FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5801, 371 aa 1>>>pF1KB5801 371 - 371 aa - 371 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9931+/-0.000335; mu= 9.9293+/- 0.021 mean_var=134.9618+/-26.148, 0's: 0 Z-trim(119.3): 8 B-trim: 0 in 0/56 Lambda= 0.110400 statistics sampled from 33207 (33214) to 33207 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.389), width: 16 Scan time: 6.930 The best scores are: opt bits E(85289) NP_665809 (OMIM: 609937,616910) cell division cycl ( 371) 2548 416.9 3.7e-116 XP_011510259 (OMIM: 609937,616910) PREDICTED: cell ( 423) 2246 368.9 1.2e-101 NP_114148 (OMIM: 609937,616910) cell division cycl ( 450) 2246 368.9 1.3e-101 NP_001120843 (OMIM: 609685) cell division cycle-as ( 408) 739 128.8 2.1e-29 NP_001120842 (OMIM: 609685) cell division cycle-as ( 420) 739 128.8 2.2e-29 NP_061189 (OMIM: 609685) cell division cycle-assoc ( 454) 739 128.9 2.3e-29 >>NP_665809 (OMIM: 609937,616910) cell division cycle-as (371 aa) initn: 2548 init1: 2548 opt: 2548 Z-score: 2206.5 bits: 416.9 E(85289): 3.7e-116 Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGMNFLEKRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGMNFLEKRAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRARPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 NIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRARPL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 PVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 LRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYL 310 320 330 340 350 360 370 pF1KB5 KSLKQEFEMQA ::::::::::: NP_665 KSLKQEFEMQA 370 >>XP_011510259 (OMIM: 609937,616910) PREDICTED: cell div (423 aa) initn: 2233 init1: 2233 opt: 2246 Z-score: 1945.7 bits: 368.9 E(85289): 1.2e-101 Smith-Waterman score: 2246; 93.7% identity (97.4% similar) in 349 aa overlap (24-371:75-423) 10 20 30 40 50 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFAN-TRLQ .: .. ..:.:.: .:. ... . ::: XP_011 ESFCGFSESEVQDVLDHCGFLQKPRPDVTNELAGIFHADSDDESFCGFSESEIQDGMRLQ 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB5 SVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGM 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB5 NFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRN 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB5 PERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSS 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB5 VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGV 290 300 310 320 330 340 300 310 320 330 340 350 pF1KB5 RGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHG 350 360 370 380 390 400 360 370 pF1KB5 FGNVHAYLKSLKQEFEMQA ::::::::::::::::::: XP_011 FGNVHAYLKSLKQEFEMQA 410 420 >>NP_114148 (OMIM: 609937,616910) cell division cycle-as (450 aa) initn: 2233 init1: 2233 opt: 2246 Z-score: 1945.4 bits: 368.9 E(85289): 1.3e-101 Smith-Waterman score: 2246; 93.7% identity (97.4% similar) in 349 aa overlap (24-371:102-450) 10 20 30 40 50 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFAN-TRLQ .: .. ..:.:.: .:. ... . ::: NP_114 ESFCGFSESEVQDVLDHCGFLQKPRPDVTNELAGIFHADSDDESFCGFSESEIQDGMRLQ 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB5 SVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGM 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB5 NFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 NFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRN 200 210 220 230 240 250 180 190 200 210 220 230 pF1KB5 PERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 PERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSS 260 270 280 290 300 310 240 250 260 270 280 290 pF1KB5 VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 VTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGV 320 330 340 350 360 370 300 310 320 330 340 350 pF1KB5 RGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 RGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHG 380 390 400 410 420 430 360 370 pF1KB5 FGNVHAYLKSLKQEFEMQA ::::::::::::::::::: NP_114 FGNVHAYLKSLKQEFEMQA 440 450 >-- initn: 356 init1: 318 opt: 318 Z-score: 285.8 bits: 61.8 E(85289): 3.5e-09 Smith-Waterman score: 318; 98.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :::::::::::::::::::::::::::::::::::::::::::::::::. NP_114 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTKPKFRSDISEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGMNFLEKRAL NP_114 LANVFYEDSDNESFCGFSESEVQDVLDHCGFLQKPRPDVTNELAGIFHADSDDESFCGFS 70 80 90 100 110 120 >>NP_001120843 (OMIM: 609685) cell division cycle-associ (408 aa) initn: 937 init1: 728 opt: 739 Z-score: 648.7 bits: 128.8 E(85289): 2.1e-29 Smith-Waterman score: 960; 43.5% identity (66.8% similar) in 391 aa overlap (6-367:33-404) 10 20 30 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSS-S ::.. : ... .: .. .. . :. : NP_001 LATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQVVESDLS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 DDSCDSFASDNFANTRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQ- ::. :..:.. . . ... :.::. : : ::::..::... . .:.. :.: NP_001 DDGKASLVSEEEEDEEEDKATPR-RSRSR-RSSIGLRVAFQFPTKKLANKPDKNSSSEQL 70 80 90 100 110 120 100 110 120 pF1KB5 ------------------------PSENSVTDSNSDSEDES--GMNFLEKRALNIKQNKA :.:...:..::.::: . . : ::..:::.::: NP_001 FSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKA 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB5 MLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRR-NPERRARPLTRSRSR :::.:..::.:.: : : : : :... :: : .:: :: : ::: . NP_001 MLAQLLAELNSMPDFFPVR--TPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKF--- 190 200 210 220 230 190 200 210 220 230 240 pF1KB5 ILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEIT .:. . . . .... :.:::. : : :: : : .::::.:: NP_001 ---ALENFTVSAAKFAEEFYSFRRRKTIGGKCRE----YRRRHRISS-----FRPVEDIT 240 250 260 270 280 250 260 270 280 290 300 pF1KB5 EEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYG ::.:::: . :.:::.. ::.:::::::::::::: ::: : :::::::::::::::: NP_001 EEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYG 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB5 EEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQE :.::.:::::.: :::::::::::.::.::::::::.:..:::..:. ::. ::.::..: NP_001 EDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKE 350 360 370 380 390 400 370 pF1KB5 FEMQA . NP_001 LVEDN >>NP_001120842 (OMIM: 609685) cell division cycle-associ (420 aa) initn: 937 init1: 728 opt: 739 Z-score: 648.6 bits: 128.8 E(85289): 2.2e-29 Smith-Waterman score: 957; 45.5% identity (67.4% similar) in 365 aa overlap (31-367:71-416) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :. :::. :..:.. . . ... :. NP_001 EDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPR-RS 50 60 70 80 90 70 80 90 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQ-------------------------PS ::. : : ::::..::... . .:.. :.: NP_001 RSR-RSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQR 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB5 ENSVTDSNSDSEDES--GMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSD :.:...:..::.::: . . : ::..:::.::::::.:..::.:.: : : : : NP_001 EDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVR--TPTSA 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB5 SQSRRPRRRTFPGVASRR-NPERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRK :... :: : .:: :: : ::: . .:. . . . .... :.:: NP_001 SRKKTVRRAFSEGQITRRMNPTRSARPPEKF------ALENFTVSAAKFAEEFYSFRRRK 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB5 TVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQ :. : : :: : : .::::.::::.:::: . :.:::.. ::.:::: NP_001 TIGGKCRE----YRRRHRISS-----FRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQ 280 290 300 310 320 280 290 300 310 320 330 pF1KB5 CRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFC :::::::::: ::: : :::::::::::::::::.::.:::::.: :::::::::::.: NP_001 CRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYC 330 340 350 360 370 380 340 350 360 370 pF1KB5 RQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA :.::::::::.:..:::..:. ::. ::.::..:. NP_001 RKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN 390 400 410 420 >>NP_061189 (OMIM: 609685) cell division cycle-associate (454 aa) initn: 937 init1: 728 opt: 739 Z-score: 648.1 bits: 128.9 E(85289): 2.3e-29 Smith-Waterman score: 957; 45.5% identity (67.4% similar) in 365 aa overlap (31-367:105-450) 10 20 30 40 50 60 pF1KB5 MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRT :. :::. :..:.. . . ... :. NP_061 EDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPR-RS 80 90 100 110 120 130 70 80 90 pF1KB5 RSQCRHSGPLRVAMKFPARSTRGATNKKAESRQ-------------------------PS ::. : : ::::..::... . .:.. :.: NP_061 RSR-RSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQR 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB5 ENSVTDSNSDSEDES--GMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSD :.:...:..::.::: . . : ::..:::.::::::.:..::.:.: : : : : NP_061 EDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVR--TPTSA 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB5 SQSRRPRRRTFPGVASRR-NPERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRK :... :: : .:: :: : ::: . .:. . . . .... :.:: NP_061 SRKKTVRRAFSEGQITRRMNPTRSARPPEKF------ALENFTVSAAKFAEEFYSFRRRK 260 270 280 290 300 220 230 240 250 260 270 pF1KB5 TVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQ :. : : :: : : .::::.::::.:::: . :.:::.. ::.:::: NP_061 TIGGKCRE----YRRRHRISS-----FRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQ 310 320 330 340 350 280 290 300 310 320 330 pF1KB5 CRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFC :::::::::: ::: : :::::::::::::::::.::.:::::.: :::::::::::.: NP_061 CRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYC 360 370 380 390 400 410 340 350 360 370 pF1KB5 RQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA :.::::::::.:..:::..:. ::. ::.::..:. NP_061 RKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN 420 430 440 450 371 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:55:38 2016 done: Sat Nov 5 14:55:39 2016 Total Scan time: 6.930 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]