FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5893, 499 aa 1>>>pF1KB5893 499 - 499 aa - 499 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7641+/-0.000406; mu= 16.0973+/- 0.025 mean_var=89.6500+/-18.028, 0's: 0 Z-trim(113.0): 144 B-trim: 177 in 1/57 Lambda= 0.135456 statistics sampled from 21933 (22117) to 21933 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.259), width: 16 Scan time: 8.760 The best scores are: opt bits E(85289) NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 3362 667.6 2.3e-191 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 3231 642.0 1.3e-183 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 1848 371.7 2.6e-102 NP_001009552 (OMIM: 176916) serine/threonine-prote ( 309) 799 166.6 9.6e-41 NP_002706 (OMIM: 176915) serine/threonine-protein ( 309) 783 163.4 8.4e-40 NP_001290432 (OMIM: 602035) serine/threonine-prote ( 307) 758 158.5 2.5e-38 NP_002711 (OMIM: 602035) serine/threonine-protein ( 307) 758 158.5 2.5e-38 NP_002712 (OMIM: 612725) serine/threonine-protein ( 305) 708 148.8 2.1e-35 NP_002701 (OMIM: 176914) serine/threonine-protein ( 323) 707 148.6 2.6e-35 NP_002699 (OMIM: 176875) serine/threonine-protein ( 330) 707 148.6 2.6e-35 NP_001008709 (OMIM: 176875) serine/threonine-prote ( 341) 707 148.6 2.7e-35 XP_011536807 (OMIM: 176914) PREDICTED: serine/thre ( 330) 705 148.2 3.4e-35 NP_001231903 (OMIM: 176914) serine/threonine-prote ( 337) 705 148.2 3.5e-35 XP_011536806 (OMIM: 176914) PREDICTED: serine/thre ( 362) 705 148.2 3.7e-35 NP_002700 (OMIM: 600590) serine/threonine-protein ( 327) 703 147.8 4.4e-35 NP_996759 (OMIM: 600590) serine/threonine-protein ( 327) 703 147.8 4.4e-35 XP_011517149 (OMIM: 612725) PREDICTED: serine/thre ( 293) 701 147.4 5.4e-35 NP_001116827 (OMIM: 612725) serine/threonine-prote ( 342) 701 147.4 6e-35 NP_996756 (OMIM: 176875) serine/threonine-protein ( 286) 686 144.4 4e-34 XP_016871868 (OMIM: 114106) PREDICTED: serine/thre ( 426) 639 135.4 3.2e-31 XP_005270001 (OMIM: 114106) PREDICTED: serine/thre ( 514) 639 135.4 3.7e-31 NP_001135826 (OMIM: 114106) serine/threonine-prote ( 515) 639 135.4 3.7e-31 NP_066955 (OMIM: 114106) serine/threonine-protein ( 524) 639 135.5 3.7e-31 NP_001135825 (OMIM: 114106) serine/threonine-prote ( 525) 639 135.5 3.7e-31 NP_001124164 (OMIM: 114105) serine/threonine-prote ( 469) 634 134.4 6.8e-31 XP_016863854 (OMIM: 114105) PREDICTED: serine/thre ( 509) 634 134.5 7.2e-31 NP_001124163 (OMIM: 114105) serine/threonine-prote ( 511) 634 134.5 7.2e-31 NP_000935 (OMIM: 114105) serine/threonine-protein ( 521) 634 134.5 7.3e-31 XP_016869100 (OMIM: 114107) PREDICTED: serine/thre ( 418) 629 133.4 1.2e-30 NP_001230904 (OMIM: 114107) serine/threonine-prote ( 502) 629 133.5 1.4e-30 NP_005596 (OMIM: 114107) serine/threonine-protein ( 512) 629 133.5 1.4e-30 NP_001230903 (OMIM: 114107) serine/threonine-prote ( 521) 629 133.5 1.4e-30 NP_001276898 (OMIM: 114106) serine/threonine-prote ( 410) 626 132.8 1.8e-30 XP_016878893 (OMIM: 602035) PREDICTED: serine/thre ( 228) 615 130.5 5e-30 XP_016878892 (OMIM: 602035) PREDICTED: serine/thre ( 228) 615 130.5 5e-30 NP_001290435 (OMIM: 602035) serine/threonine-prote ( 228) 615 130.5 5e-30 NP_001290436 (OMIM: 602035) serine/threonine-prote ( 228) 615 130.5 5e-30 XP_016869099 (OMIM: 114107) PREDICTED: serine/thre ( 439) 602 128.2 4.9e-29 NP_001116841 (OMIM: 612725) serine/threonine-prote ( 283) 575 122.8 1.3e-27 NP_006230 (OMIM: 602256) serine/threonine-protein ( 753) 563 120.7 1.5e-26 XP_011530341 (OMIM: 602256) PREDICTED: serine/thre ( 753) 563 120.7 1.5e-26 NP_689412 (OMIM: 300109) serine/threonine-protein ( 591) 549 117.9 8.1e-26 NP_689410 (OMIM: 300109) serine/threonine-protein ( 625) 549 117.9 8.5e-26 NP_006231 (OMIM: 300109) serine/threonine-protein ( 653) 549 117.9 8.8e-26 XP_005274610 (OMIM: 300109) PREDICTED: serine/thre ( 653) 549 117.9 8.8e-26 XP_006721124 (OMIM: 602035) PREDICTED: serine/thre ( 273) 540 115.9 1.5e-25 NP_001290433 (OMIM: 602035) serine/threonine-prote ( 273) 540 115.9 1.5e-25 XP_016885101 (OMIM: 300109) PREDICTED: serine/thre ( 563) 544 116.9 1.5e-25 NP_001276897 (OMIM: 114106) serine/threonine-prote ( 514) 428 94.2 9.5e-19 NP_003306 (OMIM: 601964) dnaJ homolog subfamily C ( 494) 289 67.0 1.4e-10 >>NP_006238 (OMIM: 600658) serine/threonine-protein phos (499 aa) initn: 3362 init1: 3362 opt: 3362 Z-score: 3556.5 bits: 667.6 E(85289): 2.3e-191 Smith-Waterman score: 3362; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499) 10 20 30 40 50 60 pF1KB5 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 430 440 450 460 470 480 490 pF1KB5 HPNVKPMAYANTLLQLGMM ::::::::::::::::::: NP_006 HPNVKPMAYANTLLQLGMM 490 >>XP_016882424 (OMIM: 600658) PREDICTED: serine/threonin (551 aa) initn: 3223 init1: 3223 opt: 3231 Z-score: 3417.5 bits: 642.0 E(85289): 1.3e-183 Smith-Waterman score: 3231; 99.4% identity (99.6% similar) in 484 aa overlap (1-483:1-484) 10 20 30 40 50 60 pF1KB5 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAV- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVV 430 440 450 460 470 480 480 490 pF1KB5 PHPNVKPMAYANTLLQLGMM ::. XP_016 SHPSGPLPLPSRPGDKEAETLVRGRGRFCRWVLRGSVLTSVHPTCPGPTASSQRQAHGLC 490 500 510 520 530 540 >>NP_001191213 (OMIM: 600658) serine/threonine-protein p (477 aa) initn: 1848 init1: 1848 opt: 1848 Z-score: 1957.7 bits: 371.7 E(85289): 2.6e-102 Smith-Waterman score: 3190; 95.6% identity (95.6% similar) in 499 aa overlap (1-499:1-477) 10 20 30 40 50 60 pF1KB5 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC ::::::::::::::::::::::::::::::: ::::::: NP_001 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQ----------------------TEKITVC 190 200 210 250 260 270 280 290 300 pF1KB5 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 400 410 420 430 440 450 490 pF1KB5 HPNVKPMAYANTLLQLGMM ::::::::::::::::::: NP_001 HPNVKPMAYANTLLQLGMM 460 470 >>NP_001009552 (OMIM: 176916) serine/threonine-protein p (309 aa) initn: 646 init1: 481 opt: 799 Z-score: 852.5 bits: 166.6 E(85289): 9.6e-41 Smith-Waterman score: 799; 41.2% identity (72.6% similar) in 296 aa overlap (189-480:5-293) 160 170 180 190 200 210 pF1KB5 RSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYK---DQKKLHRKCAYQILVQ .: ::: :: . . :.:... . . . NP_001 MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEK 10 20 30 220 230 240 250 260 270 pF1KB5 VKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDR .::.:.: :.. :. .:::::.::::.::...:...: .:: :.: ::.::: NP_001 AKEILTKESNVQEVRCP----VTVCGDVHGQFHDLMELFRIGGKSPDTN-YLFMGDYVDR 40 50 60 70 80 280 290 300 310 320 330 pF1KB5 GSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEV : .:::.. : ..:. ::... .::::::. ...:.::: : :: .:.... :... NP_001 GYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL 90 100 110 120 130 140 340 350 360 370 380 390 pF1KB5 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG :..:::. ..:... .:::: : . ::: :: ..: .. : :::::::::::. ..: NP_001 FDYLPLTALVDGQIFCLHGGL-SPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGG 150 160 170 180 190 200 400 410 420 430 440 450 pF1KB5 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ .:: ::.. :: :....: . :.: . :.:.. :::. : ::.::::::: . NP_001 WGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYR 210 220 230 240 250 260 460 470 480 490 pF1KB5 MGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM ::.:. ..:. . :. .: :: .: NP_001 CGNQAAIMELDDT-LKYSFLQFDPAPRRGEPHVTRRTPDYFL 270 280 290 300 >>NP_002706 (OMIM: 176915) serine/threonine-protein phos (309 aa) initn: 634 init1: 468 opt: 783 Z-score: 835.6 bits: 163.4 E(85289): 8.4e-40 Smith-Waterman score: 783; 41.0% identity (72.2% similar) in 295 aa overlap (190-480:6-293) 160 170 180 190 200 210 pF1KB5 SVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYK---DQKKLHRKCAYQILVQV : ::: :: . . :.: .. . .. .. NP_002 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKA 10 20 30 220 230 240 250 260 270 pF1KB5 KEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRG ::.:.: :.. :. .:::::.::::.::...:...: .:: :.: ::.:::: NP_002 KEILTKESNVQEVRCP----VTVCGDVHGQFHDLMELFRIGGKSPDTN-YLFMGDYVDRG 40 50 60 70 80 90 280 290 300 310 320 330 pF1KB5 SFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVF .:::.. : ..:. : ... .::::::. ...:.::: : :: .:.... :...: NP_002 YYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLF 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB5 EWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGR ..:::. ..:... .:::: : . ::: :: ..: .. : :::::::::::. ..: NP_002 DYLPLTALVDGQIFCLHGGL-SPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGW 160 170 180 190 200 400 410 420 430 440 450 pF1KB5 SISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQM .:: ::.. :: :....: . :.: . :.:.. :::. : ::.::::::: . NP_002 GISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC 210 220 230 240 250 260 460 470 480 490 pF1KB5 GNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM ::.:. ..:. . :. .: :: .: NP_002 GNQAAIMELDDT-LKYSFLQFDPAPRRGEPHVTRRTPDYFL 270 280 290 300 >>NP_001290432 (OMIM: 602035) serine/threonine-protein p (307 aa) initn: 605 init1: 489 opt: 758 Z-score: 809.2 bits: 158.5 E(85289): 2.5e-38 Smith-Waterman score: 758; 41.0% identity (70.7% similar) in 307 aa overlap (191-488:1-303) 170 180 190 200 210 220 pF1KB5 VVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVL : :. . .. ..: :.: .:: . NP_001 MAEISDLDRQIEQL-RRCELIKESEVKALC 10 20 230 240 250 260 270 pF1KB5 SKLSTLV--ETTLKETEK-ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGS .: .. :........ .::::: ::::::: ..:...: ::: :.: ::::::: NP_001 AKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETN-YLFMGDFVDRGF 30 40 50 60 70 80 280 290 300 310 320 330 pF1KB5 FSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFE .:::..: :...:. :::.. :.:::::. ...:.::: : :: .. ... .:.:. NP_001 YSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFD 90 100 110 120 130 140 340 350 360 370 380 390 pF1KB5 WLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS .: :. :.::.. .:::: : . :::.:: :.:... : .:::::::::::. .: . NP_001 YLSLSAIIDGKIFCVHGGL-SPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWG 150 160 170 180 190 200 400 410 420 430 440 450 pF1KB5 ISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMG .: ::.. :: ::. : :..:.: :.:.. :::. . .::.:::::: . : NP_001 VSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCG 210 220 230 240 250 260 460 470 480 490 pF1KB5 NKASYIHLQGSDLRPQFHQFTAVPH-----PNVKPMAYANTLLQLGMM : :. ..:. :. .: : :.:. :. ::.: NP_001 NVAAILELD-EHLQKDFIIFEAAPQETRGIPSKKPVADYFL 270 280 290 300 >>NP_002711 (OMIM: 602035) serine/threonine-protein phos (307 aa) initn: 605 init1: 489 opt: 758 Z-score: 809.2 bits: 158.5 E(85289): 2.5e-38 Smith-Waterman score: 758; 41.0% identity (70.7% similar) in 307 aa overlap (191-488:1-303) 170 180 190 200 210 220 pF1KB5 VVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVL : :. . .. ..: :.: .:: . NP_002 MAEISDLDRQIEQL-RRCELIKESEVKALC 10 20 230 240 250 260 270 pF1KB5 SKLSTLV--ETTLKETEK-ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGS .: .. :........ .::::: ::::::: ..:...: ::: :.: ::::::: NP_002 AKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETN-YLFMGDFVDRGF 30 40 50 60 70 80 280 290 300 310 320 330 pF1KB5 FSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFE .:::..: :...:. :::.. :.:::::. ...:.::: : :: .. ... .:.:. NP_002 YSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFD 90 100 110 120 130 140 340 350 360 370 380 390 pF1KB5 WLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS .: :. :.::.. .:::: : . :::.:: :.:... : .:::::::::::. .: . NP_002 YLSLSAIIDGKIFCVHGGL-SPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWG 150 160 170 180 190 200 400 410 420 430 440 450 pF1KB5 ISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMG .: ::.. :: ::. : :..:.: :.:.. :::. . .::.:::::: . : NP_002 VSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCG 210 220 230 240 250 260 460 470 480 490 pF1KB5 NKASYIHLQGSDLRPQFHQFTAVPH-----PNVKPMAYANTLLQLGMM : :. ..:. :. .: : :.:. :. ::.: NP_002 NVAAILELD-EHLQKDFIIFEAAPQETRGIPSKKPVADYFL 270 280 290 300 >>NP_002712 (OMIM: 612725) serine/threonine-protein phos (305 aa) initn: 606 init1: 501 opt: 708 Z-score: 756.5 bits: 148.8 E(85289): 2.1e-35 Smith-Waterman score: 708; 42.4% identity (69.3% similar) in 283 aa overlap (203-480:11-289) 180 190 200 210 220 230 pF1KB5 EDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLV--ETT .. : : : ..:.. . . :. :.. NP_002 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESN 10 20 30 40 240 250 260 270 280 pF1KB5 LKE-TEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGF .. . .::::: ::::::: ..:. .: .:: ::: ::::::: .:.:.. :... NP_002 VQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLAL 50 60 70 80 90 290 300 310 320 330 340 pF1KB5 KLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKV : .::.. :::::::. ...:.::: : ..:: .:. .. ..::. : .: :. .. NP_002 KAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQI 100 110 120 130 140 150 350 360 370 380 390 400 pF1KB5 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGP : .:::: : : :::.:: ::::.. : .: .:::.::::. . .:: ::.. :: NP_002 LCVHGGL-SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGA 160 170 180 190 200 210 410 420 430 440 450 460 pF1KB5 DVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD ::. :.. ::: : :.:.. :::. . :::.:::::: . :: :: . .. . NP_002 KVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVN 220 230 240 250 260 270 470 480 490 pF1KB5 LR-PQFHQFTAVPHPNVKPMAYANTLLQLGMM : :.. : ::: NP_002 TREPKL--FRAVPDSERVIPPRTTTPYFL 280 290 300 >>NP_002701 (OMIM: 176914) serine/threonine-protein phos (323 aa) initn: 670 init1: 425 opt: 707 Z-score: 755.0 bits: 148.6 E(85289): 2.6e-35 Smith-Waterman score: 707; 41.7% identity (68.5% similar) in 276 aa overlap (226-499:47-317) 200 210 220 230 240 250 pF1KB5 QWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEK-ITVCGDTHGQFYDLLNIF : . : : : . .::: :::.:::: .: NP_002 LEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLF 20 30 40 50 60 70 260 270 280 290 300 310 pF1KB5 ELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYG : .:.: :.: :.: ::.::::. :.:.: :...:. ::..: ::::::: ..:.::: NP_002 EYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYG 80 90 100 110 120 130 320 330 340 350 360 370 pF1KB5 FEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQ : : : .:. .... :.. :. ::.: .. :.. :::: : : ....::.: : . NP_002 FYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTD 140 150 160 170 180 190 380 390 400 410 420 430 pF1KB5 PPDSGPMCDLLWSDPQPQN-GRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEG ::.: .::::::::. . : . . :::: :: .:. ::....:: : :.:.: .: NP_002 VPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDG 200 210 220 230 240 250 440 450 460 470 480 490 pF1KB5 YEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTL :: . ::.::::::: .. : .... .. . : .:. . : . :: : . NP_002 YEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET-LMCSFQILK--PAEKKKPNATRPVT 260 270 280 290 300 310 pF1KB5 LQLGMM ::. NP_002 PPRGMITKQAKK 320 >>NP_002699 (OMIM: 176875) serine/threonine-protein phos (330 aa) initn: 674 init1: 429 opt: 707 Z-score: 754.9 bits: 148.6 E(85289): 2.6e-35 Smith-Waterman score: 708; 40.9% identity (69.6% similar) in 276 aa overlap (226-487:47-319) 200 210 220 230 240 250 pF1KB5 QWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEK-ITVCGDTHGQFYDLLNIF : . : : : . .::: :::.:::: .: NP_002 LEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLF 20 30 40 50 60 70 260 270 280 290 300 310 pF1KB5 ELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYG : .:.: :.: :.: ::.::::. :.:.: :...:. ::..: ::::::: ..:.::: NP_002 EYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYG 80 90 100 110 120 130 320 330 340 350 360 370 pF1KB5 FEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQ : : : .:. .... :.. :. ::.: .. :.. :::: : : ....::.: : . NP_002 FYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTD 140 150 160 170 180 190 380 390 400 410 420 430 pF1KB5 PPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEG ::.: .::::::::. . .: . . :::: :: .:. ::....:: : :.:.: .: NP_002 VPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDG 200 210 220 230 240 250 440 450 460 470 480 pF1KB5 YEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD------LRP------QFHQFTAVPH :: . ::.::::::: .. : .... .. . :.: .. ::... . NP_002 YEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGL-N 260 270 280 290 300 310 490 pF1KB5 PNVKPMAYANTLLQLGMM :. .:. NP_002 PGGRPITPPRNSAKAKK 320 330 499 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 10:37:32 2016 done: Sat Nov 5 10:37:33 2016 Total Scan time: 8.760 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]