FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5829, 124 aa 1>>>pF1KB5829 124 - 124 aa - 124 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7761+/-0.000255; mu= 14.1590+/- 0.016 mean_var=65.2240+/-13.348, 0's: 0 Z-trim(120.7): 11 B-trim: 102 in 1/52 Lambda= 0.158807 statistics sampled from 36192 (36203) to 36192 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.424), width: 16 Scan time: 5.300 The best scores are: opt bits E(85289) XP_016873605 (OMIM: 605426) PREDICTED: p53-regulat ( 124) 817 194.6 3.3e-50 NP_071395 (OMIM: 605426) p53-regulated apoptosis-i ( 124) 817 194.6 3.3e-50 XP_016873602 (OMIM: 605426) PREDICTED: p53-regulat ( 146) 817 194.7 3.8e-50 NP_001182123 (OMIM: 605426) p53-regulated apoptosi ( 120) 773 184.5 3.5e-47 XP_016873603 (OMIM: 605426) PREDICTED: p53-regulat ( 142) 773 184.6 4e-47 NP_001182124 (OMIM: 605426) p53-regulated apoptosi ( 86) 573 138.6 1.7e-33 XP_016873606 (OMIM: 605426) PREDICTED: p53-regulat ( 108) 573 138.7 2e-33 NP_001238893 (OMIM: 605426) p53-regulated apoptosi ( 108) 337 84.6 3.8e-17 XP_016873604 (OMIM: 605426) PREDICTED: p53-regulat ( 130) 332 83.5 9.8e-17 >>XP_016873605 (OMIM: 605426) PREDICTED: p53-regulated a (124 aa) initn: 817 init1: 817 opt: 817 Z-score: 1022.3 bits: 194.6 E(85289): 3.3e-50 Smith-Waterman score: 817; 98.4% identity (98.4% similar) in 124 aa overlap (1-124:1-124) 10 20 30 40 50 60 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLGDRSLGSAFELSYDQKKAP ::::::::::::::::::::::::::::::::::::::::: :: ::::::::::::::: XP_016 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLRDRPLGSAFELSYDQKKAP 70 80 90 100 110 120 pF1KB5 LRLQ :::: XP_016 LRLQ >>NP_071395 (OMIM: 605426) p53-regulated apoptosis-induc (124 aa) initn: 817 init1: 817 opt: 817 Z-score: 1022.3 bits: 194.6 E(85289): 3.3e-50 Smith-Waterman score: 817; 98.4% identity (98.4% similar) in 124 aa overlap (1-124:1-124) 10 20 30 40 50 60 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLGDRSLGSAFELSYDQKKAP ::::::::::::::::::::::::::::::::::::::::: :: ::::::::::::::: NP_071 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLRDRPLGSAFELSYDQKKAP 70 80 90 100 110 120 pF1KB5 LRLQ :::: NP_071 LRLQ >>XP_016873602 (OMIM: 605426) PREDICTED: p53-regulated a (146 aa) initn: 817 init1: 817 opt: 817 Z-score: 1021.3 bits: 194.7 E(85289): 3.8e-50 Smith-Waterman score: 817; 98.4% identity (98.4% similar) in 124 aa overlap (1-124:23-146) 10 20 30 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG :::::::::::::::::::::::::::::::::::::: XP_016 MCRRRPFPRTLRLLGGRQGLPWMGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGA 70 80 90 100 110 120 100 110 120 pF1KB5 TVLGDRSLGSAFELSYDQKKAPLRLQ ::: :: ::::::::::::::::::: XP_016 TVLRDRPLGSAFELSYDQKKAPLRLQ 130 140 >>NP_001182123 (OMIM: 605426) p53-regulated apoptosis-in (120 aa) initn: 586 init1: 586 opt: 773 Z-score: 968.0 bits: 184.5 E(85289): 3.5e-47 Smith-Waterman score: 773; 95.2% identity (95.2% similar) in 124 aa overlap (1-124:1-120) 10 20 30 40 50 60 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLGDRSLGSAFELSYDQKKAP ::::::::::::::::::::::::: :::::::::::: :: ::::::::::::::: NP_001 GCRGIEALSVSSGSWSSATVWILTG----LSRPFLPGATVLRDRPLGSAFELSYDQKKAP 70 80 90 100 110 pF1KB5 LRLQ :::: NP_001 LRLQ 120 >>XP_016873603 (OMIM: 605426) PREDICTED: p53-regulated a (142 aa) initn: 586 init1: 586 opt: 773 Z-score: 967.0 bits: 184.6 E(85289): 4e-47 Smith-Waterman score: 773; 95.2% identity (95.2% similar) in 124 aa overlap (1-124:23-142) 10 20 30 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG :::::::::::::::::::::::::::::::::::::: XP_016 MCRRRPFPRTLRLLGGRQGLPWMGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGA ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_016 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTG----LSRPFLPGA 70 80 90 100 110 100 110 120 pF1KB5 TVLGDRSLGSAFELSYDQKKAPLRLQ ::: :: ::::::::::::::::::: XP_016 TVLRDRPLGSAFELSYDQKKAPLRLQ 120 130 140 >>NP_001182124 (OMIM: 605426) p53-regulated apoptosis-in (86 aa) initn: 573 init1: 573 opt: 573 Z-score: 722.3 bits: 138.6 E(85289): 1.7e-33 Smith-Waterman score: 573; 100.0% identity (100.0% similar) in 84 aa overlap (1-84:1-84) 10 20 30 40 50 60 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLGDRSLGSAFELSYDQKKAP :::::::::::::::::::::::: NP_001 GCRGIEALSVSSGSWSSATVWILTVQ 70 80 >>XP_016873606 (OMIM: 605426) PREDICTED: p53-regulated a (108 aa) initn: 573 init1: 573 opt: 573 Z-score: 721.0 bits: 138.7 E(85289): 2e-33 Smith-Waterman score: 573; 100.0% identity (100.0% similar) in 84 aa overlap (1-84:23-106) 10 20 30 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG :::::::::::::::::::::::::::::::::::::: XP_016 MCRRRPFPRTLRLLGGRQGLPWMGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGA :::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTVQ 70 80 90 100 100 110 120 pF1KB5 TVLGDRSLGSAFELSYDQKKAPLRLQ >>NP_001238893 (OMIM: 605426) p53-regulated apoptosis-in (108 aa) initn: 346 init1: 337 opt: 337 Z-score: 428.7 bits: 84.6 E(85289): 3.8e-17 Smith-Waterman score: 337; 100.0% identity (100.0% similar) in 49 aa overlap (1-49:1-49) 10 20 30 40 50 60 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSPCSENRDGLLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLGDRSLGSAFELSYDQKKAP NP_001 ATAPGRLCSHRGADIPSFQTHQDPVTASGSSELHADCPQFRALDRAGN 70 80 90 100 >>XP_016873604 (OMIM: 605426) PREDICTED: p53-regulated a (130 aa) initn: 338 init1: 328 opt: 332 Z-score: 421.5 bits: 83.5 E(85289): 9.8e-17 Smith-Waterman score: 332; 87.9% identity (91.4% similar) in 58 aa overlap (1-58:23-76) 10 20 30 pF1KB5 MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG :::::::::::::::::::::::::::::::::::::: XP_016 MCRRRPFPRTLRLLGGRQGLPWMGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 RAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGA :::::::::.. ::: : XP_016 RAQTHTPGWMG----LGAPVTYSKKSFPVANNEDDALGSLWALRRGSLLFLLSQFGFHGN 70 80 90 100 110 124 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:04:08 2016 done: Sat Nov 5 15:04:09 2016 Total Scan time: 5.300 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]