Result of FASTA (omim) for
pF1KB5789
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5789, 829 aa
1>>>pF1KB5789 829 - 829 aa - 829 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6245+/-0.000354; mu= 15.0326+/- 0.022
mean_var=109.2589+/-22.239, 0's: 0 Z-trim(117.6): 400 B-trim: 1425 in 2/53
Lambda= 0.122700
statistics sampled from 29251 (29662) to 29251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.348), width: 16
Scan time: 14.120
The best scores are: opt bits E(85289)
NP_004053 (OMIM: 603118) cadherin-16 isoform 1 pre ( 829) 5583 999.5 0
XP_005255827 (OMIM: 603118) PREDICTED: cadherin-16 ( 651) 4362 783.3 0
NP_001191674 (OMIM: 603118) cadherin-16 isoform 3 ( 790) 4313 774.7 0
NP_001191673 (OMIM: 603118) cadherin-16 isoform 2 ( 807) 4293 771.1 0
NP_001191675 (OMIM: 603118) cadherin-16 isoform 4 ( 732) 4148 745.4 2.1e-214
XP_011521109 (OMIM: 603118) PREDICTED: cadherin-16 ( 766) 3048 550.7 8.8e-156
NP_001138135 (OMIM: 603017) cadherin-17 precursor ( 832) 1290 239.6 4.5e-62
NP_004054 (OMIM: 603017) cadherin-17 precursor [Ho ( 832) 1290 239.6 4.5e-62
XP_011515092 (OMIM: 603017) PREDICTED: cadherin-17 ( 752) 1033 194.0 2.1e-48
NP_387450 (OMIM: 605806) cadherin-7 isoform 1 prep ( 785) 599 117.2 2.9e-25
NP_004352 (OMIM: 605806) cadherin-7 isoform 1 prep ( 785) 599 117.2 2.9e-25
XP_016881012 (OMIM: 605806) PREDICTED: cadherin-7 ( 785) 599 117.2 2.9e-25
NP_001304153 (OMIM: 604555) cadherin-10 isoform 3 ( 786) 580 113.9 2.9e-24
XP_016864404 (OMIM: 604555) PREDICTED: cadherin-10 ( 786) 580 113.9 2.9e-24
XP_016864409 (OMIM: 600562) PREDICTED: cadherin-12 ( 794) 573 112.6 7e-24
XP_016864410 (OMIM: 600562) PREDICTED: cadherin-12 ( 794) 573 112.6 7e-24
NP_001304156 (OMIM: 600562) cadherin-12 isoform 1 ( 794) 573 112.6 7e-24
NP_004052 (OMIM: 600562) cadherin-12 isoform 1 pre ( 794) 573 112.6 7e-24
XP_011512229 (OMIM: 600562) PREDICTED: cadherin-12 ( 794) 573 112.6 7e-24
XP_011512225 (OMIM: 604555) PREDICTED: cadherin-10 ( 788) 569 111.9 1.1e-23
NP_006718 (OMIM: 604555) cadherin-10 isoform 1 pre ( 788) 569 111.9 1.1e-23
XP_011512223 (OMIM: 603007) PREDICTED: cadherin-6 ( 790) 564 111.0 2.1e-23
NP_004923 (OMIM: 603007) cadherin-6 preproprotein ( 790) 564 111.0 2.1e-23
XP_016864399 (OMIM: 603007) PREDICTED: cadherin-6 ( 790) 564 111.0 2.1e-23
NP_001304143 (OMIM: 605806) cadherin-7 isoform 2 p ( 630) 562 110.6 2.2e-23
NP_001398 (OMIM: 604264) cadherin EGF LAG seven-pa (3312) 570 112.5 3.2e-23
XP_016864416 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
NP_004925 (OMIM: 603019) cadherin-18 isoform 1 pre ( 790) 549 108.4 1.3e-22
XP_016864418 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864421 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864414 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864413 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_005248285 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864417 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864415 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
NP_001278885 (OMIM: 603019) cadherin-18 isoform 1 ( 790) 549 108.4 1.3e-22
XP_006714498 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864419 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
XP_016864420 (OMIM: 603019) PREDICTED: cadherin-18 ( 790) 549 108.4 1.3e-22
NP_114097 (OMIM: 605807) cadherin-20 preproprotein ( 801) 545 107.7 2.2e-22
XP_011512230 (OMIM: 603019) PREDICTED: cadherin-18 ( 724) 543 107.3 2.6e-22
NP_057363 (OMIM: 609974) cadherin-9 preproprotein ( 789) 542 107.1 3.1e-22
XP_016864400 (OMIM: 603007) PREDICTED: cadherin-6 ( 663) 539 106.6 3.9e-22
XP_005255817 (OMIM: 603008) PREDICTED: cadherin-8 ( 711) 539 106.6 4.2e-22
NP_001787 (OMIM: 603008) cadherin-8 preproprotein ( 799) 539 106.6 4.6e-22
NP_001786 (OMIM: 601120) cadherin-5 preproprotein ( 784) 516 102.5 7.6e-21
XP_011521103 (OMIM: 601120) PREDICTED: cadherin-5 ( 793) 505 100.6 2.9e-20
XP_016864429 (OMIM: 603019) PREDICTED: cadherin-18 ( 574) 501 99.8 3.7e-20
XP_016864430 (OMIM: 603019) PREDICTED: cadherin-18 ( 574) 501 99.8 3.7e-20
XP_016864428 (OMIM: 603019) PREDICTED: cadherin-18 ( 574) 501 99.8 3.7e-20
>>NP_004053 (OMIM: 603118) cadherin-16 isoform 1 precurs (829 aa)
initn: 5583 init1: 5583 opt: 5583 Z-score: 5342.5 bits: 999.5 E(85289): 0
Smith-Waterman score: 5583; 100.0% identity (100.0% similar) in 829 aa overlap (1-829:1-829)
10 20 30 40 50 60
pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
730 740 750 760 770 780
790 800 810 820
pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
790 800 810 820
>>XP_005255827 (OMIM: 603118) PREDICTED: cadherin-16 iso (651 aa)
initn: 4362 init1: 4362 opt: 4362 Z-score: 4175.9 bits: 783.3 E(85289): 0
Smith-Waterman score: 4362; 100.0% identity (100.0% similar) in 651 aa overlap (179-829:1-651)
150 160 170 180 190 200
pF1KB5 EASDRDEPGTANSDLRFHILSQAPAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQ
::::::::::::::::::::::::::::::
XP_005 MFQLEPRLGALALSPKGSTSLDHALERTYQ
10 20 30
210 220 230 240 250 260
pF1KB5 LLVQVKDMGDQASGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVQVKDMGDQASGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDV
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB5 HYHLESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYHLESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMD
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB5 ENDNVPICPPRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNSHVVYQLLSPEPEDGVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENDNVPICPPRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNSHVVYQLLSPEPEDGVEG
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB5 RAFQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAFQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPE
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB5 FITSQIGPISLPEDVEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGLDWEPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FITSQIGPISLPEDVEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGLDWEPDSG
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB5 HVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVGPGPGPGATATVTVLVERVMPPPKLDQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVGPGPGPGATATVTVLVERVMPPPKLDQES
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB5 YEASVPISAPAGSFLLTIQPSDPISRTLRFSLVNDSEGWLCIEKFSGEVHTAQSLQGAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEASVPISAPAGSFLLTIQPSDPISRTLRFSLVNDSEGWLCIEKFSGEVHTAQSLQGAQP
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB5 GDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGLIVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGLIVSG
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB5 PSKDPDLASGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPREHIIPVVVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSKDPDLASGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPREHIIPVVVSH
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB5 NAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFLILIFTHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFLILIFTHW
580 590 600 610 620 630
810 820
pF1KB5 TMSRKKDPDQPADSVPLKATV
:::::::::::::::::::::
XP_005 TMSRKKDPDQPADSVPLKATV
640 650
>>NP_001191674 (OMIM: 603118) cadherin-16 isoform 3 prec (790 aa)
initn: 4297 init1: 4297 opt: 4313 Z-score: 4127.8 bits: 774.7 E(85289): 0
Smith-Waterman score: 5228; 95.3% identity (95.3% similar) in 829 aa overlap (1-829:1-790)
10 20 30 40 50 60
pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
::::::::::::::::::::::::::::::::::::::::::
NP_001 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTD------------------
610 620 630 640
670 680 690 700 710 720
pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
:::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------HGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
650 660 670 680
730 740 750 760 770 780
pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
690 700 710 720 730 740
790 800 810 820
pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
750 760 770 780 790
>>NP_001191673 (OMIM: 603118) cadherin-16 isoform 2 prec (807 aa)
initn: 5419 init1: 4289 opt: 4293 Z-score: 4108.5 bits: 771.1 E(85289): 0
Smith-Waterman score: 5379; 97.3% identity (97.3% similar) in 829 aa overlap (1-829:1-807)
10 20 30 40 50 60
pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
:::::::::::::::::::::::::::::::::::::::::
NP_001 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDT-------------------
610 620 630 640
670 680 690 700 710 720
pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---ALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
650 660 670 680 690
730 740 750 760 770 780
pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
700 710 720 730 740 750
790 800 810 820
pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
760 770 780 790 800
>>NP_001191675 (OMIM: 603118) cadherin-16 isoform 4 prec (732 aa)
initn: 4142 init1: 4142 opt: 4148 Z-score: 3970.4 bits: 745.4 E(85289): 2.1e-214
Smith-Waterman score: 4732; 88.3% identity (88.3% similar) in 829 aa overlap (1-829:1-732)
10 20 30 40 50 60
pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
::
NP_001 DQ----------------------------------------------------------
190 200 210 220 230 240
pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
:::::::::::::::::::::
NP_001 ---------------------------------------ASGHQATATVEVSIIESTWVS
130 140
250 260 270 280 290 300
pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
330 340 350 360 370 380
490 500 510 520 530 540
pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
390 400 410 420 430 440
550 560 570 580 590 600
pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
450 460 470 480 490 500
610 620 630 640 650 660
pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
510 520 530 540 550 560
670 680 690 700 710 720
pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
570 580 590 600 610 620
730 740 750 760 770 780
pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
630 640 650 660 670 680
790 800 810 820
pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
690 700 710 720 730
>>XP_011521109 (OMIM: 603118) PREDICTED: cadherin-16 iso (766 aa)
initn: 3099 init1: 3048 opt: 3048 Z-score: 2917.8 bits: 550.7 E(85289): 8.8e-156
Smith-Waterman score: 5017; 92.4% identity (92.4% similar) in 829 aa overlap (1-829:1-766)
10 20 30 40 50 60
pF1KB5 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVPAWLWLLCVSVPQALPKAQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSPPGTEVTRLSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDADAPGSPNSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLE
:::::::::::::::::::::::::::::::::
XP_011 DLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQ---------------------------
430 440 450
490 500 510 520 530 540
pF1KB5 PAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLVG
::::::::::::::::::::::::
XP_011 ------------------------------------NLSYEAAPSHEVVVVVQSVAKLVG
460 470
550 560 570 580 590 600
pF1KB5 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPGPGATATVTVLVERVMPPPKLDQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSL
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB5 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAP
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB5 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPALTLAPVPSQYLCTPRQDHGLIVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQT
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB5 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNGSHAYLTLALHWVEPREHIIPVVVSHNAQMWQLLVRVIVCRCNVEGQCMRKVGRMKGM
660 670 680 690 700 710
790 800 810 820
pF1KB5 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTKLSAVGILVGTLVAIGIFLILIFTHWTMSRKKDPDQPADSVPLKATV
720 730 740 750 760
>>NP_001138135 (OMIM: 603017) cadherin-17 precursor [Hom (832 aa)
initn: 810 init1: 376 opt: 1290 Z-score: 1235.4 bits: 239.6 E(85289): 4.5e-62
Smith-Waterman score: 1290; 30.5% identity (63.0% similar) in 776 aa overlap (65-826:66-828)
40 50 60 70 80 90
pF1KB5 GNFPLYLTKLPLPREGAEGQIVLSGDSGKATEGPFAMDPDSGFLLVTRALDREEQAEYQL
:.. :... . :.: .:::::: .. ..:
NP_001 FSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIERE-GLLYYNRALDRETRSTHNL
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB5 QVTLEMQDGHVLWGPQPVLVHVKDENDQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRD
::. .: .. :: :. ..::: ::. : : :. :.. . ...::: :::...:.: :
NP_001 QVAALDANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLD
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB5 EPGTANSDLRFHILSQAPAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQLLVQVK
.:.: :..: ..:. : : . .::.. . ::..:. .:: :. : . .:.:...::
NP_001 DPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVK
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB5 DMGDQA-SGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHL-
::: :. .. . :..:.. . :. : . .:....:: .: ...::.:. ..: :
NP_001 DMGGQSENSFSDTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLV
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB5 --ESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMDEN
:. : :: .. ::..:::. :::: . :.. . :.. .:. . :::.:: : : :
NP_001 DKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDIN
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB5 DNVPICPPRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNSHVVYQLLSPEPEDGVEGRA
:: : :: . . : :. . :.:.: : .. :: . :... :. ..:
NP_001 DNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDG-L
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB5 FQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFI
: .. .: . :. :. :. :..... . :.. : :.. : ::::. : :
NP_001 FLIQTYAGMLQLAKQSLKK-QDTPQYNLTIEVSDKD--FKTLCFVQINVIDINDQIPIFE
400 410 420 430 440 450
460 470 480 490 500
pF1KB5 TSQIGPISLPEDVEPGTLVAMLTAIDADLEP---AFRLMDFAIERGDTEGTFGLDWEP--
:. : ..: ::.. :. . . : ::: :: . ... . : .::.:: .:.: .:
NP_001 KSDYGNLTLAEDTNIGSTILTIQATDAD-EPFTGSSKIL-YHIIKGDSEGRLGVDTDPHT
460 470 480 490 500
510 520 530 540 550 560
pF1KB5 DSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLV-GPGPGPGATATVTVLVERVMPPPKL
..:.: .. : :..:.: ..: ... :: : . .. : :..: : :..
NP_001 NTGYVIIK--KPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQF
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB5 DQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSLVNDSEGWLCIEKFSGEVHTAQSLQ
.:. ..:.: .. :. . .. .:: . . .:: .:..::: :.. .::. .. :.
NP_001 SQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLD
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB5 GAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGL
. :. : : : : .. ::. . . . .. . : . ..: : . :
NP_001 -REAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGS
630 640 650 660 670 680
690 700 710 720 730 740
pF1KB5 IVSGPSKDPDLASGHGP-YSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPREHIIP
.. . : : .:: ..:.:: . ..: ::... .::.:: :. : ::...
NP_001 LIF-EATDDDQHLFRGPHFTFSLGSG-SLQNDWEVSKINGTHARLSTRHTEFEEREYVVL
690 700 710 720 730 740
750 760 770 780 790 800
pF1KB5 VVVSHNAQM-WQLLVRVIV--CRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIF
. .. ... . .: . : : : :::.:.: .:.. :.:: :::::. ::..:::.
NP_001 IRINDGGRPPLEGIVSLPVTFCSC-VEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGII
750 760 770 780 790 800
810 820
pF1KB5 LILIFTHWTMSRKKDPDQPADSVPLKATV
: ..: . .. :: . :.. .:
NP_001 LAVVFIRIKKDKGKDNVESAQASEVKPLRS
810 820 830
>>NP_004054 (OMIM: 603017) cadherin-17 precursor [Homo s (832 aa)
initn: 810 init1: 376 opt: 1290 Z-score: 1235.4 bits: 239.6 E(85289): 4.5e-62
Smith-Waterman score: 1290; 30.5% identity (63.0% similar) in 776 aa overlap (65-826:66-828)
40 50 60 70 80 90
pF1KB5 GNFPLYLTKLPLPREGAEGQIVLSGDSGKATEGPFAMDPDSGFLLVTRALDREEQAEYQL
:.. :... . :.: .:::::: .. ..:
NP_004 FSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIERE-GLLYYNRALDRETRSTHNL
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB5 QVTLEMQDGHVLWGPQPVLVHVKDENDQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRD
::. .: .. :: :. ..::: ::. : : :. :.. . ...::: :::...:.: :
NP_004 QVAALDANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLD
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB5 EPGTANSDLRFHILSQAPAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQLLVQVK
.:.: :..: ..:. : : . .::.. . ::..:. .:: :. : . .:.:...::
NP_004 DPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVK
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB5 DMGDQA-SGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHL-
::: :. .. . :..:.. . :. : . .:....:: .: ...::.:. ..: :
NP_004 DMGGQSENSFSDTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLV
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB5 --ESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMDEN
:. : :: .. ::..:::. :::: . :.. . :.. .:. . :::.:: : : :
NP_004 DKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDIN
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB5 DNVPICPPRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNSHVVYQLLSPEPEDGVEGRA
:: : :: . . : :. . :.:.: : .. :: . :... :. ..:
NP_004 DNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDG-L
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB5 FQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFI
: .. .: . :. :. :. :..... . :.. : :.. : ::::. : :
NP_004 FLIQTYAGMLQLAKQSLKK-QDTPQYNLTIEVSDKD--FKTLCFVQINVIDINDQIPIFE
400 410 420 430 440 450
460 470 480 490 500
pF1KB5 TSQIGPISLPEDVEPGTLVAMLTAIDADLEP---AFRLMDFAIERGDTEGTFGLDWEP--
:. : ..: ::.. :. . . : ::: :: . ... . : .::.:: .:.: .:
NP_004 KSDYGNLTLAEDTNIGSTILTIQATDAD-EPFTGSSKIL-YHIIKGDSEGRLGVDTDPHT
460 470 480 490 500
510 520 530 540 550 560
pF1KB5 DSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLV-GPGPGPGATATVTVLVERVMPPPKL
..:.: .. : :..:.: ..: ... :: : . .. : :..: : :..
NP_004 NTGYVIIK--KPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQF
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB5 DQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSLVNDSEGWLCIEKFSGEVHTAQSLQ
.:. ..:.: .. :. . .. .:: . . .:: .:..::: :.. .::. .. :.
NP_004 SQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLD
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB5 GAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGL
. :. : : : : .. ::. . . . .. . : . ..: : . :
NP_004 -REAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGS
630 640 650 660 670 680
690 700 710 720 730 740
pF1KB5 IVSGPSKDPDLASGHGP-YSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPREHIIP
.. . : : .:: ..:.:: . ..: ::... .::.:: :. : ::...
NP_004 LIF-EATDDDQHLFRGPHFTFSLGSG-SLQNDWEVSKINGTHARLSTRHTEFEEREYVVL
690 700 710 720 730 740
750 760 770 780 790 800
pF1KB5 VVVSHNAQM-WQLLVRVIV--CRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIF
. .. ... . .: . : : : :::.:.: .:.. :.:: :::::. ::..:::.
NP_004 IRINDGGRPPLEGIVSLPVTFCSC-VEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGII
750 760 770 780 790 800
810 820
pF1KB5 LILIFTHWTMSRKKDPDQPADSVPLKATV
: ..: . .. :: . :.. .:
NP_004 LAVVFIRIKKDKGKDNVESAQASEVKPLRS
810 820 830
>>XP_011515092 (OMIM: 603017) PREDICTED: cadherin-17 iso (752 aa)
initn: 812 init1: 376 opt: 1033 Z-score: 990.1 bits: 194.0 E(85289): 2.1e-48
Smith-Waterman score: 1045; 28.8% identity (57.8% similar) in 775 aa overlap (65-826:66-748)
40 50 60 70 80 90
pF1KB5 GNFPLYLTKLPLPREGAEGQIVLSGDSGKATEGPFAMDPDSGFLLVTRALDREEQAEYQL
:.. :... . :.: .:::::: .. ..:
XP_011 FSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFVIERE-GLLYYNRALDRETRSTHNL
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB5 QVTLEMQDGHVLWGPQPVLVHVKDENDQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRD
::. .: .. :: :. ..::: ::. : : :. :.. . ...::: :::...:.: :
XP_011 QVAALDANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLD
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB5 EPGTANSDLRFHILSQAPAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQLLVQVK
.:.: :..: ..:. : : . .::.. . ::..:. .:: :. : . .:.:...::
XP_011 DPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVK
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB5 DMGDQA-SGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHL-
::: :. .. . :..:.. . :. : . .:....:: .: ...::.:. ..: :
XP_011 DMGGQSENSFSDTTSVDIIVTENIWKAPKPVEMVENSTDPHPIKITQVRWNDPGAQYSLV
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB5 --ESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMDEN
:. : :: .. ::..:::. :::: . :.. . :.. .:. . :::.:: : : :
XP_011 DKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDIN
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB5 DNVPICPPRDPTVSIPELSPPGTEVTRLSAEDADAPGSPNSHVVYQLLSPEPEDGVEGRA
:: : :: . . : :. . :.:.: : .. :: . :... :. ..:
XP_011 DNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDG-L
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB5 FQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFI
: .. .: . :. :. :. :..... . :.. : :.. : ::::. : :
XP_011 FLIQTYAGMLQLAKQSLKK-QDTPQYNLTIEVSDKD--FKTLCFVQINVIDINDQIPIFE
400 410 420 430 440 450
460 470 480 490 500
pF1KB5 TSQIGPISLPEDVEPGTLVAMLTAIDADLEP---AFRLMDFAIERGDTEGTFGLDWEP--
:. : ..: ::.. :. . . : ::: :: . ... . : .::.:: .:.: .:
XP_011 KSDYGNLTLAEDTNIGSTILTIQATDAD-EPFTGSSKIL-YHIIKGDSEGRLGVDTDPHT
460 470 480 490 500
510 520 530 540 550 560
pF1KB5 DSGHVRLRLCKNLSYEAAPSHEVVVVVQSVAKLV-GPGPGPGATATVTVLVERVMPPPKL
..:.: .. : :..:.: ..: ... :: : . .. : :..: : :..
XP_011 NTGYVIIK--KPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQF
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB5 DQESYEASVPISAPAGSFLLTIQPSDPISRTLRFSLVNDSEGWLCIEKFSGEVHTAQSLQ
.:. ..:.: .. :. . .. .:: . . .:: .:..::: :.. .::. ..
XP_011 SQHVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSV----
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB5 GAQPGDTYTVLVEAQDTDEPRLSASAPLVIHFLKAPPAPALTLAPVPSQYLCTPRQDHGL
:::
XP_011 -------------------------APL--------------------------------
690 700 710 720 730 740
pF1KB5 IVSGPSKDPDLASGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPREHIIPV
: .: .:: : . : :.:: :. : ::... .
XP_011 ---------DREAG-SPY-----------RVQVVATEVGTHARLSTRHTEFEEREYVVLI
630 640 650 660
750 760 770 780 790 800
pF1KB5 VVSHNAQM-WQLLVRVIV--CRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFL
.. ... . .: . : : : :::.:.: .:.. :.:: :::::. ::..:::.:
XP_011 RINDGGRPPLEGIVSLPVTFCSC-VEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGIIL
670 680 690 700 710 720
810 820
pF1KB5 ILIFTHWTMSRKKDPDQPADSVPLKATV
..: . .. :: . :.. .:
XP_011 AVVFIRIKKDKGKDNVESAQASEVKPLRS
730 740 750
>>NP_387450 (OMIM: 605806) cadherin-7 isoform 1 prepropr (785 aa)
initn: 434 init1: 124 opt: 599 Z-score: 574.7 bits: 117.2 E(85289): 2.9e-25
Smith-Waterman score: 599; 26.9% identity (58.4% similar) in 580 aa overlap (259-816:73-637)
230 240 250 260 270 280
pF1KB5 VEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAE--G
..: . :...: : .. . . . : :
NP_387 SRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTG
50 60 70 80 90 100
290 300 310 320 330 340
pF1KB5 NLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPL-ELHVLVMDENDNVPICPPRDPTVSI
....:..:::: :: : :...: . . . : :. . ..: ::: : :...
NP_387 DIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGV
110 120 130 140 150 160
350 360 370 380 390 400
pF1KB5 PELSPPGTEVTRLSAEDADAPGSPNS-HVVYQLLSPEPEDGVEGRAFQVDPTSGSV--TL
::.:: :: :....: ::: : :: .:::..:. .: :.:.: .: . .:
NP_387 PEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPY-------FSVEPKTGVIKTAL
170 180 190 200 210
410 420 430 440 450 460
pF1KB5 GVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPED
. .: .. ::.. : :..: .::.:.: : :..::.::. :.: . ..::.
NP_387 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSY-QYNVPES
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB5 VEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGLDWEPDSGHVRLRLCKNLSYEA
. ...:: . : :::. : :.. : :: : : .. . .. . . . :.:..::
NP_387 LPVASVVARIKAADADI-GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA
280 290 300 310 320 330
530 540 550 560 570
pF1KB5 APSHEVVVVVQSVAKLVGP---GPGP-GATATVTVLVERVMPPPKLDQESYEASVPISAP
:. .. .... : . : . :: . :.:: ..:: : :: ... : : ..
NP_387 KTSY--TLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQ
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB5 AGSFLLTIQPSDPISRT--LRFSL--VNDSEGWLCIEKFSGEVHTAQSLQGAQPGDTYTV
.:... :. :: : . .:.:. .: : .. :. :: . ::.::. . . ...
NP_387 VGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLD-RETNAIHNI
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB5 LVEAQDTDEPRLSASAPLVIHFLKAPP-APALTLAPVPSQYLCTPRQDHGLIVSGPSKDP
: :.....: . . ..: .: :: ... . .: : .: . . :
NP_387 TVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETT--VCENAQPGQVIQKISAVDK
460 470 480 490 500
700 710 720 730 740
pF1KB5 DLASGHGPYSFTLGPNPTVQRDWRLQTLNGSHAYLTLALHWVEPRE---HIIPVVV--SH
: :. . :.: . : .... :. . . : . . . .: . .:. . :
NP_387 DEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSG
510 520 530 540 550 560
750 760 770 780 790 800
pF1KB5 NAQMWQL-LVRVIVCRCNVEGQCMRKVGRMKGMPTKLSAVGILVGTLVAIGIFLILIFTH
. .. . . . :: :...: . .. .:. ::. : :.. :. . .:.::.
NP_387 SPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLST-GALIAILACVLTLLVLILLI
570 580 590 600 610 620
810 820
pF1KB5 WTMSR-KKDPDQPADSVPLKATV
:: : ::.:
NP_387 VTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVT
630 640 650 660 670 680
829 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:22:34 2016 done: Sat Nov 5 16:22:36 2016
Total Scan time: 14.120 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]