FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5853, 322 aa 1>>>pF1KB5853 322 - 322 aa - 322 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3916+/-0.000395; mu= 21.5678+/- 0.024 mean_var=74.3003+/-15.849, 0's: 0 Z-trim(111.8): 145 B-trim: 41 in 2/53 Lambda= 0.148792 statistics sampled from 20363 (20532) to 20363 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.241), width: 16 Scan time: 6.360 The best scores are: opt bits E(85289) NP_775857 (OMIM: 611698) solute carrier family 22 ( 322) 2180 477.4 1.7e-134 NP_001129978 (OMIM: 611698) solute carrier family ( 552) 1885 414.4 2.8e-115 XP_016872648 (OMIM: 607579) PREDICTED: solute carr ( 445) 1222 272.0 1.7e-72 NP_543142 (OMIM: 607579) solute carrier family 22 ( 553) 1222 272.1 1.9e-72 NP_955384 (OMIM: 610792) solute carrier family 22 ( 547) 1217 271.0 4e-72 XP_016873176 (OMIM: 610792) PREDICTED: solute carr ( 547) 1217 271.0 4e-72 XP_016873191 (OMIM: 607580) PREDICTED: solute carr ( 365) 1195 266.1 8.1e-71 XP_016873190 (OMIM: 607580) PREDICTED: solute carr ( 424) 1195 266.1 9e-71 XP_011543318 (OMIM: 607580) PREDICTED: solute carr ( 541) 1195 266.3 1e-70 NP_001034841 (OMIM: 607580) solute carrier family ( 541) 1195 266.3 1e-70 XP_011543269 (OMIM: 611698) PREDICTED: solute carr ( 187) 1166 259.5 3.9e-69 XP_016873188 (OMIM: 607580) PREDICTED: solute carr ( 489) 996 223.5 7.1e-58 NP_653186 (OMIM: 220150,607096) solute carrier fam ( 553) 929 209.2 1.6e-53 NP_001294914 (OMIM: 607097) solute carrier family ( 442) 926 208.4 2.2e-53 NP_060954 (OMIM: 607097) solute carrier family 22 ( 550) 926 208.5 2.6e-53 XP_016873184 (OMIM: 610792) PREDICTED: solute carr ( 372) 854 192.9 8.9e-49 XP_016873174 (OMIM: 610792) PREDICTED: solute carr ( 577) 854 193.1 1.2e-48 XP_016873175 (OMIM: 610792) PREDICTED: solute carr ( 577) 854 193.1 1.2e-48 XP_016873173 (OMIM: 610792) PREDICTED: solute carr ( 577) 854 193.1 1.2e-48 XP_016873193 (OMIM: 607580) PREDICTED: solute carr ( 316) 795 180.1 5.2e-45 XP_016873189 (OMIM: 607580) PREDICTED: solute carr ( 433) 795 180.3 6.4e-45 XP_006718493 (OMIM: 220150,607096) PREDICTED: solu ( 578) 781 177.4 6.2e-44 XP_006718494 (OMIM: 220150,607096) PREDICTED: solu ( 543) 703 160.6 6.5e-39 NP_695009 (OMIM: 607582) solute carrier family 22 ( 506) 695 158.9 2.1e-38 NP_695010 (OMIM: 607582) solute carrier family 22 ( 519) 695 158.9 2.1e-38 NP_695008 (OMIM: 607582) solute carrier family 22 ( 550) 695 158.9 2.2e-38 XP_016874051 (OMIM: 607582) PREDICTED: solute carr ( 551) 695 158.9 2.2e-38 NP_004781 (OMIM: 607582) solute carrier family 22 ( 563) 695 158.9 2.2e-38 NP_001263255 (OMIM: 220150,607096) solute carrier ( 519) 664 152.2 2.1e-36 NP_004245 (OMIM: 607581) solute carrier family 22 ( 542) 659 151.2 4.5e-36 NP_001171661 (OMIM: 607581) solute carrier family ( 542) 659 151.2 4.5e-36 NP_001263256 (OMIM: 220150,607096) solute carrier ( 445) 618 142.3 1.8e-33 NP_001171662 (OMIM: 607581) solute carrier family ( 451) 576 133.3 9.3e-31 NP_006663 (OMIM: 604995) solute carrier family 22 ( 546) 512 119.6 1.4e-26 XP_006715034 (OMIM: 604995) PREDICTED: solute carr ( 549) 507 118.6 3e-26 NP_696961 (OMIM: 604995) solute carrier family 22 ( 548) 498 116.6 1.2e-25 XP_006715033 (OMIM: 604995) PREDICTED: solute carr ( 551) 493 115.6 2.5e-25 NP_001004326 (OMIM: 611696) solute carrier family ( 349) 474 111.3 3.1e-24 XP_011543345 (OMIM: 611696) PREDICTED: solute carr ( 417) 474 111.4 3.5e-24 XP_016873263 (OMIM: 611696) PREDICTED: solute carr ( 483) 474 111.4 3.8e-24 NP_004247 (OMIM: 604047) solute carrier family 22 ( 551) 462 108.9 2.5e-23 XP_011543666 (OMIM: 607581) PREDICTED: solute carr ( 419) 429 101.7 2.8e-21 NP_001171665 (OMIM: 607581) solute carrier family ( 419) 429 101.7 2.8e-21 XP_011534512 (OMIM: 608276) PREDICTED: solute carr ( 423) 429 101.7 2.8e-21 XP_011534507 (OMIM: 608276) PREDICTED: solute carr ( 515) 429 101.8 3.2e-21 NP_149116 (OMIM: 608276) solute carrier family 22 ( 577) 429 101.9 3.5e-21 XP_006715615 (OMIM: 602607) PREDICTED: solute carr ( 483) 416 99.0 2.1e-20 NP_694857 (OMIM: 602607) solute carrier family 22 ( 506) 416 99.0 2.2e-20 NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 416 99.0 2.3e-20 XP_005267160 (OMIM: 602607) PREDICTED: solute carr ( 573) 416 99.1 2.4e-20 >>NP_775857 (OMIM: 611698) solute carrier family 22 memb (322 aa) initn: 2180 init1: 2180 opt: 2180 Z-score: 2535.7 bits: 477.4 E(85289): 1.7e-134 Smith-Waterman score: 2180; 99.4% identity (100.0% similar) in 322 aa overlap (1-322:1-322) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: NP_775 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWYEQSPHSLPVSEAMVDIERKIVT ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_775 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWYEQSPHSLPVSEAMVDIERKILT 250 260 270 280 290 300 310 320 pF1KB5 PGICSVSGLVLSHDVHSTYCVT :::::::::::::::::::::: NP_775 PGICSVSGLVLSHDVHSTYCVT 310 320 >>NP_001129978 (OMIM: 611698) solute carrier family 22 m (552 aa) initn: 1909 init1: 1885 opt: 1885 Z-score: 2190.8 bits: 414.4 E(85289): 2.8e-115 Smith-Waterman score: 1885; 99.6% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: NP_001 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWYEQSPHSLPVSEAMVDIERKIVT ::::::::::::::::::::::::::::::::::::: NP_001 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELR 250 260 270 280 290 300 310 320 pF1KB5 PGICSVSGLVLSHDVHSTYCVT NP_001 RVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAI 310 320 330 340 350 360 >>XP_016872648 (OMIM: 607579) PREDICTED: solute carrier (445 aa) initn: 1221 init1: 1200 opt: 1222 Z-score: 1422.7 bits: 272.0 E(85289): 1.7e-72 Smith-Waterman score: 1222; 59.5% identity (83.0% similar) in 289 aa overlap (1-288:1-289) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. :: ..: . :::: .:. : . . ...::::::: :.::::: .::::.:: XP_016 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :::::.::.: :::::::::::.::.::.::.::::::::::::::::.. : ::::::: XP_016 DNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::: :: :::::::::::.:::: :... .:::: ..::.. :::::: ::... . :. XP_016 VYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS ::.:: .::::.:::::.:: ::::.:...:... ::..: ::. : ..: : . .: XP_016 LQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCP 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAMVDIERKIV ... : :.::::::.:::::::.::.: .:.:: ::: .: . : .. XP_016 SGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELR 250 260 270 280 290 300 300 310 320 pF1KB5 TPGICSVSGLVLSHDVHSTYCVT XP_016 KAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFA 310 320 330 340 350 360 >>NP_543142 (OMIM: 607579) solute carrier family 22 memb (553 aa) initn: 1200 init1: 1200 opt: 1222 Z-score: 1421.6 bits: 272.1 E(85289): 1.9e-72 Smith-Waterman score: 1222; 59.5% identity (83.0% similar) in 289 aa overlap (1-288:1-289) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. :: ..: . :::: .:. : . . ...::::::: :.::::: .::::.:: NP_543 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :::::.::.: :::::::::::.::.::.::.::::::::::::::::.. : ::::::: NP_543 DNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::: :: :::::::::::.:::: :... .:::: ..::.. :::::: ::... . :. NP_543 VYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS ::.:: .::::.:::::.:: ::::.:...:... ::..: ::. : ..: : . .: NP_543 LQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCP 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAMVDIERKIV ... : :.::::::.:::::::.::.: .:.:: ::: .: . : .. NP_543 SGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELR 250 260 270 280 290 300 300 310 320 pF1KB5 TPGICSVSGLVLSHDVHSTYCVT NP_543 KAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFA 310 320 330 340 350 360 >>NP_955384 (OMIM: 610792) solute carrier family 22 memb (547 aa) initn: 1238 init1: 1194 opt: 1217 Z-score: 1415.8 bits: 271.0 E(85289): 4e-72 Smith-Waterman score: 1217; 60.2% identity (83.4% similar) in 289 aa overlap (1-288:1-289) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. :::::::.::::: ..:. . :.... . ::::.:: .::::: .::::.. NP_955 MAFQDLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTIP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW ::: ::::.: :::::::.::::::.::.::.::::.:.:::::::::.::::::::::: NP_955 DNDPGTLSQDALLRISIPFDSNLRPEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::.::: :::::.:::::::: :.:... ::::: ..:: .::::::: :::.. . . NP_955 VYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLRWSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS ::::: .::::::::.:::: :::::: .:..:. :: .: .:: . .:.. . ::. NP_955 LQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTLCA 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAMVDIERKIV :.:.. ::.:::.:.: ::::..:.: .:.:: : : .: . : .. NP_955 ASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELR 250 260 270 280 290 300 300 310 320 pF1KB5 TPGICSVSGLVLSHDVHSTYCVT NP_955 KAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSFVRFAS 310 320 330 340 350 360 >>XP_016873176 (OMIM: 610792) PREDICTED: solute carrier (547 aa) initn: 1238 init1: 1194 opt: 1217 Z-score: 1415.8 bits: 271.0 E(85289): 4e-72 Smith-Waterman score: 1217; 60.2% identity (83.4% similar) in 289 aa overlap (1-288:1-289) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. :::::::.::::: ..:. . :.... . ::::.:: .::::: .::::.. XP_016 MAFQDLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTIP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW ::: ::::.: :::::::.::::::.::.::.::::.:.:::::::::.::::::::::: XP_016 DNDPGTLSQDALLRISIPFDSNLRPEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::.::: :::::.:::::::: :.:... ::::: ..:: .::::::: :::.. . . XP_016 VYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLRWSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS ::::: .::::::::.:::: :::::: .:..:. :: .: .:: . .:.. . ::. XP_016 LQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTLCA 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAMVDIERKIV :.:.. ::.:::.:.: ::::..:.: .:.:: : : .: . : .. XP_016 ASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELR 250 260 270 280 290 300 300 310 320 pF1KB5 TPGICSVSGLVLSHDVHSTYCVT XP_016 KAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSFVRFAS 310 320 330 340 350 360 >>XP_016873191 (OMIM: 607580) PREDICTED: solute carrier (365 aa) initn: 1198 init1: 1167 opt: 1195 Z-score: 1392.4 bits: 266.1 E(85289): 8.1e-71 Smith-Waterman score: 1195; 56.2% identity (82.5% similar) in 308 aa overlap (1-303:1-308) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. ::.::::.::::. ..:. . .::.:.:.::::.: :.::::: .:::.. : XP_016 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :.:: ::.: ::::::::::::::.::.::.::::::::::::. .:.: ::::::::: XP_016 GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::.: : :::::.:::::. :::::.:: :...: :.::.: ::.::: ::..: . :. XP_016 VYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS :::::..::::::::: :::.::::::::.: :..:. . :: : :....... . XP_016 LQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGA 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAM---VDIER :.::..:::::....::. :....:.:..:.:: : : .: . : ... . . : XP_016 LSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALR 250 260 270 280 290 300 300 310 320 pF1KB5 KIV-TPGICSVSGLVLSHDVHSTYCVT :.. : :: XP_016 KVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRKKN 310 320 330 340 350 360 >>XP_016873190 (OMIM: 607580) PREDICTED: solute carrier (424 aa) initn: 1198 init1: 1167 opt: 1195 Z-score: 1391.6 bits: 266.1 E(85289): 9e-71 Smith-Waterman score: 1195; 56.2% identity (82.5% similar) in 308 aa overlap (1-303:1-308) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. ::.::::.::::. ..:. . .::.:.:.::::.: :.::::: .:::.. : XP_016 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :.:: ::.: ::::::::::::::.::.::.::::::::::::. .:.: ::::::::: XP_016 GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::.: : :::::.:::::. :::::.:: :...: :.::.: ::.::: ::..: . :. XP_016 VYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS :::::..::::::::: :::.::::::::.: :..:. . :: : :....... . XP_016 LQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGA 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAM---VDIER :.::..:::::....::. :....:.:..:.:: : : .: . : ... . . : XP_016 LSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALR 250 260 270 280 290 300 300 310 320 pF1KB5 KIV-TPGICSVSGLVLSHDVHSTYCVT :.. : :: XP_016 KVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFAN 310 320 330 340 350 360 >>XP_011543318 (OMIM: 607580) PREDICTED: solute carrier (541 aa) initn: 1198 init1: 1167 opt: 1195 Z-score: 1390.4 bits: 266.3 E(85289): 1e-70 Smith-Waterman score: 1195; 56.2% identity (82.5% similar) in 308 aa overlap (1-303:1-308) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. ::.::::.::::. ..:. . .::.:.:.::::.: :.::::: .:::.. : XP_011 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :.:: ::.: ::::::::::::::.::.::.::::::::::::. .:.: ::::::::: XP_011 GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::.: : :::::.:::::. :::::.:: :...: :.::.: ::.::: ::..: . :. XP_011 VYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS :::::..::::::::: :::.::::::::.: :..:. . :: : :....... . XP_011 LQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGA 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAM---VDIER :.::..:::::....::. :....:.:..:.:: : : .: . : ... . . : XP_011 LSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALR 250 260 270 280 290 300 300 310 320 pF1KB5 KIV-TPGICSVSGLVLSHDVHSTYCVT :.. : :: XP_011 KVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFAN 310 320 330 340 350 360 >>NP_001034841 (OMIM: 607580) solute carrier family 22 m (541 aa) initn: 1198 init1: 1167 opt: 1195 Z-score: 1390.4 bits: 266.3 E(85289): 1e-70 Smith-Waterman score: 1195; 56.2% identity (82.5% similar) in 308 aa overlap (1-303:1-308) 10 20 30 40 50 60 pF1KB5 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDSVS :.:. ::.::::.::::. ..:. . .::.:.:.::::.: :.::::: .:::.. : NP_001 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGW :.:: ::.: ::::::::::::::.::.::.::::::::::::. .:.: ::::::::: NP_001 GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCF :::.: : :::::.:::::. :::::.:: :...: :.::.: ::.::: ::..: . :. NP_001 VYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCS :::::..::::::::: :::.::::::::.: :..:. . :: : :....... . NP_001 LQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGA 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 YSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFL-SSWYEQSPHSLPVSEAM---VDIER :.::..:::::....::. :....:.:..:.:: : : .: . : ... . . : NP_001 LSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALR 250 260 270 280 290 300 300 310 320 pF1KB5 KIV-TPGICSVSGLVLSHDVHSTYCVT :.. : :: NP_001 KVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFAN 310 320 330 340 350 360 322 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:30:49 2016 done: Sat Nov 5 10:30:50 2016 Total Scan time: 6.360 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]