FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5837, 240 aa 1>>>pF1KB5837 240 - 240 aa - 240 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.6527+/-0.000383; mu= -7.0729+/- 0.024 mean_var=424.5419+/-88.167, 0's: 0 Z-trim(125.8): 12 B-trim: 890 in 1/56 Lambda= 0.062246 statistics sampled from 50274 (50286) to 50274 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.841), E-opt: 0.2 (0.59), width: 16 Scan time: 7.180 The best scores are: opt bits E(85289) NP_057563 (OMIM: 607290) protein shisa-5 isoform a ( 240) 1744 169.4 4.9e-42 NP_001258994 (OMIM: 607290) protein shisa-5 isofor ( 233) 1669 162.7 5.1e-40 XP_011532098 (OMIM: 607290) PREDICTED: protein shi ( 209) 1533 150.4 2.3e-36 NP_001258995 (OMIM: 607290) protein shisa-5 isofor ( 209) 1533 150.4 2.3e-36 NP_001258997 (OMIM: 607290) protein shisa-5 isofor ( 209) 1533 150.4 2.3e-36 XP_006713251 (OMIM: 607290) PREDICTED: protein shi ( 209) 1533 150.4 2.3e-36 NP_001258996 (OMIM: 607290) protein shisa-5 isofor ( 209) 1533 150.4 2.3e-36 XP_005265262 (OMIM: 607290) PREDICTED: protein shi ( 209) 1533 150.4 2.3e-36 NP_001259011 (OMIM: 607290) protein shisa-5 isofor ( 137) 996 102.0 5.6e-22 NP_001259012 (OMIM: 607290) protein shisa-5 isofor ( 118) 819 86.0 3.1e-17 >>NP_057563 (OMIM: 607290) protein shisa-5 isoform a pre (240 aa) initn: 1744 init1: 1744 opt: 1744 Z-score: 875.6 bits: 169.4 E(85289): 4.9e-42 Smith-Waterman score: 1744; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240) 10 20 30 40 50 60 pF1KB5 MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VLKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VLKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 190 200 210 220 230 240 >>NP_001258994 (OMIM: 607290) protein shisa-5 isoform b (233 aa) initn: 1183 init1: 1183 opt: 1669 Z-score: 839.4 bits: 162.7 E(85289): 5.1e-40 Smith-Waterman score: 1669; 97.1% identity (97.1% similar) in 240 aa overlap (1-240:1-233) 10 20 30 40 50 60 pF1KB5 MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VLKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLS :::::::::: ::::::::::::::::::::::::::::::::::::::::::: NP_001 VLKKFVWSEE-------SVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLS 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 PPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 180 190 200 210 220 230 >>XP_011532098 (OMIM: 607290) PREDICTED: protein shisa-5 (209 aa) initn: 1533 init1: 1533 opt: 1533 Z-score: 773.9 bits: 150.4 E(85289): 2.3e-36 Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 209 aa overlap (32-240:1-209) 10 20 30 40 50 60 pF1KB5 TAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDV :::::::::::::::::::::::::::::: XP_011 MASRGLSLFPESCPDFCCGTCDDQYCCSDV 10 20 30 70 80 90 100 110 120 pF1KB5 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 160 170 180 190 200 >>NP_001258995 (OMIM: 607290) protein shisa-5 isoform c (209 aa) initn: 1533 init1: 1533 opt: 1533 Z-score: 773.9 bits: 150.4 E(85289): 2.3e-36 Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 209 aa overlap (32-240:1-209) 10 20 30 40 50 60 pF1KB5 TAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDV :::::::::::::::::::::::::::::: NP_001 MASRGLSLFPESCPDFCCGTCDDQYCCSDV 10 20 30 70 80 90 100 110 120 pF1KB5 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 160 170 180 190 200 >>NP_001258997 (OMIM: 607290) protein shisa-5 isoform c (209 aa) initn: 1533 init1: 1533 opt: 1533 Z-score: 773.9 bits: 150.4 E(85289): 2.3e-36 Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 209 aa overlap (32-240:1-209) 10 20 30 40 50 60 pF1KB5 TAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDV :::::::::::::::::::::::::::::: NP_001 MASRGLSLFPESCPDFCCGTCDDQYCCSDV 10 20 30 70 80 90 100 110 120 pF1KB5 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 160 170 180 190 200 >>XP_006713251 (OMIM: 607290) PREDICTED: protein shisa-5 (209 aa) initn: 1533 init1: 1533 opt: 1533 Z-score: 773.9 bits: 150.4 E(85289): 2.3e-36 Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 209 aa overlap (32-240:1-209) 10 20 30 40 50 60 pF1KB5 TAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDV :::::::::::::::::::::::::::::: XP_006 MASRGLSLFPESCPDFCCGTCDDQYCCSDV 10 20 30 70 80 90 100 110 120 pF1KB5 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 160 170 180 190 200 >>NP_001258996 (OMIM: 607290) protein shisa-5 isoform c (209 aa) initn: 1533 init1: 1533 opt: 1533 Z-score: 773.9 bits: 150.4 E(85289): 2.3e-36 Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 209 aa overlap (32-240:1-209) 10 20 30 40 50 60 pF1KB5 TAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDV :::::::::::::::::::::::::::::: NP_001 MASRGLSLFPESCPDFCCGTCDDQYCCSDV 10 20 30 70 80 90 100 110 120 pF1KB5 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 160 170 180 190 200 >>XP_005265262 (OMIM: 607290) PREDICTED: protein shisa-5 (209 aa) initn: 1533 init1: 1533 opt: 1533 Z-score: 773.9 bits: 150.4 E(85289): 2.3e-36 Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 209 aa overlap (32-240:1-209) 10 20 30 40 50 60 pF1KB5 TAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESCPDFCCGTCDDQYCCSDV :::::::::::::::::::::::::::::: XP_005 MASRGLSLFPESCPDFCCGTCDDQYCCSDV 10 20 30 70 80 90 100 110 120 pF1KB5 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 160 170 180 190 200 >>NP_001259011 (OMIM: 607290) protein shisa-5 isoform d (137 aa) initn: 996 init1: 996 opt: 996 Z-score: 515.5 bits: 102.0 E(85289): 5.6e-22 Smith-Waterman score: 996; 100.0% identity (100.0% similar) in 136 aa overlap (105-240:2-137) 80 90 100 110 120 130 pF1KB5 PEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSVVTIIICFTCSCCC :::::::::::::::::::::::::::::: NP_001 MGFGATLAVGLTIFVLSVVTIIICFTCSCCC 10 20 30 140 150 160 170 180 190 pF1KB5 LYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQ 40 50 60 70 80 90 200 210 220 230 240 pF1KB5 YPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL :::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL 100 110 120 130 >>NP_001259012 (OMIM: 607290) protein shisa-5 isoform e (118 aa) initn: 819 init1: 819 opt: 819 Z-score: 430.4 bits: 86.0 E(85289): 3.1e-17 Smith-Waterman score: 819; 100.0% identity (100.0% similar) in 111 aa overlap (105-215:2-112) 80 90 100 110 120 130 pF1KB5 PEASVPASVEPVEQLGSALRFRPGYNDPMSGFGATLAVGLTIFVLSVVTIIICFTCSCCC :::::::::::::::::::::::::::::: NP_001 MGFGATLAVGLTIFVLSVVTIIICFTCSCCC 10 20 30 140 150 160 170 180 190 pF1KB5 LYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYKTCRRPRPVVTTTTSTTVVHAPYPQPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQ 40 50 60 70 80 90 200 210 220 230 240 pF1KB5 YPPPYPAQPMGPPAYHETLAGGAAAPYPASQPPYNPAYMDAPKAAL ::::::::::::::::::::: NP_001 YPPPYPAQPMGPPAYHETLAGECPCQL 100 110 240 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:28:14 2016 done: Sat Nov 5 10:28:15 2016 Total Scan time: 7.180 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]