Result of FASTA (omim) for
pF1KB5791
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5791, 830 aa
1>>>pF1KB5791 830 - 830 aa - 830 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3254+/-0.000629; mu= 11.5117+/- 0.039
mean_var=254.6928+/-49.764, 0's: 0 Z-trim(114.9): 354 B-trim: 147 in 2/50
Lambda= 0.080365
statistics sampled from 24634 (25050) to 24634 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.294), width: 16
Scan time: 12.850
The best scores are: opt bits E(85289)
XP_005245493 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 6027 713.7 8.2e-205
XP_005245492 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 6027 713.7 8.2e-205
NP_002996 (OMIM: 147050,173610) P-selectin precurs ( 830) 6027 713.7 8.2e-205
XP_005245496 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 5574 661.2 5.2e-189
XP_005245495 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 5574 661.2 5.2e-189
XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768) 3673 440.8 1.1e-122
NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610) 1875 232.2 5.6e-60
NP_000646 (OMIM: 153240) L-selectin precursor [Hom ( 385) 1229 157.0 1.5e-37
NP_001868 (OMIM: 120650,240500,610927,614699) comp (1033) 841 112.6 9.4e-24
XP_011507508 (OMIM: 120650,240500,610927,614699) P ( 969) 760 103.2 6.1e-21
NP_001006659 (OMIM: 120650,240500,610927,614699) c (1092) 760 103.2 6.5e-21
XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 661 92.2 2.8e-17
XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 661 92.4 3.7e-17
XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 661 92.4 3.7e-17
NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 661 92.4 3.7e-17
XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 661 92.5 3.7e-17
XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 661 92.5 3.7e-17
XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 661 92.5 3.8e-17
NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 661 92.5 3.8e-17
XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 661 92.5 3.8e-17
NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 661 92.5 3.8e-17
NP_783641 (OMIM: 605886) complement component rece ( 569) 540 77.3 2.1e-13
NP_000177 (OMIM: 126700,134370,235400,609814,61069 (1231) 541 77.9 3.1e-13
NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597) 535 76.8 3.2e-13
XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 535 76.8 3.2e-13
XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 535 76.8 3.2e-13
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 523 76.5 2.4e-12
XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 518 75.6 2.8e-12
XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 518 75.7 3e-12
XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 518 75.8 3.5e-12
XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 518 75.9 3.6e-12
NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 518 75.9 3.6e-12
NP_000564 (OMIM: 120620,607486,611162) complement (2039) 513 75.0 3.9e-12
XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 513 75.1 4.4e-12
XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 513 75.1 4.5e-12
NP_000642 (OMIM: 120620,607486,611162) complement (2489) 510 74.7 5.6e-12
NP_000033 (OMIM: 138700) beta-2-glycoprotein 1 pre ( 345) 459 67.6 1.1e-10
NP_443128 (OMIM: 608398) CUB and sushi domain-cont (3487) 442 67.0 1.6e-09
XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 442 67.1 1.6e-09
XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 442 67.1 1.6e-09
NP_001268885 (OMIM: 608398) CUB and sushi domain-c (3631) 442 67.1 1.7e-09
XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 436 66.3 2.6e-09
XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 436 66.4 2.6e-09
XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 436 66.4 2.7e-09
XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 436 66.4 2.7e-09
XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 436 66.4 2.7e-09
XP_016856728 (OMIM: 610278) PREDICTED: platelet en ( 973) 384 59.6 8.1e-08
XP_016856727 (OMIM: 610278) PREDICTED: platelet en ( 973) 384 59.6 8.1e-08
XP_016856726 (OMIM: 610278) PREDICTED: platelet en ( 973) 384 59.6 8.1e-08
XP_011507813 (OMIM: 610278) PREDICTED: platelet en (1002) 384 59.6 8.2e-08
>>XP_005245493 (OMIM: 147050,173610) PREDICTED: P-select (830 aa)
initn: 6027 init1: 6027 opt: 6027 Z-score: 3798.0 bits: 713.7 E(85289): 8.2e-205
Smith-Waterman score: 6027; 99.8% identity (100.0% similar) in 830 aa overlap (1-830:1-830)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRV
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_005 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 SCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
730 740 750 760 770 780
790 800 810 820 830
pF1KB5 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
790 800 810 820 830
>>XP_005245492 (OMIM: 147050,173610) PREDICTED: P-select (830 aa)
initn: 6027 init1: 6027 opt: 6027 Z-score: 3798.0 bits: 713.7 E(85289): 8.2e-205
Smith-Waterman score: 6027; 99.8% identity (100.0% similar) in 830 aa overlap (1-830:1-830)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRV
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_005 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 SCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
730 740 750 760 770 780
790 800 810 820 830
pF1KB5 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
790 800 810 820 830
>>NP_002996 (OMIM: 147050,173610) P-selectin precursor [ (830 aa)
initn: 6027 init1: 6027 opt: 6027 Z-score: 3798.0 bits: 713.7 E(85289): 8.2e-205
Smith-Waterman score: 6027; 99.8% identity (100.0% similar) in 830 aa overlap (1-830:1-830)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRV
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_002 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 SCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
730 740 750 760 770 780
790 800 810 820 830
pF1KB5 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
790 800 810 820 830
>>XP_005245496 (OMIM: 147050,173610) PREDICTED: P-select (790 aa)
initn: 5570 init1: 5570 opt: 5574 Z-score: 3514.4 bits: 661.2 E(85289): 5.2e-189
Smith-Waterman score: 5690; 94.9% identity (95.2% similar) in 830 aa overlap (1-830:1-790)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRV
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_005 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 SCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
::::::::::::::::::::::::::::::::::::::::::
XP_005 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ------------------
730 740 750 760
790 800 810 820 830
pF1KB5 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
::::::::::::::::::::::::::::
XP_005 ----------------------DDGKCPLNPHSHLGTYGVFTNAAFDPSP
770 780 790
>>XP_005245495 (OMIM: 147050,173610) PREDICTED: P-select (790 aa)
initn: 5570 init1: 5570 opt: 5574 Z-score: 3514.4 bits: 661.2 E(85289): 5.2e-189
Smith-Waterman score: 5690; 94.9% identity (95.2% similar) in 830 aa overlap (1-830:1-790)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRV
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_005 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 SCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
::::::::::::::::::::::::::::::::::::::::::
XP_005 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ------------------
730 740 750 760
790 800 810 820 830
pF1KB5 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
::::::::::::::::::::::::::::
XP_005 ----------------------DDGKCPLNPHSHLGTYGVFTNAAFDPSP
770 780 790
>>XP_005245497 (OMIM: 147050,173610) PREDICTED: P-select (768 aa)
initn: 3967 init1: 3617 opt: 3673 Z-score: 2323.4 bits: 440.8 E(85289): 1.1e-122
Smith-Waterman score: 5432; 92.4% identity (92.5% similar) in 830 aa overlap (1-830:1-768)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRV
:::::::::::::::::::::
XP_005 PEVVQCTASGVWTAPAPVCKA---------------------------------------
310 320
370 380 390 400 410 420
pF1KB5 RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
:::::::::::::::::::::::::::::::::::::
XP_005 -----------------------ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF
330 340 350
430 440 450 460 470 480
pF1KB5 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB5 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB5 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHF
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB5 SCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPG
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB5 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB5 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVA
660 670 680 690 700 710
790 800 810 820 830
pF1KB5 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP
720 730 740 750 760
>>NP_000441 (OMIM: 131210,145500) E-selectin precursor [ (610 aa)
initn: 1620 init1: 1206 opt: 1875 Z-score: 1197.8 bits: 232.2 E(85289): 5.6e-60
Smith-Waterman score: 1875; 44.7% identity (70.7% similar) in 552 aa overlap (21-569:4-549)
10 20 30 40 50 60
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYC
::.: ::: : :: .::.:. ::.:.... . ::
NP_000 MIASQFL--SALTLVLLI-KESGAWSYNTSTEAMTYDEASAYC
10 20 30 40
70 80 90 100 110 120
pF1KB5 QNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADN
:.::: :::::::.::.:::..: : ::::::::: :..:.::::.: ::.::.::: .
NP_000 QQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 EPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGN
::::....::::::::: . : ::::.: ::: ::::::.: . ::: .:::.:::.:
NP_000 EPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 YTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPS
:::.: ::: : .:: . .: :: :.: . :::::::::.::.::. : :: ..
NP_000 YTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 KLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVG
..:..:: :. : : ...: . : : . :... .: ...:.:.::::: :.:
NP_000 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG
230 240 250 260 270 280
310 320 330 340 350
pF1KB5 PEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVH-PLTAFAYGSSCKFECQPGYR
. .:::.:: : :.:::: :. .. :..:.. : : : :.. :::.: :. :.
NP_000 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 VRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLR-AFQYDTNCSFRCAE
..: ...: .:.:. .:.:::..: : .: .: :.: :: .:.: ..: : : .
NP_000 LQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQ
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB5 GFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSH-PFGAFRYQSVCSFT
::.:.:. ..: :.: :.:.:..:. . : .. : :.: :.: : :.: :.:.
NP_000 GFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFS
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB5 CNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQ
:.::. : :.. :.: . :.:. : ::.. :. : : . .:.: : . ..:.
NP_000 CEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCS---GEPVFGTVCK
470 480 490 500 510
540 550 560 570 580 590
pF1KB5 FICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGST
: : ::..:.: : .:.:. : :::
NP_000 FACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLW
520 530 540 550 560 570
600 610 620 630 640 650
pF1KB5 CHFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRH
NP_000 LRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL
580 590 600 610
>>NP_000646 (OMIM: 153240) L-selectin precursor [Homo sa (385 aa)
initn: 1668 init1: 1225 opt: 1229 Z-score: 795.1 bits: 157.0 E(85289): 1.5e-37
Smith-Waterman score: 1229; 51.3% identity (74.5% similar) in 310 aa overlap (11-320:21-330)
10 20 30 40 50
pF1KB5 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKA
: :: ...: .: .. : .. .. . :::::: :
NP_000 MGCRRTREGPSKAMIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 YSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKAL
..:. .:..:.. :::::::::: ::.::.:.::. ::::::::: . ::::::.:.:
NP_000 MNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 TNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSK
:.:::::.:.:::::.:.::::::::: . :::::. : : : ::::::::: :::
NP_000 TEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 QGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHC
.:::.: :.::::.: :.:::.:..: .: :: :. :.:.::::::::.:::.: :
NP_000 HGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 TDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSF
..: ...: . : : :.. : : . :: ::. :. : :.: : .:. :.:.:
NP_000 SEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 SCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSC
: :: :.: . . : .::.:. :.:.:.
NP_000 ICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSG
310 320 330 340 350 360
>>NP_001868 (OMIM: 120650,240500,610927,614699) compleme (1033 aa)
initn: 364 init1: 161 opt: 841 Z-score: 547.5 bits: 112.6 E(85289): 9.4e-24
Smith-Waterman score: 863; 28.8% identity (51.0% similar) in 626 aa overlap (179-762:126-715)
150 160 170 180 190 200
pF1KB5 HCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPG-FYGPE----CEYVR--ECG
:: . : . ..:: : : ::
NP_001 VPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB5 ELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQ
: . : . :. .:... . . .. : .:: . : . ..::.:: :. :: : :.
NP_001 ALPMI-HNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEAR
160 170 180 190 200 210
270 280 290 300 310
pF1KB5 CPPL-KIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG---VWTAPAP
: : ..:. :.. . .. . .: :.::. : :: .:. .: .:: :
NP_001 CKSLGRFPN-GKV---KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MP
220 230 240 250 260
320 330 340 350 360 370
pF1KB5 VCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQP------GYRVRGLDMLRC-ID
::. . : : . . :. .::: . :.: .. . : . ::: .:
NP_001 VCEEIFCPS-PPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD
270 280 290 300 310 320
380 390 400 410 420
pF1KB5 S---GHWSAPLPTCE----AISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLR
: : ::.: : :: :..: : . ..: : . . : . :. . : : :: :.
NP_001 SQKTGTWSGPAPRCELSTSAVQC-PHPQILRGRMVSGQKDR-YTYNDTVIFACMFGFTLK
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 GADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLL
:. .::. : : ::::. .:: : ... . : : . ...:: : .
NP_001 GSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMV-RFDPGTSIKYSCNPGYV
390 400 410 420 430 440
490 500 510 520 530
pF1KB5 LVGASVLQCLATGNWNSVPPECQAIPCTP-----LLSPQNGTMTCVQPLGSSSYKSTCQF
::: .:: . : :. :.:.. : : .::. :.: .::
NP_001 LVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQH---QFVRPDVNSS-------
450 460 470 480 490
540 550 560 570 580 590
pF1KB5 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC
: :::.::: .: . : .:. : :: . .:. :. . .: :.:
NP_001 -CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLE-DFPYGTTV
500 510 520 530 540 550
600 610 620 630 640
pF1KB5 HFSCNNG------FKLEGPNNVECTTS----GRWSATPPTCKGIASLPTPGVQCPALTTP
..:: : :.: : ....::.. : ::. : :: : .::: .
NP_001 TYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK----LSLLAVQCSHVHIA
560 570 580 590 600
650 660 670 680 690 700
pF1KB5 GQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELH
. . .. : . .: : : : .:::: :.: . :. .. : :.:. :. :
NP_001 NGYKISGKEAP--YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ--H
610 620 630 640 650 660
710 720 730 740 750 760
pF1KB5 VNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQ--ENGHWSTTVPTCQAGPL
: . . ..: .. : . . : .: :.: : :: ::: : .: :.
NP_001 VRQSL----QELPAG-SRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHC
670 680 690 700 710
770 780 790 800 810 820
pF1KB5 TIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAF
NP_001 HPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC
720 730 740 750 760 770
>--
initn: 321 init1: 144 opt: 376 Z-score: 256.1 bits: 58.7 E(85289): 1.6e-07
Smith-Waterman score: 422; 27.2% identity (56.4% similar) in 257 aa overlap (206-445:721-970)
180 190 200 210 220 230
pF1KB5 ETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHP---LGNFSFNSQCSFHCTD
: :..: .: :: .... :..: .
NP_001 LTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQ
700 710 720 730 740 750
240 250 260 270 280
pF1KB5 GYQVNGPSKLECLAS----GIWTNKPPQCL----AAQCPPLKIPERGNMTCLHSAKAFQH
:. . : .::.: .. : :.. :::: ...:: .. . ... :: :..:
NP_001 GFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHS--AYSH
760 770 780 790 800
290 300 310 320 330 340
pF1KB5 QSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVC--KA-VQCQHLEAPNEGTMDCVHP-
.. .:. :: . : .:..: ....:. .:.: :: . : : : . :
NP_001 NDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP----PPPKTPNGNHTG
810 820 830 840 850 860
350 360 370 380 390
pF1KB5 --LTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMD
.. :. : : . :. :: . : .: : : :: : : :. ..: . . : .
NP_001 GNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSS-PADMDGIQK
870 880 890 900 910 920
400 410 420 430 440 450
pF1KB5 CSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEAR
. .:: . ...: .:.::.:. .:.. ::. : ::..
NP_001 GLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAG
930 940 950 960 970 980
460 470 480 490 500 510
pF1KB5 VNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQN
NP_001 LILLTFLIVITLYVISKHRARNYYTDTSQKEAFHLEAREVYSVDPYNPAS
990 1000 1010 1020 1030
>>XP_011507508 (OMIM: 120650,240500,610927,614699) PREDI (969 aa)
initn: 433 init1: 161 opt: 760 Z-score: 497.0 bits: 103.2 E(85289): 6.1e-21
Smith-Waterman score: 872; 28.3% identity (50.9% similar) in 637 aa overlap (179-772:3-605)
150 160 170 180 190 200
pF1KB5 HCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPG-FYGPE----CEYVR--ECG
:: . : . ..:: : : ::
XP_011 MNGNKSVWCQANNMWGPTRLPTCVSVFPLECP
10 20 30
210 220 230 240 250 260
pF1KB5 ELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQ
: . : . :. .:... . . .. : .:: . : . ..::.:: :. :: : :.
XP_011 ALPMI-HNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEAR
40 50 60 70 80 90
270 280 290 300 310
pF1KB5 CPPL-KIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG---VWTAPAP
: : ..:. :.. . .. . .: :.::. : :: .:. .: .:: :
XP_011 CKSLGRFPN-GKV---KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MP
100 110 120 130 140
320 330 340 350 360 370
pF1KB5 VCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQP------GYRVRGLDMLRC-ID
::. . : : . . :. .::: . :.: .. . : . ::: .:
XP_011 VCEEIFCPS-PPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD
150 160 170 180 190 200
380 390 400 410 420
pF1KB5 S---GHWSAPLPTCE----AISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLR
: : ::.: : :: :..: : . ..: : . . : . :. . : : :: :.
XP_011 SQKTGTWSGPAPRCELSTSAVQC-PHPQILRGRMVSGQKDR-YTYNDTVIFACMFGFTLK
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB5 GADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLL
:. .::. : : ::::. .:: : ... . : : . ...:: : .
XP_011 GSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMV-RFDPGTSIKYSCNPGYV
270 280 290 300 310 320
490 500 510 520 530
pF1KB5 LVGASVLQCLATGNWNSVPPECQAIPCTP-----LLSPQNGTMTCVQPLGSSSYKSTCQF
::: .:: . : :. :.:.. : : .::. :.: .::
XP_011 LVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQH---QFVRPDVNSS-------
330 340 350 360 370
540 550 560 570 580 590
pF1KB5 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC
: :::.::: .: . : .:. : :: . .:. :. . .: :.:
XP_011 -CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLE-DFPYGTTV
380 390 400 410 420
600 610 620 630 640
pF1KB5 HFSCNNG------FKLEGPNNVECTTS----GRWSATPPTCKGIASLPTPGVQCPALTTP
..:: : :.: : ....::.. : ::. : :: : .::: .
XP_011 TYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK----LSLLAVQCSHVHIA
430 440 450 460 470 480
650 660 670 680 690 700
pF1KB5 GQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELH
. . .. : . .: : : : .:::: :.: . :. .. : :.:. :.
XP_011 NGYKISGKEAP--YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK-GCQ---
490 500 510 520 530
710 720 730 740 750 760
pF1KB5 VNKPIAMNCSNLWGN---FSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGP
. : . . :: : : .. : : :: :. . :. .:.:: ..: :.
XP_011 -SPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETC
540 550 560 570 580 590
770 780 790 800 810 820
pF1KB5 LTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAA
....:
XP_011 QHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPP
600 610 620 630 640 650
>--
initn: 321 init1: 144 opt: 376 Z-score: 256.4 bits: 58.6 E(85289): 1.5e-07
Smith-Waterman score: 500; 27.0% identity (57.3% similar) in 300 aa overlap (230-514:621-913)
200 210 220 230 240 250
pF1KB5 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECL--ASGIWTNKPPQC
: ::::..: . : .::: .: : :
XP_011 APRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC
600 610 620 630 640 650
260 270 280 290 300 310
pF1KB5 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTAS----GVWT
. .: : . :. : . :. : . . :. :..:: :.: . .:: .. : :.
XP_011 KVIHCHPPPVIVNGKHTGMM-AENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS
660 670 680 690 700
320 330 340 350 360
pF1KB5 APAPVC----KAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCI
.:.: : ...: . :. . .. .: .:..... .:.::. . : ..::
XP_011 GPSPQCLRSPPVTRCPNPEVKHGYKLNKTH--SAYSHNDIVYVDCNPGFIMNGSRVIRCH
710 720 730 740 750 760
370 380 390 400 410 420
pF1KB5 DSGHWSAPLPTC--EA-ISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGAD
.. : .::: .: :.: : . .:. . .. :. . . : .:..: :
XP_011 TDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHT-GGNIARFSPGMSILYSCDQGYLLVGEA
770 780 790 800 810 820
430 440 450 460 470 480
pF1KB5 IVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVG
.. : . : :. ::: :. ..:.. :. .. . .: ..: .: .. :..: .: :
XP_011 LLLCTHEGTWSQPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEG
830 840 850 860 870 880
490 500 510 520 530 540
pF1KB5 ASVLQCLATGNWNSVPPE--CQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGY
. :: . .:: :: :.. .:.:
XP_011 SPQSQCQSDHQWN--PPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYY
890 900 910 920 930 940
830 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 9 12:18:15 2016 done: Wed Nov 9 12:18:17 2016
Total Scan time: 12.850 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]