPHT 460 470 480 490 500 510 520 530 540 550 560 pF1KB5 DSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLV-GPGPGPGATATVTVLVERVMPPPKL ..:.: .. : :..:.: ..: ... :: : . .. : :..: : :.. CCDS62 NTGYVIIK--KPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQF 510 520 530 540 550 560 570 580 590 600 610 620 pF1KB5 DQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSLVNDSEGWLCIEKFSGEVHTAQSLQ .:. ..:.: .. :. . .. .:: . . .:: .:..::: :.. .::. .. :. CCDS62 SQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLD 570 580 590 600 610 620 630 640 650 660 670 680 pF1KB5 GAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGL . :. : : : : .. ::. . . . .. . : . ..: : . : CCDS62 -REAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGS 630 640 650 660 670 680 690 700 710 720 730 740 pF1KB5 IVSGPSKDPDLASGHGP-YSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPREHIIP .. . : : .:: ..:.:: . ..: ::... .::.:: :. : ::... CCDS62 LIF-EATDDDQHLFRGPHFTFSLGSG-SLQNDWEVSKINGTHARLSTRHTEFEEREYVVL 690 700 710 720 730 740 750 760 770 780 790 800 pF1KB5 VVVSHNAQM-WQLLVRVIV--CRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIF . .. ... . .: . : : : :::.:.: .:.. :.:: :::::. ::..:::. CCDS62 IRINDGGRPPLEGIVSLPVTFCSC-VEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGII 750 760 770 780 790 800 810 820 pF1KB5 LILIFTHWTMSRKKDPDQPADSVPLKATV : ..: . .. :: . :.. .: CCDS62 LAVVFIRIKKDKGKDNVESAQASEVKPLRS 810 820 830 >>CCDS9586.1 CDH24 gene_id:64403|Hs108|chr14 (781 aa) initn: 260 init1: 136 opt: 613 Z-score: 592.4 bits: 120.5 E(32554): 1.1e-26 Smith-Waterman score: 613; 30.9% identity (56.2% similar) in 596 aa overlap (252-814:63-628) 230 240 250 260 270 280 pF1KB5 GHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFE :: . ..: . : ..: : .. : CCDS95 EHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVF 40 50 60 70 80 90 290 300 310 320 330 pF1KB5 V--NAEGNLYVTRELDREAQAEYLLQVRAQN-SHGEDYAAPLELHVLVMDENDNVPICPP : .: ::..::. :::: .:.:.: ..: . . .. : :. . :.: ::: :: : CCDS95 VIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPL 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB5 RDPTVSIPELSPPGTEVTRLSAEDADAPGSPNS-HVVYQLLSPEPEDGVEGRAFQVDPTS ...::.: :: : ...:.::: :. :: ..:: .: ::. :.::: . CCDS95 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVL-----DGLP--FFSVDPQT 160 170 180 190 200 400 410 420 430 440 450 pF1KB5 GSVTLGVLPL-RAGQNILLLVL-AMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIG : : .. . : :. .:.:. : :..: ::.:.. : :...:.::. :.: : . CCDS95 GVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQS-LY 210 220 230 240 250 260 460 470 480 490 500 510 pF1KB5 PISLPEDVEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGL--DWEPDSGHVRLR .:. : . :::::. : : : :: :: ..: :. .:.. : . .: . .: CCDS95 QFSVVETAGPGTLVGRLRAQDPDLGDN-ALMAYSILDGEGSEAFSISTDLQGRDGLLTVR 270 280 290 300 310 320 520 530 540 550 560 pF1KB5 LCKNLSYEAAPSHEVVVVVQSVAKLVGPGP---GP-GATATVTVLVERVMPPPKLDQESY : :..:. :. : ... :. :. :: .:.: : :. . :: . : .: CCDS95 --KPLDFESQRSYSFRV--EATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAY 330 340 350 360 370 570 580 590 600 610 620 pF1KB5 EASVPISAPAGSFLLTIQPSD---PISRTLRFSLVNDSEGWLC--IEKFSGEVHTAQSL- . .:: . :... :. .: : : .:.:.. :. : :. : .::: : CCDS95 HLTVPENKAPGTLVGQISAADLDSPAS-PIRYSILPHSDPERCFSIQPEEGTIHTAAPLD 380 390 400 410 420 430 630 640 650 660 670 680 pF1KB5 QGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFL-KAPPAPALTLAPVPSQYLCTPRQDH . :. . ::: : . : .. . ..:. : . :: :. : . ..: CCDS95 REARAWHNLTVL--ATELDSSAQASRVQVAIQTLDENDNAPQLA-EPYDT-FVCDSAAPG 440 450 460 470 480 490 690 700 710 720 730 pF1KB5 GLI--VSGPSKDPDLASGHGPYSFTLGP--NPTVQRDWRLQTLNGSHAYLTLALHWVEPR :: . . ..: :.: .. ::: : ::: : : .:: : : : . . :: CCDS95 QLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQ-DNR----DGS-ASLLLPSRPAPPR 500 510 520 530 540 740 750 760 770 780 790 pF1KB5 E--HIIPVVV---SHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGMP-TKLSAVGILVG . ...:. . .. : : : ::::. .:. . : ..:::.:. .: CCDS95 HAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVA------SCWPEAHLSAAGLSTG 550 560 570 580 590 600 800 810 820 pF1KB5 TLVAI----GIFLILIFTHWTMSRKKDPDQPADSVPLKATV .:.:: : .: :. .. :.: CCDS95 ALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDI 610 620 630 640 650 660 >>CCDS11993.1 CDH7 gene_id:1005|Hs108|chr18 (785 aa) initn: 434 init1: 124 opt: 599 Z-score: 578.8 bits: 118.0 E(32554): 6.4e-26 Smith-Waterman score: 599; 26.9% identity (58.4% similar) in 580 aa overlap (259-816:73-637) 230 240 250 260 270 280 pF1KB5 VEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAE--G ..: . :...: : .. . . . : : CCDS11 SRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTG 50 60 70 80 90 100 290 300 310 320 330 340 pF1KB5 NLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPL-ELHVLVMDENDNVPICPPRDPTVSI ....:..:::: :: : :...: . . . : :. . ..: ::: : :... CCDS11 DIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGV 110 120 130 140 150 160 350 360 370 380 390 400 pF1KB5 PELSPPGTEVTRLSAEDADAPGSPNS-HVVYQLLSPEPEDGVEGRAFQVDPTSGSV--TL ::.:: :: :....: ::: : :: .:::..:. .: :.:.: .: . .: CCDS11 PEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPY-------FSVEPKTGVIKTAL 170 180 190 200 210 410 420 430 440 450 460 pF1KB5 GVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPED . .: .. ::.. : :..: .::.:.: : :..::.::. :.: . ..::. CCDS11 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSY-QYNVPES 220 230 240 250 260 270 470 480 490 500 510 520 pF1KB5 VEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEA . ...:: . : :::. : :.. : :: : : .. . .. . . . :.:..:: CCDS11 LPVASVVARIKAADADI-GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 280 290 300 310 320 330 530 540 550 560 570 pF1KB5 APSHEVVVVVQSVAKLVGP---GPGP-GATATVTVLVERVMPPPKLDQESYEASVPISAP :. .. .... : . : . :: . :.:: ..:: : :: ... : : .. CCDS11 KTSY--TLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQ 340 350 360 370 380 390 580 590 600 610 620 630 pF1KB5 AGSFLLTIQPSDPISRT--LRFSL--VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTV .:... :. :: : . .:.:. .: : .. :. :: . ::.::. . . ... CCDS11 VGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLD-RETNAIHNI 400 410 420 430 440 450 640 650 660 670 680 690 pF1KB5 LVEAQDTDEPRLSASAPLVIHFLKAPP-APALTLAPVPSQYLCTPRQDHGLIVSGPSKDP : :.....: . . ..: .: :: ... . .: : .: . . : CCDS11 TVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETT--VCENAQPGQVIQKISAVDK 460 470 480 490 500 700 710 720 730 740 pF1KB5 DLASGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPRE---HIIPVVV--SH : :. . :.: . : .... :. . . : . . . .: . .:. . : CCDS11 DEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSG 510 520 530 540 550 560 750 760 770 780 790 800 pF1KB5 NAQMWQL-LVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFLILIFTH . .. . . . :: :...: . .. .:. ::. : :.. :. . .:.::. CCDS11 SPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLST-GALIAILACVLTLLVLILLI 570 580 590 600 610 620 810 820 pF1KB5 WTMSR-KKDPDQPADSVPLKATV :: : ::.: CCDS11 VTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVT 630 640 650 660 670 680 >>CCDS3890.1 CDH12 gene_id:1010|Hs108|chr5 (794 aa) initn: 259 init1: 113 opt: 573 Z-score: 553.7 bits: 113.4 E(32554): 1.6e-24 Smith-Waterman score: 573; 24.9% identity (57.0% similar) in 586 aa overlap (255-817:72-644) 230 240 250 260 270 pF1KB5 ATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWS---G-GDVHYHLESHPPGP- :......: . : : :.: : . : CCDS38 LPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTV 50 60 70 80 90 100 280 290 300 310 320 330 pF1KB5 FEVN-AEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPL-ELHVLVMDENDNVPICP : .. . :.... : :::: . : :...: . . . : :. . :.: ::: : CCDS38 FTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFL 110 120 130 140 150 160 340 350 360 370 380 390 pF1KB5 PRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNS-HVVYQLLSPEPEDGVEGRAFQVDPT ....::.:: :. : ...: ::: : :: .:::..:. .: :..:: CCDS38 DGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQPY-------FSIDPK 170 180 190 200 210 400 410 420 430 440 450 pF1KB5 SGSV--TLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQI .: . .: . .. .. .:. : :..: ::...: :....::.::. :.: : : CCDS38 TGVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKS-I 220 230 240 250 260 270 460 470 480 490 500 510 pF1KB5 GPISLPEDVEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRL ...::. :. .. . :.: :. .. .. : :: . : . . :. . ..: CCDS38 FHLKVPESSPIGSAIGRIRAVDPDFGQNAEI-EYNIVPGDGGNLFDIVTDEDTQEGVIKL 280 290 300 310 320 330 520 530 540 550 560 570 pF1KB5 CKNLSYEAAPSHEVVVVVQSVA---KLVGPGPGPGATATVTVLVERVMPPPKLDQESYEA : :..:. .. : .... .. . :: :::: . : : :: ... : CCDS38 KKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFKD-TATVKISVLDVDEPPVFSKPLYTM 340 350 360 370 380 390 580 590 600 610 620 pF1KB5 SVPISAPAGSFL--LTIQPSDPISRTLRFSL--VNDSEGWLCIEKFSGEVHTAQSLQGAQ : ..:.:... .: : : : ..:. . .:..... :. : . : . :. . CCDS38 EVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB5 PGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGLIVS .. :. . :. ...: :.... ..:. : . : .: . .: . .: CCDS38 TAQ-YNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETA-VCENAKPGQIIQI 460 470 480 490 500 690 700 710 720 730 740 pF1KB5 GPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPRE---HIIPV . : ::. . .:: :.:. ... .. .. . .. : . . :. ...:: CCDS38 VSAADRDLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPV 510 520 530 540 550 560 750 760 770 780 790 800 pF1KB5 VV---SHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFL :. :. .: . . ::::. .: . . .:. ::. : :.. :. : :.: CCDS38 VIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLST-GALIAILLCIVILL 570 580 590 600 610 620 810 820 pF1KB5 ILIFTHWTMSRKKDPDQPADSVPLKATV .. . .. :.: : CCDS38 AIVVLYVALRRQKKKDTLMTSKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPKVIEENK 630 640 650 660 670 680 >>CCDS3892.1 CDH10 gene_id:1008|Hs108|chr5 (788 aa) initn: 268 init1: 133 opt: 569 Z-score: 549.9 bits: 112.6 E(32554): 2.6e-24 Smith-Waterman score: 569; 27.7% identity (56.0% similar) in 582 aa overlap (266-816:87-642) 240 250 260 270 280 290 pF1KB5 STWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAE--GNLYVTRE :...: : . : . . : :....::. CCDS38 MWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRR 60 70 80 90 100 110 300 310 320 330 340 350 pF1KB5 LDREAQAEYLLQVRAQNSHGEDYAAPL-ELHVLVMDENDNVPICPPRDPTVSIPELSPPG .::: .: : :...: : . . : :. . . : ::: : : . :.:.::.: : CCDS38 IDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVG 120 130 140 150 160 170 360 370 380 390 400 410 pF1KB5 TEVTRLSAEDADAPGSPNS-HVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQ : :....: ::: :. :: .:.:..:. .: :.:.: .: . . :: . CCDS38 TSVVQVTATDADDPSYGNSARVIYSILQGQPY-------FSVEPETGIIRTA-LPNMNRE 180 190 200 210 220 420 430 440 450 460 pF1KB5 N---ILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTL : ... : :..: ::.:.: :....::.::. :.: . : . . :. :: CCDS38 NREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIH-LRVLESSPVGTA 230 240 250 260 270 280 470 480 490 500 510 520 pF1KB5 VAMLTAIDADL----EPAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAP .. . : ::: : .:..: :: : . : :. . . . : :.::. CCDS38 IGSVKATDADTGKNAEVEYRIID-----GDGTDMFDIVTEKDTQEGIITVKKPLDYESRR 290 300 310 320 330 340 530 540 550 560 570 580 pF1KB5 SHEVVVVVQSV---AKLVGPGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGS . . : .... .. :: .: : . .: : :: ... :: : . .:. CCDS38 LYTLKVEAENTHVDPRFYYLGPFKDTTI-VKISIEDVDEPPVFSRSSYLFEVHEDIEVGT 350 360 370 380 390 400 590 600 610 620 630 pF1KB5 FLLTIQPSDP--ISRTLRFSLV--NDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVE .. :.. :: :: .:::: .: . . :.. .: ..:.. :. . .. ... : CCDS38 IIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLD-RELSQWHNLTVI 410 420 430 440 450 460 640 650 660 670 680 690 pF1KB5 AQDTDEPRLSASAPLVIHFLKAPP-APALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLA : . ..:. .. . . ...: . :: .: . ..: . :: . . : : CCDS38 AAEINNPKETTRVAVFVRILDVNDNAPQ--FAVFYDTFVCENARPGQLIQTISAVDKDDP 470 480 490 500 510 700 710 720 730 740 750 pF1KB5 SGHGPYSFTLG---PNPTVQ--RDWRLQTLNGSHAYLTLALHWVEPREHIIPVVVSHNAQ : . :.:. :: ::: .: . :. .... : : ...:::.: : CCDS38 LGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGF---NRH--EISTYLLPVVISDNDY 520 530 540 550 560 570 760 770 780 790 800 pF1KB5 MWQ-----LLVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFLILI-- : : .:: : :. .:. . .. .:. ::. : :.. :. : :.:... CCDS38 PIQSSTGTLTIRV--CACDSQGNMQSCSAEALLLPAGLST-GALIAILLCIIILLVIVVL 580 590 600 610 620 630 810 820 pF1KB5 FTHWTMSRKKDPDQPADSVPLKATV :. .:::.: CCDS38 FAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDI 640 650 660 670 680 690 >>CCDS3894.1 CDH6 gene_id:1004|Hs108|chr5 (790 aa) initn: 224 init1: 123 opt: 564 Z-score: 545.0 bits: 111.7 E(32554): 4.9e-24 Smith-Waterman score: 564; 27.8% identity (56.3% similar) in 579 aa overlap (266-816:86-644) 240 250 260 270 280 290 pF1KB5 STWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAE--GNLYVTRE :...: : . : . . : :.. .:.. CCDS38 MWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKR 60 70 80 90 100 110 300 310 320 330 340 350 pF1KB5 LDREAQAEYLLQVRAQNSH-GEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPG :::: . :.:...: : . :. :. . . : ::: :: . :...::.: : CCDS38 LDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVG 120 130 140 150 160 170 360 370 380 390 400 410 pF1KB5 TEVTRLSAEDADAPGSPNS-HVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPL-RAG : :....: ::: : :: .:::..:. .: :.:. .: . ..: . : . CCDS38 TFVVQVTATDADDPTYGNSAKVVYSILQGQPY-------FSVESETGIIKTALLNMDREN 180 190 200 210 220 420 430 440 450 460 pF1KB5 QNILLLVL-AMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLV .. .:. : :..: ::.:.: :....::.::. :.: : .. ::. ::: . CCDS38 REQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTY-QFKTPESSPPGTPI 230 240 250 260 270 280 470 480 490 500 510 520 pF1KB5 AMLTAIDADL-EPAFRLMDFAIERGDTEGTFGL--DWEPDSGHVRLRLCKNLSYEAAPSH . . : :::. : : ....: :. : . : : . : . .. : :..: . CCDS38 GRIKASDADVGENAE--IEYSITDGEGLDMFDVITDQETQEGIITVK--KLLDFEKKKVY 290 300 310 320 330 340 530 540 550 560 570 580 pF1KB5 EVVVVVQSVAKLVGP-----GPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGS .. :.. : : :: .::: ..:: : :: ... .: .. .: .. CCDS38 --TLKVEASNPYVEPRFLYLGPFKD-SATVRIVVEDVDEPPVFSKLAYILQIREDAQINT 350 360 370 380 390 400 590 600 610 620 630 pF1KB5 FLLTIQPSDP-ISRT-LRFSLV--NDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVE . .. .:: .:. ...:. .: . . :.. .: . :.. : . ... : CCDS38 TIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSK-LLDRETLLWHNITVI 410 420 430 440 450 640 650 660 670 680 690 pF1KB5 AQDTDEPRLSASAPLVIHFLKAPP-APALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLA : . ..:. :. .:: :. : . :: .: ..: . :: . . : : CCDS38 ATEINNPKQSSRVPLYIKVLDVNDNAPE--FAEFYETFVCEKAKADQLIQTLHAVDKDDP 460 470 480 490 500 510 700 710 720 730 740 pF1KB5 -SGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPRE---HIIPVVVSHN--- ::: .::.:.:. . .. .: . . : . . . .: ...:::.: : CCDS38 YSGH-QFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYP 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB5 AQMWQLLVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFLILI--FTH .: : : :: :. .:. . .. :: ::. : ::. :. : :.:. . :. CCDS38 VQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLST-GALVAILLCIVILLVTVVLFAA 580 590 600 610 620 630 810 820 pF1KB5 WTMSRKKDPDQPADSVPLKATV .:::.: CCDS38 LRRQRKKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIVPE 640 650 660 670 680 690 829 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:22:33 2016 done: Sat Nov 5 16:22:34 2016 Total Scan time: 4.460 Total Display time: 0.260 Function used was FASTA [36.3.4 Apr, 2011]