Result of FASTA (omim) for
pF1KB5808
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5808, 454 aa
1>>>pF1KB5808 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3262+/-0.000287; mu= 10.6459+/- 0.018
mean_var=151.7486+/-31.082, 0's: 0 Z-trim(122.9): 412 B-trim: 1721 in 2/59
Lambda= 0.104115
statistics sampled from 41424 (41837) to 41424 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.491), width: 16
Scan time: 10.470
The best scores are: opt bits E(85289)
NP_000957 (OMIM: 180190) retinoic acid receptor ga ( 454) 3103 477.3 3.7e-134
NP_001036193 (OMIM: 180190) retinoic acid receptor ( 443) 2700 416.7 6.1e-116
NP_001230659 (OMIM: 180190) retinoic acid receptor ( 382) 2618 404.4 2.8e-112
NP_001230661 (OMIM: 180190) retinoic acid receptor ( 432) 2325 360.4 5.4e-99
NP_001230660 (OMIM: 180190) retinoic acid receptor ( 333) 2244 348.1 2e-95
NP_001277145 (OMIM: 180220,615524) retinoic acid r ( 455) 2214 343.7 5.9e-94
NP_000956 (OMIM: 180220,615524) retinoic acid rece ( 448) 2199 341.5 2.8e-93
NP_001277195 (OMIM: 180220,615524) retinoic acid r ( 399) 2171 337.2 4.7e-92
NP_001277229 (OMIM: 180220,615524) retinoic acid r ( 405) 2171 337.2 4.7e-92
XP_005257610 (OMIM: 180240,612376) PREDICTED: reti ( 462) 2167 336.7 8e-92
NP_000955 (OMIM: 180240,612376) retinoic acid rece ( 462) 2167 336.7 8e-92
XP_005257611 (OMIM: 180240,612376) PREDICTED: reti ( 462) 2167 336.7 8e-92
NP_001138773 (OMIM: 180240,612376) retinoic acid r ( 462) 2167 336.7 8e-92
XP_011523397 (OMIM: 180240,612376) PREDICTED: reti ( 462) 2167 336.7 8e-92
XP_005257609 (OMIM: 180240,612376) PREDICTED: reti ( 478) 2130 331.1 3.8e-90
NP_001019980 (OMIM: 180240,612376) retinoic acid r ( 457) 2124 330.2 6.9e-90
XP_011523398 (OMIM: 180240,612376) PREDICTED: reti ( 404) 2121 329.7 8.6e-90
NP_001277205 (OMIM: 180220,615524) retinoic acid r ( 336) 1777 278.0 2.7e-74
NP_001277146 (OMIM: 180220,615524) retinoic acid r ( 336) 1777 278.0 2.7e-74
NP_057236 (OMIM: 180220,615524) retinoic acid rece ( 336) 1777 278.0 2.7e-74
XP_016880409 (OMIM: 180240,612376) PREDICTED: reti ( 343) 1731 271.1 3.3e-72
NP_001138774 (OMIM: 180240,612376) retinoic acid r ( 365) 1460 230.4 6.2e-60
NP_001277206 (OMIM: 180220,615524) retinoic acid r ( 402) 1315 208.7 2.4e-53
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 739 122.2 2.8e-27
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 739 122.2 2.9e-27
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 728 120.5 7.7e-27
XP_006719426 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 725 120.2 1.5e-26
NP_002126 (OMIM: 139139) nuclear receptor subfamil ( 598) 725 120.2 1.5e-26
NP_775180 (OMIM: 139139) nuclear receptor subfamil ( 598) 725 120.2 1.5e-26
XP_005268881 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 725 120.2 1.5e-26
XP_006719427 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 725 120.2 1.5e-26
XP_016874736 (OMIM: 139139) PREDICTED: nuclear rec ( 602) 725 120.2 1.6e-26
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 724 120.0 1.6e-26
NP_001189162 (OMIM: 139139) nuclear receptor subfa ( 611) 725 120.2 1.6e-26
NP_001189163 (OMIM: 139139) nuclear receptor subfa ( 652) 725 120.2 1.6e-26
XP_005268879 (OMIM: 139139) PREDICTED: nuclear rec ( 670) 725 120.2 1.7e-26
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 712 118.1 4.5e-26
NP_001230443 (OMIM: 602969) estrogen-related recep ( 435) 712 118.1 4.7e-26
NP_996317 (OMIM: 602969) estrogen-related receptor ( 435) 712 118.1 4.7e-26
NP_001230442 (OMIM: 602969) estrogen-related recep ( 435) 712 118.1 4.7e-26
NP_001230440 (OMIM: 602969) estrogen-related recep ( 435) 712 118.1 4.7e-26
NP_001127757 (OMIM: 602969) estrogen-related recep ( 435) 712 118.1 4.7e-26
XP_016856131 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 712 118.1 4.7e-26
XP_016856133 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 712 118.1 4.7e-26
NP_001230444 (OMIM: 602969) estrogen-related recep ( 435) 712 118.1 4.7e-26
XP_016856134 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 712 118.1 4.7e-26
XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 712 118.1 4.7e-26
XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 712 118.1 4.7e-26
XP_016856129 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 712 118.1 4.7e-26
NP_001230441 (OMIM: 602969) estrogen-related recep ( 435) 712 118.1 4.7e-26
>>NP_000957 (OMIM: 180190) retinoic acid receptor gamma (454 aa)
initn: 3103 init1: 3103 opt: 3103 Z-score: 2529.5 bits: 477.3 E(85289): 3.7e-134
Smith-Waterman score: 3103; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
370 380 390 400 410 420
430 440 450
pF1KB5 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::::::::::::::::::::::::::::::::::
NP_000 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
430 440 450
>>NP_001036193 (OMIM: 180190) retinoic acid receptor gam (443 aa)
initn: 2724 init1: 2692 opt: 2700 Z-score: 2202.5 bits: 416.7 E(85289): 6.1e-116
Smith-Waterman score: 2700; 92.3% identity (93.7% similar) in 442 aa overlap (13-454:9-443)
10 20 30 40 50 60
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
: :: : .:: : : : :: . . : :: . :. .
NP_001 MYDCMETFAPGPRRLYGAAG-PGA--GLLRRATG----GSCFAGLESFAWPQPASL
10 20 30 40
70 80 90 100 110 120
pF1KB5 LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
350 360 370 380 390 400
430 440 450
pF1KB5 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::::::::::::::::::::::::::::::::::
NP_001 MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
410 420 430 440
>>NP_001230659 (OMIM: 180190) retinoic acid receptor gam (382 aa)
initn: 2618 init1: 2618 opt: 2618 Z-score: 2136.8 bits: 404.4 E(85289): 2.8e-112
Smith-Waterman score: 2618; 100.0% identity (100.0% similar) in 382 aa overlap (73-454:1-382)
50 60 70 80 90 100
pF1KB5 SPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHY
::::::::::::::::::::::::::::::
NP_001 MVPSSPSPPPPPRVYKPCFVCNDKSSGYHY
10 20 30
110 120 130 140 150 160
pF1KB5 GVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 DRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 DLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 QDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 DLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKM
280 290 300 310 320 330
410 420 430 440 450
pF1KB5 EIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
340 350 360 370 380
>>NP_001230661 (OMIM: 180190) retinoic acid receptor gam (432 aa)
initn: 2325 init1: 2325 opt: 2325 Z-score: 1898.2 bits: 360.4 E(85289): 5.4e-99
Smith-Waterman score: 2325; 99.7% identity (100.0% similar) in 345 aa overlap (110-454:88-432)
80 90 100 110 120 130
pF1KB5 PPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTR
:.::::::::::::::::::::::::::::
NP_001 PGPGPACCAEPPAAPVSPDLNLLPGRNPPACNGFFRRSIQKNMVYTCHRDKNCIINKVTR
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB5 NRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQE
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB5 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB5 ITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLL
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB5 PLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRM
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB5 LMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSED
360 370 380 390 400 410
440 450
pF1KB5 EVPGGQGKGGLKSPA
:::::::::::::::
NP_001 EVPGGQGKGGLKSPA
420 430
>>NP_001230660 (OMIM: 180190) retinoic acid receptor gam (333 aa)
initn: 2244 init1: 2244 opt: 2244 Z-score: 1834.0 bits: 348.1 E(85289): 2e-95
Smith-Waterman score: 2244; 100.0% identity (100.0% similar) in 333 aa overlap (122-454:1-333)
100 110 120 130 140 150
pF1KB5 VCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCF
::::::::::::::::::::::::::::::
NP_001 MVYTCHRDKNCIINKVTRNRCQYCRLQKCF
10 20 30
160 170 180 190 200 210
pF1KB5 EVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYT
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 TNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDIL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 MLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLL
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 SAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGIST
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 KGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLK
280 290 300 310 320 330
pF1KB5 SPA
:::
NP_001 SPA
>>NP_001277145 (OMIM: 180220,615524) retinoic acid recep (455 aa)
initn: 2209 init1: 2160 opt: 2214 Z-score: 1807.8 bits: 343.7 E(85289): 5.9e-94
Smith-Waterman score: 2214; 74.3% identity (87.4% similar) in 444 aa overlap (15-453:15-452)
10 20 30 40 50
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGS--PPFEMLS--PSFRGLGQPDLPK
: . ::.. .:. :: .. : ::.. : : : . :. :
NP_001 MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPS-PA
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 EMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRR
..:::::::::.::: ::: ::::::::::::.:::::::::::.::::::::::
NP_001 -----TIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGS
::::::.:::::::::.:::::::::::::::::::::::::.:::::::::::....
NP_001 SIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQEC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 PDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATK
.:::.. .:..: :. ::::::::::::::::::::::::::.:::::::::::::::
NP_001 TESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 CIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR
::::::::::::::::::.::::::::::::::::.::::::::::::::::::::::::
NP_001 CIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 TQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEP
::::::::::::::::.::.:::::::::::::::::::::::::.::::: ::::::::
NP_001 TQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 LLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREML
:::::..: :.::::.:.:::..::::::::.::.:::::.::::::::: :::::.:::
NP_001 LLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEML
360 370 380 390 400 410
420 430 440 450
pF1KB5 ENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGL-KSPA
:: : : . . . . : . :.. ..:. .::
NP_001 ENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
420 430 440 450
>>NP_000956 (OMIM: 180220,615524) retinoic acid receptor (448 aa)
initn: 2230 init1: 2193 opt: 2199 Z-score: 1795.7 bits: 341.5 E(85289): 2.8e-93
Smith-Waterman score: 2199; 78.0% identity (90.6% similar) in 413 aa overlap (42-453:33-445)
20 30 40 50 60 70
pF1KB5 GALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSE
:. : :: : . .. .. :.::::::::
NP_000 DCMDVLSVSPGQILDFYTASPSSCMLQEKALKACFSGLTQTEWQHRHTAQSIETQSTSSE
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKN
:.::: ::: ::::::::::::.:::::::::::.::::::::::::::::.::::::::
NP_000 ELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKN
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 CIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELIT
:.:::::::::::::::::::::::::.:::::::::::.... .:::.. .:..:
NP_000 CVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 KVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGF
:. ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_000 KIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGF
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB5 TGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLV
:::.::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_000 TGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLV
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB5 FAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPS
:.::.:::::::::::::::::::::::::.::::: :::::::::::::..: :.::::
NP_000 FTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPS
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB5 QPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGP
.:.:::..::::::::.::.:::::.::::::::: :::::.::::: : : . . .
NP_000 KPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSG
370 380 390 400 410 420
440 450
pF1KB5 HPNASSEDEVPGGQGKGGL-KSPA
. : . :.. ..:. .::
NP_000 NTAEHSPSISPSSVENSGVSQSPLVQ
430 440
>>NP_001277195 (OMIM: 180220,615524) retinoic acid recep (399 aa)
initn: 2197 init1: 2160 opt: 2171 Z-score: 1773.7 bits: 337.2 E(85289): 4.7e-92
Smith-Waterman score: 2171; 80.4% identity (92.4% similar) in 393 aa overlap (62-453:4-396)
40 50 60 70 80 90
pF1KB5 ALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCF
..:::::::::.::: ::: ::::::::::
NP_001 MENAIETQSTSSEELVPSPPSPLPPPRVYKPCF
10 20 30
100 110 120 130 140 150
pF1KB5 VCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCF
::.:::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::
NP_001 VCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 EVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYT
:::::::.:::::::::::.... .:::.. .:..: :. :::::::::::::::::
NP_001 EVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 TNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDIL
:::::::::.:::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 TNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDIL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 MLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLL
.::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::::
NP_001 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 SAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGIST
::::::::::.::::: :::::::::::::..: :.::::.:.:::..::::::::.::.
NP_001 SAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 KGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGL-
:::::.::::::::: :::::.::::: : : . . . . : . :.. ..:.
NP_001 KGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVS
340 350 360 370 380 390
pF1KB5 KSPA
.::
NP_001 QSPLVQ
>>NP_001277229 (OMIM: 180220,615524) retinoic acid recep (405 aa)
initn: 2221 init1: 2160 opt: 2171 Z-score: 1773.6 bits: 337.2 E(85289): 4.7e-92
Smith-Waterman score: 2171; 80.4% identity (92.4% similar) in 393 aa overlap (62-453:10-402)
40 50 60 70 80 90
pF1KB5 ALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCF
..:::::::::.::: ::: ::::::::::
NP_001 MKLSRIAFPAIETQSTSSEELVPSPPSPLPPPRVYKPCF
10 20 30
100 110 120 130 140 150
pF1KB5 VCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCF
::.:::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::
NP_001 VCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 EVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYT
:::::::.:::::::::::.... .:::.. .:..: :. :::::::::::::::::
NP_001 EVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 TNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDIL
:::::::::.:::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 TNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDIL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 MLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLL
.::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::::
NP_001 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 SAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGIST
::::::::::.::::: :::::::::::::..: :.::::.:.:::..::::::::.::.
NP_001 SAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 KGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGL-
:::::.::::::::: :::::.::::: : : . . . . : . :.. ..:.
NP_001 KGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVS
340 350 360 370 380 390
pF1KB5 KSPA
.::
NP_001 QSPLVQ
400
>>XP_005257610 (OMIM: 180240,612376) PREDICTED: retinoic (462 aa)
initn: 2195 init1: 2121 opt: 2167 Z-score: 1769.5 bits: 336.7 E(85289): 8e-92
Smith-Waterman score: 2176; 72.1% identity (84.5% similar) in 458 aa overlap (1-453:1-440)
10 20 30 40 50
pF1KB5 MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRG-SPPFEMLSPSFR----GLGQPDLP
::.:. . :. : .::: . : :: : : ::: . . . . : . :. :
XP_005 MASNSSSCPTPGG-GHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPS-P
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 KEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFR
..::::.::::.::: ::::: ::.:::::::.:::::::::::.:::::::::
XP_005 A-----TIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 RSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEG
:::::::::::::::::::::::::::::::::::::::::::.:::::::::::: .
XP_005 RSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELAT
.:: :.:.. ::: :: ::::::::.::::::::::.:...::.::. ::::::::.:
XP_005 CSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELST
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 KCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLN
::::: :::::.::::: :.::::::::::::::::.:::::::::::::::::::::::
XP_005 KCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 RTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQE
::::::::::::::::::::.:::::::::.:::::::::::::::.:::.:..:: :::
XP_005 RTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 PLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREM
::::::..:.:.::::.:.:::.:::::::::.::.:::::.::::::::: :::::.::
XP_005 PLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEM
360 370 380 390 400 410
420 430 440 450
pF1KB5 LENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
::: : .. :.::: ::. ::: :
XP_005 LENSEGLDTLSGQPGG-----------GGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
420 430 440 450 460
454 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:23:40 2016 done: Sat Nov 5 10:23:41 2016
Total Scan time: 10.470 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]