FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5897, 837 aa 1>>>pF1KB5897 837 - 837 aa - 837 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.4998+/-0.00125; mu= -3.1537+/- 0.076 mean_var=495.0815+/-100.073, 0's: 0 Z-trim(113.9): 29 B-trim: 0 in 0/55 Lambda= 0.057642 statistics sampled from 14518 (14542) to 14518 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.447), width: 16 Scan time: 4.790 The best scores are: opt bits E(32554) CCDS11417.1 KAT2A gene_id:2648|Hs108|chr17 ( 837) 5659 485.8 1.3e-136 CCDS2634.1 KAT2B gene_id:8850|Hs108|chr3 ( 832) 3941 343.0 1.3e-93 >>CCDS11417.1 KAT2A gene_id:2648|Hs108|chr17 (837 aa) initn: 5659 init1: 5659 opt: 5659 Z-score: 2566.2 bits: 485.8 E(32554): 1.3e-136 Smith-Waterman score: 5659; 100.0% identity (100.0% similar) in 837 aa overlap (1-837:1-837) 10 20 30 40 50 60 pF1KB5 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE 730 740 750 760 770 780 790 800 810 820 830 pF1KB5 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 790 800 810 820 830 >>CCDS2634.1 KAT2B gene_id:8850|Hs108|chr3 (832 aa) initn: 3534 init1: 2373 opt: 3941 Z-score: 1794.2 bits: 343.0 E(32554): 1.3e-93 Smith-Waterman score: 3941; 71.6% identity (86.4% similar) in 821 aa overlap (26-837:22-832) 10 20 30 40 50 60 pF1KB5 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT : : :.::. : :.: : .: :: ::..:. CCDS26 MSEAGGAGPGGCGAGAGAGAGPGALP-PQPAALP---PAP-PQGSPCAAAAGGSGA 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC ::... ..::.. :. : . : . .:::.:. :::::::::::.:::::.:.::: CCDS26 CGPATAVAAAGTAEGPGGGG---SARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKC 60 70 80 90 100 130 140 150 160 170 pF1KB5 NGWKNPKP-PTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDV ::::::.: :: :: :::: ..:.: :::: : :: ::::::::::.:.:::::.:.:: CCDS26 NGWKNPNPSPTPPRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 ENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSL-GSPPFEKPNIEQGVLNF : :: ::::::.::::::::::::::: ::: .::::::: .::::::.::::: :: CCDS26 EYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 VQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCY :::::::: .::::. ::.:::: .:::.::.:.: : :: .:.. :: :::::::: CCDS26 VQYKFSHLPAKERQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 CHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPK :.::: ::::::::::.::::.::::.::: ::::::. : ::::: :::::::::::: CCDS26 CNVPQFCDSLPRYETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPK 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB5 FLSMLEEEIYGANSPIWESGFTMPPSE----GTQLVPRPASVSAAVV---PSTPIFSPSM ::::::::.:. :::::.. : :. : : : : :.... :. . .:. CCDS26 FLSMLEEEVYSQNSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPN- 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB5 GGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAA .::.: :.: : ::::: . .. .::.::. ::::::::::.:::: ::::::: CCDS26 -AGSSSPACKASSGLEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAA 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB5 MLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQL ::::::..:::..::::.::::::::.:::::.::::. : :...:.::::::::::::: CCDS26 MLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQL 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB5 PRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYG ::::::::.:::::::::::::::::::::::::::::.::::::::::::::::::::: CCDS26 PRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYG 530 540 550 560 570 580 600 610 620 630 640 650 pF1KB5 THLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLM ::::::::::::::.:: ::::::::::::::::::::.::.::..:.:::::::::::: CCDS26 THLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLM 590 600 610 620 630 640 660 670 680 690 700 710 pF1KB5 ECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGI :::::::::::.: :::::::::::::::::::::::::::::::.::::::.::.::: CCDS26 GCELNPRIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGI 650 660 670 680 690 700 720 730 740 750 760 770 pF1KB5 RETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRF ::::::: ::::.:: .::::::.:::..: :.::: ::::::::::..::: ::::::: CCDS26 RETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRF 710 720 730 740 750 760 780 790 800 810 820 830 pF1KB5 PIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE :.:::::.:::..::::..:::.::::::..::.:::::.::: .::. :::::. :.:: CCDS26 PMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 770 780 790 800 810 820 pF1KB5 GGLIDK .::::: CCDS26 AGLIDK 830 837 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:23:55 2016 done: Sat Nov 5 16:23:56 2016 Total Scan time: 4.790 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]