FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5894, 524 aa 1>>>pF1KB5894 524 - 524 aa - 524 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3099+/-0.00046; mu= 18.6595+/- 0.028 mean_var=77.2317+/-16.127, 0's: 0 Z-trim(109.4): 156 B-trim: 0 in 0/50 Lambda= 0.145941 statistics sampled from 17399 (17559) to 17399 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.206), width: 16 Scan time: 8.230 The best scores are: opt bits E(85289) NP_000331 (OMIM: 125853,138160,227810) solute carr ( 524) 3397 725.5 9.5e-209 XP_011511389 (OMIM: 125853,138160,227810) PREDICTE ( 509) 3177 679.2 8.2e-195 NP_001265587 (OMIM: 125853,138160,227810) solute c ( 405) 2598 557.2 3.4e-158 XP_011511391 (OMIM: 125853,138160,227810) PREDICTE ( 351) 2281 490.4 3.8e-138 NP_001265588 (OMIM: 125853,138160,227810) solute c ( 351) 2281 490.4 3.8e-138 NP_006507 (OMIM: 138140,143090,608885) solute carr ( 492) 1736 375.7 1.7e-103 NP_001033 (OMIM: 138190) solute carrier family 2, ( 509) 1651 357.9 4.3e-98 NP_008862 (OMIM: 138170) solute carrier family 2, ( 496) 1595 346.1 1.5e-94 XP_011518865 (OMIM: 611039) PREDICTED: solute carr ( 497) 1543 335.1 2.9e-91 XP_005253374 (OMIM: 611039) PREDICTED: solute carr ( 497) 1543 335.1 2.9e-91 XP_016874335 (OMIM: 611039) PREDICTED: solute carr ( 497) 1543 335.1 2.9e-91 XP_016874336 (OMIM: 611039) PREDICTED: solute carr ( 497) 1543 335.1 2.9e-91 XP_005253372 (OMIM: 611039) PREDICTED: solute carr ( 497) 1543 335.1 2.9e-91 NP_001273164 (OMIM: 611039) solute carrier family ( 497) 1543 335.1 2.9e-91 NP_001273163 (OMIM: 611039) solute carrier family ( 497) 1543 335.1 2.9e-91 XP_011518864 (OMIM: 611039) PREDICTED: solute carr ( 497) 1543 335.1 2.9e-91 NP_001273162 (OMIM: 611039) solute carrier family ( 520) 1543 335.1 3e-91 NP_703150 (OMIM: 611039) solute carrier family 2, ( 520) 1543 335.1 3e-91 XP_016874333 (OMIM: 611039) PREDICTED: solute carr ( 521) 1543 335.1 3.1e-91 XP_016874330 (OMIM: 611039) PREDICTED: solute carr ( 521) 1543 335.1 3.1e-91 XP_016874331 (OMIM: 611039) PREDICTED: solute carr ( 521) 1543 335.1 3.1e-91 XP_016874334 (OMIM: 611039) PREDICTED: solute carr ( 521) 1543 335.1 3.1e-91 XP_016874332 (OMIM: 611039) PREDICTED: solute carr ( 521) 1543 335.1 3.1e-91 NP_001273166 (OMIM: 611039) solute carrier family ( 535) 1543 335.1 3.1e-91 NP_001273165 (OMIM: 611039) solute carrier family ( 411) 1442 313.8 6.4e-85 XP_011518866 (OMIM: 611039) PREDICTED: solute carr ( 411) 1442 313.8 6.4e-85 XP_011518867 (OMIM: 611039) PREDICTED: solute carr ( 411) 1442 313.8 6.4e-85 NP_001315549 (OMIM: 138230) solute carrier family ( 457) 1133 248.8 2.7e-65 NP_001315548 (OMIM: 138230) solute carrier family ( 501) 1133 248.8 2.9e-65 NP_003030 (OMIM: 138230) solute carrier family 2, ( 501) 1133 248.8 2.9e-65 XP_005263548 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857622 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857624 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857623 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857625 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857629 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857630 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857627 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857626 (OMIM: 138230) PREDICTED: solute carr ( 501) 1133 248.8 2.9e-65 XP_016857631 (OMIM: 138230) PREDICTED: solute carr ( 442) 1047 230.6 7.4e-60 NP_997303 (OMIM: 610371) solute carrier family 2, ( 512) 1027 226.5 1.5e-58 NP_001315550 (OMIM: 138230) solute carrier family ( 354) 928 205.5 2.2e-52 XP_011539126 (OMIM: 610371) PREDICTED: solute carr ( 517) 907 201.2 6.2e-51 XP_011512161 (OMIM: 606142,612076) PREDICTED: solu ( 538) 890 197.6 7.6e-50 NP_001001290 (OMIM: 606142,612076) solute carrier ( 511) 889 197.4 8.5e-50 XP_011512162 (OMIM: 606142,612076) PREDICTED: solu ( 537) 889 197.4 8.8e-50 NP_064425 (OMIM: 606142,612076) solute carrier fam ( 540) 889 197.4 8.9e-50 XP_006714031 (OMIM: 606142,612076) PREDICTED: solu ( 563) 889 197.5 9.2e-50 XP_016863946 (OMIM: 606142,612076) PREDICTED: solu ( 609) 889 197.5 9.7e-50 NP_001020109 (OMIM: 610367) solute carrier family ( 496) 836 186.3 1.9e-46 >>NP_000331 (OMIM: 125853,138160,227810) solute carrier (524 aa) initn: 3397 init1: 3397 opt: 3397 Z-score: 3868.7 bits: 725.5 E(85289): 9.5e-209 Smith-Waterman score: 3397; 100.0% identity (100.0% similar) in 524 aa overlap (1-524:1-524) 10 20 30 40 50 60 pF1KB5 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT 430 440 450 460 470 480 490 500 510 520 pF1KB5 FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV :::::::::::::::::::::::::::::::::::::::::::: NP_000 FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV 490 500 510 520 >>XP_011511389 (OMIM: 125853,138160,227810) PREDICTED: s (509 aa) initn: 3177 init1: 3177 opt: 3177 Z-score: 3618.5 bits: 679.2 E(85289): 8.2e-195 Smith-Waterman score: 3177; 100.0% identity (100.0% similar) in 489 aa overlap (36-524:21-509) 10 20 30 40 50 60 pF1KB5 VTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTD :::::::::::::::::::::::::::::: XP_011 MHLNRDKGCPRGRHKAILACQVIISHYRHVLGVPLDDRKAINNYVINSTD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 KAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALR 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 GALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 LYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPIL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 VALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 RSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 FFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVP 420 430 440 450 460 470 490 500 510 520 pF1KB5 ETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV ::::::::::::::::::::::::::::::::::::::: XP_011 ETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV 480 490 500 >>NP_001265587 (OMIM: 125853,138160,227810) solute carri (405 aa) initn: 2598 init1: 2598 opt: 2598 Z-score: 2961.1 bits: 557.2 E(85289): 3.4e-158 Smith-Waterman score: 2598; 99.8% identity (100.0% similar) in 403 aa overlap (122-524:3-405) 100 110 120 130 140 150 pF1KB5 LITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSH :.:::::::::::::::::::::::::::: NP_001 MHLNRIKAMLVANILSLVGALLMGFSKLGPSH 10 20 30 160 170 180 190 200 210 pF1KB5 ILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFI 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB5 LGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTK 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB5 DINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB5 TAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLN 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB5 KFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVA 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB5 LCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKSGSAHRPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKSGSAHRPKA 340 350 360 370 380 390 520 pF1KB5 AVEMKFLGATETV ::::::::::::: NP_001 AVEMKFLGATETV 400 >>XP_011511391 (OMIM: 125853,138160,227810) PREDICTED: s (351 aa) initn: 2281 init1: 2281 opt: 2281 Z-score: 2601.2 bits: 490.4 E(85289): 3.8e-138 Smith-Waterman score: 2281; 100.0% identity (100.0% similar) in 351 aa overlap (174-524:1-351) 150 160 170 180 190 200 pF1KB5 FSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILIS :::::::::::::::::::::::::::::: XP_011 MYIGEIAPTALRGALGTFHQLAIVTGILIS 10 20 30 210 220 230 240 250 260 pF1KB5 QIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 RGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIF 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 YYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFM 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 SVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSN 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 WTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKS 280 290 300 310 320 330 510 520 pF1KB5 GSAHRPKAAVEMKFLGATETV ::::::::::::::::::::: XP_011 GSAHRPKAAVEMKFLGATETV 340 350 >>NP_001265588 (OMIM: 125853,138160,227810) solute carri (351 aa) initn: 2281 init1: 2281 opt: 2281 Z-score: 2601.2 bits: 490.4 E(85289): 3.8e-138 Smith-Waterman score: 2281; 100.0% identity (100.0% similar) in 351 aa overlap (174-524:1-351) 150 160 170 180 190 200 pF1KB5 FSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILIS :::::::::::::::::::::::::::::: NP_001 MYIGEIAPTALRGALGTFHQLAIVTGILIS 10 20 30 210 220 230 240 250 260 pF1KB5 QIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB5 RGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIF 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB5 YYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFM 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB5 SVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSN 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB5 WTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKS 280 290 300 310 320 330 510 520 pF1KB5 GSAHRPKAAVEMKFLGATETV ::::::::::::::::::::: NP_001 GSAHRPKAAVEMKFLGATETV 340 350 >>NP_006507 (OMIM: 138140,143090,608885) solute carrier (492 aa) initn: 1857 init1: 1724 opt: 1736 Z-score: 1979.0 bits: 375.7 E(85289): 1.7e-103 Smith-Waterman score: 1809; 53.4% identity (79.1% similar) in 521 aa overlap (5-524:7-492) 10 20 30 40 50 pF1KB5 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINN :.:: :...: :::::.::::. :::::::.:: : .. .. NP_006 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFY---------NQTWVHR 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 YVINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWL : . . ::: .: ::::::. :.:::: .:: : . NP_006 Y---GESILPTT----------------------LTTLWSLSVAIFSVGGMIGSFSVGLF 60 70 80 120 130 140 150 160 170 pF1KB5 GDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGE . .:: ..::. :.:..:.:.:::::::: : ..: :: : :.:::: .:.::::.:: NP_006 VNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGE 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB5 IAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFF ..::::::::::.:::.::.::::.:..::. :.:: ::: .::.. . :.:: ..: : NP_006 VSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPF 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 CPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNS ::::::.: :. .:: .::. ::.::: :::.:..::..: .. :.::.:..:: . NP_006 CPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSP 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 SYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVF .::::::.:..:...::.::::..::::::::. ::...::::::: : :: .::.::.: NP_006 AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLF 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 LVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPI .::.::::.: :::..:: :::.:...:.::... ::::.:..::: ::.:::.::::: NP_006 VVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPI 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 PWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTL :::.:::.:::::::::.:.:.::::: ::::..::::. ..::::::..:. .:. : . NP_006 PWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFI 390 400 410 420 430 440 480 490 500 510 520 pF1KB5 FTFFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEM-KFLGATETV ::.::::::::..:.:::. : ...:... :. :. . ::: : NP_006 FTYFKVPETKGRTFDEIASGF-RQGGASQSDKTPEELFHPLGADSQV 450 460 470 480 490 >>NP_001033 (OMIM: 138190) solute carrier family 2, faci (509 aa) initn: 1784 init1: 1623 opt: 1651 Z-score: 1882.1 bits: 357.9 E(85289): 4.3e-98 Smith-Waterman score: 1744; 52.9% identity (79.1% similar) in 522 aa overlap (3-522:17-507) 10 20 30 40 pF1KB5 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHV- ...::::::..:..:::::.::::.::::::::.:: . : .. NP_001 MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 LGVPLDDRKAINNYVINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFA :: :.. : :. :. : .: ::.:::. :. NP_001 LG-----RQG---------PEGPS---SIPPGT--------------LTTLWALSVAIFS 70 80 110 120 130 140 150 160 pF1KB5 VGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYC :::: .::. : ... ::: .:::: :.:...:. :::... . :. ..: :: . : : NP_001 VGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYS 90 100 110 120 130 140 170 180 190 200 210 220 pF1KB5 GLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLS :: :::::::.:::::: :::::::..::::: ::::.:..::: .::. .:: .::::. NP_001 GLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLT 150 160 170 180 190 200 230 240 250 260 270 280 pF1KB5 GVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASS . :.:: .:: ::::::::::: . : :..::::: :. ::. . :.. :... NP_001 VLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLER 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB5 EQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGV :. .:..::. . ..:::...:..:...::.::::..::::::::.:::...:.:::::. NP_001 ERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB5 GAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIF :.:: ::: :::.:::.::::.: :.:..:: :::.:.:.:.::.. :::::..::: NP_001 GVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIF 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB5 LFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYV ::.::::::::::::.:::.:::::::::.:.:.::::: :::... :::.:. :::: NP_001 GFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYV 390 400 410 420 430 440 470 480 490 500 510 520 pF1KB5 FFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKK-SGSAHRPKAAVEMKFLGATETV :.::: .::.: .:::..::::.:..:..:.: :.. : .. : ..:...:: : NP_001 FLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDEND 450 460 470 480 490 500 >>NP_008862 (OMIM: 138170) solute carrier family 2, faci (496 aa) initn: 1747 init1: 1585 opt: 1595 Z-score: 1818.5 bits: 346.1 E(85289): 1.5e-94 Smith-Waterman score: 1677; 50.6% identity (78.1% similar) in 508 aa overlap (1-508:1-474) 10 20 30 40 50 60 pF1KB5 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV : .::: .:.:.. .:..:::::::. ::::::...: .. ::. NP_008 MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKII--------------KEFINK-- 10 20 30 40 70 80 90 100 110 120 pF1KB5 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD :.. . : :. :.: ::::::. :.:::: .:: : . . NP_008 --------TLTDKGNAPPSEV----------LLTSLWSLSVAIFSVGGMIGSFSVGLFVN 50 60 70 80 130 140 150 160 170 180 pF1KB5 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA .:: ..::..:.:...:. .::. :.. : ..: :: . ::.::: .:.::::::::. NP_008 RFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEIS 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP :::::::.::..::.::.:::..::.:::::::. .:: .:::.. . ::::: : ::: NP_008 PTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCP 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB5 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY ::::.: :. :: .::: :.:: : .::..::.::. : . :.:..:....:: ::: NP_008 ESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSY 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV ::::.....:...::.::::..:::::.::. ::...:.:::::.:.:: .::.::.::: NP_008 RQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLV 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB5 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW :.::::.: .::..:: :. .:.:.:.: .... ::.: . ::..::.::::::::::: NP_008 ERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPW 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB5 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT :.:::.:::::::::.:.:. :::: ::.:.: : : . : :::..:.: :..: :: NP_008 FIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFT 390 400 410 420 430 440 490 500 510 520 pF1KB5 FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV :::::::.:..::.:. :. .. .: : NP_008 FFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMEMNSIEPAKETTTNV 450 460 470 480 490 >>XP_011518865 (OMIM: 611039) PREDICTED: solute carrier (497 aa) initn: 1682 init1: 1533 opt: 1543 Z-score: 1759.3 bits: 335.1 E(85289): 2.9e-91 Smith-Waterman score: 1614; 49.5% identity (76.9% similar) in 503 aa overlap (6-508:7-475) 10 20 30 40 50 pF1KB5 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNY :: .:.:.. .:..:::::::. ::::::. .: .. ::. XP_011 MDNRQNVTPALIFAITVATIGSFQFGYNTGVINAPETII--------------KEFINK- 10 20 30 40 60 70 80 90 100 110 pF1KB5 VINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLG :.. . : :. :.: ::::::. :.:::: .:: : . XP_011 ---------TLTDKANAPPSEV----------LLTNLWSLSVAIFSVGGMIGSFSVGLFV 50 60 70 80 120 130 140 150 160 170 pF1KB5 DTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEI . .:: ..::..:.:. .:. :::. :.. : ..: :: . ::.::: .:.:::::::: XP_011 NRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB5 APTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFC .:::::::.::..::.:: :::..::.:::.:::. .:: .:::.. . ::::: : : XP_011 SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCC 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 PESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSS :::::.: :. .: .: . :.:: : .::..::.::. : . :.:..:....:: :: XP_011 PESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 YRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFL :::::.....:...::.::::..:::::.::. ::...:.::::..:.:: .:: .:.:: XP_011 YRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 VEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIP ::.::::.: .::..:: :. .:.:.:.: :... ::.: . ::..::. ::::::::: XP_011 VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIP 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 WFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLF ::.:::.:::::::::.:.:. :::: ::.:.: : : . : :::..:.: :..: : XP_011 WFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAF 390 400 410 420 430 440 480 490 500 510 520 pF1KB5 TFFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV ::::::::.:..::.:. :. .. .: : XP_011 TFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV 450 460 470 480 490 >>XP_005253374 (OMIM: 611039) PREDICTED: solute carrier (497 aa) initn: 1682 init1: 1533 opt: 1543 Z-score: 1759.3 bits: 335.1 E(85289): 2.9e-91 Smith-Waterman score: 1614; 49.5% identity (76.9% similar) in 503 aa overlap (6-508:7-475) 10 20 30 40 50 pF1KB5 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNY :: .:.:.. .:..:::::::. ::::::. .: .. ::. XP_005 MDNRQNVTPALIFAITVATIGSFQFGYNTGVINAPETII--------------KEFINK- 10 20 30 40 60 70 80 90 100 110 pF1KB5 VINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLG :.. . : :. :.: ::::::. :.:::: .:: : . XP_005 ---------TLTDKANAPPSEV----------LLTNLWSLSVAIFSVGGMIGSFSVGLFV 50 60 70 80 120 130 140 150 160 170 pF1KB5 DTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEI . .:: ..::..:.:. .:. :::. :.. : ..: :: . ::.::: .:.:::::::: XP_005 NRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB5 APTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFC .:::::::.::..::.:: :::..::.:::.:::. .:: .:::.. . ::::: : : XP_005 SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCC 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 PESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSS :::::.: :. .: .: . :.:: : .::..::.::. : . :.:..:....:: :: XP_005 PESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSS 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 YRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFL :::::.....:...::.::::..:::::.::. ::...:.::::..:.:: .:: .:.:: XP_005 YRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 VEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIP ::.::::.: .::..:: :. .:.:.:.: :... ::.: . ::..::. ::::::::: XP_005 VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIP 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 WFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLF ::.:::.:::::::::.:.:. :::: ::.:.: : : . : :::..:.: :..: : XP_005 WFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAF 390 400 410 420 430 440 480 490 500 510 520 pF1KB5 TFFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV ::::::::.:..::.:. :. .. .: : XP_005 TFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV 450 460 470 480 490 524 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:36:55 2016 done: Sat Nov 5 18:36:57 2016 Total Scan time: 8.230 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]