FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5824, 476 aa 1>>>pF1KB5824 476 - 476 aa - 476 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1644+/-0.000644; mu= -10.9527+/- 0.038 mean_var=668.1163+/-151.845, 0's: 0 Z-trim(115.3): 1583 B-trim: 565 in 1/54 Lambda= 0.049619 statistics sampled from 23469 (25742) to 23469 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.302), width: 16 Scan time: 7.920 The best scores are: opt bits E(85289) XP_016872635 (OMIM: 603078) PREDICTED: serine/thre ( 476) 3238 248.0 4.3e-65 NP_001107594 (OMIM: 603078) serine/threonine-prote ( 476) 3238 248.0 4.3e-65 NP_001265 (OMIM: 603078) serine/threonine-protein ( 476) 3238 248.0 4.3e-65 NP_001107593 (OMIM: 603078) serine/threonine-prote ( 476) 3238 248.0 4.3e-65 NP_001231775 (OMIM: 603078) serine/threonine-prote ( 442) 2825 218.4 3.3e-56 XP_011540864 (OMIM: 603078) PREDICTED: serine/thre ( 409) 2593 201.7 3.1e-51 NP_001317356 (OMIM: 603078) serine/threonine-prote ( 492) 2593 201.8 3.5e-51 XP_011540862 (OMIM: 603078) PREDICTED: serine/thre ( 492) 2593 201.8 3.5e-51 NP_001317357 (OMIM: 603078) serine/threonine-prote ( 382) 2588 201.3 3.8e-51 NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 589 58.6 6.5e-08 NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 589 58.6 6.5e-08 NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 589 58.6 6.5e-08 XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 589 58.6 6.6e-08 XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 589 58.7 6.6e-08 XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 589 58.7 6.6e-08 XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 589 58.7 6.6e-08 NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 589 58.7 6.6e-08 XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 589 58.7 6.6e-08 XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 589 58.7 6.7e-08 XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 589 58.7 6.7e-08 XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 589 58.7 6.8e-08 NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 589 58.7 6.9e-08 XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 589 58.7 6.9e-08 XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 589 58.7 6.9e-08 XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 589 58.7 6.9e-08 XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 589 58.7 7e-08 XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 575 57.6 1.2e-07 NP_056006 (OMIM: 608973) serine/threonine-protein ( 926) 579 58.1 1.2e-07 XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 575 57.6 1.3e-07 NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 575 57.6 1.3e-07 XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 575 57.6 1.3e-07 XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 575 57.6 1.3e-07 NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 575 57.6 1.3e-07 XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 575 57.6 1.3e-07 XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 575 57.7 1.3e-07 XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 575 57.7 1.3e-07 NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 575 57.7 1.3e-07 NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 575 57.7 1.3e-07 NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 573 57.5 1.5e-07 XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 573 57.5 1.5e-07 XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 573 57.5 1.5e-07 NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 573 57.6 1.5e-07 NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 573 57.6 1.5e-07 NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 560 56.5 2.7e-07 NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752) 560 56.6 2.8e-07 XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 551 55.5 3e-07 NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 554 56.2 3.9e-07 NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 551 55.8 3.9e-07 XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 551 55.9 4.1e-07 XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 551 55.9 4.1e-07 >>XP_016872635 (OMIM: 603078) PREDICTED: serine/threonin (476 aa) initn: 3238 init1: 3238 opt: 3238 Z-score: 1289.7 bits: 248.0 E(85289): 4.3e-65 Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB5 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 430 440 450 460 470 >>NP_001107594 (OMIM: 603078) serine/threonine-protein k (476 aa) initn: 3238 init1: 3238 opt: 3238 Z-score: 1289.7 bits: 248.0 E(85289): 4.3e-65 Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB5 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 430 440 450 460 470 >>NP_001265 (OMIM: 603078) serine/threonine-protein kina (476 aa) initn: 3238 init1: 3238 opt: 3238 Z-score: 1289.7 bits: 248.0 E(85289): 4.3e-65 Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB5 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 430 440 450 460 470 >>NP_001107593 (OMIM: 603078) serine/threonine-protein k (476 aa) initn: 3238 init1: 3238 opt: 3238 Z-score: 1289.7 bits: 248.0 E(85289): 4.3e-65 Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB5 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 430 440 450 460 470 >>NP_001231775 (OMIM: 603078) serine/threonine-protein k (442 aa) initn: 2825 init1: 2825 opt: 2825 Z-score: 1130.2 bits: 218.4 E(85289): 3.3e-56 Smith-Waterman score: 2953; 92.9% identity (92.9% similar) in 476 aa overlap (1-476:1-442) 10 20 30 40 50 60 pF1KB5 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQ--------- 370 380 390 400 410 430 440 450 460 470 pF1KB5 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT ::::::::::::::::::::::::::::::: NP_001 -------------------------GDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 420 430 440 >>XP_011540864 (OMIM: 603078) PREDICTED: serine/threonin (409 aa) initn: 2588 init1: 2588 opt: 2593 Z-score: 1040.8 bits: 201.7 E(85289): 3.1e-51 Smith-Waterman score: 2593; 97.4% identity (98.2% similar) in 391 aa overlap (86-476:19-409) 60 70 80 90 100 110 pF1KB5 ICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLM .:. : .:::::::::::::::::: XP_011 MPRCSVESWQCPLWKTGTWCKPWEKVPMEKPDIGMPEPDAQRFFHQLM 10 20 30 40 120 130 140 150 160 170 pF1KB5 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB5 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKID 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB5 SAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQ 170 180 190 200 210 220 300 310 320 330 340 350 pF1KB5 SNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLL 230 240 250 260 270 280 360 370 380 390 400 410 pF1KB5 NSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTIS 290 300 310 320 330 340 420 430 440 450 460 470 pF1KB5 TTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPA 350 360 370 380 390 400 pF1KB5 T : XP_011 T >>NP_001317356 (OMIM: 603078) serine/threonine-protein k (492 aa) initn: 2588 init1: 2588 opt: 2593 Z-score: 1040.0 bits: 201.8 E(85289): 3.5e-51 Smith-Waterman score: 2593; 97.4% identity (98.2% similar) in 391 aa overlap (86-476:102-492) 60 70 80 90 100 110 pF1KB5 ICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLM .:. : .:::::::::::::::::: NP_001 AFGFLQWWAKDSPPRCSVESWQCPLWKTGTWCKPWEKVPMEKPDIGMPEPDAQRFFHQLM 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB5 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB5 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKID 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB5 SAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQ 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 SNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLL 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 NSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTIS 380 390 400 410 420 430 420 430 440 450 460 470 pF1KB5 TTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPA 440 450 460 470 480 490 pF1KB5 T : NP_001 T >>XP_011540862 (OMIM: 603078) PREDICTED: serine/threonin (492 aa) initn: 2588 init1: 2588 opt: 2593 Z-score: 1040.0 bits: 201.8 E(85289): 3.5e-51 Smith-Waterman score: 2593; 97.4% identity (98.2% similar) in 391 aa overlap (86-476:102-492) 60 70 80 90 100 110 pF1KB5 ICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLM .:. : .:::::::::::::::::: XP_011 AFGFLQWWAKDSPPRCSVESWQCPLWKTGTWCKPWEKVPMEKPDIGMPEPDAQRFFHQLM 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB5 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB5 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKID 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB5 SAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQ 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 SNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLL 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 NSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTIS 380 390 400 410 420 430 420 430 440 450 460 470 pF1KB5 TTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPA 440 450 460 470 480 490 pF1KB5 T : XP_011 T >>NP_001317357 (OMIM: 603078) serine/threonine-protein k (382 aa) initn: 2588 init1: 2588 opt: 2588 Z-score: 1039.1 bits: 201.3 E(85289): 3.8e-51 Smith-Waterman score: 2588; 99.7% identity (100.0% similar) in 380 aa overlap (97-476:3-382) 70 80 90 100 110 120 pF1KB5 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI .::::::::::::::::::::::::::::: NP_001 MEKPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 10 20 30 130 140 150 160 170 180 pF1KB5 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB5 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB5 VENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSA 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB5 SSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSS 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB5 QNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRRNNKLIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRRNNKLIF 280 290 300 310 320 330 430 440 450 460 470 pF1KB5 KVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 340 350 360 370 380 >>NP_001156769 (OMIM: 600526) serine/threonine-protein k (709 aa) initn: 529 init1: 263 opt: 589 Z-score: 263.1 bits: 58.6 E(85289): 6.5e-08 Smith-Waterman score: 594; 30.8% identity (59.4% similar) in 461 aa overlap (4-430:48-493) 10 20 30 pF1KB5 MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEE : . .. :..:.:.: ...:.:: . .: . NP_001 QPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 AVAVKIVDMKRAVDCP--ENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGE :::::.: : .. ... .:. : :.::: :.::.. . . :: .:: :::: NP_001 EVAVKIID-KTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGE 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 LFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGL .:: . : : .:. :.:....: : : :.:::.: :::::: :.::.:::. NP_001 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGF 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 ATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQP .. : ..:. :. .::. ::.::::.. ... . ::::: :..: ....: ::.: NP_001 SNEFTFGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD-- 200 210 220 230 240 250 220 230 240 250 260 pF1KB5 SDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN----- ... .: . . : :. ... ::.:.:. ::: : :. .: ::::.: NP_001 GQNLKELRERVLRGKYRIPFY-MSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHED 260 270 280 290 300 310 270 280 290 300 310 pF1KB5 ---KPLKK---GAKRPRVTSGGVSESPSGFSKH-IQSNLDFSPVNSA-SSEENVKYSSSQ :: . : :: : :: :.... ::..: . : . .. . :.::. NP_001 DELKPYVEPLPDYKDPRRTELMVSM---GYTREEIQDSLVGQRYNEVMATYLLLGYKSSE 320 330 340 350 360 320 330 340 350 360 370 pF1KB5 PE-------PRTGLSLWDTS-PSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSSQNPW : :: . .: ..: :: :. ...: . : . ...: : ..: . NP_001 LEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSAN----PKQRRFSDQA-GPAIPTSNSY 370 380 390 400 410 420 380 390 400 410 pF1KB5 QRLVKRMTRFFTKLDADKSYQCLKETCEKL------GYQWKKSC----MNQVTISTTDR- .. .. . . . :. . :. : . ::. :.: ..:.: NP_001 SKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRS 430 440 450 460 470 480 420 430 440 450 460 470 pF1KB5 RNNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT ::. :. ...: NP_001 RNSPLLERASLGQASIQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTF 490 500 510 520 530 540 476 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:26:53 2016 done: Sat Nov 5 10:26:55 2016 Total Scan time: 7.920 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]