FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5801, 371 aa 1>>>pF1KB5801 371 - 371 aa - 371 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2081+/-0.000774; mu= 14.5380+/- 0.047 mean_var=121.1684+/-23.403, 0's: 0 Z-trim(112.1): 15 B-trim: 38 in 1/52 Lambda= 0.116514 statistics sampled from 12895 (12901) to 12895 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.396), width: 16 Scan time: 2.870 The best scores are: opt bits E(32554) CCDS2253.1 CDCA7 gene_id:83879|Hs108|chr2 ( 371) 2548 438.9 3.3e-123 CCDS2252.1 CDCA7 gene_id:83879|Hs108|chr2 ( 450) 2246 388.2 7.3e-108 CCDS47558.1 CDCA7L gene_id:55536|Hs108|chr7 ( 408) 739 134.9 1.2e-31 CCDS47559.1 CDCA7L gene_id:55536|Hs108|chr7 ( 420) 739 134.9 1.3e-31 CCDS5374.1 CDCA7L gene_id:55536|Hs108|chr7 ( 454) 739 134.9 1.3e-31 >>CCDS2253.1 CDCA7 gene_id:83879|Hs108|chr2 (371 aa) initn: 2548 init1: 2548 opt: 2548 Z-score: 2325.4 bits: 438.9 E(32554): 3.3e-123 Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGMNFLEKRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGMNFLEKRAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRARPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 NIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRARPL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 TRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 PVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 LRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYL 310 320 330 340 350 360 370 pF1KB5 KSLKQEFEMQA ::::::::::: CCDS22 KSLKQEFEMQA 370 >>CCDS2252.1 CDCA7 gene_id:83879|Hs108|chr2 (450 aa) initn: 2233 init1: 2233 opt: 2246 Z-score: 2050.0 bits: 388.2 E(32554): 7.3e-108 Smith-Waterman score: 2246; 93.7% identity (97.4% similar) in 349 aa overlap (24-371:102-450) 10 20 30 40 50 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFAN-TRLQ .: .. ..:.:.: .:. ... . ::: CCDS22 ESFCGFSESEVQDVLDHCGFLQKPRPDVTNELAGIFHADSDDESFCGFSESEIQDGMRLQ 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB5 SVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 SVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGM 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB5 NFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 NFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRN 200 210 220 230 240 250 180 190 200 210 220 230 pF1KB5 PERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 PERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSS 260 270 280 290 300 310 240 250 260 270 280 290 pF1KB5 VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGV 320 330 340 350 360 370 300 310 320 330 340 350 pF1KB5 RGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS22 RGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHG 380 390 400 410 420 430 360 370 pF1KB5 FGNVHAYLKSLKQEFEMQA ::::::::::::::::::: CCDS22 FGNVHAYLKSLKQEFEMQA 440 450 >>CCDS47558.1 CDCA7L gene_id:55536|Hs108|chr7 (408 aa) initn: 937 init1: 728 opt: 739 Z-score: 681.5 bits: 134.9 E(32554): 1.2e-31 Smith-Waterman score: 960; 43.5% identity (66.8% similar) in 391 aa overlap (6-367:33-404) 10 20 30 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSS-S ::.. : ... .: .. .. . :. : CCDS47 LATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQVVESDLS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 DDSCDSFASDNFANTRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQ- ::. :..:.. . . ... :.::. : : ::::..::... . .:.. :.: CCDS47 DDGKASLVSEEEEDEEEDKATPR-RSRSR-RSSIGLRVAFQFPTKKLANKPDKNSSSEQL 70 80 90 100 110 120 100 110 120 pF1KB5 ------------------------PSENSVTDSNSDSEDES--GMNFLEKRALNIKQNKA :.:...:..::.::: . . : ::..:::.::: CCDS47 FSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKA 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB5 MLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRR-NPERRARPLTRSRSR :::.:..::.:.: : : : : :... :: : .:: :: : ::: . CCDS47 MLAQLLAELNSMPDFFPVR--TPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKF--- 190 200 210 220 230 190 200 210 220 230 240 pF1KB5 ILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEIT .:. . . . .... :.:::. : : :: : : .::::.:: CCDS47 ---ALENFTVSAAKFAEEFYSFRRRKTIGGKCRE----YRRRHRISS-----FRPVEDIT 240 250 260 270 280 250 260 270 280 290 300 pF1KB5 EEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYG ::.:::: . :.:::.. ::.:::::::::::::: ::: : :::::::::::::::: CCDS47 EEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYG 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB5 EEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQE :.::.:::::.: :::::::::::.::.::::::::.:..:::..:. ::. ::.::..: CCDS47 EDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKE 350 360 370 380 390 400 370 pF1KB5 FEMQA . CCDS47 LVEDN >>CCDS47559.1 CDCA7L gene_id:55536|Hs108|chr7 (420 aa) initn: 937 init1: 728 opt: 739 Z-score: 681.3 bits: 134.9 E(32554): 1.3e-31 Smith-Waterman score: 957; 45.5% identity (67.4% similar) in 365 aa overlap (31-367:71-416) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :. :::. :..:.. . . ... :. CCDS47 EDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPR-RS 50 60 70 80 90 70 80 90 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQ-------------------------PS ::. : : ::::..::... . .:.. :.: CCDS47 RSR-RSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQR 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB5 ENSVTDSNSDSEDES--GMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSD :.:...:..::.::: . . : ::..:::.::::::.:..::.:.: : : : : CCDS47 EDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVR--TPTSA 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB5 SQSRRPRRRTFPGVASRR-NPERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRK :... :: : .:: :: : ::: . .:. . . . .... :.:: CCDS47 SRKKTVRRAFSEGQITRRMNPTRSARPPEKF------ALENFTVSAAKFAEEFYSFRRRK 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB5 TVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQ :. : : :: : : .::::.::::.:::: . :.:::.. ::.:::: CCDS47 TIGGKCRE----YRRRHRISS-----FRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQ 280 290 300 310 320 280 290 300 310 320 330 pF1KB5 CRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFC :::::::::: ::: : :::::::::::::::::.::.:::::.: :::::::::::.: CCDS47 CRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYC 330 340 350 360 370 380 340 350 360 370 pF1KB5 RQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA :.::::::::.:..:::..:. ::. ::.::..:. CCDS47 RKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN 390 400 410 420 >>CCDS5374.1 CDCA7L gene_id:55536|Hs108|chr7 (454 aa) initn: 937 init1: 728 opt: 739 Z-score: 680.9 bits: 134.9 E(32554): 1.3e-31 Smith-Waterman score: 957; 45.5% identity (67.4% similar) in 365 aa overlap (31-367:105-450) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :. :::. :..:.. . . ... :. CCDS53 EDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPR-RS 80 90 100 110 120 130 70 80 90 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQ-------------------------PS ::. : : ::::..::... . .:.. :.: CCDS53 RSR-RSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQR 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB5 ENSVTDSNSDSEDES--GMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSD :.:...:..::.::: . . : ::..:::.::::::.:..::.:.: : : : : CCDS53 EDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVR--TPTSA 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB5 SQSRRPRRRTFPGVASRR-NPERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRK :... :: : .:: :: : ::: . .:. . . . .... :.:: CCDS53 SRKKTVRRAFSEGQITRRMNPTRSARPPEKF------ALENFTVSAAKFAEEFYSFRRRK 260 270 280 290 300 220 230 240 250 260 270 pF1KB5 TVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQ :. : : :: : : .::::.::::.:::: . :.:::.. ::.:::: CCDS53 TIGGKCRE----YRRRHRISS-----FRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQ 310 320 330 340 350 280 290 300 310 320 330 pF1KB5 CRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFC :::::::::: ::: : :::::::::::::::::.::.:::::.: :::::::::::.: CCDS53 CRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYC 360 370 380 390 400 410 340 350 360 370 pF1KB5 RQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA :.::::::::.:..:::..:. ::. ::.::..:. CCDS53 RKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN 420 430 440 450 371 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:55:37 2016 done: Sat Nov 5 14:55:38 2016 Total Scan time: 2.870 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]