FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5891, 498 aa
1>>>pF1KB5891 498 - 498 aa - 498 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.3205+/-0.00127; mu= -28.6639+/- 0.077
mean_var=857.7629+/-175.585, 0's: 0 Z-trim(117.8): 125 B-trim: 0 in 0/55
Lambda= 0.043792
statistics sampled from 18490 (18598) to 18490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.571), width: 16
Scan time: 4.320
The best scores are: opt bits E(32554)
CCDS304.1 WASF2 gene_id:10163|Hs108|chr1 ( 498) 3525 237.7 2.3e-62
CCDS55582.1 WASF2 gene_id:10163|Hs108|chr1 ( 281) 1841 131.0 1.6e-30
CCDS76626.1 WASF3 gene_id:10810|Hs108|chr13 ( 499) 1690 121.7 1.8e-27
CCDS9318.1 WASF3 gene_id:10810|Hs108|chr13 ( 502) 1590 115.4 1.5e-25
CCDS5080.1 WASF1 gene_id:8936|Hs108|chr6 ( 559) 1240 93.4 7.2e-19
>>CCDS304.1 WASF2 gene_id:10163|Hs108|chr1 (498 aa)
initn: 3525 init1: 3525 opt: 3525 Z-score: 1233.1 bits: 237.7 E(32554): 2.3e-62
Smith-Waterman score: 3525; 100.0% identity (100.0% similar) in 498 aa overlap (1-498:1-498)
10 20 30 40 50 60
pF1KB5 MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVATILSRRIAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 SDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVATILSRRIAVE
430 440 450 460 470 480
490
pF1KB5 YSDSEDDSSEFDEDDWSD
::::::::::::::::::
CCDS30 YSDSEDDSSEFDEDDWSD
490
>>CCDS55582.1 WASF2 gene_id:10163|Hs108|chr1 (281 aa)
initn: 1841 init1: 1841 opt: 1841 Z-score: 661.3 bits: 131.0 E(32554): 1.6e-30
Smith-Waterman score: 1841; 99.3% identity (99.6% similar) in 276 aa overlap (1-276:1-276)
10 20 30 40 50 60
pF1KB5 MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP
:::::::::::::::::::::::::::::::::: .
CCDS55 VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFRFSAAQG
250 260 270 280
310 320 330 340 350 360
pF1KB5 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD
>>CCDS76626.1 WASF3 gene_id:10810|Hs108|chr13 (499 aa)
initn: 1190 init1: 1190 opt: 1690 Z-score: 606.6 bits: 121.7 E(32554): 1.8e-27
Smith-Waterman score: 1690; 53.5% identity (71.5% similar) in 512 aa overlap (1-498:1-499)
10 20 30 40 50
pF1KB5 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN
:::: :::::::::: .:: .. :::::::: ::: .::::.::::.:::::::::..::
CCDS76 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP
.: :..:: .:.::: ::::::: :::::: :: .:::.:::.:::.. ..::.: :
CCDS76 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR
: . :: : ::::: ::::::: :..::::::::::::::::::::::.: ::::...
CCDS76 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 KEK-KDNPNRGN-VNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGC
.:: : ::::.. :: ::..:::::::. ::: ::. . .:: .: .::
CCDS76 REKHKLNPNRNQQVNVRKVRTRKEEWERRKMGIEFMSDAKKLEQAGSAKEDRVPSGS--H
190 200 210 220 230
240 250 260 270 280 290
pF1KB5 VENVDASSYPPPPQSDSASSP-SPSFSEDNLPPP-PAEFSYPVDNQRGSGLAGPKRSSVV
. .: ::: :. . .: .::.. ..:: :: : .... :. .. ..
CCDS76 ASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA--SQAAEHEYRPPSASARHMALN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSF
:..::: :: .: : . : : : :. : .. : :::: :: .
CCDS76 RPQQPPPPPPPQAPEGSQ-------ASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVI
300 310 320 330 340
360 370 380 390 400
pF1KB5 PP-HPDFAAP---PPPPPPPAADYPTLPPPPLSQPTG---GAPPPP-PPPPPPGPPPPPF
: . :..: : :: ::. : :: :: ::::: ::::::::: :
CCDS76 PSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPG-
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB5 TGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDVVG
.. ...: ::.... . . . : .::::::::.:::.:.::..:.:::::: ::. ::
CCDS76 SSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVG
410 420 430 440 450 460
470 480 490
pF1KB5 NDVATILSRRIAVEYSDSEDDSSEFDEDDWSD
::::::::::::::::::.::: ::::.::::
CCDS76 NDVATILSRRIAVEYSDSDDDS-EFDENDWSD
470 480 490
>>CCDS9318.1 WASF3 gene_id:10810|Hs108|chr13 (502 aa)
initn: 869 init1: 869 opt: 1590 Z-score: 572.4 bits: 115.4 E(32554): 1.5e-25
Smith-Waterman score: 1590; 50.6% identity (70.7% similar) in 516 aa overlap (1-498:1-502)
10 20 30 40 50
pF1KB5 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN
:::: :::::::::: .:: .. :::::::: ::: .::::.::::.:::::::::..::
CCDS93 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP
.: :..:: .:.::: ::::::: :::::: :: .:::.:::.:::.. ..::.: :
CCDS93 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR
: . :: : ::::: ::::::: :..::::::::::::::::::::::.: ::::...
CCDS93 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 KEKK-DNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIG--
..:. :. .: . :: ..:..::. : . .:. . ..:. : : . ..::..
CCDS93 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKEL-RPDNRLSQSVYHGA--SSEGSLSPD
190 200 210 220 230
240 250 260 270 280 290
pF1KB5 ---CVENVDASSYPPPPQSDSASSP-SPSFSEDNLPPP-PAEFSYPVDNQRGSGLAGPKR
. .: ::: :. . .: .::.. ..:: :: : .... :. ..
CCDS93 TRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA--SQAAEHEYRPPSASARH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS
.. :..::: :: .: : . : : : :. : .. : ::::
CCDS93 MALNRPQQPPPPPPPQAPEGSQ-------ASAPMAPADYGMLPAQIIEYYNPSGPPPPPP
300 310 320 330 340
360 370 380 390 400
pF1KB5 PPSFPP-HPDFAAP---PPPPPPPAADYPTLPPPPLSQPTG---GAPPPP-PPPPPPGPP
:: .: . :..: : :: ::. : :: :: ::::: :::::::::
CCDS93 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB5 PPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KR
: .. ...: ::.... . . . : .::::::::.:::.:.::..:.:::::: ::
CCDS93 GPG-SSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKR
410 420 430 440 450 460
470 480 490
pF1KB5 DVVGNDVATILSRRIAVEYSDSEDDSSEFDEDDWSD
. ::::::::::::::::::::.::: ::::.::::
CCDS93 EPVGNDVATILSRRIAVEYSDSDDDS-EFDENDWSD
470 480 490 500
>>CCDS5080.1 WASF1 gene_id:8936|Hs108|chr6 (559 aa)
initn: 1140 init1: 954 opt: 1240 Z-score: 452.3 bits: 93.4 E(32554): 7.2e-19
Smith-Waterman score: 1490; 48.6% identity (65.9% similar) in 545 aa overlap (1-469:1-531)
10 20 30 40 50
pF1KB5 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN
:::: :::.:::::. .:: ....::::::::.:::.::::.::::::::::::::..:.
CCDS50 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP
.:. ::.:: ::::::.:.::::::::::.::: :. ::::::::::::.::::..::.:
CCDS50 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR
. :::..:. ::::: ::::::::::.:::::.::::::::::::::::.: :::::..
CCDS50 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK
130 140 150 160 170 180
180 190 200 210 220
pF1KB5 KEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL---------GTSGY----PP
... : :.. . :: . :..::.:. .: :..:. .: : ... :
CCDS50 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ
190 200 210 220 230 240
230 240 250 260 270
pF1KB5 TLV-YQNGSIGCV---------------ENVDASSYPPPPQSDSASSPSPSFSEDNLPPP
: : ...:: . : : . . ::: : : . . :
CCDS50 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP-------PPPMHGAGDAKPI
250 260 270 280 290
280 290 300 310 320
pF1KB5 PAEFSYP---VDNQRGSGLAGPKRSSV-VSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP
:. .: ..:. : .: :. : :::. ::: ::: : . . : . ::::
CCDS50 PTCISSATGLIENRPQSPATG--RTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPP
300 310 320 330 340 350
330 340 350 360 370
pF1KB5 -PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP--PP-----PPPAADYP--
:: ::::: ... .:..::::.: .. : :::: :: :: : :
CCDS50 VPP----PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC
360 370 380 390 400
380 390 400 410
pF1KB5 -TLPPPPLSQ-PTGGAPPPPPPPP--PPG--------------PP----PPPFTGADGQ-
:.: :: : . : :::::::: ::: :: : : : : :
CCDS50 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPST-APGPH
410 420 430 440 450 460
420 430 440 450 460
pF1KB5 -PAIPP-------PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDV
: .:: : :. . :.::..::::: :: :::.:.:::.:::::::: :..
CCDS50 VPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHER
470 480 490 500 510 520
470 480 490
pF1KB5 VGNDVATILSRRIAVEYSDSEDDSSEFDEDDWSD
. :::
CCDS50 IENDVATILSRRIAVEYSDSEDDSEFDEVDWLE
530 540 550
498 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:28:39 2016 done: Sat Nov 5 15:28:40 2016
Total Scan time: 4.320 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]