FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5822, 543 aa 1>>>pF1KB5822 543 - 543 aa - 543 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.4505+/-0.000353; mu= -3.5372+/- 0.022 mean_var=303.5517+/-61.915, 0's: 0 Z-trim(124.1): 50 B-trim: 35 in 1/53 Lambda= 0.073614 statistics sampled from 45102 (45166) to 45102 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.53), width: 16 Scan time: 11.620 The best scores are: opt bits E(85289) NP_001161299 (OMIM: 600744) transcription factor E ( 490) 3244 357.8 4.5e-98 XP_005249468 (OMIM: 600744) PREDICTED: transcripti ( 476) 3198 352.9 1.3e-96 XP_005249469 (OMIM: 600744) PREDICTED: transcripti ( 476) 3198 352.9 1.3e-96 XP_006715275 (OMIM: 600744) PREDICTED: transcripti ( 476) 3198 352.9 1.3e-96 XP_011513218 (OMIM: 600744) PREDICTED: transcripti ( 476) 3198 352.9 1.3e-96 NP_009093 (OMIM: 600744) transcription factor EB i ( 476) 3198 352.9 1.3e-96 XP_006715276 (OMIM: 600744) PREDICTED: transcripti ( 476) 3198 352.9 1.3e-96 XP_011513217 (OMIM: 600744) PREDICTED: transcripti ( 476) 3198 352.9 1.3e-96 NP_001258873 (OMIM: 600744) transcription factor E ( 476) 3198 352.9 1.3e-96 NP_001258874 (OMIM: 600744) transcription factor E ( 476) 3198 352.9 1.3e-96 NP_001258872 (OMIM: 600744) transcription factor E ( 391) 2138 240.3 8.6e-63 NP_006512 (OMIM: 300854,314310) transcription fact ( 575) 1129 133.2 2.1e-30 NP_001269071 (OMIM: 300854,314310) transcription f ( 470) 1111 131.2 6.7e-30 XP_011514265 (OMIM: 604732) PREDICTED: transcripti ( 437) 811 99.4 2.5e-20 XP_011514266 (OMIM: 604732) PREDICTED: transcripti ( 437) 811 99.4 2.5e-20 XP_011514268 (OMIM: 604732) PREDICTED: transcripti ( 437) 811 99.4 2.5e-20 XP_011514267 (OMIM: 604732) PREDICTED: transcripti ( 437) 811 99.4 2.5e-20 XP_016861937 (OMIM: 103470,103500,156845,193510,61 ( 468) 770 95.0 5.4e-19 NP_001171896 (OMIM: 103470,103500,156845,193510,61 ( 468) 770 95.0 5.4e-19 XP_016861936 (OMIM: 103470,103500,156845,193510,61 ( 503) 770 95.1 5.7e-19 NP_937820 (OMIM: 103470,103500,156845,193510,61445 ( 504) 770 95.1 5.7e-19 XP_016861934 (OMIM: 103470,103500,156845,193510,61 ( 519) 770 95.1 5.8e-19 NP_006713 (OMIM: 103470,103500,156845,193510,61445 ( 519) 770 95.1 5.8e-19 NP_937802 (OMIM: 103470,103500,156845,193510,61445 ( 520) 770 95.1 5.8e-19 NP_937821 (OMIM: 103470,103500,156845,193510,61445 ( 357) 755 93.3 1.3e-18 NP_937801 (OMIM: 103470,103500,156845,193510,61445 ( 413) 755 93.4 1.5e-18 XP_011532028 (OMIM: 103470,103500,156845,193510,61 ( 464) 755 93.4 1.6e-18 NP_036384 (OMIM: 604732) transcription factor EC i ( 347) 728 90.5 9.4e-18 XP_016867364 (OMIM: 604732) PREDICTED: transcripti ( 347) 728 90.5 9.4e-18 NP_000239 (OMIM: 103470,103500,156845,193510,61445 ( 419) 706 88.2 5.5e-17 XP_011532027 (OMIM: 103470,103500,156845,193510,61 ( 470) 706 88.2 6e-17 XP_006713227 (OMIM: 103470,103500,156845,193510,61 ( 474) 706 88.2 6e-17 XP_011532025 (OMIM: 103470,103500,156845,193510,61 ( 509) 706 88.3 6.3e-17 XP_016861935 (OMIM: 103470,103500,156845,193510,61 ( 509) 706 88.3 6.3e-17 XP_005264812 (OMIM: 103470,103500,156845,193510,61 ( 510) 706 88.3 6.4e-17 XP_011532024 (OMIM: 103470,103500,156845,193510,61 ( 525) 706 88.3 6.5e-17 XP_016861933 (OMIM: 103470,103500,156845,193510,61 ( 525) 706 88.3 6.5e-17 XP_005264811 (OMIM: 103470,103500,156845,193510,61 ( 526) 706 88.3 6.5e-17 XP_011514274 (OMIM: 604732) PREDICTED: transcripti ( 287) 686 85.9 1.8e-16 XP_016867365 (OMIM: 604732) PREDICTED: transcripti ( 259) 669 84.1 5.8e-16 NP_001231512 (OMIM: 604732) transcription factor E ( 280) 669 84.1 6.1e-16 NP_001018068 (OMIM: 604732) transcription factor E ( 318) 669 84.2 6.7e-16 XP_016867363 (OMIM: 604732) PREDICTED: transcripti ( 408) 669 84.3 8.2e-16 XP_011514272 (OMIM: 604732) PREDICTED: transcripti ( 408) 669 84.3 8.2e-16 XP_016867366 (OMIM: 604732) PREDICTED: transcripti ( 239) 636 80.6 6.1e-15 XP_016867367 (OMIM: 604732) PREDICTED: transcripti ( 239) 636 80.6 6.1e-15 XP_011514271 (OMIM: 604732) PREDICTED: transcripti ( 418) 452 61.2 7.2e-09 >>NP_001161299 (OMIM: 600744) transcription factor EB is (490 aa) initn: 3244 init1: 3244 opt: 3244 Z-score: 1881.8 bits: 357.8 E(85289): 4.5e-98 Smith-Waterman score: 3244; 100.0% identity (100.0% similar) in 483 aa overlap (61-543:8-490) 40 50 60 70 80 90 pF1KB5 VPVILASPCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRE :::::::::::::::::::::::::::::: NP_001 MTASSGWEPAPAATMASRIGLRMQLMREQAQQEEQRE 10 20 30 100 110 120 130 140 150 pF1KB5 RMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 LQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 MAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTAS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 LVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIP 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 KANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQA 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 RVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPL 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 PTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLL 400 410 420 430 440 450 520 530 540 pF1KB5 PLASDPLLSTMSPEASKASSRRSSFSMEEGDVL ::::::::::::::::::::::::::::::::: NP_001 PLASDPLLSTMSPEASKASSRRSSFSMEEGDVL 460 470 480 490 >>XP_005249468 (OMIM: 600744) PREDICTED: transcription f (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: XP_005 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: XP_005 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>XP_005249469 (OMIM: 600744) PREDICTED: transcription f (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: XP_005 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: XP_005 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>XP_006715275 (OMIM: 600744) PREDICTED: transcription f (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: XP_006 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: XP_006 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>XP_011513218 (OMIM: 600744) PREDICTED: transcription f (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: XP_011 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: XP_011 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>NP_009093 (OMIM: 600744) transcription factor EB isofo (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: NP_009 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: NP_009 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>XP_006715276 (OMIM: 600744) PREDICTED: transcription f (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: XP_006 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: XP_006 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>XP_011513217 (OMIM: 600744) PREDICTED: transcription f (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: XP_011 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: XP_011 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>NP_001258873 (OMIM: 600744) transcription factor EB is (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: NP_001 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: NP_001 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 >>NP_001258874 (OMIM: 600744) transcription factor EB is (476 aa) initn: 3198 init1: 3198 opt: 3198 Z-score: 1855.5 bits: 352.9 E(85289): 1.3e-96 Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 476 aa overlap (68-543:1-476) 40 50 60 70 80 90 pF1KB5 PCQPLCFEEDTCLIYLLPLLIHREPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAV :::::::::::::::::::::::::::::: NP_001 MASRIGLRMQLMREQAQQEEQRERMQQQAV 10 20 30 100 110 120 130 140 150 pF1KB5 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB5 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPL 400 410 420 430 440 450 520 530 540 pF1KB5 LSTMSPEASKASSRRSSFSMEEGDVL :::::::::::::::::::::::::: NP_001 LSTMSPEASKASSRRSSFSMEEGDVL 460 470 543 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:26:17 2016 done: Sat Nov 5 10:26:18 2016 Total Scan time: 11.620 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]