FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5830, 481 aa 1>>>pF1KB5830 481 - 481 aa - 481 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.5981+/-0.000653; mu= -3.1116+/- 0.038 mean_var=669.3333+/-156.670, 0's: 0 Z-trim(114.5): 1887 B-trim: 0 in 0/56 Lambda= 0.049574 statistics sampled from 21992 (24439) to 21992 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.287), width: 16 Scan time: 8.790 The best scores are: opt bits E(85289) XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 3247 248.7 2.8e-65 XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 3247 248.7 2.8e-65 NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 2812 217.4 6e-56 NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 2812 217.4 6e-56 XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 2717 210.8 7.1e-54 NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 2717 210.8 7.1e-54 NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 2717 210.8 7.1e-54 NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 2717 210.8 7.1e-54 XP_011524924 (OMIM: 125853,164731,240900) PREDICTE ( 400) 2638 205.0 3.3e-52 XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 2573 200.5 8.9e-51 NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 2573 200.5 8.9e-51 XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 2573 200.5 8.9e-51 NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 2474 193.4 1.2e-48 NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 2474 193.4 1.2e-48 XP_016876566 (OMIM: 114480,114500,164730,167000,17 ( 530) 2440 191.0 6.8e-48 XP_016876564 (OMIM: 114480,114500,164730,167000,17 ( 530) 2440 191.0 6.8e-48 XP_016876565 (OMIM: 114480,114500,164730,167000,17 ( 530) 2440 191.0 6.8e-48 XP_016876567 (OMIM: 114480,114500,164730,167000,17 ( 530) 2440 191.0 6.8e-48 XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 2305 181.2 5e-45 XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 2244 176.8 1e-43 NP_001317440 (OMIM: 125853,164731,240900) RAC-beta ( 438) 1852 148.8 2.8e-35 XP_011542315 (OMIM: 611223,615937) PREDICTED: RAC- ( 295) 1385 115.1 2.7e-25 XP_011542316 (OMIM: 611223,615937) PREDICTED: RAC- ( 249) 1199 101.7 2.5e-21 XP_006711789 (OMIM: 611223,615937) PREDICTED: RAC- ( 247) 1168 99.5 1.2e-20 NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 1128 96.9 1e-19 NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 1128 96.9 1e-19 NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 1128 97.0 1.1e-19 NP_997700 (OMIM: 176970) protein kinase C beta typ ( 671) 1119 96.7 2.1e-19 XP_011540074 (OMIM: 602549) PREDICTED: serine/thre ( 658) 1114 96.3 2.7e-19 NP_001307637 (OMIM: 602549) serine/threonine-prote ( 827) 1114 96.5 3e-19 XP_016857272 (OMIM: 602549) PREDICTED: serine/thre ( 920) 1114 96.6 3.1e-19 XP_016857271 (OMIM: 602549) PREDICTED: serine/thre ( 922) 1114 96.6 3.1e-19 NP_001307636 (OMIM: 602549) serine/threonine-prote ( 936) 1114 96.6 3.2e-19 NP_001307638 (OMIM: 602549) serine/threonine-prote ( 968) 1114 96.6 3.2e-19 NP_006247 (OMIM: 602549) serine/threonine-protein ( 984) 1114 96.7 3.2e-19 NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 1102 95.2 4e-19 NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 1102 95.2 4e-19 NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 1102 95.2 4.1e-19 XP_016876947 (OMIM: 601367,605437) PREDICTED: prot ( 522) 1102 95.3 4.3e-19 NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 1102 95.3 4.4e-19 XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 1102 95.3 4.4e-19 XP_011535257 (OMIM: 601367,605437) PREDICTED: prot ( 603) 1102 95.4 4.7e-19 XP_011535256 (OMIM: 601367,605437) PREDICTED: prot ( 604) 1102 95.4 4.7e-19 NP_006246 (OMIM: 601367,605437) protein kinase C e ( 683) 1102 95.5 4.9e-19 >>XP_011524916 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_011 E >>NP_001617 (OMIM: 125853,164731,240900) RAC-beta serine (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : NP_001 E >>XP_011524920 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_011 E >>XP_011524922 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_011 E >>XP_016881959 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_016 E >>XP_011524921 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_011 E >>XP_011524917 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_011 E >>XP_011524918 (OMIM: 125853,164731,240900) PREDICTED: R (481 aa) initn: 3247 init1: 3247 opt: 3247 Z-score: 1293.1 bits: 248.7 E(85289): 2.8e-65 Smith-Waterman score: 3247; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB5 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR 430 440 450 460 470 480 pF1KB5 E : XP_011 E >>NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ser (419 aa) initn: 2812 init1: 2812 opt: 2812 Z-score: 1125.5 bits: 217.4 E(85289): 6e-56 Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 419 aa overlap (63-481:1-419) 40 50 60 70 80 90 pF1KB5 GSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDS :::::::::::::::::::::::::::::: NP_001 MKTERPRPNTFVIRCLQWTTVIERTFHVDS 10 20 30 100 110 120 130 140 150 pF1KB5 PDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDF 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 DYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 TALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVV 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 YRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 WWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITP 340 350 360 370 380 390 460 470 480 pF1KB5 PDRYDSLGLLELDQRTHFPQFSYSASIRE ::::::::::::::::::::::::::::: NP_001 PDRYDSLGLLELDQRTHFPQFSYSASIRE 400 410 >>NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ser (419 aa) initn: 2812 init1: 2812 opt: 2812 Z-score: 1125.5 bits: 217.4 E(85289): 6e-56 Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 419 aa overlap (63-481:1-419) 40 50 60 70 80 90 pF1KB5 GSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDS :::::::::::::::::::::::::::::: NP_001 MKTERPRPNTFVIRCLQWTTVIERTFHVDS 10 20 30 100 110 120 130 140 150 pF1KB5 PDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDF 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 DYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 TALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVV 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 YRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 WWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB5 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITP 340 350 360 370 380 390 460 470 480 pF1KB5 PDRYDSLGLLELDQRTHFPQFSYSASIRE ::::::::::::::::::::::::::::: NP_001 PDRYDSLGLLELDQRTHFPQFSYSASIRE 400 410 481 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 23:19:26 2016 done: Sat Nov 5 23:19:27 2016 Total Scan time: 8.790 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]