FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5880, 496 aa 1>>>pF1KB5880 496 - 496 aa - 496 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7439+/-0.000352; mu= 11.5701+/- 0.022 mean_var=110.2375+/-21.702, 0's: 0 Z-trim(117.4): 13 B-trim: 343 in 1/53 Lambda= 0.122155 statistics sampled from 29300 (29313) to 29300 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.344), width: 16 Scan time: 7.310 The best scores are: opt bits E(85289) NP_066565 (OMIM: 160993) glycylpeptide N-tetradeca ( 496) 3374 605.5 1.1e-172 XP_011523160 (OMIM: 160993) PREDICTED: glycylpepti ( 515) 3018 542.7 9e-154 NP_004799 (OMIM: 603801) glycylpeptide N-tetradeca ( 498) 2454 443.3 7.3e-124 XP_005252699 (OMIM: 603801) PREDICTED: glycylpepti ( 495) 2419 437.2 5.2e-122 XP_016872436 (OMIM: 603801) PREDICTED: glycylpepti ( 502) 2419 437.2 5.3e-122 NP_001295224 (OMIM: 603801) glycylpeptide N-tetrad ( 485) 2373 429.1 1.4e-119 XP_016872442 (OMIM: 603801) PREDICTED: glycylpepti ( 411) 2355 425.8 1.1e-118 XP_016872438 (OMIM: 603801) PREDICTED: glycylpepti ( 482) 2338 422.9 1e-117 XP_016872437 (OMIM: 603801) PREDICTED: glycylpepti ( 489) 2338 422.9 1e-117 XP_016872441 (OMIM: 603801) PREDICTED: glycylpepti ( 415) 2320 419.7 8.1e-117 XP_016872440 (OMIM: 603801) PREDICTED: glycylpepti ( 428) 1150 213.5 9.8e-55 XP_006717602 (OMIM: 603801) PREDICTED: glycylpepti ( 441) 1150 213.5 1e-54 XP_016872439 (OMIM: 603801) PREDICTED: glycylpepti ( 445) 1115 207.3 7.2e-53 >>NP_066565 (OMIM: 160993) glycylpeptide N-tetradecanoyl (496 aa) initn: 3374 init1: 3374 opt: 3374 Z-score: 3221.0 bits: 605.5 E(85289): 1.1e-172 Smith-Waterman score: 3374; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN 430 440 450 460 470 480 490 pF1KB5 WKCPSMGAEKVGLVLQ :::::::::::::::: NP_066 WKCPSMGAEKVGLVLQ 490 >>XP_011523160 (OMIM: 160993) PREDICTED: glycylpeptide N (515 aa) initn: 3018 init1: 3018 opt: 3018 Z-score: 2881.6 bits: 542.7 E(85289): 9e-154 Smith-Waterman score: 3018; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN :::::::::::::::::::::::: XP_011 SFYNVHTQTPLLDLMSDALVLAKMVRSRRGGLWRCAGKRQWSHGEHSSRDAASHGLEALS 430 440 450 460 470 480 >>NP_004799 (OMIM: 603801) glycylpeptide N-tetradecanoyl (498 aa) initn: 2573 init1: 2387 opt: 2454 Z-score: 2344.7 bits: 443.3 E(85289): 7.3e-124 Smith-Waterman score: 2519; 73.2% identity (88.6% similar) in 508 aa overlap (1-496:1-498) 10 20 30 40 50 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCS-DCENEEDNSYNRGGLSPANDTGAKKKKK ::..::.:.. . : . .. :. : .:::.. . .: ::.. ::::::: NP_004 MAEDSESAASQQSLEL--------DDQDTCGIDGDNEEETEHAKG--SPGGYLGAKKKKK 10 20 30 40 50 60 70 80 90 100 pF1KB5 KQKKKKEK----GSETDSAQD-------QPVKMNSLPAERIQEIQKAIELFSVGQGPAKT :::.:::: :...:::.: :: : :.: ...:.::.:.::.:. ::::.. NP_004 KQKRKKEKPNSGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARN 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 MEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGV ..::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::.: : NP_004 IDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISA ::::::::::::::::::::::::::::::::::::::: :::::::: :..:::::::: NP_004 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 IPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLP :::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::::::: NP_004 IPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 KPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPV ::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: ::: NP_004 KPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 VHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIM :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..::::::::::::.: NP_004 VRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 NHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG .::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::::::: NP_004 HHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFG 420 430 440 450 460 470 470 480 490 pF1KB5 IGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::.::. .:::::::: NP_004 IGDGNLQYYLYNWRCPGTDSEKVGLVLQ 480 490 >>XP_005252699 (OMIM: 603801) PREDICTED: glycylpeptide N (495 aa) initn: 2538 init1: 2352 opt: 2419 Z-score: 2311.4 bits: 437.2 E(85289): 5.2e-122 Smith-Waterman score: 2484; 72.9% identity (88.4% similar) in 502 aa overlap (1-490:1-492) 10 20 30 40 50 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCS-DCENEEDNSYNRGGLSPANDTGAKKKKK ::..::.:.. . : . .. :. : .:::.. . .: ::.. ::::::: XP_005 MAEDSESAASQQSLEL--------DDQDTCGIDGDNEEETEHAKG--SPGGYLGAKKKKK 10 20 30 40 50 60 70 80 90 100 pF1KB5 KQKKKKEK----GSETDSAQD-------QPVKMNSLPAERIQEIQKAIELFSVGQGPAKT :::.:::: :...:::.: :: : :.: ...:.::.:.::.:. ::::.. XP_005 KQKRKKEKPNSGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARN 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 MEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGV ..::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::.: : XP_005 IDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISA ::::::::::::::::::::::::::::::::::::::: :::::::: :..:::::::: XP_005 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 IPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLP :::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::::::: XP_005 IPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 KPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPV ::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: ::: XP_005 KPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 VHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIM :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..::::::::::::.: XP_005 VRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 NHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG .::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::::::: XP_005 HHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFG 420 430 440 450 460 470 470 480 490 pF1KB5 IGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::.::. .:: XP_005 IGDGNLQYYLYNWRCPGTDSEKKVC 480 490 >>XP_016872436 (OMIM: 603801) PREDICTED: glycylpeptide N (502 aa) initn: 2538 init1: 2352 opt: 2419 Z-score: 2311.3 bits: 437.2 E(85289): 5.3e-122 Smith-Waterman score: 2484; 72.9% identity (88.4% similar) in 502 aa overlap (1-490:1-492) 10 20 30 40 50 pF1KB5 MADESETAVKPPAPPLPQMMEGNGNGHEHCS-DCENEEDNSYNRGGLSPANDTGAKKKKK ::..::.:.. . : . .. :. : .:::.. . .: ::.. ::::::: XP_016 MAEDSESAASQQSLEL--------DDQDTCGIDGDNEEETEHAKG--SPGGYLGAKKKKK 10 20 30 40 50 60 70 80 90 100 pF1KB5 KQKKKKEK----GSETDSAQD-------QPVKMNSLPAERIQEIQKAIELFSVGQGPAKT :::.:::: :...:::.: :: : :.: ...:.::.:.::.:. ::::.. XP_016 KQKRKKEKPNSGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARN 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB5 MEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGV ..::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::.: : XP_016 IDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB5 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISA ::::::::::::::::::::::::::::::::::::::: :::::::: :..:::::::: XP_016 LKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 IPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLP :::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 IPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 KPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPV ::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: ::: XP_016 KPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKS 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 VHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIM :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..::::::::::::.: XP_016 VRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVM 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 NHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG .::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::::::: XP_016 HHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFG 420 430 440 450 460 470 470 480 490 pF1KB5 IGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::.::. .:: XP_016 IGDGNLQYYLYNWRCPGTDSEKALYQPLKKSI 480 490 500 >>NP_001295224 (OMIM: 603801) glycylpeptide N-tetradecan (485 aa) initn: 2370 init1: 2370 opt: 2373 Z-score: 2267.7 bits: 429.1 E(85289): 1.4e-119 Smith-Waterman score: 2373; 80.1% identity (94.1% similar) in 422 aa overlap (75-496:65-485) 50 60 70 80 90 100 pF1KB5 GLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQG ..:: . :.: ...:.::.:.::.:. :: NP_001 EAPSQTRHLIPRRLKFSSLRNTTPSGSRFQREQPWN-PSVPMQKLQDIQRAMELLSACQG 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB5 PAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLG ::....::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::. NP_001 PARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLS 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB5 DRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVG : :::::::::::::::::::::::::::::::::::::::: :::::::: :..:::: NP_001 DAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVG 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB5 FISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAG :::::::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::: NP_001 FISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAG 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB5 VVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETK ::::::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: : NP_001 VVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPK 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB5 DIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLP :: :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..:::::::::: NP_001 DIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLP 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB5 STIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEK ::.:.::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::: NP_001 STVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEK 400 410 420 430 440 450 470 480 490 pF1KB5 LKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::::::.::. .:::::::: NP_001 LKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ 460 470 480 >>XP_016872442 (OMIM: 603801) PREDICTED: glycylpeptide N (411 aa) initn: 2355 init1: 2355 opt: 2355 Z-score: 2251.6 bits: 425.8 E(85289): 1.1e-118 Smith-Waterman score: 2355; 81.5% identity (94.9% similar) in 410 aa overlap (87-496:2-411) 60 70 80 90 100 110 pF1KB5 KKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRS ...:.::.:.::.:. ::::....::.:. XP_016 MQKLQDIQRAMELLSACQGPARNIDEAAKHR 10 20 30 120 130 140 150 160 170 pF1KB5 YQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLL :::::::::::: ::...:: .::::::.:::::.::::: ::.:::.: ::::::::: XP_016 YQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLL 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 NENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIY ::::::::::::::::::::::::::::::: :::::::: :..:::::::::::::.:: XP_016 NENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIY 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 DTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRY :. ::::::::::::::::::::::::::::::::.::::::::::::::::::..:::: XP_016 DSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRY 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 WHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRY ::::::::::.::::::::::::.::::::::::.. ::.:::::: ::: :..:.. : XP_016 WHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTY 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 LKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSL ::::::.:::..::: ::: :.:.::::::::. ::..::::::::::::.:.::.:::: XP_016 LKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSL 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 KAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQY ::::::::.::.:::::::::::.::: :::::::::::::::::::::::::::::::: XP_016 KAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQY 340 350 360 370 380 390 480 490 pF1KB5 YLYNWKCPSMGAEKVGLVLQ :::::.::. .:::::::: XP_016 YLYNWRCPGTDSEKVGLVLQ 400 410 >>XP_016872438 (OMIM: 603801) PREDICTED: glycylpeptide N (482 aa) initn: 2335 init1: 2335 opt: 2338 Z-score: 2234.4 bits: 422.9 E(85289): 1e-117 Smith-Waterman score: 2338; 79.8% identity (94.0% similar) in 416 aa overlap (75-490:65-479) 50 60 70 80 90 100 pF1KB5 GLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQG ..:: . :.: ...:.::.:.::.:. :: XP_016 EAPSQTRHLIPRRLKFSSLRNTTPSGSRFQREQPWN-PSVPMQKLQDIQRAMELLSACQG 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB5 PAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLG ::....::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::. XP_016 PARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLS 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB5 DRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVG : :::::::::::::::::::::::::::::::::::::::: :::::::: :..:::: XP_016 DAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVG 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB5 FISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAG :::::::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::: XP_016 FISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAG 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB5 VVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETK ::::::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: : XP_016 VVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPK 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB5 DIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLP :: :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..:::::::::: XP_016 DIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLP 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB5 STIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEK ::.:.::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::: XP_016 STVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEK 400 410 420 430 440 450 470 480 490 pF1KB5 LKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::::::.::. .:: XP_016 LKFGIGDGNLQYYLYNWRCPGTDSEKKVC 460 470 480 >>XP_016872437 (OMIM: 603801) PREDICTED: glycylpeptide N (489 aa) initn: 2335 init1: 2335 opt: 2338 Z-score: 2234.3 bits: 422.9 E(85289): 1e-117 Smith-Waterman score: 2338; 79.8% identity (94.0% similar) in 416 aa overlap (75-490:65-479) 50 60 70 80 90 100 pF1KB5 GLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQG ..:: . :.: ...:.::.:.::.:. :: XP_016 EAPSQTRHLIPRRLKFSSLRNTTPSGSRFQREQPWN-PSVPMQKLQDIQRAMELLSACQG 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB5 PAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLG ::....::.:. :::::::::::: ::...:: .::::::.:::::.::::: ::.:::. XP_016 PARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLS 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB5 DRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVG : :::::::::::::::::::::::::::::::::::::::: :::::::: :..:::: XP_016 DAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVG 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB5 FISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAG :::::::::.:::. ::::::::::::::::::::::::::::::::.:::::::::::: XP_016 FISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAG 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB5 VVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETK ::::::..::::::::::::::.::::::::::::.::::::::::.. ::.:::::: : XP_016 VVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPK 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB5 DIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLP :: :..:.. :::::::.:::..::: ::: :.:.::::::::. ::..:::::::::: XP_016 DIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLP 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB5 STIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEK ::.:.::.::::::::::::.::.:::::::::::.::: :::::::::::::::::::: XP_016 STVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEK 400 410 420 430 440 450 470 480 490 pF1KB5 LKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ :::::::::::::::::.::. .:: XP_016 LKFGIGDGNLQYYLYNWRCPGTDSEKALYQPLKKSI 460 470 480 >>XP_016872441 (OMIM: 603801) PREDICTED: glycylpeptide N (415 aa) initn: 2320 init1: 2320 opt: 2320 Z-score: 2218.2 bits: 419.7 E(85289): 8.1e-117 Smith-Waterman score: 2320; 81.2% identity (94.8% similar) in 404 aa overlap (87-490:2-405) 60 70 80 90 100 110 pF1KB5 KKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRS ...:.::.:.::.:. ::::....::.:. XP_016 MQKLQDIQRAMELLSACQGPARNIDEAAKHR 10 20 30 120 130 140 150 160 170 pF1KB5 YQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLL :::::::::::: ::...:: .::::::.:::::.::::: ::.:::.: ::::::::: XP_016 YQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLL 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 NENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIY ::::::::::::::::::::::::::::::: :::::::: :..:::::::::::::.:: XP_016 NENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIY 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 DTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRY :. ::::::::::::::::::::::::::::::::.::::::::::::::::::..:::: XP_016 DSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRY 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 WHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRY ::::::::::.::::::::::::.::::::::::.. ::.:::::: ::: :..:.. : XP_016 WHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTY 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 LKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSL ::::::.:::..::: ::: :.:.::::::::. ::..::::::::::::.:.::.:::: XP_016 LKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSL 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 KAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQY ::::::::.::.:::::::::::.::: :::::::::::::::::::::::::::::::: XP_016 KAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQY 340 350 360 370 380 390 480 490 pF1KB5 YLYNWKCPSMGAEKVGLVLQ :::::.::. .:: XP_016 YLYNWRCPGTDSEKALYQPLKKSI 400 410 496 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:35:44 2016 done: Sat Nov 5 10:35:45 2016 Total Scan time: 7.310 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]