FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5880, 496 aa 1>>>pF1KB5880 496 - 496 aa - 496 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5861+/-0.000844; mu= 12.6223+/- 0.051 mean_var=106.1530+/-20.743, 0's: 0 Z-trim(109.9): 13 B-trim: 0 in 0/51 Lambda= 0.124482 statistics sampled from 11203 (11207) to 11203 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.344), width: 16 Scan time: 2.980 The best scores are: opt bits E(32554) CCDS11494.1 NMT1 gene_id:4836|Hs108|chr17 ( 496) 3374 616.6 1.9e-176 CCDS7109.1 NMT2 gene_id:9397|Hs108|chr10 ( 498) 2454 451.4 1.1e-126 CCDS76284.1 NMT2 gene_id:9397|Hs108|chr10 ( 485) 2373 436.8 2.5e-122 >>CCDS11494.1 NMT1 gene_id:4836|Hs108|chr17 (496 aa) initn: 3374 init1: 3374 opt: 3374 Z-score: 3281.1 bits: 616.6 E(32554): 1.9e-176 Smith-Waterman score: 3374; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN 430 440 450 460 470 480 490 pF1KB5 WKCPSMGAEKVGLVLQ :::::::::::::::: CCDS11 WKCPSMGAEKVGLVLQ 490 >>CCDS7109.1 NMT2 gene_id:9397|Hs108|chr10 (498 aa) initn: 2573 init1: 2387 opt: 2454 Z-score: 2388.2 bits: 451.4 E(32554): 1.1e-126 Smith-Waterman score: 2519; 73.2% identity (88.6% similar) in 508 aa overlap (1-496:1-498) 10 20 30 40 50 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCS-DCENEEDNSYNRGGLSPANDTGAKKKKK ::..::.:.. . : . .. :. : .:::.. . .: ::.. ::::::: CCDS71 MAEDSESAASQQSLEL--------DDQDTCGIDGDNEEETEHAKG--SPGGYLGAKKKKK 10 20 30 40 50 60 70 80 90 100 pF1KB5 KQKKKKEK----GSETDSAQD-------QPVKMNSLPAERIQEIQKAIELFSVGQGPAKT :::.:::: :...:::.: :: : :.: ...:.::.:.::.:. ::::.. CCDS71 KQKRKKEKPNSGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARN 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 MEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGV ..::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::.: : CCDS71 IDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISA ::::::::::::::::::::::::::::::::::::::: :::::::: :..:::::::: CCDS71 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 IPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLP :::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS71 IPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 KPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPV ::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: ::: CCDS71 KPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 VHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIM :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..::::::::::::.: CCDS71 VRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 NHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG .::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::::::: CCDS71 HHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFG 420 430 440 450 460 470 470 480 490 pF1KB5 IGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::.::. .:::::::: CCDS71 IGDGNLQYYLYNWRCPGTDSEKVGLVLQ 480 490 >>CCDS76284.1 NMT2 gene_id:9397|Hs108|chr10 (485 aa) initn: 2370 init1: 2370 opt: 2373 Z-score: 2309.7 bits: 436.8 E(32554): 2.5e-122 Smith-Waterman score: 2373; 80.1% identity (94.1% similar) in 422 aa overlap (75-496:65-485) 50 60 70 80 90 100 pF1KB5 GLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQG ..:: . :.: ...:.::.:.::.:. :: CCDS76 EAPSQTRHLIPRRLKFSSLRNTTPSGSRFQREQPWN-PSVPMQKLQDIQRAMELLSACQG 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB5 PAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLG ::....::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::. CCDS76 PARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLS 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB5 DRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVG : :::::::::::::::::::::::::::::::::::::::: :::::::: :..:::: CCDS76 DAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVG 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB5 FISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAG :::::::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::: CCDS76 FISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAG 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB5 VVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETK ::::::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: : CCDS76 VVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPK 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB5 DIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLP :: :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..:::::::::: CCDS76 DIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLP 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB5 STIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEK ::.:.::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::: CCDS76 STVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEK 400 410 420 430 440 450 470 480 490 pF1KB5 LKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::::::.::. .:::::::: CCDS76 LKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ 460 470 480 496 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:35:43 2016 done: Sat Nov 5 10:35:43 2016 Total Scan time: 2.980 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]