FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5866, 491 aa 1>>>pF1KB5866 491 - 491 aa - 491 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7783+/-0.000321; mu= 17.7889+/- 0.020 mean_var=97.8636+/-19.338, 0's: 0 Z-trim(117.9): 85 B-trim: 23 in 1/53 Lambda= 0.129647 statistics sampled from 30220 (30305) to 30220 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.355), width: 16 Scan time: 9.950 The best scores are: opt bits E(85289) NP_005132 (OMIM: 134830,202400,616004) fibrinogen ( 491) 3434 652.5 7.9e-187 NP_001171670 (OMIM: 134830,202400,616004) fibrinog ( 432) 2653 506.4 6.8e-143 NP_000500 (OMIM: 134850,202400,616004) fibrinogen ( 437) 560 114.9 4.8e-25 NP_068656 (OMIM: 134850,202400,616004) fibrinogen ( 453) 560 114.9 4.9e-25 XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen- ( 282) 338 73.2 1.1e-12 XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen- ( 312) 338 73.2 1.2e-12 NP_963847 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12 NP_963846 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12 NP_671736 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12 NP_004458 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 338 73.2 1.2e-12 NP_036230 (OMIM: 605001) angiopoietin-related prot ( 493) 302 66.7 1.8e-10 NP_006673 (OMIM: 605351) fibroleukin precursor [Ho ( 439) 287 63.8 1.1e-09 NP_001138578 (OMIM: 613357) fibrinogen C domain-co ( 461) 272 61.0 8.2e-09 NP_116232 (OMIM: 613357) fibrinogen C domain-conta ( 461) 272 61.0 8.2e-09 NP_000499 (OMIM: 105200,134820,202400,616004) fibr ( 866) 275 61.8 8.9e-09 XP_016868807 (OMIM: 601922) PREDICTED: angiopoieti ( 443) 271 60.8 9e-09 NP_001112360 (OMIM: 601922) angiopoietin-2 isoform ( 444) 271 60.8 9.1e-09 NP_001112359 (OMIM: 601922) angiopoietin-2 isoform ( 495) 271 60.9 9.8e-09 NP_001138 (OMIM: 601922) angiopoietin-2 isoform a ( 496) 271 60.9 9.8e-09 NP_001309738 (OMIM: 603705) angiopoietin-4 isoform ( 410) 257 58.2 5.2e-08 XP_011527541 (OMIM: 603705) PREDICTED: angiopoieti ( 451) 257 58.2 5.6e-08 NP_057069 (OMIM: 603705) angiopoietin-4 isoform 1 ( 503) 257 58.3 6.1e-08 NP_647475 (OMIM: 605910,615881) angiopoietin-relat ( 406) 254 57.6 7.7e-08 XP_005272541 (OMIM: 605910,615881) PREDICTED: angi ( 424) 249 56.7 1.5e-07 XP_011526649 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 248 56.6 1.9e-07 NP_001308340 (OMIM: 609336) angiopoietin-related p ( 470) 248 56.6 1.9e-07 XP_016882836 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 248 56.6 1.9e-07 XP_011526652 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 248 56.6 1.9e-07 NP_114123 (OMIM: 609336) angiopoietin-related prot ( 470) 248 56.6 1.9e-07 XP_011526651 (OMIM: 609336) PREDICTED: angiopoieti ( 537) 248 56.6 2.1e-07 XP_011526650 (OMIM: 609336) PREDICTED: angiopoieti ( 537) 248 56.6 2.1e-07 XP_005260148 (OMIM: 609336) PREDICTED: angiopoieti ( 551) 248 56.6 2.1e-07 XP_016872955 (OMIM: 607666) PREDICTED: angiopoieti ( 248) 242 55.2 2.5e-07 NP_001300980 (OMIM: 601667) angiopoietin-1 isoform ( 298) 242 55.3 2.9e-07 NP_775628 (OMIM: 604973,613860) ficolin-3 isoform ( 288) 240 54.9 3.6e-07 NP_003656 (OMIM: 604973,613860) ficolin-3 isoform ( 299) 240 54.9 3.7e-07 NP_001186788 (OMIM: 601667) angiopoietin-1 isoform ( 497) 242 55.4 4.2e-07 NP_001137 (OMIM: 601667) angiopoietin-1 isoform 1 ( 498) 242 55.4 4.2e-07 NP_002395 (OMIM: 600596) microfibril-associated gl ( 255) 238 54.5 4.3e-07 NP_001185624 (OMIM: 600596) microfibril-associated ( 279) 238 54.5 4.6e-07 XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 i ( 264) 236 54.1 5.7e-07 NP_056652 (OMIM: 601624) ficolin-2 isoform b precu ( 275) 236 54.1 5.9e-07 XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 i ( 302) 236 54.1 6.3e-07 NP_004099 (OMIM: 601624) ficolin-2 isoform a precu ( 313) 236 54.2 6.5e-07 NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo ( 326) 231 53.2 1.3e-06 XP_005245634 (OMIM: 603874) PREDICTED: angiopoieti ( 491) 233 53.8 1.3e-06 NP_004664 (OMIM: 603874) angiopoietin-related prot ( 491) 233 53.8 1.3e-06 NP_835228 (OMIM: 607666) angiopoietin-related prot ( 388) 216 50.5 1e-05 NP_001315564 (OMIM: 601995) tenascin-R isoform 2 [ (1025) 219 51.4 1.4e-05 XP_011508251 (OMIM: 601995) PREDICTED: tenascin-R (1199) 219 51.5 1.6e-05 >>NP_005132 (OMIM: 134830,202400,616004) fibrinogen beta (491 aa) initn: 3434 init1: 3434 opt: 3434 Z-score: 3475.2 bits: 652.5 E(85289): 7.9e-187 Smith-Waterman score: 3434; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491) 10 20 30 40 50 60 pF1KB5 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM 430 440 450 460 470 480 490 pF1KB5 SMKIRPFFPQQ ::::::::::: NP_005 SMKIRPFFPQQ 490 >>NP_001171670 (OMIM: 134830,202400,616004) fibrinogen b (432 aa) initn: 2649 init1: 2649 opt: 2653 Z-score: 2686.4 bits: 506.4 E(85289): 6.8e-143 Smith-Waterman score: 2884; 88.0% identity (88.0% similar) in 491 aa overlap (1-491:1-432) 10 20 30 40 50 60 pF1KB5 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEA---- 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE ::::: NP_001 -------------------------------------------------------LLQQE 60 130 140 150 160 170 180 pF1KB5 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB5 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB5 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB5 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB5 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB5 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM 370 380 390 400 410 420 490 pF1KB5 SMKIRPFFPQQ ::::::::::: NP_001 SMKIRPFFPQQ 430 >>NP_000500 (OMIM: 134850,202400,616004) fibrinogen gamm (437 aa) initn: 806 init1: 295 opt: 560 Z-score: 570.7 bits: 114.9 E(85289): 4.8e-25 Smith-Waterman score: 827; 33.2% identity (64.2% similar) in 400 aa overlap (95-487:34-415) 70 80 90 100 110 120 pF1KB5 PISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIR : : .: ::: : . . : . . NP_000 SLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQTKVD 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB5 NSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYID .... :.. .. : . .: : . .. .. ... . .... : .. .. . . NP_000 KDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYE 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB5 ETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQME-YCRTPCTVSCNIPVVSGKECEE .. .. ...: :. : .. .:: .:. : ::.: :. :: . .: ..::.:.. NP_000 ASILTH-DSSIRYLQEIYNSNNQKIVNLKEKV-AQLEAQCQEPCKDTVQIHDITGKDCQD 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB5 IIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGF : ::.. : .:.:.: .. . . :::... ..::::.:.: :::::: ..: ::.:: NP_000 IANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGF 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB5 GNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG--PTELLIEMEDWKGDKVKAHYGGFTV :... . : . :.::::.:: .. .. : : .:.:::.: : :. : : NP_000 GHLSPT--GTT------EFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKV 250 260 270 280 290 370 380 390 400 410 pF1KB5 QNEANKYQISVNKYRG-TAGNALMDGASQLMGEN---RTMTIHNGMFFSTYDRDNDGWLT ::.::... . : ::.:. :: . .:.. . .: :::: :::.: ::: . NP_000 GPEADKYRLTYAYFAGGDAGDAF-DGFD--FGDDPSDKFFTSHNGMQFSTWDNDNDKF-- 300 310 320 330 340 420 430 440 450 460 470 pF1KB5 SDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSM . .:...::.:::.:.:::.. :: :: :: :. . .: :.:..: .:: :::: NP_000 ---EGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSM 350 360 370 380 390 400 480 490 pF1KB5 RKMSMKIRPFFPQQ .: .::: :: NP_000 KKTTMKIIPFNRLTIGEGQQHHLGGAKQAGDV 410 420 430 >>NP_068656 (OMIM: 134850,202400,616004) fibrinogen gamm (453 aa) initn: 779 init1: 295 opt: 560 Z-score: 570.4 bits: 114.9 E(85289): 4.9e-25 Smith-Waterman score: 827; 33.2% identity (64.2% similar) in 400 aa overlap (95-487:34-415) 70 80 90 100 110 120 pF1KB5 PISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIR : : .: ::: : . . : . . NP_068 SLHPRNLILYFYALLFLSSTCVAYVATRDNCCILDERFGSYCPTTCGIADFLSTYQTKVD 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB5 NSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYID .... :.. .. : . .: : . .. .. ... . .... : .. .. . . NP_068 KDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYE 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB5 ETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQME-YCRTPCTVSCNIPVVSGKECEE .. .. ...: :. : .. .:: .:. : ::.: :. :: . .: ..::.:.. NP_068 ASILTH-DSSIRYLQEIYNSNNQKIVNLKEKV-AQLEAQCQEPCKDTVQIHDITGKDCQD 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB5 IIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGF : ::.. : .:.:.: .. . . :::... ..::::.:.: :::::: ..: ::.:: NP_068 IANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGF 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB5 GNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG--PTELLIEMEDWKGDKVKAHYGGFTV :... . : . :.::::.:: .. .. : : .:.:::.: : :. : : NP_068 GHLSPT--GTT------EFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKV 250 260 270 280 290 370 380 390 400 410 pF1KB5 QNEANKYQISVNKYRG-TAGNALMDGASQLMGEN---RTMTIHNGMFFSTYDRDNDGWLT ::.::... . : ::.:. :: . .:.. . .: :::: :::.: ::: . NP_068 GPEADKYRLTYAYFAGGDAGDAF-DGFD--FGDDPSDKFFTSHNGMQFSTWDNDNDKF-- 300 310 320 330 340 420 430 440 450 460 470 pF1KB5 SDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSM . .:...::.:::.:.:::.. :: :: :: :. . .: :.:..: .:: :::: NP_068 ---EGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSM 350 360 370 380 390 400 480 490 pF1KB5 RKMSMKIRPFFPQQ .: .::: :: NP_068 KKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL 410 420 430 440 450 >>XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen-like (282 aa) initn: 575 init1: 162 opt: 338 Z-score: 348.8 bits: 73.2 E(85289): 1.1e-12 Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:7-279) 170 180 190 200 210 220 pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR .:.:.. ... . ::..: .. .:. XP_016 MRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG 10 20 30 230 240 250 260 270 280 pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV :: : . : .. : ::. : . : .: :.: .: . ::::: ...::::: XP_016 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL :: :.::: .:.: : :..::: :. ::::::: .. :: . : XP_016 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK 100 110 120 130 140 350 360 370 380 390 400 pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN :.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :. XP_016 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ 150 160 170 180 190 200 410 420 430 440 450 460 pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT : :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: : XP_016 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T 210 220 230 240 470 480 490 pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ :.:.::..:.: :::.... ::::: :.: XP_016 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 250 260 270 280 >>XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen-like (312 aa) initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12 Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309) 170 180 190 200 210 220 pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR .:.:.. ... . ::..: .. .:. XP_016 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV :: : . : .. : ::. : . : .: :.: .: . ::::: ...::::: XP_016 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL :: :.::: .:.: : :..::: :. ::::::: .. :: . : XP_016 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK 130 140 150 160 170 350 360 370 380 390 400 pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN :.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :. XP_016 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ 180 190 200 210 220 230 410 420 430 440 450 460 pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT : :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: : XP_016 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T 240 250 260 270 470 480 490 pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ :.:.::..:.: :::.... ::::: :.: XP_016 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 280 290 300 310 >>NP_963847 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12 Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309) 170 180 190 200 210 220 pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR .:.:.. ... . ::..: .. .:. NP_963 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV :: : . : .. : ::. : . : .: :.: .: . ::::: ...::::: NP_963 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL :: :.::: .:.: : :..::: :. ::::::: .. :: . : NP_963 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK 130 140 150 160 170 350 360 370 380 390 400 pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN :.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :. NP_963 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ 180 190 200 210 220 230 410 420 430 440 450 460 pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT : :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: : NP_963 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T 240 250 260 270 470 480 490 pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ :.:.::..:.: :::.... ::::: :.: NP_963 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 280 290 300 310 >>NP_963846 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12 Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309) 170 180 190 200 210 220 pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR .:.:.. ... . ::..: .. .:. NP_963 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV :: : . : .. : ::. : . : .: :.: .: . ::::: ...::::: NP_963 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL :: :.::: .:.: : :..::: :. ::::::: .. :: . : NP_963 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK 130 140 150 160 170 350 360 370 380 390 400 pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN :.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :. NP_963 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ 180 190 200 210 220 230 410 420 430 440 450 460 pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT : :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: : NP_963 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T 240 250 260 270 470 480 490 pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ :.:.::..:.: :::.... ::::: :.: NP_963 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 280 290 300 310 >>NP_671736 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12 Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309) 170 180 190 200 210 220 pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR .:.:.. ... . ::..: .. .:. NP_671 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV :: : . : .. : ::. : . : .: :.: .: . ::::: ...::::: NP_671 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL :: :.::: .:.: : :..::: :. ::::::: .. :: . : NP_671 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK 130 140 150 160 170 350 360 370 380 390 400 pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN :.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :. NP_671 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ 180 190 200 210 220 230 410 420 430 440 450 460 pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT : :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: : NP_671 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T 240 250 260 270 470 480 490 pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ :.:.::..:.: :::.... ::::: :.: NP_671 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 280 290 300 310 >>NP_004458 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 575 init1: 162 opt: 338 Z-score: 348.2 bits: 73.2 E(85289): 1.2e-12 Smith-Waterman score: 657; 39.0% identity (65.7% similar) in 300 aa overlap (195-489:37-309) 170 180 190 200 210 220 pF1KB5 NENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCR .:.:.. ... . ::..: .. .:. NP_004 FILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKG 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB5 TPCTVSCNIPVVSGKE---CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTV :: : . : .. : ::. : . : .: :.: .: . ::::: ...::::: NP_004 DENTV---IDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTV 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB5 IQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELL :: :.::: .:.: : :..::: :. ::::::: .. :: . : NP_004 IQRRSDGSENFNRGWKDYENGFG---------NFVQKHGEYWLGNKNLHFLTTQEDYTLK 130 140 150 160 170 350 360 370 380 390 400 pF1KB5 IEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN :.. :.. .. :.: .: : .: : :......: ::::..: :... : . . :. NP_004 IDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQ 180 190 200 210 220 230 410 420 430 440 450 460 pF1KB5 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT : :::.:::.:.. . .:..:: .:::.::::.:: :: :: .: :: :: : NP_004 RMKFSTWDRDHDNY-----EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--T 240 250 260 270 470 480 490 pF1KB5 DDGVVWMNWKGSWYSMRKMSMKIRP--FFPQQ :.:.::..:.: :::.... ::::: :.: NP_004 DNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 280 290 300 310 491 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:33:04 2016 done: Sat Nov 5 16:33:06 2016 Total Scan time: 9.950 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]