FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5825, 125 aa 1>>>pF1KB5825 125 - 125 aa - 125 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3194+/-0.000338; mu= 16.9086+/- 0.021 mean_var=98.1454+/-24.186, 0's: 0 Z-trim(115.3): 130 B-trim: 1550 in 1/51 Lambda= 0.129461 statistics sampled from 25478 (25641) to 25478 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.301), width: 16 Scan time: 4.150 The best scores are: opt bits E(85289) NP_057131 (OMIM: 607835) splicing factor 3B subuni ( 125) 833 165.0 2.8e-41 NP_001177938 (OMIM: 605221) serine/arginine-rich s ( 165) 166 40.6 0.001 NP_001287865 (OMIM: 605221) serine/arginine-rich s ( 172) 166 40.7 0.0011 NP_001177935 (OMIM: 605221) serine/arginine-rich s ( 173) 166 40.7 0.0011 NP_001177936 (OMIM: 605221) serine/arginine-rich s ( 182) 166 40.7 0.0011 NP_006616 (OMIM: 605221) serine/arginine-rich spli ( 183) 166 40.7 0.0011 NP_001287866 (OMIM: 605221) serine/arginine-rich s ( 217) 166 40.8 0.0012 NP_001177934 (OMIM: 605221) serine/arginine-rich s ( 261) 166 40.9 0.0013 NP_473357 (OMIM: 605221) serine/arginine-rich spli ( 262) 166 40.9 0.0013 XP_005250918 (OMIM: 604679) PREDICTED: polyadenyla ( 636) 156 39.6 0.008 NP_002559 (OMIM: 604679) polyadenylate-binding pro ( 636) 156 39.6 0.008 >>NP_057131 (OMIM: 607835) splicing factor 3B subunit 6 (125 aa) initn: 833 init1: 833 opt: 833 Z-score: 862.1 bits: 165.0 E(85289): 2.8e-41 Smith-Waterman score: 833; 100.0% identity (100.0% similar) in 125 aa overlap (1-125:1-125) 10 20 30 40 50 60 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 YVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGIN 70 80 90 100 110 120 pF1KB5 TDPPK ::::: NP_057 TDPPK >>NP_001177938 (OMIM: 605221) serine/arginine-rich splic (165 aa) initn: 141 init1: 84 opt: 166 Z-score: 187.6 bits: 40.6 E(85289): 0.001 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_001 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_001 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_001 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRKPNCSWNTQYSSAYYTSRKI 120 130 140 150 160 >>NP_001287865 (OMIM: 605221) serine/arginine-rich splic (172 aa) initn: 141 init1: 84 opt: 166 Z-score: 187.4 bits: 40.7 E(85289): 0.0011 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_001 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_001 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_001 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDSQVSKKKNE 120 130 140 150 160 170 >>NP_001177935 (OMIM: 605221) serine/arginine-rich splic (173 aa) initn: 141 init1: 84 opt: 166 Z-score: 187.4 bits: 40.7 E(85289): 0.0011 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_001 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_001 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_001 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDSQVSKKKN 120 130 140 150 160 170 >>NP_001177936 (OMIM: 605221) serine/arginine-rich splic (182 aa) initn: 141 init1: 84 opt: 166 Z-score: 187.2 bits: 40.7 E(85289): 0.0011 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_001 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_001 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_001 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDRPNCSWNTQ 120 130 140 150 160 170 >>NP_006616 (OMIM: 605221) serine/arginine-rich splicing (183 aa) initn: 141 init1: 84 opt: 166 Z-score: 187.2 bits: 40.7 E(85289): 0.0011 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_006 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_006 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_006 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRPNCSWNT 120 130 140 150 160 170 >>NP_001287866 (OMIM: 605221) serine/arginine-rich splic (217 aa) initn: 141 init1: 84 opt: 166 Z-score: 186.4 bits: 40.8 E(85289): 0.0012 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_001 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_001 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_001 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRS 120 130 140 150 160 170 >>NP_001177934 (OMIM: 605221) serine/arginine-rich splic (261 aa) initn: 157 init1: 84 opt: 166 Z-score: 185.6 bits: 40.9 E(85289): 0.0013 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_001 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_001 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_001 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPRRSRSHSDNDRFKHRNRSF 120 130 140 150 160 170 >>NP_473357 (OMIM: 605221) serine/arginine-rich splicing (262 aa) initn: 157 init1: 84 opt: 166 Z-score: 185.6 bits: 40.9 E(85289): 0.0013 Smith-Waterman score: 166; 33.7% identity (61.6% similar) in 86 aa overlap (14-96:7-90) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVG---NTPETR :: : :..::. .:.. ::.:::: .. : : . : NP_473 MSRYLRPP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKY : ::: .::. ::..: .:. .:.: . . . ...: NP_473 GFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYD 60 70 80 90 100 110 120 pF1KB5 GINTDPPK NP_473 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRS 120 130 140 150 160 170 >>XP_005250918 (OMIM: 604679) PREDICTED: polyadenylate-b (636 aa) initn: 110 init1: 87 opt: 156 Z-score: 171.6 bits: 39.6 E(85289): 0.008 Smith-Waterman score: 156; 26.9% identity (65.4% similar) in 104 aa overlap (21-120:193-295) 10 20 30 40 50 pF1KB5 MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRV .::.:. . :.. :.:::.:: ...: XP_005 LNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKV 170 180 190 200 210 220 60 70 80 90 100 pF1KB5 --GNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEE .. ...: ..: .: ::..: :...: .. .. . : ... .. . :.: : XP_005 MTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV-GRAQKKVERQTELKRKFE 230 240 250 260 270 280 110 120 pF1KB5 QLKLLK-EKY-GINTDPPK :.: . .: :.: XP_005 QMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFS 290 300 310 320 330 340 125 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:01:46 2016 done: Sat Nov 5 15:01:46 2016 Total Scan time: 4.150 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]