FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5861, 461 aa
  1>>>pF1KB5861 461 - 461 aa - 461 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2136+/-0.00105; mu= 1.1247+/- 0.063
 mean_var=254.4063+/-50.839, 0's: 0 Z-trim(112.8): 32  B-trim: 309 in 1/51
 Lambda= 0.080410
 statistics sampled from 13520 (13535) to 13520 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.416), width:  16
 Scan time:  3.630

The best scores are:                                      opt bits E(32554)
CCDS12740.1 NUCB1 gene_id:4924|Hs108|chr19         ( 461) 3036 365.3 7.4e-101
CCDS41623.1 NUCB2 gene_id:4925|Hs108|chr11         ( 420) 1637 203.0   5e-52
CCDS81556.1 NUCB2 gene_id:4925|Hs108|chr11         ( 390) 1333 167.7 1.9e-41


>>CCDS12740.1 NUCB1 gene_id:4924|Hs108|chr19              (461 aa)
 initn: 3036 init1: 3036 opt: 3036  Z-score: 1924.1  bits: 365.3 E(32554): 7.4e-101
Smith-Waterman score: 3036; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)

               10        20        30        40        50        60
pF1KB5 MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 VLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 VLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 AEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 MLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 NRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELAAREAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELAAREAE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 LNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAHPEGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAHPEGQL
              370       380       390       400       410       420

              430       440       450       460 
pF1KB5 KFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
       :::::::::::::::::::::::::::::::::::::::::
CCDS12 KFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
              430       440       450       460 

>>CCDS41623.1 NUCB2 gene_id:4925|Hs108|chr11              (420 aa)
 initn: 1210 init1: 985 opt: 1637  Z-score: 1047.6  bits: 203.0 E(32554): 5e-52
Smith-Waterman score: 1637; 61.4% identity (81.9% similar) in 415 aa overlap (15-424:13-418)

               10        20        30             40        50     
pF1KB5 MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKE-----ETPATESPDTGLYYHRYL
                     ::.  :: :. :::..    . .     :.   : ::::::: .::
CCDS41   MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYL
                 10        20        30        40        50        

          60        70        80        90       100       110     
pF1KB5 QEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLL
       ..:::::::: ::::::: :. :.::::.::.:::.:::::::::::::::::.:::::.
CCDS41 KQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLI
       60        70        80        90       100       110        

         120       130       140       150       160       170     
pF1KB5 KAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEE
       :::.:. ::  . .::  :::::.::.  :   ::. ::..::..:: :: .:: ..:::
CCDS41 KAKLDSLQD--IGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEE
      120         130       140       150       160       170      

         180       190       200       210       220       230     
pF1KB5 FKRYEMLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEEL
       ::.:::.::::::.::..:.::.::: : :.::....:..::::: :::. :::::::: 
CCDS41 FKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEET
        180       190       200       210       220       230      

         240       250       260       270       280       290     
pF1KB5 DGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLR
       :::::: :.::::: :::.:::: ::::::::::::::::::::::::::: ::::::::
CCDS41 DGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLR
        240       250       260       270       280       290      

         300       310       320       330       340       350     
pF1KB5 MREHVMKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELA
       ::::::..::::.:::::::::: .:..::: .  ..:::....  .:::::...:. .:
CCDS41 MREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEP-DSWETLDQQQFFTEEELKEYENIIA
        300       310       320       330        340       350     

         360       370       380       390       400       410     
pF1KB5 AREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAH
        .: ::. ::..:... : : :.. .::::: : .:.. .:::.: ::        : . 
CCDS41 LQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQG------IPPSG
         360       370       380       390       400               

         420       430       440       450       460 
pF1KB5 PEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
       : :.:::.:                                     
CCDS41 PAGELKFEPHI                                   
     410       420                                   

>>CCDS81556.1 NUCB2 gene_id:4925|Hs108|chr11              (390 aa)
 initn: 1076 init1: 868 opt: 1333  Z-score: 857.4  bits: 167.7 E(32554): 1.9e-41
Smith-Waterman score: 1446; 56.9% identity (75.4% similar) in 415 aa overlap (15-424:13-388)

               10        20        30             40        50     
pF1KB5 MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKE-----ETPATESPDTGLYYHRYL
                     ::.  :: :. :::..    . .     :.   : ::::::: .::
CCDS81   MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYL
                 10        20        30        40        50        

          60        70        80        90       100       110     
pF1KB5 QEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLL
       ..:::::::: ::::::: :. :.::::.::.:::.:::::::::::::::::.:::::.
CCDS81 KQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLI
       60        70        80        90       100       110        

         120       130       140       150       160       170     
pF1KB5 KAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEE
       :::.:. ::  . .::  :::::.::.  :   ::. ::..::..:: :: .:: ..:::
CCDS81 KAKLDSLQD--IGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEE
      120         130       140       150       160       170      

         180       190       200       210       220       230     
pF1KB5 FKRYEMLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEEL
       ::.:::.::::::.::..:.::.::: : :.::....:..::::: :::. :::::::: 
CCDS81 FKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEET
        180       190       200       210       220       230      

         240       250       260       270       280       290     
pF1KB5 DGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLR
       :::::: :.::::: :::.:::: ::::::::::::::::::::::::::: ::::::::
CCDS81 DGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLR
        240       250       260       270       280       290      

         300       310       320       330       340       350     
pF1KB5 MREHVMKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELA
       ::::::.                               ::....  .:::::...:. .:
CCDS81 MREHVMN-------------------------------ETLDQQQFFTEEELKEYENIIA
        300                                      310       320     

         360       370       380       390       400       410     
pF1KB5 AREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAH
        .: ::. ::..:... : : :.. .::::: : .:.. .:::.: ::        : . 
CCDS81 LQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQG------IPPSG
         330       340       350       360       370               

         420       430       440       450       460 
pF1KB5 PEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
       : :.:::.:                                     
CCDS81 PAGELKFEPHI                                   
     380       390                                   




461 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:22:15 2016 done: Sat Nov  5 15:22:15 2016
 Total Scan time:  3.630 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]