FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5839, 203 aa 1>>>pF1KB5839 203 - 203 aa - 203 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0305+/-0.00034; mu= 14.9717+/- 0.021 mean_var=64.3221+/-12.666, 0's: 0 Z-trim(114.7): 7 B-trim: 174 in 1/57 Lambda= 0.159917 statistics sampled from 24757 (24764) to 24757 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.29), width: 16 Scan time: 5.980 The best scores are: opt bits E(85289) NP_056263 (OMIM: 616467) protein DPCD isoform 2 [H ( 203) 1356 321.2 7.3e-88 NP_001316672 (OMIM: 616467) protein DPCD isoform 3 ( 191) 909 218.0 7.7e-57 NP_001316673 (OMIM: 616467) protein DPCD isoform 4 ( 170) 907 217.5 9.7e-57 NP_001316671 (OMIM: 616467) protein DPCD isoform 1 ( 214) 757 183.0 3e-46 NP_001316674 (OMIM: 616467) protein DPCD isoform 5 ( 114) 452 112.4 2.8e-25 NP_001316675 (OMIM: 616467) protein DPCD isoform 6 ( 63) 315 80.7 5.7e-16 >>NP_056263 (OMIM: 616467) protein DPCD isoform 2 [Homo (203 aa) initn: 1356 init1: 1356 opt: 1356 Z-score: 1698.4 bits: 321.2 E(85289): 7.3e-88 Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203) 10 20 30 40 50 60 pF1KB5 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIISYQKPKEVVVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIISYQKPKEVVVAE 130 140 150 160 170 180 190 200 pF1KB5 SELQKELKKVKTAHSNDGDCKTQ ::::::::::::::::::::::: NP_056 SELQKELKKVKTAHSNDGDCKTQ 190 200 >>NP_001316672 (OMIM: 616467) protein DPCD isoform 3 [Ho (191 aa) initn: 925 init1: 909 opt: 909 Z-score: 1141.4 bits: 218.0 E(85289): 7.7e-57 Smith-Waterman score: 1238; 94.1% identity (94.1% similar) in 203 aa overlap (1-203:1-191) 10 20 30 40 50 60 pF1KB5 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIISYQKPKEVVVAE ::::::::::::::: ::::::::::::::::::::::::::::::::: NP_001 DQKERCIIVRTTNKK------------HQLPLDDALLSFAHANCTLIISYQKPKEVVVAE 130 140 150 160 190 200 pF1KB5 SELQKELKKVKTAHSNDGDCKTQ ::::::::::::::::::::::: NP_001 SELQKELKKVKTAHSNDGDCKTQ 170 180 190 >>NP_001316673 (OMIM: 616467) protein DPCD isoform 4 [Ho (170 aa) initn: 907 init1: 907 opt: 907 Z-score: 1139.7 bits: 217.5 E(85289): 9.7e-57 Smith-Waterman score: 907; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:1-135) 10 20 30 40 50 60 pF1KB5 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIISYQKPKEVVVAE ::::::::::::::: NP_001 DQKERCIIVRTTNKKRTGWRLLWTPLAMRCAGVHGTPSEIDTSYLWMTPC 130 140 150 160 170 >>NP_001316671 (OMIM: 616467) protein DPCD isoform 1 [Ho (214 aa) initn: 1342 init1: 757 opt: 757 Z-score: 951.2 bits: 183.0 E(85289): 3e-46 Smith-Waterman score: 1324; 94.9% identity (94.9% similar) in 214 aa overlap (1-203:1-214) 10 20 30 40 50 60 pF1KB5 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA 10 20 30 40 50 60 70 80 90 100 pF1KB5 MGQWQLEVGDPAPLGAGNLGPELIKESNAN-----------PIFMRKDTKMSFQWRIRNL :::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 MGQWQLEVGDPAPLGAGNLGPELIKESNANEQSSSWICLLQPIFMRKDTKMSFQWRIRNL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 PYPKDVYSVSVDQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYPKDVYSVSVDQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANCTLIIS 130 140 150 160 170 180 170 180 190 200 pF1KB5 YQKPKEVVVAESELQKELKKVKTAHSNDGDCKTQ :::::::::::::::::::::::::::::::::: NP_001 YQKPKEVVVAESELQKELKKVKTAHSNDGDCKTQ 190 200 210 >>NP_001316674 (OMIM: 616467) protein DPCD isoform 5 [Ho (114 aa) initn: 452 init1: 452 opt: 452 Z-score: 574.9 bits: 112.4 E(85289): 2.8e-25 Smith-Waterman score: 452; 98.6% identity (100.0% similar) in 69 aa overlap (135-203:46-114) 110 120 130 140 150 160 pF1KB5 RIRNLPYPKDVYSVSVDQKERCIIVRTTNKKYYKKFSIPDLDRHQLPLDDALLSFAHANC .::::::::::::::::::::::::::::: NP_001 SEQPTRSGLVGGFSGPLWPCGVQVCMAPPLRYYKKFSIPDLDRHQLPLDDALLSFAHANC 20 30 40 50 60 70 170 180 190 200 pF1KB5 TLIISYQKPKEVVVAESELQKELKKVKTAHSNDGDCKTQ ::::::::::::::::::::::::::::::::::::::: NP_001 TLIISYQKPKEVVVAESELQKELKKVKTAHSNDGDCKTQ 80 90 100 110 >>NP_001316675 (OMIM: 616467) protein DPCD isoform 6 [Ho (63 aa) initn: 315 init1: 315 opt: 315 Z-score: 407.7 bits: 80.7 E(85289): 5.7e-16 Smith-Waterman score: 315; 98.0% identity (98.0% similar) in 50 aa overlap (1-50:1-50) 10 20 30 40 50 60 pF1KB5 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLVRKWRVKSALGA :::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 MAVTGWLESLRTAQKTALLQDGRRKVHYLFPDGKEMAEEYDEKTSELLERPECGLMGRQE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MGQWQLEVGDPAPLGAGNLGPELIKESNANPIFMRKDTKMSFQWRIRNLPYPKDVYSVSV NP_001 DLT 203 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:07:38 2016 done: Sat Nov 5 15:07:39 2016 Total Scan time: 5.980 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]