FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5866, 491 aa
1>>>pF1KB5866 491 - 491 aa - 491 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7783+/-0.000321; mu= 17.7889+/- 0.020
mean_var=97.8636+/-19.338, 0's: 0 Z-trim(117.9): 85 B-trim: 23 in 1/53
Lambda= 0.129647
statistics sampled from 30220 (30305) to 30220 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.355), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_005132 (OMIM: 134830,202400,616004) fibrinogen ( 491) 3434 652.5 7.9e-187
NP_001171670 (OMIM: 134830,202400,616004) fibrinog ( 432) 2653 506.4 6.8e-143
NP_000500 (OMIM: 134850,202400,616004) fibrinogen ( 437) 560 114.9 4.8e-25
NP_068656 (OMIM: 134850,202400,616004) fibrinogen ( 453) 560 114.9 4.9e-25
XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen- ( 282) 338 73.2 1.1e-12
XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen- ( 312) 338 73.2 1.2e-12
NP_963847 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12
NP_963846 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12
NP_671736 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12
NP_004458 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12
NP_036230 (OMIM: 605001) angiopoietin-related prot ( 493) 302 66.7 1.8e-10
NP_006673 (OMIM: 605351) fibroleukin precursor [Ho ( 439) 287 63.8 1.1e-09
NP_001138578 (OMIM: 613357) fibrinogen C domain-co ( 461) 272 61.0 8.2e-09
NP_116232 (OMIM: 613357) fibrinogen C domain-conta ( 461) 272 61.0 8.2e-09
NP_000499 (OMIM: 105200,134820,202400,616004) fibr ( 866) 275 61.8 8.9e-09
XP_016868807 (OMIM: 601922) PREDICTED: angiopoieti ( 443) 271 60.8 9e-09
NP_001112360 (OMIM: 601922) angiopoietin-2 isoform ( 444) 271 60.8 9.1e-09
NP_001112359 (OMIM: 601922) angiopoietin-2 isoform ( 495) 271 60.9 9.8e-09
NP_001138 (OMIM: 601922) angiopoietin-2 isoform a ( 496) 271 60.9 9.8e-09
NP_001309738 (OMIM: 603705) angiopoietin-4 isoform ( 410) 257 58.2 5.2e-08
XP_011527541 (OMIM: 603705) PREDICTED: angiopoieti ( 451) 257 58.2 5.6e-08
NP_057069 (OMIM: 603705) angiopoietin-4 isoform 1 ( 503) 257 58.3 6.1e-08
NP_647475 (OMIM: 605910,615881) angiopoietin-relat ( 406) 254 57.6 7.7e-08
XP_005272541 (OMIM: 605910,615881) PREDICTED: angi ( 424) 249 56.7 1.5e-07
XP_011526649 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 248 56.6 1.9e-07
NP_001308340 (OMIM: 609336) angiopoietin-related p ( 470) 248 56.6 1.9e-07
XP_016882836 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 248 56.6 1.9e-07
XP_011526652 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 248 56.6 1.9e-07
NP_114123 (OMIM: 609336) angiopoietin-related prot ( 470) 248 56.6 1.9e-07
XP_011526651 (OMIM: 609336) PREDICTED: angiopoieti ( 537) 248 56.6 2.1e-07
XP_011526650 (OMIM: 609336) PREDICTED: angiopoieti ( 537) 248 56.6 2.1e-07
XP_005260148 (OMIM: 609336) PREDICTED: angiopoieti ( 551) 248 56.6 2.1e-07
XP_016872955 (OMIM: 607666) PREDICTED: angiopoieti ( 248) 242 55.2 2.5e-07
NP_001300980 (OMIM: 601667) angiopoietin-1 isoform ( 298) 242 55.3 2.9e-07
NP_775628 (OMIM: 604973,613860) ficolin-3 isoform ( 288) 240 54.9 3.6e-07
NP_003656 (OMIM: 604973,613860) ficolin-3 isoform ( 299) 240 54.9 3.7e-07
NP_001186788 (OMIM: 601667) angiopoietin-1 isoform ( 497) 242 55.4 4.2e-07
NP_001137 (OMIM: 601667) angiopoietin-1 isoform 1 ( 498) 242 55.4 4.2e-07
NP_002395 (OMIM: 600596) microfibril-associated gl ( 255) 238 54.5 4.3e-07
NP_001185624 (OMIM: 600596) microfibril-associated ( 279) 238 54.5 4.6e-07
XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 i ( 264) 236 54.1 5.7e-07
NP_056652 (OMIM: 601624) ficolin-2 isoform b precu ( 275) 236 54.1 5.9e-07
XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 i ( 302) 236 54.1 6.3e-07
NP_004099 (OMIM: 601624) ficolin-2 isoform a precu ( 313) 236 54.2 6.5e-07
NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo ( 326) 231 53.2 1.3e-06
XP_005245634 (OMIM: 603874) PREDICTED: angiopoieti ( 491) 233 53.8 1.3e-06
NP_004664 (OMIM: 603874) angiopoietin-related prot ( 491) 233 53.8 1.3e-06
NP_835228 (OMIM: 607666) angiopoietin-related prot ( 388) 216 50.5 1e-05
NP_001315564 (OMIM: 601995) tenascin-R isoform 2 [ (1025) 219 51.4 1.4e-05
XP_011508251 (OMIM: 601995) PREDICTED: tenascin-R (1199) 219 51.5 1.6e-05
>>NP_005132 (OMIM: 134830,202400,616004) fibrinogen beta (491 aa)
initn: 3434 init1: 3434 opt: 3434 Z-score: 3475.2 bits: 652.5 E(85289): 7.9e-187
Smith-Waterman score: 3434; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491)
10 20 30 40 50 60
pF1KB5 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
430 440 450 460 470 480
490
pF1KB5 SMKIRPFFPQQ
:::::::::::
NP_005 SMKIRPFFPQQ
490
>>NP_001171670 (OMIM: 134830,202400,616004) fibrinogen b (432 aa)
initn: 2649 init1: 2649 opt: 2653 Z-score: 2686.4 bits: 506.4 E(85289): 6.8e-143
Smith-Waterman score: 2884; 88.0% identity (88.0% similar) in 491 aa overlap (1-491:1-432)
10 20 30 40 50 60
pF1KB5 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEA----
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE
:::::
NP_001 -------------------------------------------------------LLQQE
60
130 140 150 160 170 180
pF1KB5 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB5 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB5 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB5 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
370 380 390 400 410 420
490
pF1KB5 SMKIRPFFPQQ
:::::::::::
NP_001 SMKIRPFFPQQ
430
>>NP_000500 (OMIM: 134850,202400,616004) fibrinogen gamm (437 aa)
initn: 806 init1: 295 opt: 560 Z-score: 570.7 bits: 114.9 E(85289): 4.8e-25
Smith-Waterman score: 827; 33.2% identity (64.2% similar) in 400 aa overlap (95-487:34-415)
70 80 90 100 110 120
pF1KB5 PISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIR
: : .: ::: : . . : . .
NP_000 SLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQTKVD
10 20 30 40 50 60
130 140 150 160 170 180
pF1KB5 NSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYID
.... :.. .. : . .: : . .. .. ... . .... : .. .. . .
NP_000 KDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYE
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB5 ETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQME-YCRTPCTVSCNIPVVSGKECEE
.. .. ...: :. : .. .:: .:. : ::.: :. :: . .: ..::.:..
NP_000 ASILTH-DSSIRYLQEIYNSNNQKIVNLKEKV-AQLEAQCQEPCKDTVQIHDITGKDCQD
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 IIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGF
: ::.. : .:.:.: .. . . :::... ..::::.:.: :::::: ..: ::.::
NP_000 IANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGF
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 GNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG--PTELLIEMEDWKGDKVKAHYGGFTV
:... . : . :.::::.:: .. .. : : .:.:::.: : :. : :
NP_000 GHLSPT--GTT------EFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKV
250 260 270 280 290
370 380 390 400 410
pF1KB5 QNEANKYQISVNKYRG-TAGNALMDGASQLMGEN---RTMTIHNGMFFSTYDRDNDGWLT
::.::... . : ::.:. :: . .:.. . .: :::: :::.: ::: .
NP_000 GPEADKYRLTYAYFAGGDAGDAF-DGFD--FGDDPSDKFFTSHNGMQFSTWDNDNDKF--
300 310 320 330 340
420 430 440 450 460 470
pF1KB5 SDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSM
. .:...::.:::.:.:::.. :: :: :: :. . .: :.:..: .:: ::::
NP_000 ---EGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSM
350 360 370 380 390 400
480 490
pF1KB5 RKMSMKIRPFFPQQ
.: .::: ::
NP_000 KKTTMKIIPFNRLTIGEGQQHHLGGAKQAGDV
410 420 430
>>NP_068656 (OMIM: 134850,202400,616004) fibrinogen gamm (453 aa)
initn: 779 init1: 295 opt: 560 Z-score: 570.4 bits: 114.9 E(85289): 4.9e-25
Smith-Waterman score: 827; 33.2% identity (64.2% similar) in 400 aa overlap (95-487:34-415)
70 80 90 100 110 120
pF1KB5 PISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIR
: : .: ::: : . . : . .
NP_068 SLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQTKVD
10 20 30 40 50 60
130 140 150 160 170 180
pF1KB5 NSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYID
.... :.. .. : . .: : . .. .. ... . .... : .. .. . .
NP_068 KDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYE
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB5 ETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQME-YCRTPCTVSCNIPVVSGKECEE
.. .. ...: :. : .. .:: .:. : ::.: :. :: . .: ..::.:..
NP_068 ASILTH-DSSIRYLQEIYNSNNQKIVNLKEKV-AQLEAQCQEPCKDTVQIHDITGKDCQD
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 IIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGF
: ::.. : .:.:.: .. . . :::... ..::::.:.: :::::: ..: ::.::
NP_068 IANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGF
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 GNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG--PTELLIEMEDWKGDKVKAHYGGFTV
:... . : . :.::::.:: .. .. : : .:.:::.: : :. : :
NP_068 GHLSPT--GTT------EFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKV
250 260 270 280 290
370 380 390 400 410
pF1KB5 QNEANKYQISVNKYRG-TAGNALMDGASQLMGEN---RTMTIHNGMFFSTYDRDNDGWLT
::.::... . : ::.:. :: . .:.. . .: :::: :::.: ::: .
NP_068 GPEADKYRLTYAYFAGGDAGDAF-DGFD--FGDDPSDKFFTSHNGMQFSTWDNDNDKF--
300 310 320 330 340
420 430 440 450 460 470
pF1KB5 SDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSM
. .:...::.:::.:.:::.. :: :: :: :. . .: :.:..: .:: ::::
NP_068 ---EGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSM
350 360 370 380 390 400
480 490
pF1KB5 RKMSMKIRPFFPQQ
.: .::: ::
NP_068 KKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL
410 420 430 440 450
>>XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen-like (282 aa)
initn: 575 init1: 162 opt: 338 Z-score: 348.8 bits: 73.2 E(85289): 1.1e-12
Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:7-279)
170 180 190 200 210 220
pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR
.:.:.. ... . ::..: .. .:.
XP_016 MRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG
10 20 30
230 240 250 260 270 280
pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV
:: : . : .. : ::. : . : .: :.: .: . ::::: ...:::::
XP_016 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL
:: :.::: .:.: : :..::: :. ::::::: .. :: . :
XP_016 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK
100 110 120 130 140
350 360 370 380 390 400
pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN
:.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :.
XP_016 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ
150 160 170 180 190 200
410 420 430 440 450 460
pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT
: :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: :
XP_016 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T
210 220 230 240
470 480 490
pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ
:.:.::..:.: :::.... ::::: :.:
XP_016 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
250 260 270 280
>>XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen-like (312 aa)
initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12
Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309)
170 180 190 200 210 220
pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR
.:.:.. ... . ::..: .. .:.
XP_016 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG
10 20 30 40 50 60
230 240 250 260 270 280
pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV
:: : . : .. : ::. : . : .: :.: .: . ::::: ...:::::
XP_016 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV
70 80 90 100 110 120
290 300 310 320 330 340
pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL
:: :.::: .:.: : :..::: :. ::::::: .. :: . :
XP_016 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK
130 140 150 160 170
350 360 370 380 390 400
pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN
:.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :.
XP_016 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ
180 190 200 210 220 230
410 420 430 440 450 460
pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT
: :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: :
XP_016 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T
240 250 260 270
470 480 490
pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ
:.:.::..:.: :::.... ::::: :.:
XP_016 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
280 290 300 310
>>NP_963847 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12
Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309)
170 180 190 200 210 220
pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR
.:.:.. ... . ::..: .. .:.
NP_963 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG
10 20 30 40 50 60
230 240 250 260 270 280
pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV
:: : . : .. : ::. : . : .: :.: .: . ::::: ...:::::
NP_963 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV
70 80 90 100 110 120
290 300 310 320 330 340
pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL
:: :.::: .:.: : :..::: :. ::::::: .. :: . :
NP_963 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK
130 140 150 160 170
350 360 370 380 390 400
pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN
:.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :.
NP_963 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ
180 190 200 210 220 230
410 420 430 440 450 460
pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT
: :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: :
NP_963 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T
240 250 260 270
470 480 490
pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ
:.:.::..:.: :::.... ::::: :.:
NP_963 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
280 290 300 310
>>NP_963846 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12
Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309)
170 180 190 200 210 220
pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR
.:.:.. ... . ::..: .. .:.
NP_963 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG
10 20 30 40 50 60
230 240 250 260 270 280
pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV
:: : . : .. : ::. : . : .: :.: .: . ::::: ...:::::
NP_963 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV
70 80 90 100 110 120
290 300 310 320 330 340
pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL
:: :.::: .:.: : :..::: :. ::::::: .. :: . :
NP_963 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK
130 140 150 160 170
350 360 370 380 390 400
pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN
:.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :.
NP_963 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ
180 190 200 210 220 230
410 420 430 440 450 460
pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT
: :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: :
NP_963 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T
240 250 260 270
470 480 490
pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ
:.:.::..:.: :::.... ::::: :.:
NP_963 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
280 290 300 310
>>NP_671736 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12
Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309)
170 180 190 200 210 220
pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR
.:.:.. ... . ::..: .. .:.
NP_671 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG
10 20 30 40 50 60
230 240 250 260 270 280
pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV
:: : . : .. : ::. : . : .: :.: .: . ::::: ...:::::
NP_671 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV
70 80 90 100 110 120
290 300 310 320 330 340
pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL
:: :.::: .:.: : :..::: :. ::::::: .. :: . :
NP_671 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK
130 140 150 160 170
350 360 370 380 390 400
pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN
:.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :.
NP_671 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ
180 190 200 210 220 230
410 420 430 440 450 460
pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT
: :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: :
NP_671 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T
240 250 260 270
470 480 490
pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ
:.:.::..:.: :::.... ::::: :.:
NP_671 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
280 290 300 310
>>NP_004458 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa)
initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12
Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309)
170 180 190 200 210 220
pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR
.:.:.. ... . ::..: .. .:.
NP_004 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG
10 20 30 40 50 60
230 240 250 260 270 280
pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV
:: : . : .. : ::. : . : .: :.: .: . ::::: ...:::::
NP_004 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV
70 80 90 100 110 120
290 300 310 320 330 340
pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL
:: :.::: .:.: : :..::: :. ::::::: .. :: . :
NP_004 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK
130 140 150 160 170
350 360 370 380 390 400
pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN
:.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :.
NP_004 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ
180 190 200 210 220 230
410 420 430 440 450 460
pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT
: :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: :
NP_004 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T
240 250 260 270
470 480 490
pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ
:.:.::..:.: :::.... ::::: :.:
NP_004 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
280 290 300 310
491 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:33:04 2016 done: Sat Nov 5 16:33:06 2016
Total Scan time: 9.950 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]