FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5852, 469 aa 1>>>pF1KB5852 469 - 469 aa - 469 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2491+/-0.000809; mu= 14.3117+/- 0.049 mean_var=94.7303+/-19.321, 0's: 0 Z-trim(108.8): 53 B-trim: 56 in 1/51 Lambda= 0.131774 statistics sampled from 10407 (10460) to 10407 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.321), width: 16 Scan time: 2.990 The best scores are: opt bits E(32554) CCDS60458.1 RGS7 gene_id:6000|Hs108|chr1 ( 469) 3168 612.5 3.1e-175 CCDS60459.1 RGS7 gene_id:6000|Hs108|chr1 ( 477) 3090 597.6 9.1e-171 CCDS31071.1 RGS7 gene_id:6000|Hs108|chr1 ( 487) 3082 596.1 2.6e-170 CCDS9808.1 RGS6 gene_id:9628|Hs108|chr14 ( 472) 2429 472.0 6e-133 CCDS55924.1 RGS6 gene_id:9628|Hs108|chr14 ( 490) 2380 462.7 4e-130 CCDS73655.1 RGS6 gene_id:9628|Hs108|chr14 ( 437) 2327 452.6 3.9e-127 CCDS60457.1 RGS7 gene_id:6000|Hs108|chr1 ( 424) 2215 431.3 9.8e-121 CCDS10403.1 RGS11 gene_id:8786|Hs108|chr16 ( 446) 600 124.2 2.7e-28 CCDS66884.1 RGS11 gene_id:8786|Hs108|chr16 ( 456) 600 124.2 2.8e-28 CCDS42088.1 RGS11 gene_id:8786|Hs108|chr16 ( 467) 600 124.3 2.8e-28 CCDS45764.1 RGS9 gene_id:8787|Hs108|chr17 ( 671) 586 121.7 2.4e-27 CCDS42373.1 RGS9 gene_id:8787|Hs108|chr17 ( 674) 580 120.5 5.3e-27 CCDS6156.1 RGS20 gene_id:8601|Hs108|chr8 ( 241) 373 80.9 1.6e-15 CCDS69482.1 RGS20 gene_id:8601|Hs108|chr8 ( 273) 373 81.0 1.8e-15 CCDS6155.1 RGS20 gene_id:8601|Hs108|chr8 ( 388) 373 81.1 2.4e-15 CCDS5244.1 RGS17 gene_id:26575|Hs108|chr6 ( 210) 354 77.3 1.7e-14 CCDS41448.1 RGS21 gene_id:431704|Hs108|chr1 ( 152) 341 74.7 7.4e-14 CCDS13555.1 RGS19 gene_id:10287|Hs108|chr20 ( 217) 342 75.0 8.7e-14 CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 ( 180) 339 74.4 1.1e-13 CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 ( 198) 339 74.4 1.2e-13 CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 ( 181) 336 73.8 1.7e-13 CCDS35114.1 RGS3 gene_id:5998|Hs108|chr9 ( 311) 337 74.2 2.3e-13 CCDS1375.2 RGS1 gene_id:5996|Hs108|chr1 ( 209) 334 73.5 2.4e-13 CCDS1374.1 RGS18 gene_id:64407|Hs108|chr1 ( 235) 334 73.5 2.7e-13 CCDS6798.1 RGS3 gene_id:5998|Hs108|chr9 ( 519) 337 74.3 3.4e-13 CCDS1377.1 RGS2 gene_id:5997|Hs108|chr1 ( 211) 331 72.9 3.6e-13 CCDS65111.1 RGS3 gene_id:5998|Hs108|chr9 ( 591) 337 74.3 3.8e-13 CCDS6797.1 RGS3 gene_id:5998|Hs108|chr9 ( 917) 337 74.4 5.5e-13 CCDS43869.1 RGS3 gene_id:5998|Hs108|chr9 (1198) 337 74.5 6.9e-13 CCDS3367.1 RGS12 gene_id:6002|Hs108|chr4 (1376) 336 74.3 8.8e-13 CCDS3366.1 RGS12 gene_id:6002|Hs108|chr4 (1447) 336 74.4 9.2e-13 CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 ( 185) 318 70.4 1.8e-12 CCDS3368.1 RGS12 gene_id:6002|Hs108|chr4 ( 799) 324 71.9 2.7e-12 CCDS1348.1 RGS16 gene_id:6004|Hs108|chr1 ( 202) 315 69.9 2.9e-12 CCDS44272.1 RGS4 gene_id:5999|Hs108|chr1 ( 187) 312 69.3 4e-12 CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 ( 205) 312 69.3 4.3e-12 CCDS44270.1 RGS4 gene_id:5999|Hs108|chr1 ( 302) 312 69.4 6e-12 CCDS43405.1 RGS14 gene_id:10636|Hs108|chr5 ( 566) 310 69.2 1.3e-11 CCDS1376.1 RGS13 gene_id:6003|Hs108|chr1 ( 159) 297 66.4 2.5e-11 CCDS31294.1 RGS10 gene_id:6001|Hs108|chr10 ( 181) 292 65.5 5.4e-11 CCDS41572.1 RGS10 gene_id:6001|Hs108|chr10 ( 167) 289 64.9 7.6e-11 >>CCDS60458.1 RGS7 gene_id:6000|Hs108|chr1 (469 aa) initn: 3168 init1: 3168 opt: 3168 Z-score: 3259.6 bits: 612.5 E(32554): 3.1e-175 Smith-Waterman score: 3168; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE 370 380 390 400 410 420 430 440 450 460 pF1KB5 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY 430 440 450 460 >>CCDS60459.1 RGS7 gene_id:6000|Hs108|chr1 (477 aa) initn: 3144 init1: 3090 opt: 3090 Z-score: 3179.3 bits: 597.6 E(32554): 9.1e-171 Smith-Waterman score: 3090; 99.3% identity (100.0% similar) in 457 aa overlap (1-457:1-457) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE 370 380 390 400 410 420 430 440 450 460 pF1KB5 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ::::::::::::::::::::::::::::::::::... CCDS60 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGRNIPIFPCHKNCTPTLRASTNLL 430 440 450 460 470 >>CCDS31071.1 RGS7 gene_id:6000|Hs108|chr1 (487 aa) initn: 3076 init1: 3076 opt: 3082 Z-score: 3171.0 bits: 596.1 E(32554): 2.6e-170 Smith-Waterman score: 3122; 96.3% identity (96.3% similar) in 487 aa overlap (1-469:1-487) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE 370 380 390 400 410 420 430 440 450 460 pF1KB5 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKK------------------GKSLTSKRL ::::::::::::::::::::::::::::::::: ::::::::: CCDS31 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGKSLTSKRL 430 440 450 460 470 480 pF1KB5 TSLAQSY ::::::: CCDS31 TSLAQSY >>CCDS9808.1 RGS6 gene_id:9628|Hs108|chr14 (472 aa) initn: 2317 init1: 2317 opt: 2429 Z-score: 2500.3 bits: 472.0 E(32554): 6e-133 Smith-Waterman score: 2429; 73.5% identity (92.2% similar) in 472 aa overlap (1-468:1-471) 10 20 30 40 50 pF1KB5 MAQGNNYGQTSNGVADE---SPNMLVYRKMEDVIARMQDEKNG-IPIRTVKSFLSKIPSV ::::.. : . :::: ::::.:: :.::.:..:::.:.: .::::::::::::::: CCDS98 MAQGSG-DQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 FSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFW .:.::::::.:::.:::::::.:::.:.::.::.:::::::::.::::::::::.:::: CCDS98 VTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 PSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAK :::::::::::::.:::::::::::::::::::::.::::::::::::::::::::::.: CCDS98 PSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQND .:.:.:: :::::::::::::::::::::::::::.::.: :..::.:..:::::. .. CCDS98 IDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTEE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 IRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPF ...::.:. . . :......:: . . :.::: :::::::.::..:::::.::::. CCDS98 SQAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 LLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFS . : .:::::.:::...:..: ::::::::::::::..:: ::: :::.:::.::::::: CCDS98 ITPAEPSNPWISDDVALWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 SENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGR ::::::::::.::::.:...: .::.:::::::::::::::::::.::. :.::::. :: CCDS98 SENLRFWLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGR 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 YTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ::::::::::::::::::: ::.::.:::.:: ::::::::..::::.: :: CCDS98 YTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS 420 430 440 450 460 470 >>CCDS55924.1 RGS6 gene_id:9628|Hs108|chr14 (490 aa) initn: 2418 init1: 2245 opt: 2380 Z-score: 2449.7 bits: 462.7 E(32554): 4e-130 Smith-Waterman score: 2383; 70.8% identity (88.8% similar) in 490 aa overlap (1-468:1-489) 10 20 30 40 50 pF1KB5 MAQGNNYGQTSNGVADE---SPNMLVYRKMEDVIARMQDEKNG-IPIRTVKSFLSKIPSV ::::.. : . :::: ::::.:: :.::.:..:::.:.: .::::::::::::::: CCDS55 MAQGSG-DQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 FSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFW .:.::::::.:::.:::::::.:::.:.::.::.:::::::::.::::::::::.:::: CCDS55 VTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 PSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAK :::::::::::::.:::::::::::::::::::::.::::::::::::::::::::::.: CCDS55 PSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQND .:.:.:: :::::::::::::::::::::::::::.::.: :..::.:..:::::. .. CCDS55 IDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTEE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 IRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPF ...::.:. . . :......:: . . :.::: :::::::.::..:::::.::::. CCDS55 SQAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 LLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFS . : .:::::.:::...:..: ::::::::::::::..:: ::: :::.:::.::::::: CCDS55 ITPAEPSNPWISDDVALWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 SENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGR ::::::::::.::::.:...: .::.:::::::::::::::::::.::. :.::::. :: CCDS55 SENLRFWLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGR 360 370 380 390 400 410 420 430 440 450 pF1KB5 YTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKK------------------GKSLT ::::::::::::::::::: ::.::.:::.:: :::: ::::. CCDS55 YTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVGKSLA 420 430 440 450 460 470 460 pF1KB5 SKRLTSLAQSY .::::.: :: CCDS55 GKRLTGLMQSS 480 490 >>CCDS73655.1 RGS6 gene_id:9628|Hs108|chr14 (437 aa) initn: 2317 init1: 2317 opt: 2327 Z-score: 2396.0 bits: 452.6 E(32554): 3.9e-127 Smith-Waterman score: 2327; 75.2% identity (93.6% similar) in 436 aa overlap (34-468:1-436) 10 20 30 40 50 60 pF1KB5 GNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNG-IPIRTVKSFLSKIPSVFSGSDI :::.:.: .::::::::::::::: .:.:: CCDS73 MQDDKTGGVPIRTVKSFLSKIPSVVTGTDI 10 20 30 70 80 90 100 110 120 pF1KB5 VQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWE ::::.:::.:::::::.:::.:.::.::.:::::::::.::::::::::.:::::::::: CCDS73 VQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 PENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRD :::::::.:::::::::::::::::::::.::::::::::::::::::::::.:.:.:.: CCDS73 PENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 KIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSP : :::::::::::::::::::::::::::.::.: :..::.:..:::::. .. ...:: CCDS73 KTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTEESQAQSP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 THTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDP .:. . . :......:: . . :.::: :::::::.::..:::::.::::.. : .: CCDS73 VHVLSQPIRKTTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLITPAEP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 SNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRF ::::.:::...:..: ::::::::::::::..:: ::: :::.:::.::::::::::::: CCDS73 SNPWISDDVALWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRF 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 WLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDA ::::.::::.:...: .::.:::::::::::::::::::.::. :.::::. :::::::: CCDS73 WLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDA 340 350 360 370 380 390 430 440 450 460 pF1KB5 QEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ::::::::::::: ::.::.:::.:: ::::::::..::::.: :: CCDS73 QEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS 400 410 420 430 >>CCDS60457.1 RGS7 gene_id:6000|Hs108|chr1 (424 aa) initn: 2712 init1: 2210 opt: 2215 Z-score: 2281.1 bits: 431.3 E(32554): 9.8e-121 Smith-Waterman score: 2584; 87.7% identity (88.4% similar) in 457 aa overlap (1-457:1-404) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC ::::::::::::::: CCDS60 DIVQWLIKNLTIEDP--------------------------------------------- 70 130 140 150 160 170 180 pF1KB5 WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 --------AVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK 80 90 100 110 120 190 200 210 220 230 240 pF1KB5 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB5 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB5 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB5 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE 310 320 330 340 350 360 430 440 450 460 pF1KB5 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ::::::::::::::::::::::::::::::::::... CCDS60 DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGRNIPIFPCHKNCTPTLRASTNLL 370 380 390 400 410 420 >>CCDS10403.1 RGS11 gene_id:8786|Hs108|chr16 (446 aa) initn: 793 init1: 464 opt: 600 Z-score: 621.4 bits: 124.2 E(32554): 2.7e-28 Smith-Waterman score: 1040; 37.9% identity (66.2% similar) in 438 aa overlap (27-461:1-408) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :: :.. ::: .:. .:. . ... :: . .:: CCDS10 MERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGS 10 20 30 70 80 90 100 110 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISD-HVLTLKDDGTFYRFQTPYFWPSN :.:::: ... . . ::::::.... :::..:. : . : :. : : ::::::::: :. CCDS10 DVVQWLAQKFCVSEE-EALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTST 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 CWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDK . :::.:: :... . : :.::: . ::.. . . :....:::. : .. : CCDS10 LRPAAELDYAIYLAKKNI--RKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAK 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB5 KRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRS .:.: .: .. ::...: :.:: :: .. : ..: . CCDS10 QRSKGDRLVIACQEQTYWLVNRPPPGAPDVLE---------QGPGRG------------- 160 170 180 240 250 260 270 280 290 pF1KB5 HSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP : . . . :: . : ...:.:.. : : :.: : .. ::. : .::.. CCDS10 -SCAASRVLMTK--SADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSG 190 200 210 220 230 240 300 310 320 330 340 350 pF1KB5 PDPSNPWLSDDTTFWELEASK--EPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSS :::::.::. ..: ..: :.. ::.::::.. : :.::::: .:. :: .:::. CCDS10 CLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSG 250 260 270 280 290 300 360 370 380 390 400 410 pF1KB5 ENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRY ::: :: : :.:. .::. :. ....:::::: .:.::.....: .....: :: CCDS10 ENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRY 310 320 330 340 350 360 420 430 440 450 460 pF1KB5 TFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ...::: ::: :::.::::::..:. :. :: . : : :: CCDS10 VLDDAQLHIYMLMKKDSYPRFLKSDMYKALL--AEAGIPLEMKRRVFPFTWRPRHSSPSP 370 380 390 400 410 420 CCDS10 ALLPTPVEPTAACGPGGGDGVA 430 440 >>CCDS66884.1 RGS11 gene_id:8786|Hs108|chr16 (456 aa) initn: 875 init1: 464 opt: 600 Z-score: 621.3 bits: 124.2 E(32554): 2.8e-28 Smith-Waterman score: 955; 36.4% identity (64.3% similar) in 440 aa overlap (25-461:20-418) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :::: :.. ::: .:. .:. . ... :: . .:: CCDS66 MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGS 10 20 30 40 50 70 80 90 100 110 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISD-HVLTLKDDGTFYRFQTPYFWPSN :.:::: ... . . ::::::.... :::..:. : . : :. : : ::::. CCDS66 DVVQWLAQKFCVSEE-EALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQVRL----- 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 CWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDK :.:: :... . : :.::: . ::.. . . :....:::. : .. : CCDS66 ------GGAAIYLAKKNI--RKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 KRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRS .:.: .: .. ::...: :.:: :: .. : ..: . CCDS66 QRSKGDRLVIACQEQTYWLVNRPPPGAPDVLE---------QGPGRG------------- 170 180 190 240 250 260 270 280 290 pF1KB5 HSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP : . . . :: . : ...:.:.. : : :.: : .. ::. : .::.. CCDS66 -SCAASRVLMTK--SADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSG 200 210 220 230 240 250 300 310 320 330 340 350 pF1KB5 PDPSNPWLSDDTTFWELEASK--EPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSS :::::.::. ..: ..: :.. ::.::::.. : :.::::: .:. :: .:::. CCDS66 CLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSG 260 270 280 290 300 310 360 370 380 390 400 410 pF1KB5 ENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRY ::: :: : :.:. .::. :. ....:::::: .:.::.....: .....: :: CCDS66 ENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRY 320 330 340 350 360 370 420 430 440 450 460 pF1KB5 TFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ...::: ::: :::.::::::..:. :. :: . : : :: CCDS66 VLDDAQLHIYMLMKKDSYPRFLKSDMYKALL--AEAGIPLEMKRRVFPFTWRPRHSSPSP 380 390 400 410 420 430 CCDS66 ALLPTPVEPTAACGPGGGDGVA 440 450 >>CCDS42088.1 RGS11 gene_id:8786|Hs108|chr16 (467 aa) initn: 806 init1: 464 opt: 600 Z-score: 621.1 bits: 124.3 E(32554): 2.8e-28 Smith-Waterman score: 1053; 38.2% identity (66.4% similar) in 440 aa overlap (25-461:20-429) 10 20 30 40 50 60 pF1KB5 MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS :::: :.. ::: .:. .:. . ... :: . .:: CCDS42 MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGS 10 20 30 40 50 70 80 90 100 110 pF1KB5 DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISD-HVLTLKDDGTFYRFQTPYFWPSN :.:::: ... . . ::::::.... :::..:. : . : :. : : ::::::::: :. CCDS42 DVVQWLAQKFCVSEE-EALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTST 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 CWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDK . :::.:: :... . : :.::: . ::.. . . :....:::. : .. : CCDS42 LRPAAELDYAIYLAKKNI--RKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRS .:.: .: .. ::...: :.:: :: .. : ..: . CCDS42 QRSKGDRLVIACQEQTYWLVNRPPPGAPDVLE---------QGPGRG------------- 180 190 200 210 240 250 260 270 280 290 pF1KB5 HSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP : . . . :: . : ...:.:.. : : :.: : .. ::. : .::.. CCDS42 -SCAASRVLMTK--SADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSG 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 PDPSNPWLSDDTTFWELEASK--EPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSS :::::.::. ..: ..: :.. ::.::::.. : :.::::: .:. :: .:::. CCDS42 CLPSNPWISDNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSG 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 ENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRY ::: :: : :.:. .::. :. ....:::::: .:.::.....: .....: :: CCDS42 ENLSFWEACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRY 330 340 350 360 370 380 420 430 440 450 460 pF1KB5 TFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKGKSLTSKRLTSLAQSY ...::: ::: :::.::::::..:. :. :: . : : :: CCDS42 VLDDAQLHIYMLMKKDSYPRFLKSDMYKALL--AEAGIPLEMKRRVFPFTWRPRHSSPSP 390 400 410 420 430 440 CCDS42 ALLPTPVEPTAACGPGGGDGVA 450 460 469 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:29:59 2016 done: Sat Nov 5 10:30:00 2016 Total Scan time: 2.990 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]