FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5874, 494 aa 1>>>pF1KB5874 494 - 494 aa - 494 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.5901+/-0.000667; mu= -13.3072+/- 0.042 mean_var=554.0721+/-112.585, 0's: 0 Z-trim(118.6): 403 B-trim: 1939 in 2/56 Lambda= 0.054487 statistics sampled from 31189 (31632) to 31189 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.371), width: 16 Scan time: 10.730 The best scores are: opt bits E(85289) NP_005617 (OMIM: 601940) serine/arginine-rich spli ( 494) 3163 263.7 8.6e-70 XP_011540253 (OMIM: 601940) PREDICTED: serine/argi ( 464) 1728 150.9 7.5e-36 NP_006266 (OMIM: 601944) serine/arginine-rich spli ( 344) 1385 123.8 8e-28 XP_005268056 (OMIM: 600914) PREDICTED: serine/argi ( 271) 1027 95.5 2e-19 XP_005268057 (OMIM: 600914) PREDICTED: serine/argi ( 271) 1027 95.5 2e-19 XP_016877082 (OMIM: 600914) PREDICTED: serine/argi ( 271) 1027 95.5 2e-19 NP_008856 (OMIM: 600914) serine/arginine-rich spli ( 272) 1020 95.0 2.9e-19 NP_001307143 (OMIM: 600914) serine/arginine-rich s ( 272) 1020 95.0 2.9e-19 NP_001034554 (OMIM: 600914) serine/arginine-rich s ( 272) 1020 95.0 2.9e-19 XP_011535379 (OMIM: 600914) PREDICTED: serine/argi ( 239) 646 65.5 1.9e-10 NP_008855 (OMIM: 600812) serine/arginine-rich spli ( 248) 599 61.8 2.5e-09 XP_016877083 (OMIM: 600914) PREDICTED: serine/argi ( 145) 493 53.3 5.6e-07 NP_001071634 (OMIM: 600812) serine/arginine-rich s ( 201) 464 51.1 3.4e-06 XP_016864545 (OMIM: 609268) PREDICTED: splicing re ( 359) 438 49.4 2.1e-05 NP_001310463 (OMIM: 609268) splicing regulatory gl ( 359) 438 49.4 2.1e-05 NP_001310464 (OMIM: 609268) splicing regulatory gl ( 358) 436 49.2 2.3e-05 XP_011541473 (OMIM: 609268) PREDICTED: splicing re ( 508) 438 49.5 2.7e-05 NP_001310456 (OMIM: 609268) splicing regulatory gl ( 508) 438 49.5 2.7e-05 NP_631907 (OMIM: 609268) splicing regulatory gluta ( 508) 438 49.5 2.7e-05 XP_005247024 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 441 49.9 3e-05 NP_004783 (OMIM: 606093) peptidyl-prolyl cis-trans ( 754) 441 49.9 3e-05 XP_005247023 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 441 49.9 3e-05 NP_001257421 (OMIM: 609268) splicing regulatory gl ( 507) 436 49.4 3e-05 NP_001070667 (OMIM: 609268) splicing regulatory gl ( 624) 438 49.6 3.1e-05 XP_005255283 (OMIM: 606032) PREDICTED: serine/argi (2751) 455 51.6 3.4e-05 NP_057417 (OMIM: 606032) serine/arginine repetitiv (2752) 455 51.6 3.4e-05 NP_001310458 (OMIM: 609268) splicing regulatory gl ( 623) 436 49.4 3.4e-05 NP_003760 (OMIM: 601943) serine/arginine-rich spli ( 221) 414 47.2 5.6e-05 XP_016872631 (OMIM: 603269) PREDICTED: serine/argi ( 282) 394 45.8 0.0002 NP_115285 (OMIM: 603269) serine/arginine-rich spli ( 282) 394 45.8 0.0002 NP_001310462 (OMIM: 609268) splicing regulatory gl ( 538) 396 46.2 0.00027 XP_016879869 (OMIM: 614396) PREDICTED: G patch dom (1288) 389 46.1 0.00073 NP_001291869 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078 NP_001291871 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078 XP_016879867 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078 XP_016879866 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078 XP_016879865 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078 NP_001291872 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078 XP_016879864 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078 XP_016879868 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078 NP_001291870 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078 XP_016858323 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079 XP_016858319 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079 XP_016858320 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079 XP_016858321 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079 XP_016858322 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079 XP_011522860 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079 XP_016879862 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079 XP_016879861 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079 XP_011522861 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079 >>NP_005617 (OMIM: 601940) serine/arginine-rich splicing (494 aa) initn: 3163 init1: 3163 opt: 3163 Z-score: 1374.0 bits: 263.7 E(85289): 8.6e-70 Smith-Waterman score: 3163; 99.8% identity (100.0% similar) in 494 aa overlap (1-494:1-494) 10 20 30 40 50 60 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RSKKEKSRSPSKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 430 440 450 460 470 480 490 pF1KB5 RSPSRSRSRSHSRS :::::::::::::: NP_005 RSPSRSRSRSHSRS 490 >>XP_011540253 (OMIM: 601940) PREDICTED: serine/arginine (464 aa) initn: 2125 init1: 1719 opt: 1728 Z-score: 764.7 bits: 150.9 E(85289): 7.5e-36 Smith-Waterman score: 2909; 93.7% identity (93.9% similar) in 494 aa overlap (1-494:1-464) 10 20 30 40 50 60 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS :::::::::::::: :::::::::::::::: XP_011 RRRSYSRSRSHSRS------------------------------GSRSRSKSRSRSQSRS 190 200 210 250 260 270 280 290 300 pF1KB5 RSKKEKSRSPSKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 400 410 420 430 440 450 490 pF1KB5 RSPSRSRSRSHSRS :::::::::::::: XP_011 RSPSRSRSRSHSRS 460 >>NP_006266 (OMIM: 601944) serine/arginine-rich splicing (344 aa) initn: 841 init1: 841 opt: 1385 Z-score: 620.5 bits: 123.8 E(85289): 8e-28 Smith-Waterman score: 1427; 66.5% identity (80.9% similar) in 361 aa overlap (1-352:1-344) 10 20 30 40 50 60 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL :::::::::::..::.:..:::.:::..::::::::::::::.: :::::::::::::.: NP_006 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 CGERVIVEHARGPRRD--G-SYGSGRSGYGY---RRSGRDKYGPPTRTEYRLIVENLSSR :::::::::::::::: : :::: .: :: : :::::::::.:::::::::::::: NP_006 CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE ::::::::.:::::::::::::: : ::::::: :::::::::.::::::.:::.:::.: NP_006 CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS ::: . .::::: :::.:::: ::: :::: .: .::::: : :::::.::: NP_006 DKPRTSHRRSYSGSRSRSRSRRRSR----SRSRRSS------RSRSRSISKSRSRSRSRS 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 RSQSRSRSKKEKSRSPSKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH ...:::::: .:::: ::.: .: : ..:::.:::. :. . .. .::::... NP_006 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEK------SRSRSRSRSPKEN 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 KS---KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK . ::::::::: : :..:: ... :::::.. :.:::::::.:. NP_006 GKGDIKSKSRSRSQSRSNSPLPVPP-SKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV : NP_006 D >>XP_005268056 (OMIM: 600914) PREDICTED: serine/arginine (271 aa) initn: 1188 init1: 480 opt: 1027 Z-score: 469.7 bits: 95.5 E(85289): 2e-19 Smith-Waterman score: 1027; 61.7% identity (81.6% similar) in 277 aa overlap (3-271:5-268) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: XP_005 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC .::.::: .::::. : :. : :: . .. :: :. . ::.::: :::::::::: XP_005 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED :::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: XP_005 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR ::.:.:: :::::..:: :::: ::::: :..:.:.::::::: :::.:.: :: XP_005 --GSKRHRSRSRSRSRTRSSSRSR----SRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS : .:..:... .:.:: : :..:::: .:::.: : XP_005 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 240 250 260 270 300 310 320 330 340 350 pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS >>XP_005268057 (OMIM: 600914) PREDICTED: serine/arginine (271 aa) initn: 1188 init1: 480 opt: 1027 Z-score: 469.7 bits: 95.5 E(85289): 2e-19 Smith-Waterman score: 1027; 61.7% identity (81.6% similar) in 277 aa overlap (3-271:5-268) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: XP_005 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC .::.::: .::::. : :. : :: . .. :: :. . ::.::: :::::::::: XP_005 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED :::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: XP_005 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR ::.:.:: :::::..:: :::: ::::: :..:.:.::::::: :::.:.: :: XP_005 --GSKRHRSRSRSRSRTRSSSRSR----SRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS : .:..:... .:.:: : :..:::: .:::.: : XP_005 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 240 250 260 270 300 310 320 330 340 350 pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS >>XP_016877082 (OMIM: 600914) PREDICTED: serine/arginine (271 aa) initn: 1188 init1: 480 opt: 1027 Z-score: 469.7 bits: 95.5 E(85289): 2e-19 Smith-Waterman score: 1027; 61.7% identity (81.6% similar) in 277 aa overlap (3-271:5-268) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: XP_016 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC .::.::: .::::. : :. : :: . .. :: :. . ::.::: :::::::::: XP_016 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED :::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: XP_016 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR ::.:.:: :::::..:: :::: ::::: :..:.:.::::::: :::.:.: :: XP_016 --GSKRHRSRSRSRSRTRSSSRSR----SRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS : .:..:... .:.:: : :..:::: .:::.: : XP_016 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 240 250 260 270 300 310 320 330 340 350 pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS >>NP_008856 (OMIM: 600914) serine/arginine-rich splicing (272 aa) initn: 1381 init1: 525 opt: 1020 Z-score: 466.7 bits: 95.0 E(85289): 2.9e-19 Smith-Waterman score: 1020; 61.0% identity (81.2% similar) in 277 aa overlap (3-271:5-269) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: NP_008 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC .::.::: .::::. : :. : :: . .. :: :. . ::.::: :::::::::: NP_008 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED :::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: NP_008 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR ::.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: :: NP_008 --GSKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS : .:..:... .:.:: : :..:::: .:::.: : NP_008 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 240 250 260 270 300 310 320 330 340 350 pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS >>NP_001307143 (OMIM: 600914) serine/arginine-rich splic (272 aa) initn: 1381 init1: 525 opt: 1020 Z-score: 466.7 bits: 95.0 E(85289): 2.9e-19 Smith-Waterman score: 1020; 61.0% identity (81.2% similar) in 277 aa overlap (3-271:5-269) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: NP_001 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC .::.::: .::::. : :. : :: . .. :: :. . ::.::: :::::::::: NP_001 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED :::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: NP_001 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR ::.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: :: NP_001 --GSKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS : .:..:... .:.:: : :..:::: .:::.: : NP_001 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 240 250 260 270 300 310 320 330 340 350 pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS >>NP_001034554 (OMIM: 600914) serine/arginine-rich splic (272 aa) initn: 1381 init1: 525 opt: 1020 Z-score: 466.7 bits: 95.0 E(85289): 2.9e-19 Smith-Waterman score: 1020; 61.0% identity (81.2% similar) in 277 aa overlap (3-271:5-269) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: NP_001 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC .::.::: .::::. : :. : :: . .. :: :. . ::.::: :::::::::: NP_001 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED :::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: NP_001 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR ::.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: :: NP_001 --GSKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS : .:..:... .:.:: : :..:::: .:::.: : NP_001 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 240 250 260 270 300 310 320 330 340 350 pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS >>XP_011535379 (OMIM: 600914) PREDICTED: serine/arginine (239 aa) initn: 676 init1: 525 opt: 646 Z-score: 308.5 bits: 65.5 E(85289): 1.9e-10 Smith-Waterman score: 896; 56.9% identity (74.8% similar) in 274 aa overlap (3-271:5-236) 10 20 30 40 50 pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK ::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.:: XP_011 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQ .::.:: .::.::: :::::::::: ::: XP_011 ELCSER-------------------------------NAPPVRTENRLIVENLSSRVSWQ 70 80 120 130 140 150 160 170 pF1KB5 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPG ::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: : XP_011 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE---G 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB5 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS-- :.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: ::: XP_011 SKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSRSPV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 --QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR .:..:... .:.:: : :..:::: .:::.: : XP_011 PEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN 210 220 230 300 310 320 330 340 350 pF1KB5 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 494 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:25:46 2016 done: Sat Nov 5 15:25:48 2016 Total Scan time: 10.730 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]