Result of FASTA (ccds) for pF1KB5868
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5868, 493 aa
  1>>>pF1KB5868 493 - 493 aa - 493 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1922+/-0.00115; mu= 15.8841+/- 0.069
 mean_var=163.3310+/-31.197, 0's: 0 Z-trim(107.9): 184  B-trim: 0 in 0/53
 Lambda= 0.100355
 statistics sampled from 9699 (9897) to 9699 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.304), width:  16
 Scan time:  2.460

The best scores are:                                      opt bits E(32554)
CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2          ( 493) 3505 520.0 2.2e-147
CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11        ( 443) 1550 236.9 3.4e-62
CCDS9898.1 FBLN5 gene_id:10516|Hs108|chr14         ( 448) 1304 201.3 1.8e-51
CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3          (1184)  865 138.3 4.4e-32
CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3          (1231)  865 138.3 4.5e-32
CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11          (1256)  652 107.5 8.8e-23
CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11         (1303)  652 107.5   9e-23
CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5           (2912)  632 105.1 1.1e-21
CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19         (1557)  620 103.0 2.5e-21
CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19         (1587)  620 103.0 2.5e-21
CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19         (1624)  620 103.0 2.6e-21
CCDS32232.1 FBN1 gene_id:2200|Hs108|chr15          (2871)  621 103.5 3.3e-21
CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2          (1342)  585 97.8 7.7e-20
CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2          (1353)  585 97.8 7.7e-20
CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2          (1395)  585 97.8 7.8e-20
CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2          (1721)  585 98.0 8.9e-20
CCDS41237.1 MEGF6 gene_id:1953|Hs108|chr1          (1541)  534 90.5 1.4e-17
CCDS14067.1 FBLN1 gene_id:2192|Hs108|chr22         ( 703)  523 88.5 2.6e-17
CCDS43028.1 FBLN1 gene_id:2192|Hs108|chr22         ( 566)  515 87.2   5e-17
CCDS14068.1 FBLN1 gene_id:2192|Hs108|chr22         ( 601)  515 87.3 5.2e-17
CCDS14069.1 FBLN1 gene_id:2192|Hs108|chr22         ( 683)  515 87.3 5.7e-17
CCDS14048.1 SCUBE1 gene_id:80274|Hs108|chr22       ( 988)  502 85.6 2.6e-16
CCDS44864.1 NELL2 gene_id:4753|Hs108|chr12         ( 815)  470 80.9 5.8e-15
CCDS8746.1 NELL2 gene_id:4753|Hs108|chr12          ( 816)  470 80.9 5.8e-15
CCDS53781.1 NELL2 gene_id:4753|Hs108|chr12         ( 839)  470 80.9 5.9e-15
CCDS44863.1 NELL2 gene_id:4753|Hs108|chr12         ( 866)  470 80.9   6e-15
CCDS2923.1 PROS1 gene_id:5627|Hs108|chr3           ( 676)  465 80.1 8.5e-15
CCDS73268.1 NELL1 gene_id:4745|Hs108|chr11         ( 753)  456 78.8 2.2e-14
CCDS13149.1 CD93 gene_id:22918|Hs108|chr20         ( 652)  455 78.6 2.3e-14
CCDS7855.1 NELL1 gene_id:4745|Hs108|chr11          ( 810)  456 78.9 2.3e-14
CCDS73267.1 NELL1 gene_id:4745|Hs108|chr11         ( 838)  456 78.9 2.4e-14
CCDS12196.1 FBN3 gene_id:84467|Hs108|chr19         (2809)  459 80.0 3.8e-14
CCDS8002.1 VWCE gene_id:220001|Hs108|chr11         ( 955)  448 77.8 5.8e-14
CCDS908.1 NOTCH2 gene_id:4853|Hs108|chr1           (2471)  453 79.0 6.3e-14
CCDS7797.2 SCUBE2 gene_id:57758|Hs108|chr11        ( 971)  411 72.5 2.4e-12
CCDS43905.1 NOTCH1 gene_id:4851|Hs108|chr9         (2555)  416 73.7 2.7e-12
CCDS45072.1 GAS6 gene_id:2621|Hs108|chr13          ( 678)  406 71.5 3.2e-12
CCDS9831.1 LTBP2 gene_id:4053|Hs108|chr14          (1821)  408 72.4 4.8e-12
CCDS12326.1 NOTCH3 gene_id:4854|Hs108|chr19        (2321)  409 72.6   5e-12
CCDS44555.1 NELL1 gene_id:4745|Hs108|chr11         ( 763)  391 69.4 1.5e-11
CCDS13112.1 JAG1 gene_id:182|Hs108|chr20           (1218)  390 69.5 2.3e-11
CCDS53599.1 SCUBE2 gene_id:57758|Hs108|chr11       ( 807)  384 68.4 3.2e-11
CCDS81553.1 SCUBE2 gene_id:57758|Hs108|chr11       ( 999)  384 68.6 3.7e-11


>>CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2               (493 aa)
 initn: 3505 init1: 3505 opt: 3505  Z-score: 2759.4  bits: 520.0 E(32554): 2.2e-147
Smith-Waterman score: 3505; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)

               10        20        30        40        50        60
pF1KB5 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 CVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 SAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 THNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 PGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 SSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 PRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 NTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSS
              430       440       450       460       470       480

              490   
pF1KB5 VLRLTIIVGPFSF
       :::::::::::::
CCDS18 VLRLTIIVGPFSF
              490   

>>CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11             (443 aa)
 initn: 1790 init1: 692 opt: 1550  Z-score: 1230.2  bits: 236.9 E(32554): 3.4e-62
Smith-Waterman score: 1793; 50.0% identity (70.6% similar) in 494 aa overlap (1-493:13-443)

                           10        20        30        40        
pF1KB5             MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDEC
                   .: ::.: .:  :  . ::.::  .::.:::::::::  :.:.:..::
CCDS81 MLPCASCLPGSLLLWALLLLLLGSA--SPQDSEEPDSYTECTDGYEWDPDSQHCRDVNEC
               10        20          30        40        50        

       50        60        70        80        90       100        
pF1KB5 DIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMA
         .:.:::: :::.::::::::::..: .:  :.                          
CCDS81 LTIPEACKGEMKCINHYGGYLCLPRSAAVI--ND--------------------------
       60        70        80          90                          

      110       120       130       140       150       160        
pF1KB5 TSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEH
           : :           ::              :. : . : ::     :  ::: ...
CCDS81 ----LHG----------EGPP------------PPVPPAQHP-NP-----CPPGYEPDDQ
                                        100             110        

      170       180       190       200       210       220        
pF1KB5 NVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRC
       . : :.:::. . :.:: .: : :: ::. : :: ::.: : .:::::::    ::..::
CCDS81 DSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYR-YCQHRC
      120       130       140       150       160       170        

      230       240       250       260       270       280        
pF1KB5 VNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSD
       :: :::: ::: :::::. :: .:::.:::: .  : :.:.:  :.:.:.:.:::::  :
CCDS81 VNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRD
       180       190       200       210       220       230       

      290       300       310       320       330       340        
pF1KB5 RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECET-TNECRED
        ..: :::::  :::::::.:.::::.::: ::::::.. .: ::::.:::. ...: : 
CCDS81 GFSCSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEA
       240       250       260       270       280       290       

       350       360       370       380       390       400       
pF1KB5 EMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVP
       . : :.:::.::   : : .::: . ::::.::.:: .::: :.:::..::.: :.::::
CCDS81 QTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVP
       300       310       320       330       340       350       

       410       420       430       440       450       460       
pF1KB5 SDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEM
       .:.::::::..: .. :.:.:..:: .:.::.:: . :::::::.. ..::::...::::
CCDS81 ADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEM
       360       370       380       390       400       410       

       470       480       490   
pF1KB5 LTVSSIGTFRTSSVLRLTIIVGPFSF
       .:..:. ..:.:::::::..:: ..:
CCDS81 VTMNSLMSYRASSVLRLTVFVGAYTF
       420       430       440   

>>CCDS9898.1 FBLN5 gene_id:10516|Hs108|chr14              (448 aa)
 initn: 1431 init1: 534 opt: 1304  Z-score: 1037.6  bits: 201.3 E(32554): 1.8e-51
Smith-Waterman score: 1445; 42.8% identity (65.1% similar) in 493 aa overlap (3-493:6-448)

                  10        20        30        40        50       
pF1KB5    MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKG
            . : .:.:.: : .  ...     .:::.:.. :    :: :::::  .:.::.:
CCDS98 MPGIKRILTVTILALCLPSPGNAQ-----AQCTNGFDLDRQSGQCLDIDECRTIPEACRG
               10        20             30        40        50     

        60        70        80        90       100       110       
pF1KB5 GMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGG
        : :::. :::::.:.:  .    . :   ..:               :   ::  :   
CCDS98 DMMCVNQNGGYLCIPRTNPVY---RGPY--SNPY--------------STPYSGPYP---
          60        70           80                        90      

       120       130       140       150       160       170       
pF1KB5 FVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDEC
         :.:  ...:.. :      : :    :          . :  ::...: : : :.:::
CCDS98 --AAAPPLSAPNYPT------ISR----P----------LICRFGYQMDESNQCVDVDEC
             100                 110                 120       130 

       180       190       200       210       220       230       
pF1KB5 TAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYC
       .. .:.:   :.::: .:...:.:  ::     ::.:::::    ::.: :.:.:::. :
CCDS98 ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYG-YCQQLCANVPGSYSC
             140       150       160       170        180       190

       240       250       260       270       280       290       
pF1KB5 QCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDE
        :.::: :  .. .: :.::: . : :.: : :  :::::.:. ::::  : ..: :.::
CCDS98 TCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDE
              200       210       220       230       240       250

       300       310       320        330       340        350     
pF1KB5 CRTSSYLCQYQCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETTNE-CREDEMCWNYHG
       :  : .:::..:::.:: . : :: :: ..  .:.::::::::  :. :  .. :.: .:
CCDS98 CSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQG
              260       270       280       290       300       310

         360       370       380       390       400       410     
pF1KB5 GFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQA
       ::.:     :..::.   .:::.::. :  ::. : .:.:. :.. : ::::.::::.::
CCDS98 GFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQA
              320       330       340       350       360       370

         420       430       440       450       460       470     
pF1KB5 TTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGT
       :: : ..   :.::::::. :::.:::.:.:: ::... ..::::  .::::.::... .
CCDS98 TTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMITVNTVIN
              380       390       400       410       420       430

         480       490   
pF1KB5 FRTSSVLRLTIIVGPFSF
       :: :::.:: : :. . :
CCDS98 FRGSSVIRLRIYVSQYPF
              440        

>>CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3               (1184 aa)
 initn: 349 init1: 194 opt: 865  Z-score: 689.4  bits: 138.3 E(32554): 4.4e-32
Smith-Waterman score: 911; 32.5% identity (58.1% similar) in 465 aa overlap (29-467:704-1160)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     :  ::       .:.::.::     .:. :
CCDS46 PLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRG
           680       690       700       710       720       730   

       60        70           80        90       100               
pF1KB5 MKCVNHYGGYLC---LPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMAT------
        .:::  :.. :   :       ... . ..  . : ::     : .  .. ..      
CCDS46 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR
           740       750       760       770       780       790   

         110         120       130       140       150       160   
pF1KB5 ----SGVL--PGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGY
           .: :  : :. :     ..  :    : .:    : .       ::   . :: ::
CCDS46 QRCMDGFLQDPEGNCVDINECTSLSE--PCRPGFSCI-NTVGSYTCQRNP---LICARGY
           800       810         820        830       840          

           170        180       190       200         210       220
pF1KB5 EQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDECTI
       . :. .. : :..:: .:.: :   ::: :: ::. :.:  :.:.   :. :.:..::  
CCDS46 HASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA
       850       860       870       880       890       900       

                230       240       250       260       270        
pF1KB5 PP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQ
        :   :.. : :: ::. :.:. :: :::..  : :.:::.:. .:.:.: :: ::. : 
CCDS46 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSYQCY
       910       920       930       940       950        960      

      280       290        300       310       320         330     
pF1KB5 CNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGYQVVRS-RTCQDI
       : :::.:. :  .: ::::: . .. :: ..:.: ::...: :: ::: .. . :.:.:.
CCDS46 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV
        970       980       990      1000      1010      1020      

         340        350       360       370       380         390  
pF1KB5 NECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRELPQS
       .::   :..: : : : : .:.:::  :  :   :. . ...:   . . .  :.. :  
CCDS46 DECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNSPAR
       1030      1040      1050       1060      1070      1080     

            400       410       420       430       440       450  
pF1KB5 IVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLV
       :..  .....   ::. ::.:  .  ...   .. : .:::.: :  :. .  .... : 
CCDS46 ITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQ
        1090      1100      1110      1120      1130      1140     

            460       470       480       490   
pF1KB5 KSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
       ...  ::.  .:.::                          
CCDS46 RAVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL  
        1150      1160      1170      1180      

>>CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3               (1231 aa)
 initn: 349 init1: 194 opt: 865  Z-score: 689.2  bits: 138.3 E(32554): 4.5e-32
Smith-Waterman score: 925; 32.9% identity (58.7% similar) in 465 aa overlap (29-467:752-1207)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     :.:::  .  :. : ::.::     .:. :
CCDS46 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRG
             730       740       750       760        770       780

       60        70           80        90       100               
pF1KB5 MKCVNHYGGYLC---LPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMAT------
        .:::  :.. :   :       ... . ..  . : ::     : .  .. ..      
CCDS46 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR
              790       800       810       820       830       840

         110         120       130       140       150       160   
pF1KB5 ----SGVL--PGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGY
           .: :  : :. :     ..  :    : .:    : .       ::   . :: ::
CCDS46 QRCMDGFLQDPEGNCVDINECTSLSE--PCRPGFSCI-NTVGSYTCQRNP---LICARGY
              850       860         870        880          890    

           170        180       190       200         210       220
pF1KB5 EQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDECTI
       . :. .. : :..:: .:.: :   ::: :: ::. :.:  :.:.   :. :.:..::  
CCDS46 HASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA
          900       910       920       930       940       950    

                230       240       250       260       270        
pF1KB5 PP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQ
        :   :.. : :: ::. :.:. :: :::..  : :.:::.:. .:.:.: :: ::. : 
CCDS46 SPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSYQCY
          960       970       980       990       1000      1010   

      280       290        300       310       320         330     
pF1KB5 CNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGYQVVRS-RTCQDI
       : :::.:. :  .: ::::: . .. :: ..:.: ::...: :: ::: .. . :.:.:.
CCDS46 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV
          1020      1030      1040      1050      1060      1070   

         340        350       360       370       380         390  
pF1KB5 NECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CRELPQS
       .::   :..: : : : : .:.:::  :  :   :. . ...:   . . .  :.. :  
CCDS46 DECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNSPAR
          1080      1090       1100      1110      1120      1130  

            400       410       420       430       440       450  
pF1KB5 IVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLV
       :..  .....   ::. ::.:  .  ...   .. : .:::.: :  :. .  .... : 
CCDS46 ITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQ
           1140      1150      1160      1170      1180      1190  

            460       470       480       490   
pF1KB5 KSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
       ...  ::.  .:.::                          
CCDS46 RAVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL  
           1200      1210      1220      1230   

>>CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11               (1256 aa)
 initn: 397 init1: 281 opt: 652  Z-score: 522.4  bits: 107.5 E(32554): 8.8e-23
Smith-Waterman score: 652; 32.8% identity (51.9% similar) in 366 aa overlap (41-379:571-919)

               20        30        40        50        60        70
pF1KB5 TLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC
                                     :  . ::: .  . :  : .::     : :
CCDS81 ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHG-ECVPGPPDYSC
              550       560       570       580        590         

                       80        90       100       110            
pF1KB5 L--------PKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSG----VLPGGGF
                :.    .  ::   .   :..:    : :  . .   . :    :  ::  
CCDS81 HCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG--SYNCHCNRGYRLHVGAGGRS
     600       610       620       630         640       650       

      120       130       140       150        160         170     
pF1KB5 VASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSH-RIQCAAGY--EQSEHNVCQDID
        ..    : :..  : ..: :           . :.: . .:  ::  . :.  ::.:::
CCDS81 CVDLNECAKPHL-CGDGGFCI-----------NFPGHYKCNCYPGYRLKASRPPVCEDID
       660        670                  680       690       700     

         180       190        200       210        220        230  
pF1KB5 ECTAGTHNCRADQVCINLRGSFAC-QCPPGYQKRGE-QCVDIDECTIPPYCHQR-CVNTP
       ::   . .:  :  : :  ::: :  : :::...:   : :..::.    :    : : :
CCDS81 ECRDPS-SC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLP
         710         720       730       740       750       760   

            240       250       260        270       280       290 
pF1KB5 GSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ-CYNILGSFICQCNQGYELSSDRLN
       ::: : :. :.  : .. .:.:..::.:.. : .  : :  ::: ::: .::.:: :: .
CCDS81 GSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
           770       780       790       800       810       820   

             300       310       320       330        340       350
pF1KB5 CEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINEC-ETTNECREDEMC
       :::::::   .     .:.:  :.. :.::::...: .: ::::.:: .  . :     :
CCDS81 CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGAC
           830       840       850       860       870       880   

              360              370       380       390       400   
pF1KB5 WNYHGGFRCY---PRNPCQDPY----ILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSD
        : .:.. :      .: :: .    .  :...  :                        
CCDS81 KNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECC
           890       900       910       920       930       940   

           410       420       430       440       450       460   
pF1KB5 RSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIV
                                                                   
CCDS81 CSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
           950       960       970       980       990      1000   

>>CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11              (1303 aa)
 initn: 281 init1: 281 opt: 652  Z-score: 522.3  bits: 107.5 E(32554): 9e-23
Smith-Waterman score: 652; 32.8% identity (51.9% similar) in 366 aa overlap (41-379:571-919)

               20        30        40        50        60        70
pF1KB5 TLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC
                                     :  . ::: .  . :  : .::     : :
CCDS44 ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHG-ECVPGPPDYSC
              550       560       570       580        590         

                       80        90       100       110            
pF1KB5 L--------PKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSG----VLPGGGF
                :.    .  ::   .   :..:    : :  . .   . :    :  ::  
CCDS44 HCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGG--SYNCHCNRGYRLHVGAGGRS
     600       610       620       630         640       650       

      120       130       140       150        160         170     
pF1KB5 VASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSH-RIQCAAGY--EQSEHNVCQDID
        ..    : :..  : ..: :           . :.: . .:  ::  . :.  ::.:::
CCDS44 CVDLNECAKPHL-CGDGGFCI-----------NFPGHYKCNCYPGYRLKASRPPVCEDID
       660        670                  680       690       700     

         180       190        200       210        220        230  
pF1KB5 ECTAGTHNCRADQVCINLRGSFAC-QCPPGYQKRGE-QCVDIDECTIPPYCHQR-CVNTP
       ::   . .:  :  : :  ::: :  : :::...:   : :..::.    :    : : :
CCDS44 ECRDPS-SC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLP
         710         720       730       740       750       760   

            240       250       260        270       280       290 
pF1KB5 GSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQ-CYNILGSFICQCNQGYELSSDRLN
       ::: : :. :.  : .. .:.:..::.:.. : .  : :  ::: ::: .::.:: :: .
CCDS44 GSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH
           770       780       790       800       810       820   

             300       310       320       330        340       350
pF1KB5 CEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINEC-ETTNECREDEMC
       :::::::   .     .:.:  :.. :.::::...: .: ::::.:: .  . :     :
CCDS44 CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGAC
           830       840       850       860       870       880   

              360              370       380       390       400   
pF1KB5 WNYHGGFRCY---PRNPCQDPY----ILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSD
        : .:.. :      .: :: .    .  :...  :                        
CCDS44 KNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECC
           890       900       910       920       930       940   

           410       420       430       440       450       460   
pF1KB5 RSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIV
                                                                   
CCDS44 CSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE
           950       960       970       980       990      1000   

>>CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5                (2912 aa)
 initn: 1323 init1: 333 opt: 632  Z-score: 502.7  bits: 105.1 E(32554): 1.1e-21
Smith-Waterman score: 712; 31.3% identity (53.8% similar) in 431 aa overlap (29-431:1185-1584)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     :  :.: .: :..: ::.::..  . :..:
CCDS34 NCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG
         1160      1170      1180      1190      1200      1210    

       60        70        80        90       100       110        
pF1KB5 MKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGF
        ::::  : : :         . .   : :   .: .     ..  ..  :. .   :..
CCDS34 -KCVNMIGTYQC---------SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY
          1220               1230      1240      1250      1260    

      120       130          140         150        160        170 
pF1KB5 VASAAAVAGPEMQTGRNNFVI---RRNP--ADPQRIPSNPS-HRIQCAAGYEQS-EHNVC
         : .  .   :  ::.   :   . ::   :  .  . :. .:  :  :.  : . ..:
CCDS34 ECSCSE-GYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC
         1270       1280      1290      1300      1310      1320   

             180       190       200        210        220         
pF1KB5 QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ-KRGEQ-CVDIDECTIPPY-C--HQ
        :..::  ... :   . : : .::: :.:  ::. :.:   :.:.::: :  . :  : 
CCDS34 IDVNECDLNSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHA
          1330      1340       1350      1360      1370      1380  

        230       240       250        260         270       280   
pF1KB5 RCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCA--QQCYNILGSFICQCNQGY
        :.: :::: :.:  :.   .:.  :.:..:: ....::.   :: :  ::. : :..:.
CCDS34 SCLNIPGSFKCSCREGW--IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF
           1390        1400      1410      1420      1430      1440

           290       300        310       320        330       340 
pF1KB5 ELSSDRLNCEDIDECRTSSYLCQY-QCVNEPGKFSCMCPQGYQVVR-SRTCQDINECETT
         ..: ..: :.:::  .  ::.  ::.: :: . : : .:.  .  ::.::::.::   
CCDS34 --TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQ
               1450      1460      1470      1480      1490        

             350       360       370              380         390  
pF1KB5 NECREDEMCWNYHGGFRCYPRNPCQDPYIL-------TPENRCVCPVS--NAMCRELPQS
       : :     : :  : :.:     :.: : :       :  ..:. :..  :..: . :  
CCDS34 NICVFGT-CNNLPGMFHCI----CDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPG-
     1500       1510          1520      1530      1540      1550   

            400       410         420       430       440       450
pF1KB5 IVYKYMSIRSDRSVPSDIFQIQATTI--YANTINTFRIKSGNENGEFYLRQTSPVSAMLV
               : . . : : ::.. : .    : ...  .: :                   
CCDS34 --------RYECNCPPD-FQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSR
                   1560       1570      1580      1590      1600   

              460       470       480       490                    
pF1KB5 LVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF                 
                                                                   
CCDS34 SSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQG
          1610      1620      1630      1640      1650      1660   

>--
 initn: 1323 init1: 333 opt: 632  Z-score: 502.7  bits: 105.1 E(32554): 1.1e-21
Smith-Waterman score: 650; 30.4% identity (55.8% similar) in 342 aa overlap (43-378:2448-2734)

             20        30        40        50        60        70  
pF1KB5 ALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLP
                                     .::::: ..:. : .: .:.: .:.. :. 
CCDS34 WGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRCFC
      2420      2430      2440      2450      2460       2470      

             80        90       100       110       120       130  
pF1KB5 KTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQT
       :.                     : :: . ..: .  .                .:.   
CCDS34 KV---------------------GYTTDISGTSCIDLD------------ECSQSPKP--
                            2480      2490                  2500   

            140       150       160        170       180       190 
pF1KB5 GRNNFVIRRNPADPQRIPSNPSHRIQCAAGYE-QSEHNVCQDIDECTAGTHNCRADQVCI
          :.. .          .. :.. .:  ::  : . ..:.:.::: .  :::.   .:.
CCDS34 --CNYICKN---------TEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCV
                       2510      2520      2530      2540          

             200       210        220         230       240        
pF1KB5 NLRGSFACQCPPGYQKRGEQCVDIDEC-TIPPYCHQR--CVNTPGSFYCQCSPGFQLAAN
       :  :.:.:.::::. ..   :.: .:: . :  :  .  : :::::: :.:. ::.: :.
CCDS34 NTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDAT
     2550      2560      2570      2580      2590      2600        

      250       260       270       280       290       300        
pF1KB5 NYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ
       . .: :..:::....: . : ::::.. : : :::    .  .: : .:: . .   . .
CCDS34 GLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSAS
     2610      2620      2630      2640      2650      2660        

      310       320        330       340        350       360      
pF1KB5 CVNEPGKFSCMCPQGYQVVR-SRTCQDINECETT-NECREDEMCWNYHGGFRCYPRNPCQ
       : :  :...: ::.:..  . : .:.:.::: .. : :  .  : : .::. :     : 
CCDS34 CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPC--NYGCSNTEGGYLC----GCP
     2670      2680      2690      2700        2710          2720  

        370       380       390       400       410       420      
pF1KB5 DPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTF
         :  . ...::                                                
CCDS34 PGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGYSKKDSRQKRSIH
           2730      2740      2750      2760      2770      2780  

>--
 initn: 497 init1: 182 opt: 557  Z-score: 444.0  bits: 94.2 E(32554): 2.1e-18
Smith-Waterman score: 634; 31.2% identity (54.9% similar) in 381 aa overlap (28-392:1676-2026)

                  10        20        30        40        50       
pF1KB5    MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKG
                                     .: .::  .   . :.:::::   : .:  
CCDS34 IILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGP
        1650      1660      1670      1680      1690      1700     

        60        70        80           90       100       110    
pF1KB5 GMKCVNHYGGYLCLPKTAQIIVN---NEQPQQETQPAEGTSGATTGVVAASSMATSGVLP
       :  : :  :.: :.     . ::   : . ....   .. .:.:            . ::
CCDS34 GT-CYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC----------ENELP
         1710      1720      1730      1740                1750    

          120       130       140       150       160          170 
pF1KB5 GGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAA--GYEQSEHN-VC
          : ..        ...:.       .: .:   :.. . .  :.   :.  . :.   
CCDS34 ---FNVTKRMCCCT-YNVGKA----WNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKA
            1760       1770          1780      1790      1800      

             180       190       200       210         220         
pF1KB5 QDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQ--CVDIDECTIPPYCHQR--
        :::::      : :. ::::  ::: :.:: :..       : :::::.      ::  
CCDS34 VDIDECKEIPGIC-ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNA
       1810       1820      1830      1840      1850      1860     

        230       240       250        260        270       280    
pF1KB5 -CVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASNQCAQQ-CYNILGSFICQCNQGYE
        :.:.:::. :.:. ::.:. :. .::: ::: .  : :..  : .. ::. : :..:..
CCDS34 DCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFK
        1870      1880       1890      1900      1910      1920    

          290       300        310       320       330       340   
pF1KB5 LSSDRLNCEDIDECRTSSYLC-QYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETT--
        :.:.  : :.:::.     : .  : :  :...:.:  :......  : ::.:: .   
CCDS34 ASQDQTMCMDVDECERHP--CGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFG
         1930      1940        1950      1960      1970      1980  

             350       360       370       380       390       400 
pF1KB5 NECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIR
       . ::. . :.:  :.:.:     :.. : :::...  : ...  :  :: :         
CCDS34 QVCRNGR-CFNEIGSFKCL----CNEGYELTPDGKN-C-IDTNECVALPGSCSPGTCQNL
            1990      2000          2010        2020      2030     

             410       420       430       440       450       460 
pF1KB5 SDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREH
                                                                   
CCDS34 EGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRR
        2040      2050      2060      2070      2080      2090     

>--
 initn: 510 init1: 263 opt: 556  Z-score: 443.3  bits: 94.1 E(32554): 2.3e-18
Smith-Waterman score: 605; 32.0% identity (53.7% similar) in 378 aa overlap (29-387:2043-2396)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     :  :::     ..: ::.:::  :. :  :
CCDS34 NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKS--ENCIDINECDEDPNICLFG
           2020      2030      2040      2050        2060      2070

       60        70        80        90       100       110        
pF1KB5 MKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGF
        .:.:  ::. ::   . .. .: .   .:. .   ..  .:  .. .          .:
CCDS34 -SCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPK----------AF
              2080      2090      2100      2110                   

      120       130       140        150         160         170   
pF1KB5 VASAAAVAGPEMQTGRNNFVIRRNPADPQRI-PSNPSHRIQ--CAAGYEQ--SEHNVCQD
        .. :     .:  :..        .:: .. :..    .:  :  :.    : :.. .:
CCDS34 NTTKAKCCCSKMP-GEGW-------GDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTRED
    2120      2130              2140      2150      2160      2170 

           180       190       200         210       220        230
pF1KB5 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGEQCVDIDECTIPPYC-HQRCVN
       ..::  .   :   : :::  ::: :.:: ::.    : .::: :::.:   : .  :.:
CCDS34 VNECLESPGICSNGQ-CINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTN
            2180       2190      2200      2210      2220      2230

              240       250       260         270       280        
pF1KB5 TPGSFYCQCSPGFQLAANNYTCVDINECDASNQ--CAQQCYNILGSFICQCNQGYELSSD
       . ::: :.:. ::.  .  ..: ::::: :.:   :: .:.: .::. : :  :: :  :
CCDS34 VIGSFECNCNEGFE-PGPMMNCEDINEC-AQNPLLCAFRCMNTFGSYECTCPIGYALRED
             2240       2250       2260      2270      2280        

      290       300          310       320        330       340    
pF1KB5 RLNCEDIDECRTSSYLCQ---YQCVNEPGKFSCMCPQGY-QVVRSRTCQDINECETTNEC
       .  :.:.:::  . . :.   ..: :  : : :.:: :. .   .. : : :::.:    
CCDS34 QKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGI
     2290      2300      2310      2320      2330      2340        

          350       360       370            380       390         
pF1KB5 REDEMCWNYHGGFRCYPRNPCQDPYILTP--ENR---CVCPVSNAMCRELPQSIVYKYMS
        :.  : :  :..::   .  :.    :   .::   :   : ...:.            
CCDS34 CENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKS
     2350      2360      2370      2380      2390      2400        

     400       410       420       430       440       450         
pF1KB5 IRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPR
                                                                   
CCDS34 ECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINT
     2410      2420      2430      2440      2450      2460        

>--
 initn: 528 init1: 239 opt: 526  Z-score: 419.8  bits: 89.7 E(32554): 4.6e-17
Smith-Waterman score: 563; 28.8% identity (50.1% similar) in 389 aa overlap (29-386:643-1003)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     :  :.   :  . : :.:::. .:  : .:
CCDS34 KNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ-TPGICMNG
            620       630       640       650       660        670 

       60        70         80        90       100       110       
pF1KB5 MKCVNHYGGYLC-LPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGG
        .:.:  :.. :  :    . ....   .  . .   .:   :: .         .::. 
CCDS34 -HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRP-------FPGA-
              680       690       700       710              720   

       120       130       140       150       160       170       
pF1KB5 FVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDEC
        . :    :.:..  :.        : .:    ..   .  :..:   .  .  .::.::
CCDS34 VTKSECCCANPDYGFGE--------PCQPCPAKNSAEFHGLCSSGVGITVDG--RDINEC
            730               740       750       760         770  

       180       190       200         210       220         230   
pF1KB5 TAGTHNCRADQVCINLRGSFACQCPPGYQK--RGEQCVDIDECTIPPY-CHQR-CVNTPG
       .     : :. .: :::::. :.:  ::.    :..:.::::: .    : .  : ::::
CCDS34 ALDPDIC-ANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPG
             780       790       800       810       820       830 

           240       250       260        270       280       290  
pF1KB5 SFYCQCSPGFQLAANNYTCVDINECDASNQCAQ-QCYNILGSFICQCNQGYELSSDRLNC
       :. : : ::. . ... :: :::::. :: :..  : : :::: :.:. : .:::  : :
CCDS34 SYSCTCPPGYVFRTETETCEDINECE-SNPCVNGACRNNLGSFNCECSPGSKLSSTGLIC
             840       850        860       870       880       890

            300                      310                 320       
pF1KB5 EDIDECRTSSYL------CQY---------QCVNEPG----------KFSCMCPQGYQVV
         ::  . . .:      :.          .:    :          ...  ::.:   .
CCDS34 --IDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARI
                900       910       920       930       940        

       330       340       350       360       370       380       
pF1KB5 RSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCR
       .. ::.:.::::.      .  : : .:.:.:     : .   :   .:    .   .: 
CCDS34 KGVTCEDVNECEVFPGVCPNGRCVNSKGSFHC----ECPEGLTLDGTGRVCLDIRMEQCY
      950       960       970       980           990      1000    

       390       400       410       420       430       440       
pF1KB5 ELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSA
                                                                   
CCDS34 LKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDV
         1010      1020      1030      1040      1050      1060    

>--
 initn: 618 init1: 219 opt: 465  Z-score: 372.1  bits: 80.9 E(32554): 2.1e-14
Smith-Waterman score: 536; 31.1% identity (54.2% similar) in 347 aa overlap (28-319:302-642)

                  10        20        30        40        50       
pF1KB5    MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKG
                                     .:  :.. . . :.:.:::::.:.:  :. 
CCDS34 GACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICET
             280       290       300       310       320       330 

        60        70                           80                  
pF1KB5 GMKCVNHYGGYLCLPKTAQI-------------------IVNN----EQPQQETQ-----
       : .: :  :.:.:.   . .                   .::.    : : . :.     
CCDS34 G-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCC
              340       350       360       370       380       390

       90              100       110       120       130       140 
pF1KB5 -PAE----GT---SGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRR
        :..    ::   .  . :      .  .: :: ::. .::..  :    :: :.:.   
CCDS34 EPGRCWGIGTIPEACPVRGSEEYRRLCMDG-LPMGGIPGSAGSRPGG---TGGNGFAPSG
              400       410       420        430          440      

                  150          160               170       180     
pF1KB5 N-----PADPQRIPSNPSHRIQ---CAAGYEQSEHN--------VCQDIDECTAGTHNCR
       :     :.    ::   .. ..    .::   . ..        . : :: :   .. : 
CCDS34 NGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCL
        450       460       470       480       490       500      

         190       200       210        220       230       240    
pF1KB5 ADQVCINLRGSFACQCPPGYQKRGE-QCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQ
         . ::   .:. :.:  ::.. .. .:.:.::::  :  .  :::::::.::.:  :::
CCDS34 NGR-CIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQ
         510       520       530       540       550       560     

          250       260         270       280       290       300  
pF1KB5 LAANNYTCVDINECDASN-QCAQ-QCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSS
        . .. .:.::.::  ..  : . .: :  ::: : :: :.::..:  :: : ::: :..
CCDS34 RTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTN
         570       580       590       600       610       620     

            310       320       330       340       350       360  
pF1KB5 YLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPR
       .  . .:.:: :.:.:.                                           
CCDS34 MCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCP
         630       640       650       660       670       680     

>>CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19              (1557 aa)
 initn: 618 init1: 195 opt: 620  Z-score: 496.4  bits: 103.0 E(32554): 2.5e-21
Smith-Waterman score: 646; 31.8% identity (50.6% similar) in 387 aa overlap (29-392:505-865)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     : .:.. .:   .: :.:::  ::  :  :
CCDS74 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG
          480       490       500       510       520       530    

       60        70                80            90       100      
pF1KB5 MKCVNHYGGYLCL--------PKTAQIIVNNE----QPQQETQPAEGTSGATTGVVAASS
        .: :  :.. :.        :..:. .  .:     :  .    :.: :.   :  :. 
CCDS74 -RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGY
           540       550       560       570       580       590   

        110       120       130       140       150       160      
pF1KB5 MATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQS
       .:.    : :.   ..   .      ::.           . .:.  : :  : ::.. :
CCDS74 QAA----PHGASCQDVDECTQSPGLCGRGAC---------KNLPG--SFRCVCPAGFRGS
               600       610       620                  630        

        170        180       190       200       210          220  
pF1KB5 EHNVCQ-DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--QCVDIDECT-IPP
          .:. :.:::.     :   . : :  ::: : :: :...::    : :.:::.  ::
CCDS74 ---ACEEDVDECAQEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP
         640       650        660       670       680       690    

             230       240       250       260        270          
pF1KB5 YC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQC-AQQCYNILGSFICQ-C
        : . :: :: ::: : :  :::  . .  : :..::.    : .:.: :  ::: :. :
CCDS74 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTC
          700       710       720       730       740       750    

     280       290       300         310       320       330       
pF1KB5 NQGYELSSDRLNCEDIDECRTSSYLC--QYQCVNEPGKFSCMCPQGYQVVRSRT--CQDI
        .:..:   :  : :.::: ...  :  . .:.:  :.: : :  ::..  .:   : :.
CCDS74 PSGHHLHRGR--CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV
          760         770       780       790       800       810  

         340       350       360       370       380       390     
pF1KB5 NECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVY
       :::   . :     : :  :.: :     :   :   :..     :..   ..: ::   
CCDS74 NECLEGDFCFPHGECLNTDGSFAC----TCAPGYRPGPRGASCLDVDECSEEDLCQSGIC
            820       830           840       850       860        

         400       410       420       430       440       450     
pF1KB5 KYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSL
                                                                   
CCDS74 TNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY
      870       880       890       900       910       920        

>>CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19              (1587 aa)
 initn: 618 init1: 195 opt: 620  Z-score: 496.3  bits: 103.0 E(32554): 2.5e-21
Smith-Waterman score: 646; 31.8% identity (50.6% similar) in 387 aa overlap (29-392:535-895)

                 10        20        30        40        50        
pF1KB5   MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGG
                                     : .:.. .:   .: :.:::  ::  :  :
CCDS74 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG
          510       520       530       540       550       560    

       60        70                80            90       100      
pF1KB5 MKCVNHYGGYLCL--------PKTAQIIVNNE----QPQQETQPAEGTSGATTGVVAASS
        .: :  :.. :.        :..:. .  .:     :  .    :.: :.   :  :. 
CCDS74 -RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGY
           570       580       590       600       610       620   

        110       120       130       140       150       160      
pF1KB5 MATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQS
       .:.    : :.   ..   .      ::.           . .:.  : :  : ::.. :
CCDS74 QAA----PHGASCQDVDECTQSPGLCGRGAC---------KNLPG--SFRCVCPAGFRGS
               630       640       650                  660        

        170        180       190       200       210          220  
pF1KB5 EHNVCQ-DIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGE--QCVDIDECT-IPP
          .:. :.:::.     :   . : :  ::: : :: :...::    : :.:::.  ::
CCDS74 ---ACEEDVDECAQEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP
         670       680        690       700       710       720    

             230       240       250       260        270          
pF1KB5 YC-HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQC-AQQCYNILGSFICQ-C
        : . :: :: ::: : :  :::  . .  : :..::.    : .:.: :  ::: :. :
CCDS74 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTC
          730       740       750       760       770       780    

     280       290       300         310       320       330       
pF1KB5 NQGYELSSDRLNCEDIDECRTSSYLC--QYQCVNEPGKFSCMCPQGYQVVRSRT--CQDI
        .:..:   :  : :.::: ...  :  . .:.:  :.: : :  ::..  .:   : :.
CCDS74 PSGHHLHRGR--CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV
          790         800       810       820       830       840  

         340       350       360       370       380       390     
pF1KB5 NECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVY
       :::   . :     : :  :.: :     :   :   :..     :..   ..: ::   
CCDS74 NECLEGDFCFPHGECLNTDGSFAC----TCAPGYRPGPRGASCLDVDECSEEDLCQSGIC
            850       860           870       880       890        

         400       410       420       430       440       450     
pF1KB5 KYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSL
                                                                   
CCDS74 TNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY
      900       910       920       930       940       950        




493 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:22:54 2016 done: Sat Nov  5 15:22:54 2016
 Total Scan time:  2.460 Total Display time:  0.110

Function used was FASTA [36.3.4 Apr, 2011]
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